Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 6, 2026, 7:42 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 409–432 of 9,540 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: HEARTS Clear all

Conditions: Pulmonary Hypertension
Interventions: Optison (Perflutren Protein-Type A Microspheres Injectable Suspension), Dextrose; Drug
Lead sponsor: GE Healthcare; Industry
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Elliott, Maryland

Conditions: Aortic Stenosis
Interventions: SAPIEN S3 valve; Device
Lead sponsor: Edwards Lifesciences; Industry
Eligibility: Not listed
Enrollment: 1,822 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 55
States / cities: La Jolla, California • Los Angeles, California • Palo Alto, California + 46 more

Conditions: Atrial Fibrillation, Stroke
Interventions: Catheter Ablation, Market-approved AVNB, OAC and AAD; Device · Drug
Lead sponsor: Kansas City Heart Rhythm Research Foundation; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 7
States / cities: Overland Park, Kansas • Independence, Missouri • Kansas City, Missouri

Conditions: Epigastric Pain, Retrosternal Pain, Esophagitis, Gastrointestinal Symptoms
Interventions: Not listed
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 5 Years to 17 Years
Enrollment: 77 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2015
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Cardiac Conduction Disorders Requiring Permanent Pacing in Patients With Prior or Planned Tricuspid Valve Intervention
Interventions: Pacemaker; Device
Lead sponsor: Minneapolis Heart Institute Foundation; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Sepsis
Interventions: Suspected Sepsis Group - Diagnostic Measurements, Control Group - Diagnostic Measurements; Diagnostic Test
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Heart Failure, Muscle Atrophy
Interventions: Ensure Max Protein, Ensure Original; Dietary Supplement
Lead sponsor: Tufts Medical Center; Other
Eligibility: 18 Years to 100 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 2
States / cities: Boston, Massachusetts • Cleveland, Ohio

Conditions: Bloodloss, Surgical Procedures, Operative
Interventions: Ecallantide, Cyklokapron(R); Drug
Lead sponsor: Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA); Industry
Eligibility: 18 Years to 85 Years
Enrollment: 243 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Coronary Artery Disease
Interventions: LiveCare, Text Messages, Conventional Care; Device · Behavioral · Other
Lead sponsor: University of California, Davis; Other
Eligibility: Not listed
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Heart Failure
Interventions: Clinical Reminder; Other
Lead sponsor: VA Palo Alto Health Care System; Federal
Eligibility: 18 Years to 120 Years
Enrollment: 115 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Heart Transplant
Interventions: Belatacept, Tacrolimus, Mycophenolate Mofetil/Sodium, Prednisone; Drug
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 76 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 8
States / cities: Los Angeles, California • Tampa, Florida • Atlanta, Georgia + 4 more

Conditions: Heart Failure NYHA Class III, Heart Failure
Interventions: Cordella PA Sensor System, Standard of Care Pharmacologic Therapy; Device · Drug
Lead sponsor: Endotronix, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 2,150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: Naperville, Illinois

Conditions: Congenital Heart Defects
Interventions: Not listed
Lead sponsor: Emory University; Other
Eligibility: Up to 21 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2006
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Vasovagal Syncope, Postural Tachycardia Syndrome
Interventions: Phenylephrine, L-Ng-monomethyl Arginine (L-NMMA); Drug
Lead sponsor: New York Medical College; Other
Eligibility: 14 Years to 29 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2022
U.S. locations: 1
States / cities: Hawthorne, New York

Conditions: Left Ventricular Diastolic Dysfunction
Interventions: BNP (nesiritide), Placebo; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Cardiopulmonary, Exercise, Cognitive Performance, Covid19
Interventions: Cardiopulmonary Exercise Test, Cognitive Performance Test; Other
Lead sponsor: Baylor Research Institute; Other
Eligibility: 18 Years to 39 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Frisco, Texas

Conditions: Heart Failure
Interventions: Microtech sensor pressure; Device
Lead sponsor: Microtech Medical Technologies, Ltd; Industry
Eligibility: Not listed
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Chest Pain, Myocardial Ischemia, Heart Disease, Coronary Arterial Disease (CAD), Angina
Interventions: Cell Therapy - Autologous CD34 Positive Cells; Genetic
Lead sponsor: Losordo, Douglas, M.D.; Individual
Eligibility: 21 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2006
U.S. locations: 3
States / cities: La Jolla, California • Boston, Massachusetts • Minneapolis, Minnesota

Conditions: Acute Myocardial Infarction
Interventions: Post conditioning, Usual Care for STEMI; Procedure
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2008
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Type 2 Diabetes, Obesity
Interventions: Exercise; Behavioral
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 30 Years to 80 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 3
States / cities: New Brunswick, New Jersey

Conditions: Heart Disease, Atrial Fibrillation
Interventions: Not listed
Lead sponsor: Emile Daoud; Other
Eligibility: 18 Years and older · Female only
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: End-Stage Heart Failure, Bridge-to-Transplant LVAD Placement (BTT), Destination Therapy LVAD Placement (DT), Refusal of LVAD Placement (Decliners), LVAD Caregivers
Interventions: LVAD Decision Aid; Other
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 30 Years to 85 Years
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 7
States / cities: New Orleans, Louisiana • Cleveland, Ohio • Oklahoma City, Oklahoma + 2 more

Conditions: Coronary Angiography, Coronary Angioplasty
Interventions: Distal radial artery access, Proximal radial artery surgery; Procedure
Lead sponsor: Baylor Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Plano, Texas

Conditions: Heart Arrest
Interventions: Impedance Threshold Device (ITD), Sham ITD, Analyze early, Analyze later; Device · Other
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 11,738 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 7
States / cities: Birmingham, Alabama • San Diego, California • Portland, Oregon + 4 more

Search by objective public record fields.

Evaluate Effect of Optison on Pulmonary Artery Systolic Pressure (PASP) and Pulmonary Vascular Resistance (PVR).

PARTNER II Trial: S3iCAP

Assessing the Neurological Outcomes After Atrial Fibrillation Ablation for Rhythm Control

Transient Receptor Potential Vanilloid One (TRPV1) Receptor Expression in Children With Retrosternal Pain

Early Feasibility Study of 3830 Lead Implantation Via the Middle Cardiac Vein in Patients With Prior or Planned Tricuspid Valve Intervention

Mitochondrial Dysfunction Contributes to Sepsis Induced Cardiac Dysfunction

A SkeleTal Muscle Recovery Intervention With Dietary Protein in Heart Failure

Outcomes and Safety Trial Investigating Ecallantide's Effect on Reducing Surgical Blood Loss Volume in Subjects at High Risk of Bleeding Exposed to Cardio-pulmonary Bypass During Cardiac Surgery

Digital Monitoring for Patients Post Coronary Interventions to Reduce Risk for Recurrent Adverse Cardiovascular Events

Provider Notification for High B-type Natriuretic Peptide Values

Belatacept in Heart Transplantation

Real World Effectiveness of the Cordella Pulmonary Artery Sensor System in Patients With Chronic Heart Heart Failure

Using Tissue Doppler/Synchronization to Determine Heart Function in Children With Congenital Heart Disease

Mechanisms of Vasovagal Syncope

Human Brain Natriuretic Peptide (BNP) (or Nesiritide) to Help Heart, Kidney and Humoral Function.

Effects of Face Masks During Exercise

Assessment of Safety and Accuracy of the Microtech System in Patients Undergoing Left Ventricular Assist Device Implantation

Stem Cell Study for Patients With Heart Disease

Minimizing Reperfusion Injury in Patients With Acute Myocardial Infarction

Extracellular Vesicles, Insulin Action, and Exercise

Data Collection and Analysis of Patients Who Have Had an Electrophysiological Procedure

Development & Testing of a Decision Aid for LVAD Placement

DIstal vs Proximal Radial Artery Access for Cath

Resuscitation Outcomes Consortium (ROC) Prehospital Resuscitation Using an Impedance Valve