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Showing 1–24 of 96 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Gratitude Intervention Clear all
Completed Not applicable Interventional Results available

Positive Valence System Enhancement Treatment for Anxiety and Depression: Clinical Efficacy and Neural Changes

NCT02330627
View directory record Official record
Conditions
Anxiety Disorders and Symptoms, Depression
Interventions
Positive Valence System Treatment
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 55 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 7, 2021 · Synced Sep 6, 2026, 3:14 AM EDT
Not yet recruiting Not applicable Interventional

Algorithm-informed Decision-making to Advance Pain Treatment

NCT07731750
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
Algorithmically informed randomization (taking into account phenotypes), Physical Therapy (PT) and Exercise, Cognitive-Behavioral Therapy for Pain (PRISM-CBT), mHealth Acupressure Self-Management:, Duloxetine
Device · Behavioral · Drug
Lead sponsor
University of Michigan
Other
Eligibility
25 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 6, 2026, 3:14 AM EDT
Completed Not applicable Interventional

Trial of a Positive Psychology Intervention in Major Depressive Disorder

NCT02004145
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Positive Psychology, Control Condition
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 18, 2016 · Synced Sep 6, 2026, 3:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Positive Affect Regulation sKills at Northwestern University

NCT04367922
View directory record Official record
Conditions
Anxiety, Depression, Social Isolation
Interventions
Positive Emotion Skills Course
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 23, 2024 · Synced Sep 6, 2026, 3:14 AM EDT
Completed Not applicable Interventional Results available

Developing a Positive Psychology Intervention to Promote Health Behaviors in Metabolic Syndrome: Proof-of Concept Trial

NCT03473886
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Intervention arm: PP-MI
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 100 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Sep 6, 2026, 3:14 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Randomized Controlled Trial Testing the Effect of the Youth Mindful Awareness Program on Negative Affect (YMAP2).

NCT06526052
View directory record Official record
Conditions
Prevention, Control
Interventions
Mindfulness Program, Active Comparator
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
12 Years to 17 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
3
States / cities
Los Angeles, California • Evanston, Illinois • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 19, 2025 · Synced Sep 6, 2026, 3:14 AM EDT
Completed Not applicable Interventional

Intervention for (Those) Recently Informed of Seropositive Status (IRISS)

NCT00720733
View directory record Official record
Conditions
HIV Infections
Interventions
Skills-Building Intervention, Personal Interview Group
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2015 · Synced Sep 6, 2026, 3:14 AM EDT
Completed Not applicable Interventional Results available

Researching Emotions And Cardiac Health (REACH): Phase II

NCT02938052
View directory record Official record
Conditions
Congestive Heart Failure, Emotions, Patient Compliance
Interventions
PP-based health behavior intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 31, 2021 · Synced Sep 6, 2026, 3:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Culturally Tailored Mindfulness-Positive Psychological Intervention Using Virtual Reality

NCT06019416
View directory record Official record
Conditions
Mental Health Issue
Interventions
culturally tailored mindfulness-positive psychological intervention
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
60 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
3
States / cities
Chicago, Illinois • Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 30, 2023 · Synced Sep 6, 2026, 3:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Testing a Positive Psychology-based Intervention for Couples Coping With Stroke

NCT03335358
View directory record Official record
Conditions
Stroke, Depression, Depressive Symptoms, Post-stroke Depression
Interventions
Dyadic (couples-based) positive psychology intervention
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 18, 2020 · Synced Sep 6, 2026, 3:14 AM EDT
Recruiting Not applicable Interventional

Journaling Intervention for Temporomandibular Disorder (TMD) and Chronic Overlapping Pain

NCT06977100
View directory record Official record
Conditions
Temporomandibular Disorders (TMD)
Interventions
Gratitude, General Wellness
Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 6, 2026, 3:14 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Emotional Well-being and Measures of Healthy Aging

NCT07334106
View directory record Official record
Conditions
Aging, Aging, Healthy, Aging Well, Aging, Biological
Interventions
Positive Emotion Skills Intervention
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
40 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 11, 2026 · Synced Sep 6, 2026, 3:14 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers Results available

Positive Psychology Intervention for Patients Post-bariatric Surgery and Their Partners

NCT05958615
View directory record Official record
Conditions
Obesity, Morbid
Interventions
Reimagining Us in the Context of Bariatric Surgery (ReConnect)
Behavioral
Lead sponsor
Larissa McGarrity, Ph.D.
Other
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Sep 6, 2026, 3:14 AM EDT
Completed Not applicable Interventional

Evaluating Procedures for a Study of the AYA Survivors Coping and Emotional Needs Toolkit

NCT06420193
View directory record Official record
Conditions
Depression, Cancer, Adolescent, Young Adult, Adult
Interventions
AYA Survivors Coping and Emotional Needs Toolkit (ASCENT)
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
15 Years to 39 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 9, 2025 · Synced Sep 6, 2026, 3:14 AM EDT
Completed Not applicable Interventional Results available

Evaluating Digital Micro-Interventions to Reduce Distress and Increase Wellbeing in Breast Cancer Survivors

NCT07160439
View directory record Official record
Conditions
Mental Health Issue, Breast Cancer
Interventions
Digital Micro-Interventions
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 6, 2026, 3:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Psychological Well-being and Burnout in Healthcare Workers During the COVID-19 (Coronavirus Disease 2019) Pandemic

NCT05394051
View directory record Official record
Conditions
COVID-19, Burnout, Burnout, Professional, Work-related Illness, Work-Related Stress, SARS-CoV-2 Infection
Interventions
Positive Affect Regulation sKills (PARK)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
555 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Sep 6, 2026, 3:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Grateful Strides Toward Physical Activity and Well-Being for Black Breast Cancer Survivors

NCT05473026
View directory record Official record
Conditions
Cancer Survivors, African Americans, Women, Psychology, Positive, Cardiometabolic Syndrome, Exercise, Feasibility Studies, Breast Neoplasm Female
Interventions
Gratitude Intervention
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
50 Years to 99 Years · Female only
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 6, 2026, 3:14 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Mobile-Web Emotion Self-management Tool

NCT02346591
View directory record Official record
Conditions
Stress, Depression
Interventions
Jauntly, Online stress management information
Behavioral
Lead sponsor
Oregon Center for Applied Science, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
298 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 26, 2015 · Synced Sep 6, 2026, 3:14 AM EDT
Not listed Not applicable Interventional

Developing a Positive Psychology Intervention to Promote Health Behaviors in Metabolic Syndrome: RCT

NCT04039165
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
PP-MI Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 100 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Revere, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 18, 2022 · Synced Sep 6, 2026, 3:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Scaling Well-Being for Educators During COVID-19

NCT05561933
View directory record Official record
Conditions
Anxiety, Depression
Interventions
Healthy Minds Program Foundations Training
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
829 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Sep 6, 2026, 3:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Change in Social Media Use and Well-being Among College Students Receiving a One-week Exercise or Mindfulness Intervention

NCT06143852
View directory record Official record
Conditions
Social Media Addiction, Depression, Anxiety, Well-Being, Psychological
Interventions
Mindfulness, Social Media Reduction + Exercise
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Sep 6, 2026, 3:14 AM EDT
Completed Not applicable Interventional

The Effects of Journaling on Health-Related Mood and Clinical Outcomes in Post-MI Patients

NCT02481544
View directory record Official record
Conditions
Myocardial Infarction, Psychosocial Factors
Interventions
Gratitude Journaling Plus SOC, Memorable Events Journaling Plus SOC
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
35 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 7, 2019 · Synced Sep 6, 2026, 3:14 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Change in Social Media Use and Well-being Among College Students Receiving a Two-week Exercise or Mindfulness Intervention

NCT07097545
View directory record Official record
Conditions
Social Media Addiction, Anxiety, Depression Disorder, Wellbeing
Interventions
Mindfulness, Social Media Reduction, Exercise
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Sep 6, 2026, 3:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

In the Mirror: Functional Appreciated Bodies (IM FAB)

NCT04118972
View directory record Official record
Conditions
Eating Disorder Symptom, Body Image Disturbance
Interventions
Mirror exposure and text prompt responses
Behavioral
Lead sponsor
Union College, New York
Other
Eligibility
18 Years and older · Female only
Enrollment
275 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
2
States / cities
Albany, New York • Schenectady, New York
Source: ClinicalTrials.gov public record
Updated Dec 11, 2023 · Synced Sep 6, 2026, 3:14 AM EDT