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ClinicalTrials.gov public records Last synced Oct 2, 2026, 11:22 AM EDT

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Showing 49–72 of 188 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: HIV Prevention Information Clear all
Completed Not applicable Interventional Accepts healthy volunteers

The OPENS Trial: Offering Women PrEP (Aim 2)

NCT05619497
View directory record Official record
Conditions
Human Immunodeficiency Virus, Human Immunodeficiency Virus Transmission, Sexually Transmitted Diseases
Interventions
Clinic-wide Trainings, Clinic-wide Trainings and HIV Prevention Decision Support Tool (DST), Standard Care with the HIV Prevention Decision Support Tool (DST)
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 45 Years
Enrollment
141 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Oct 2, 2026, 11:22 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Five Point Initiative: A Bundled Implementation Strategy to Address the HIV Epidemic in Black Communities

NCT06062342
View directory record Official record
Conditions
Hiv
Interventions
FPI
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
20,400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 2, 2026, 11:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving Health Outcomes in Young Cisgender Men and Transgender Women (mLab App)

NCT03803683
View directory record Official record
Conditions
HIV Infections
Interventions
mLab App, HIV Prevention Information, HIV Home Tests
Device · Behavioral
Lead sponsor
Rebecca Schnall, RN, MPH, PhD
Other
Eligibility
18 Years to 29 Years · Male only
Enrollment
525 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
Chicago, Illinois • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Oct 2, 2026, 11:22 AM EDT
Recruiting Not applicable Interventional

WePrEP: Developing a PrEP Shared Decision-making Tool for Transgender Women

NCT06656676
View directory record Official record
Conditions
HIV Prevention
Interventions
WePrEP: A shared decision-making tool, Active comparator: CDC recommendations for discussing PrEP
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Sheridan, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Oct 2, 2026, 11:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Pragmatic Trial of Two Strategies for Implementing an Effective eHealth HIV Prevention Program (Keep It Up! 3.0)

NCT03896776
View directory record Official record
Conditions
HIV/AIDS, Gonorrhea, Chlamydia
Interventions
Keep It Up! 3.0
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 34 Years · Male only
Enrollment
2,125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 7, 2023 · Synced Oct 2, 2026, 11:22 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

MyPEEPS Mobile Plus: A Multi-Level HIV Prevention Intervention for Young MSM

NCT06741618
View directory record Official record
Conditions
HIV/AIDS
Interventions
MyPEEPS Mobile, Electronic PrEP peer navigation
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
16 Years to 25 Years · Male only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 2, 2026, 11:22 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

A Multilevel, Multiphase Optimization Strategy for PrEP (MOST:PrEP)

NCT06334341
View directory record Official record
Conditions
HIV Seropositivity
Interventions
Computer-based simulation training for providers, Best Practice Alert, HIV Risk Assessment, PrEP Informational Video
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
1,380 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 2, 2026, 11:22 AM EDT
Completed Not applicable Interventional

HIV Prevention and Trauma Treatment in Men Who Have Sex With Men and Who Have a History of Sexual Abuse

NCT00797654
View directory record Official record
Conditions
Risk Reduction
Interventions
Information-motivation-behavior skills and cognitive processing therapy, Pre and Post HIV-Test Counseling
Behavioral
Lead sponsor
Fenway Community Health
Other
Eligibility
18 Years and older · Male only
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 9, 2016 · Synced Oct 2, 2026, 11:22 AM EDT
Recruiting Not applicable Interventional

PrEP and MOUD Rapid Access for Persons Who Inject Drugs: The CHORUS+ Study

NCT05769218
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
CHORUS+, Standard of care
Behavioral · Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
284 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 2, 2026, 11:22 AM EDT
Recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Naltrexone for Overdose Prevention

NCT06633900
View directory record Official record
Conditions
Overdose Accidental
Interventions
IM naltrexone, Usual Care
Drug · Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 2, 2026, 11:22 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Using PrEP, Doing It for Ourselves

NCT06638892
View directory record Official record
Conditions
HIV Prevention, PrEP
Interventions
Using PrEP, Doing it for Ourselves (UPDOs), Standard of Care
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 2, 2026, 11:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Harnessing the Power of Text Messaging to Invigorate AMSM HIV Preventive Behavior

NCT02113956
View directory record Official record
Conditions
HIV
Interventions
Guy2Guy (G2G)
Behavioral
Lead sponsor
Center for Innovative Public Health Research
Other
Eligibility
14 Years to 18 Years · Male only
Enrollment
302 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
2
States / cities
San Clemente, California • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 10, 2020 · Synced Oct 2, 2026, 11:22 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Test-to-PrEP Study

NCT06927856
View directory record Official record
Conditions
HIV Infections
Interventions
Test-to-PrEP, Access by Referral
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 2, 2026, 11:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Testing a Behavioral Intervention to Incorporate Advances in HIV Prevention for Black Young MSM in Alabama

NCT03680729
View directory record Official record
Conditions
HIV/AIDS
Interventions
Adapted Brothers Saving Brothers (aBSB), Standard Street Outreach
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 99 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 2, 2026, 11:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

ANCHORS Study: UH2 Project

NCT03360422
View directory record Official record
Conditions
HIV-1-infection
Interventions
Survey, Focus Group, Usability study
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
673 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 11, 2024 · Synced Oct 2, 2026, 11:22 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sexual Health Advocacy for Guys - a Text Messaging-based HIV Prevention Program for Guys Who Are Into Guys

NCT06230367
View directory record Official record
Conditions
HIV Infections
Interventions
Sexual health advocacy for guys, Healthy lifestyle control
Behavioral
Lead sponsor
Center for Innovative Public Health Research
Other
Eligibility
13 Years to 22 Years · Male only
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
2
States / cities
San Clemente, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 2, 2026, 11:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Online Network Intervention to Increase HIV Pre-exposure Prophylaxis Intention

NCT04771312
View directory record Official record
Conditions
Behavior, Health
Interventions
Mobile app information-only intervention, Mobile app social support network intervention
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Oct 1, 2021 · Synced Oct 2, 2026, 11:22 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Getting to Zero Among HHI MSM in the American South

NCT05075967
View directory record Official record
Conditions
HIV Infections
Interventions
Health Access Coalitions, Social Media, Peer Support, Promoting Human Autonomy Support & Empathy (PHASE)
Behavioral
Lead sponsor
HIV Prevention Trials Network
Network
Eligibility
15 Years and older · Male only
Enrollment
2,700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 2, 2026, 11:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving the Reproductive Health of Families

NCT03858803
View directory record Official record
Conditions
Reproductive Health
Interventions
Families Matter 2, Living as a Safer Teen
Behavioral
Lead sponsor
Portland State University
Other
Eligibility
13 Years to 80 Years
Enrollment
945 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 17, 2025 · Synced Oct 2, 2026, 11:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

eSTEP: An Integrated mHealth Intervention to Engage High-risk Individuals Along the Full PrEP Care Continuum

NCT06159582
View directory record Official record
Conditions
Pre-Exposure Prophylaxis (PrEP)
Interventions
eSTEP, Usual Care
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
18 Years and older · Male only
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 2, 2026, 11:22 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Academic Detailing to Optimize PrEP Implementation in Pediatric Primary Care Settings: ADOPT-PrEP

NCT06804382
View directory record Official record
Conditions
PrEP, HIV Prevention Program
Interventions
Academic detailing
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Oct 2, 2026, 11:22 AM EDT
Completed Not applicable Interventional

Behavioral Activation, Nutrition, and Activity Intervention

NCT06239961
View directory record Official record
Conditions
HIV
Interventions
Social Connection, Nutritional Coaching, Physical Activity Coaching
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
50 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 4, 2025 · Synced Oct 2, 2026, 11:22 AM EDT
Completed Not applicable Interventional

Primary Care-Based Interventions to Reduce Alcohol Use Among HIV Patients

NCT01671501
View directory record Official record
Conditions
HIV, Acquired Immunodeficiency Syndrome, Alcoholism, Alcoholic Intoxication, Substance-Related Disorders
Interventions
Motivational Interviewing, Email Feedback, Usual Care
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 100 Years
Enrollment
614 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 10, 2018 · Synced Oct 2, 2026, 11:22 AM EDT
Completed Phase 2 Interventional

Reducing Sex-Related HIV Risk Behaviors in Patients Receiving Treatment for Opioid Dependence

NCT00548275
View directory record Official record
Conditions
Opiate Dependence, HIV Infections
Interventions
Enhanced Sexual Risk Management, Standard Sexual Risk Management
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 3, 2020 · Synced Oct 2, 2026, 11:22 AM EDT