Independent directory Public ClinicalTrials.gov records United States
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Showing 73–96 of 9,538 matching trials from the live ClinicalTrials.gov search.
Conditions
Heart Defects, Congenital, Heart Failure, Congestive
Interventions
Enalapril, Placebo
Drug
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
Up to 45 Days
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
8
States / cities
Boston, Massachusetts • New York, New York • Durham, North Carolina + 5 more
Completed No phase listed Observational Accepts healthy volunteers

Effect of Testosterone Treatment on Drug Metabolism and Transport

NCT05116293
Conditions
Transgender Persons
Interventions
Midazolam oral solution, Digoxin Oral Tablet, Acetaminophen Oral Tablet
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 60 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Congenital Heart Disease
Interventions
Not listed
Lead sponsor
Drexel University
Other
Eligibility
1 Hour to 19 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Active, not recruiting Not applicable Interventional

Senior Adult Hepatobiliary Prehab Study

NCT05921552
Conditions
Hepatobiliary Cancer, Cholangiocarcinoma, Liver Metastases
Interventions
Resistance Training, Aerobic Training
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
65 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Not listed No phase listed Observational

Cardiometabolic Risk in Cardiac Rehab

NCT01985048
Conditions
Coronary Artery Disease
Interventions
Not listed
Lead sponsor
Health Diagnostic Laboratory, Inc.
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
3
States / cities
Camp Hill, Pennsylvania • Ephrata, Pennsylvania • Lancaster, Pennsylvania
Conditions
Atrial Fibrillation
Interventions
Electrocardiogram
Diagnostic Test
Lead sponsor
Fitbit LLC
Industry
Eligibility
22 Years and older
Enrollment
472 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
9
States / cities
Washington D.C., District of Columbia • Orlando, Florida • The Villages, Florida + 6 more
Enrolling by invitation No phase listed Observational

Developing MRI Technologies for Atrial Fibrillation

NCT07083115
Conditions
Atrial Fibrillation (AF)
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Meditation, Cognitive Reappraisal, Emotional Regulation
Interventions
Inner Engineering Program
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
15 Years to 18 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Mitral Valve Insufficiency, Heart Failure
Interventions
Surgical mitral valvuloplasty with placement of annular ring (SMVR), Optimal medical therapy (OMT)
Procedure · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
8
States / cities
Atlanta, Georgia • Boston, Massachusetts • Minneapolis, Minnesota + 5 more
Conditions
Lennox-Gastaut Syndrome, Dravet Syndrome
Interventions
12-Lead ECG, Cannabidiol
Procedure · Drug
Lead sponsor
Gillette Children's Specialty Healthcare
Other
Eligibility
2 Years to 30 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Saint Paul, Minnesota
Conditions
Obesity
Interventions
Fitbit Charge HR plus weekly phone calls to review physical activity data
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
7 Years to 18 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Arrhythmogenic Cardiomyopathy, PKP2-ACM, PKP2-ARVC
Interventions
Not listed
Lead sponsor
Lexeo Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
6
States / cities
Redwood City, California • Baltimore, Maryland • Columbia, Maryland + 3 more
Conditions
Adult Rhabdomyosarcoma, Lung Metastases, Metastatic Ewing Sarcoma, Previously Treated Childhood Rhabdomyosarcoma, Recurrent Adult Soft Tissue Sarcoma, Recurrent Childhood Rhabdomyosarcoma, Recurrent Wilms Tumor and Other Childhood Kidney Tumors, Stage IV Adult Soft Tissue Sarcoma, Stage IV Wilms Tumor, Stage V Wilms Tumor, Unspecified Adult Solid Tumor, Protocol Specific, Unspecified Childhood Solid Tumor, Protocol Specific
Interventions
intensity-modulated radiation therapy
Radiation
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
1 Year to 29 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
7
States / cities
Atlanta, Georgia • Chicago, Illinois • Indianapolis, Indiana + 4 more
Completed Not applicable Interventional Results available

Exercise in Adults With Mild Memory Problems

NCT02814526
Conditions
Mild Cognitive Impairment, Cognitive Decline, Memory Impairment
Interventions
Aerobic exercise, Stretching/balance/range of motion exercise
Behavioral
Lead sponsor
Alzheimer's Disease Cooperative Study (ADCS)
Other
Eligibility
65 Years to 89 Years
Enrollment
296 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
14
States / cities
Irvine, California • Palo Alto, California • New Haven, Connecticut + 10 more
Completed Not applicable Interventional Results available

On-pump Intraoperative Echocardiography

NCT03094325
Conditions
Septal Myectomy
Interventions
Pre Operative On-pump intraoperative echocardiography, Pre Operative Transesophageal echocardiography (TEE) imaging, Post Operative On-pump intraoperative echocardiography, Post Operative Transesophageal echocardiography (TEE) imaging
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Not listed Not applicable Interventional Accepts healthy volunteers

WHISH-2-Prevent Heart Failure

NCT03099889
Conditions
Physical Activity, Heart Failure, Heart Failure With Reduced Ejection Fraction, Heart Failure With Normal Ejection Fraction, Strength Training, Elderly, Women
Interventions
Physical Activity
Behavioral
Lead sponsor
Memorial Hospital of Rhode Island
Other
Eligibility
66 Years to 102 Years · Female only
Enrollment
49,936 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
Pawtucket, Rhode Island
Conditions
Coronary Stenosis
Interventions
Ringer Perfusion Balloon Catheter
Device
Lead sponsor
Vascular Solutions LLC
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
4
States / cities
Torrance, California • Boston, Massachusetts • Kansas City, Missouri + 1 more
Conditions
Off Pump Coronary Artery Bypass Surgery
Interventions
Vacuum Stabilizer System, Vacuum Positioner System, Blower/Mister, Proximal Seal System
Device
Lead sponsor
Maquet Cardiovascular
Industry
Eligibility
22 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Stockton, California • Wausau, Wisconsin
Conditions
Coronary Artery Disease
Interventions
Ticagrelor 180mg, Ticagrelor 90mg
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Jacksonville, Florida
Conditions
Heart Failure
Interventions
Not listed
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Houston, Texas
Conditions
Phenylketonuria, PKU
Interventions
Acute Moderate Intensity Exercise
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
14 Years to 17 Years · Male only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Congenital Heart Disease, Single Ventricle, Myocardial Fibrosis
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 90 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Coronavirus Infection, COVID, Covid-19, SARS-CoV-2
Interventions
Point-of-Care Ultrasonography (POCUS)
Diagnostic Test
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
2
States / cities
Minneapolis, Minnesota • Saint Paul, Minnesota
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Fetal Aortic Valvuloplasty for Evolving Hypoplastic Left Heart Syndrome

NCT06342999
Conditions
Hypoplastic Left Heart Syndrome
Interventions
Fetal Aortic Valvuloplasty Procedure, Emerge Monorail and Over-The-Wire PTCA Dilatation Catheter, Trek RX and Mini Trek RX Coronary Dilatation Catheter
Procedure · Device
Lead sponsor
Mauro H. Schenone
Other
Eligibility
Up to 45 Years · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2036
U.S. locations
1
States / cities
Rochester, Minnesota