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Showing 1–21 of 21 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: HEPA Air Cleaner Clear all
Recruiting Not applicable Interventional

The Airports, Air Quality, and Asthma (AAA) Study

NCT07047430
View directory record Official record
Conditions
Pediatric Asthma
Interventions
Portable air cleaner with HEPA filter, Less effective portable air cleaner (no HEPA)
Device
Lead sponsor
University of Washington
Other
Eligibility
6 Years to 12 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 1, 2025 · Synced Sep 10, 2026, 4:38 AM EDT
Completed Not applicable Interventional

Home Air in Agriculture: Pediatric Intervention Trial

NCT04919915
View directory record Official record
Conditions
Asthma in Children
Interventions
HEPA air cleaner
Device
Lead sponsor
University of Washington
Other
Eligibility
6 Years to 12 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Yakima, Washington
Source: ClinicalTrials.gov public record
Updated Jun 8, 2021 · Synced Sep 10, 2026, 4:38 AM EDT
Completed Not applicable Interventional Results available

Effects of Reducing Indoor Air Pollution on the Adult Asthmatic Response

NCT02153359
View directory record Official record
Conditions
Asthma
Interventions
High Efficiency Particulate Air Cleaner, Sham air cleaner
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 50 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 11, 2019 · Synced Sep 10, 2026, 4:38 AM EDT
Completed Phase 3 Interventional

Particulate Reduction Education in City Homes

NCT00466024
View directory record Official record
Conditions
Asthma
Interventions
Health Coach and HEPA air cleaners
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
6 Years to 12 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 31, 2015 · Synced Sep 10, 2026, 4:38 AM EDT
Completed Not applicable Interventional

Durham Healthy Breathing in Healthy Homes Project

NCT04119271
View directory record Official record
Conditions
Poor Asthma Control
Interventions
Breathe Easy at Home Kit Products
Other
Lead sponsor
Duke University
Other
Eligibility
5 Years to 16 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 3, 2023 · Synced Sep 10, 2026, 4:38 AM EDT
Recruiting Not applicable Interventional

The Allergen Reduction and Child Health Study (ARCHS)

NCT04331353
View directory record Official record
Conditions
Asthma in Children
Interventions
Comparator 1 (tailored approach), Comparator 2 (insecticidal bait)
Behavioral
Lead sponsor
Tulane University
Other
Eligibility
5 Years to 17 Years
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Sep 10, 2026, 4:38 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

School Inner City Air Study

NCT05953233
View directory record Official record
Conditions
Viral Infection
Interventions
Active classroom HEPA cleaner, Sham classroom HEPA cleaner
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
6 Years to 90 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Sep 10, 2026, 4:38 AM EDT
Active, not recruiting Not applicable Interventional

Air Filtration for COPD in VA Population of Veterans

NCT05913765
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Air cleaner
Device
Lead sponsor
Illinois Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 22, 2024 · Synced Sep 10, 2026, 4:38 AM EDT
Active, not recruiting Not applicable Interventional

AIRWEIGHS: Investigating Obesity as a Susceptibility Factor for Air Pollution in Childhood Asthma

NCT02763917
View directory record Official record
Conditions
Asthma
Interventions
Active Air Purifier, Placebo Air Purifier
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
8 Years to 17 Years
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Sep 10, 2026, 4:38 AM EDT
Not yet recruiting Phase 4 Interventional

The INTERvening for LUNG Health Trial

NCT07540000
View directory record Official record
Conditions
Spirometry
Interventions
Community health worker-delivered multi-component respiratory health intervention
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
9 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 10, 2026, 4:38 AM EDT
Recruiting Phase 3 Interventional

Multi-Center Clean Air Randomized Controlled Trial in COPD

NCT06376994
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Air cleaner, Sham air cleaner
Device
Lead sponsor
JHSPH Center for Clinical Trials
Other
Eligibility
40 Years and older
Enrollment
770 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
11
States / cities
Birmingham, Alabama • Los Angeles, California • Iowa City, Iowa + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 10, 2026, 4:38 AM EDT
Recruiting Not applicable Interventional

Cost Effective Air Filtration Intervention in Low-Income Housing to Reduce Asthma Morbidity

NCT07116460
View directory record Official record
Conditions
Asthma Attack, Lung Function, Airway Inflammation
Interventions
Austin Air Cleaner
Device
Lead sponsor
Columbia University
Other
Eligibility
7 Years to 18 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 10, 2026, 4:38 AM EDT
Recruiting Not applicable Interventional

Asthma Intervention With Residential Ventilation and Air Cleaner (AIRVAC) Study

NCT07196436
View directory record Official record
Conditions
Asthma Control, Pulmonary Function, Quality of Life, Stress, Sleep Quality
Interventions
Energy Recovery Ventilator, Portable Air Cleaner, Energy Recovery Ventilator (Sham), Portable Air Cleaner (Sham)
Device
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
5 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Arlington, Texas • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Sep 10, 2026, 4:38 AM EDT
Completed Not applicable Interventional Results available

Motivational Interviewing and Air Cleaners for Smokers With COPD (MOVE COPD)

NCT03658538
View directory record Official record
Conditions
COPD, Chronic Obstructive Pulmonary Disease
Interventions
Active HEPA Air Cleaner, Motivational interviewing, Sham Air Cleaner
Device · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
40 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Sep 10, 2026, 4:38 AM EDT
Completed Not applicable Interventional

The Duke-Reinvestment Partners Community Collaborative (DRC)- Healthy Homes

NCT05934370
View directory record Official record
Conditions
Asthma in Children
Interventions
Home-Based Environmental Interventions (HEI)
Other
Lead sponsor
Duke University
Other
Eligibility
4 Years to 16 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Sep 10, 2026, 4:38 AM EDT
Completed Not applicable Interventional Results available

Cleaner Air for Better Cardiac Biomarkers

NCT05379400
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Portable air cleaner (PAC), Sham Portable air cleaner (PAC)
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Sep 10, 2026, 4:38 AM EDT
Completed Not applicable Interventional

Cleaner Air for Lower Cardiometabolic Risk

NCT05994937
View directory record Official record
Conditions
PreDiabetes
Interventions
PAC with HEPA filter intact, PAC with HEPA filter removed
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 10, 2026, 4:38 AM EDT
Recruiting Not applicable Interventional

Project 4: ACHIEVE PATHFINDER

NCT06070428
View directory record Official record
Conditions
Heart Failure
Interventions
PAC provision at hospital discharge, Control non-intervention; PAC without filter
Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 10, 2026, 4:38 AM EDT
Completed Not applicable Interventional

Clinical Trial of Air Cleaners to Improve Indoor Air Quality and COPD Health

NCT02236858
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
HEPA Air Cleaner, Sham HEPA Air Cleaner
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
40 Years and older
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 13, 2021 · Synced Sep 10, 2026, 4:38 AM EDT
Recruiting Not applicable Interventional

Reducing AIR Pollution Exposure to Lower Blood PRESSURE Among New York City Public Housing Residents

NCT05874479
View directory record Official record
Conditions
Blood Pressure
Interventions
Active PAC, Sham PAC
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 10, 2026, 4:38 AM EDT
Completed Not applicable Interventional

A Community-based Participatory Research (CBPR) Intervention for Childhood Asthma Using Air Filters and Air Conditioners

NCT00839046
View directory record Official record
Conditions
Childhood Asthma
Interventions
Community Health Worker Intervention, Air Filter, Air Filter and Air Conditioner
Behavioral · Other
Lead sponsor
University of Michigan
Other
Eligibility
6 Years to 12 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 23, 2017 · Synced Sep 10, 2026, 4:38 AM EDT