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ClinicalTrials.gov public records Last synced Nov 3, 2026, 4:52 PM EST

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Showing 25–48 of 9,533 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: HEARTS Clear all
Completed Not applicable Interventional Results available

Exercise Training in Heart Failure: Changes in Cardiac Structure and Function

NCT02275819
View directory record Official record
Conditions
Heart Failure
Interventions
Exercise
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 8, 2021 · Synced Nov 3, 2026, 4:52 PM EST
Completed Not applicable Interventional Results available

Suture Closure AFtEr VEIN Access for Cardiac Procedures (SAFE-VEIN) Trial

NCT04632641
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter, Heart Block, Pulmonary Embolism and Thrombosis, Mitral Valve Repair, Sinus Node Dysfunction, Bradycardia, Brady-tachy Syndrome
Interventions
Perclose ProGlide Suture-Mediated Closure System (SMC) - LARGE-BORE PROCEDURES, Figure 8 Suture - LARGE-BORE PROCEDURES
Device · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Nov 3, 2026, 4:52 PM EST
Not listed No phase listed Observational

Long Term Evaluation of Cardiac Arrhythmias After Transcatheter Aortic Valve Implantation -The LOCATE Registry

NCT06055751
View directory record Official record
Conditions
Aortic Stenosis, Atrial Fibrillation New Onset, Heart Block
Interventions
TAVR Procedure and implantation of Boston Scientific Loop Recorder (LUX-Dx PMA# K193473)
Device
Lead sponsor
Kansas City Heart Rhythm Research Foundation
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Nov 3, 2026, 4:52 PM EST
Completed No phase listed Observational Accepts healthy volunteers

Transverse Thoracic Plane Block in the Pediatric Cardiac Patient

NCT04138745
View directory record Official record
Conditions
Pain, Acute, Congenital Heart Disease
Interventions
Transverse Thoracic Plane Block
Other
Lead sponsor
Ochsner Health System
Other
Eligibility
0 Years to 18 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 9, 2021 · Synced Nov 3, 2026, 4:52 PM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Atrial Fibrillation Algorithms Clinical Validation Study

NCT04699812
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
ELECTROCARDIOGRAM (ECG) PATCH WEAR
Device
Lead sponsor
Apple Inc.
Industry
Eligibility
22 Years and older
Enrollment
573 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
4
States / cities
Coral Gables, Florida • Avon, Indiana • Wichita, Kansas + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 24, 2022 · Synced Nov 3, 2026, 4:52 PM EST
Recruiting Phase 1 Interventional

Emapalumab With Post-Transplant Cyclophosphamide, Tacrolimus and Mycophenolate Mofetil for the Prevention of Graft-versus-Host Disease After Donor Reduced-Intensity Hematopoietic Cell Transplant

NCT06996119
View directory record Official record
Conditions
Acute Myeloid Leukemia, Graft Versus Host Disease, Myelodysplastic Syndrome
Interventions
Biospecimen Collection, Busulfan, Computed Tomography, Cyclophosphamide, Echocardiography Test, Emapalumab, Fludarabine, Hematopoietic Cell Transplantation, Melphalan, Multigated Acquisition Scan, Mycophenolate Mofetil, Questionnaire Administration, Tacrolimus
Procedure · Drug · Biological + 1 more
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Nov 3, 2026, 4:52 PM EST
Recruiting Phase 4 Interventional

Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical Study

NCT05030545
View directory record Official record
Conditions
Primary Aldosteronism, Hypertension
Interventions
Eplerenone
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Nov 3, 2026, 4:52 PM EST
Completed Phase 4 Interventional Results available

Sternal Block With Liposomal Bupivacaine vs. Saline Prior to Incision in Cardiac Surgery

NCT04333095
View directory record Official record
Conditions
Cardiovascular Surgery, Pain, Postoperative, Block
Interventions
Liposomal bupivacaine, Normal Saline Flush, 0.9% Injectable Solution_#1
Drug
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Nov 3, 2026, 4:52 PM EST
Completed Not applicable Interventional Results available

Comparison of Orbital Versus Rotational Atherectomy Effects On Coronary Microcirculation in PCI

NCT03021577
View directory record Official record
Conditions
Coronary Artery Disease (CAD)
Interventions
Orbital Atherectomy System (OAS), Rotablator Rotational Atherectomy System, Magnetic Resonance Imaging (MRI)
Device · Procedure
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Nov 3, 2026, 4:52 PM EST
Completed Not applicable Interventional

Chronic Effects of Freeze-Dried Strawberry Beverage on Cardiovascular Risk Factors

NCT01883401
View directory record Official record
Conditions
Dyslipidemia, Obesity
Interventions
Freeze-dried strawberries, Dietary fiber
Dietary Supplement
Lead sponsor
Oklahoma State University
Other
Eligibility
19 Years to 72 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Stillwater, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 21, 2013 · Synced Nov 3, 2026, 4:52 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Using Feedback Reports to Improve Medication Adherence

NCT02480530
View directory record Official record
Conditions
Coronary Artery Disease, Adherence
Interventions
Individual Feedback, Feedback Friend
Behavioral
Lead sponsor
Corporal Michael J. Crescenz VA Medical Center
Federal
Eligibility
30 Years to 75 Years
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 30, 2018 · Synced Nov 3, 2026, 4:52 PM EST
Completed No phase listed Observational

Assessment of Dual AntiPlatelet Therapy With Drug Eluting Stents

NCT00638794
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Drug -Eluting Stent (Taxus™, Cypher®, Endeavor™, Xience V™)
Device
Lead sponsor
Cardiovascular Research Foundation, New York
Other
Eligibility
18 Years and older
Enrollment
8,575 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
8
States / cities
Minneapolis, Minnesota • New York, New York • Charlotte, North Carolina + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 23, 2013 · Synced Nov 3, 2026, 4:52 PM EST
Withdrawn Phase 4 Interventional

Rejuvenated, Washed Packed Red Blood Cells in Pediatric Cardiac Surgery

NCT02485366
View directory record Official record
Conditions
Heart Defects, Congenital
Interventions
Rejuvesol, Cardiac surgery
Drug · Procedure
Lead sponsor
Duke University
Other
Eligibility
Up to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 27, 2020 · Synced Nov 3, 2026, 4:52 PM EST
Not listed Phase 2Phase 3 Interventional

To Assess Safety and Efficacy of Myoblast Implantation Into Myocardium Post Myocardial Infarction

NCT00526253
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
MyoCell, Hypothermosol
Biological · Procedure
Lead sponsor
Bioheart, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
33
States / cities
Birmingham, Alabama • Gilbert, Arizona • Phoenix, Arizona + 25 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2017 · Synced Nov 3, 2026, 4:52 PM EST
Terminated Not applicable Interventional Results available

Remote Preconditioning Over Time To Empower Cerebral Tissue

NCT02169739
View directory record Official record
Conditions
Ischemic Stroke, Cerebral Small Vessel Disease, Cognitive Decline
Interventions
Ischemic Preconditioning
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
40 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 10, 2021 · Synced Nov 3, 2026, 4:52 PM EST
Not listed Not applicable Interventional Accepts healthy volunteers

ENRICH Nurse-Family Partnership Study

NCT05798039
View directory record Official record
Conditions
Blood Pressure, Body Composition, Blood Sugar, Body Weight, Diet Habit, Physical Inactivity
Interventions
ENRICH
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 18, 2024 · Synced Nov 3, 2026, 4:52 PM EST
Terminated Phase 1 Interventional

Study of Low Dose Nesiritide With or Without Sildenafil in Congestive Heart Failure Patients With Renal Dysfunction

NCT00818701
View directory record Official record
Conditions
Congestive Heart Failure, Renal Dysfunction
Interventions
low dose Nesiritide, nesiritide, Sildenafil
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 24, 2010 · Synced Nov 3, 2026, 4:52 PM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Coronary Atherosclerosis T1-Weighted Characterization (CATCH)

NCT03504956
View directory record Official record
Conditions
Coronary Atherosclerosis
Interventions
Cardiac MRI, Contrast, Beta blocker
Device · Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Nov 3, 2026, 4:52 PM EST
Completed Phase 1Phase 2 Interventional Results available

Anesthetics to Prevent Lung Injury in Cardiac Surgery

NCT02918877
View directory record Official record
Conditions
Inflammatory Lung Injury, Ischemia-Reperfusion Lung Injury, Postoperative Pulmonary Complications
Interventions
Sevoflurane, Propofol
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 5, 2021 · Synced Nov 3, 2026, 4:52 PM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Does Style Matter: Comparison of Moderate- to Low-intensity Styles of Yoga

NCT07638267
View directory record Official record
Conditions
Insomnia, Health Adult Subjects, Insomnia Disorder, Heart Health Markers
Interventions
Vinyasa yoga, Gentle yoga, Non-active control
Behavioral · Other
Lead sponsor
Caitlin Cheruka
Other
Eligibility
18 Years to 40 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Nov 3, 2026, 4:52 PM EST
Completed No phase listed Observational

Understanding the Genetic and Hereditary Basis of Atherosclerosis

NCT00344292
View directory record Official record
Conditions
Atherosclerosis, Cardiovascular Diseases
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
15 Years to 34 Years
Enrollment
2,763 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
4
States / cities
Los Angeles, California • New Orleans, Louisiana • Houston, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 8, 2017 · Synced Nov 3, 2026, 4:52 PM EST
Recruiting Phase 1Phase 2 Interventional

CMVIG Prophylaxis in Belatacept Conversion Kidney Transplant Recipients

NCT07096453
View directory record Official record
Conditions
Kidney Transplant; Complications, CMV
Interventions
Cytogam
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Nov 3, 2026, 4:52 PM EST
Completed No phase listed Observational

Safe Emergency Department DIscharGE Rate (SEIGE)

NCT04772157
View directory record Official record
Conditions
Acute Myocardial Infarction, Acute Coronary Syndrome
Interventions
Cardiac Troponin Testing
Diagnostic Test
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
21 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 17, 2024 · Synced Nov 3, 2026, 4:52 PM EST
Withdrawn Not applicable Interventional

Use of NGAL for Fluid Dosing and CRRT Initiation in Pediatric and Neonatal AKI

NCT05114057
View directory record Official record
Conditions
Acute Kidney Injury, Acute Kidney Injury Due to Sepsis, Neonatal Sepsis
Interventions
Renal Angina Index (RAI)
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Up to 25 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Nov 3, 2026, 4:52 PM EST