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Showing 1–24 of 108 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: HIV and STI testing Clear all
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Implementation and Deliver of Lenacapavir for PrEP in a Community Pharmacy Setting

NCT07210125
View directory record Official record
Conditions
HIV
Interventions
Lenacapavir long-acting, Standard of Care (SOC)
Drug · Other
Lead sponsor
Kelley-Ross & Associates, Inc.
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Sep 2, 2026, 7:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Game Plan: Efficacy of a Brief, Web-based Intervention on Alcohol Use and Sexually-transmitted Infections

NCT04552171
View directory record Official record
Conditions
Sexually Transmitted Diseases, Bacterial, Alcohol; Harmful Use
Interventions
Access to Game Plan app and 24-hour helpline
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Male only
Enrollment
314 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 2, 2026, 7:10 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

WHC+ (Women's Health CoOp PLUS)

NCT01497405
View directory record Official record
Conditions
HIV, Sexual Risk, Sexually Transmitted Diseases, Substance Abuse, Violence, Victimization
Interventions
Test, Treat, Retain(TTR) + Women's Health CoOp (WHC), Test, Treat, Retain(TTR) only
Behavioral · Biological
Lead sponsor
RTI International
Other
Eligibility
15 Years to 55 Years · Female only
Enrollment
641 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Sep 2, 2026, 7:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Partner Services Pre-exposure Prophylaxis (PS-PrEP)

NCT02749955
View directory record Official record
Conditions
HIV Transmission, Transtheoretical Model of Change
Interventions
PS-PrEP Intervention Group, PrEPLine Control Group
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
164 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Sep 2, 2026, 7:10 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating the Effectiveness of a Mobile HIV Prevention App to Increase HIV and Sexually Transmitted Infections (STI) Testing and PrEP Initiation Among Rural Men Who Have Sex With Men

NCT06205368
View directory record Official record
Conditions
HIV Infections, STI, HIV Pre-exposure Prophylaxis
Interventions
Combine mobile app, Motivational interview, HIV/STI testing
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 45 Years · Male only
Enrollment
473 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Sep 2, 2026, 7:10 AM EDT
Completed Not applicable Interventional

Stigma and Online Counseling to Increase HIV/STI Testing

NCT03107910
View directory record Official record
Conditions
HIV/STI Testing
Interventions
Stigma and Structural Interventions, Health Information Seeking
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years and older · Male only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 29, 2021 · Synced Sep 2, 2026, 7:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preventing HIV/STI in Urban Adolescents Via an mHealth Primary Care Intervention

NCT03368456
View directory record Official record
Conditions
HIV/AIDS and Infections, Drug Abuse, Adolescent Behavior, Drug Usage
Interventions
S4E, Usual Care
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 21 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Ypsilanti, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 30, 2022 · Synced Sep 2, 2026, 7:10 AM EDT
Not yet recruiting Not applicable Interventional

Implementation of an Opt-Out Testing and Rapid Diagnostic Strategy for Syphilis and HIV in Pregnant Patients Presenting to the Emergency Department

NCT07525076
View directory record Official record
Conditions
HIV Infections, Syphilis Infection
Interventions
Chembio HIV/Syphilis rapid Point of Care (POC) test, Laboratory-based HIV and syphilis testing
Diagnostic Test
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
14 Years to 45 Years · Female only
Enrollment
1,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 2, 2026, 7:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Connecting Resources for Urban Sexual Health

NCT02183909
View directory record Official record
Conditions
HIV, Sexually Transmitted Infections
Interventions
Testing and linkage to care for Y/MSM, Engagement and retention for HIV-positive Y/MSM in care, Engagement and retention for HIV-negative Y/MSM in sexual health services, Stribild PEP Substudy
Other · Behavioral · Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 29 Years · Male only
Enrollment
378 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Dec 11, 2024 · Synced Sep 2, 2026, 7:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mobile-Based Application "MyChoices"

NCT03179319
View directory record Official record
Conditions
HIV, Sexually Transmitted Diseases, Pre-exposure Prophylaxis, Risk Reduction
Interventions
MyChoices
Behavioral
Lead sponsor
Fenway Community Health
Other
Eligibility
15 Years to 24 Years · Male only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
2
States / cities
Boston, Massachusetts • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Dec 15, 2020 · Synced Sep 2, 2026, 7:10 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Project AWARE: Using the Emergency Department (ED) to Prevent Sexually Transmitted Infections (STIs) in Youth

NCT01195220
View directory record Official record
Conditions
Chlamydia, Gonorrhea, HIV
Interventions
HIV testing, STI/HIV-T, STI/HIV-Plus
Behavioral
Lead sponsor
North Bronx Healthcare Network
Other
Eligibility
14 Years to 21 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 7, 2015 · Synced Sep 2, 2026, 7:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Home Self-Testing for HIV to Increase HIV Testing Frequency in Men Who Have Sex With Men (The iTest Study)

NCT01161446
View directory record Official record
Conditions
HIV
Interventions
Home HIV self-testing with OraQuick ADVANCE® Rapid HIV-1/2 Antibody Test, Home HIV self-testing with OraQuick ADVANCE® Rapid HIV-1/2 Antibody Test
Behavioral · Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Male only
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 6, 2017 · Synced Sep 2, 2026, 7:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acceptability, Feasibility and Preliminary Impact of OurPlan, an mHealth HIV Prevention Intervention for Male Couples

NCT04836091
View directory record Official record
Conditions
HIV/AIDS
Interventions
Waitlist, Intervention
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 15, 2021 · Synced Sep 2, 2026, 7:10 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Improving Prevention Systems to Reduce Disparities for High Priority Populations

NCT03778164
View directory record Official record
Conditions
HIV Infections
Interventions
Fast Track Partner Services-Sexual Health Intervention, Partner Services Standard of Care
Other
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
18 Years and older
Enrollment
1,150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 28, 2023 · Synced Sep 2, 2026, 7:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

mLab App Plus: A Randomized Controlled Trial of a Mobile Health (mHealth) Intervention

NCT06059443
View directory record Official record
Conditions
HIV Infections, Sexually Transmitted Diseases, Viral, Syphilis
Interventions
mLab App Plus
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 39 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
New York, New York • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced Sep 2, 2026, 7:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Mobile Intervention to Improve Uptake of PrEP for Southern Black MSM

NCT03308097
View directory record Official record
Conditions
Hiv
Interventions
PrEP Mobile Messaging Intervention, Enhanced Standard of Care
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Feb 20, 2021 · Synced Sep 2, 2026, 7:10 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effectiveness and Implementation of Text Messaging to Improve HIV Testing in Adolescents

NCT06096519
View directory record Official record
Conditions
HIV
Interventions
Information, motivation, behavioral skills treatment arm, Information only control arm
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
13 Years to 19 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 2, 2026, 7:10 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Eban II: Intervention for HIV Sero-Discordant Couples

NCT01829282
View directory record Official record
Conditions
Sexually Transmitted Diseases, Disease Transmission, Infectious, Safe Sex, HIV
Interventions
Risk Reduction
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 60 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
8
States / cities
Long Beach, California • Los Angeles, California • Oakland, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2016 · Synced Sep 2, 2026, 7:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CVCTPlus: A Couples-Based Approach to Linkage to Care and ARV Adherence

NCT01772992
View directory record Official record
Conditions
HIV
Interventions
CVCTPLUS
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Male only
Enrollment
586 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
4
States / cities
Atlanta, Georgia • Chicago, Illinois • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 27, 2020 · Synced Sep 2, 2026, 7:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Expanding PrEP By Embedding Unannounced SNAPS Navigators in High STI Testing Clinical Sites

NCT04207151
View directory record Official record
Conditions
Hiv, Sexually Transmitted Infection
Interventions
SNAPS intervention
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Sep 2, 2026, 7:10 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

A Comparative Effectiveness Demonstration Project for Linkage and Retention in PrEP Care for Men Who Have Sex With Men

NCT03442192
View directory record Official record
Conditions
Adherence, Patient
Interventions
PrEP Care Anywhere Services
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 99 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 8, 2022 · Synced Sep 2, 2026, 7:10 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Linking Youth to Pre-Exposure Prophylaxis (PrEP) Services

NCT07438041
View directory record Official record
Conditions
HIV, PrEP, PrEP Adherence
Interventions
LYPS, Enhanced Standard of Care
Other
Lead sponsor
Westat
Other
Eligibility
13 Years to 24 Years
Enrollment
272 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
4
States / cities
San Francisco, California • Atlanta, Georgia • Baltimore, Maryland + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 2, 2026, 7:10 AM EDT
Completed Not applicable Interventional

Development and Piloting of a Just-in-Time, Personalized HIV Prevention Intervention for Youth Experiencing Homelessness and Unstable Housing

NCT03911024
View directory record Official record
Conditions
Behavior, Risk
Interventions
HIV, General health
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 25 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 16, 2019 · Synced Sep 2, 2026, 7:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

HOME Study: a Combination Support Package to Increase Uptake of PrEP and HIV/STI Testing

NCT03138135
View directory record Official record
Conditions
HIV Prevention, Sexually Transmitted Diseases, Pre-Exposure Prophylaxis
Interventions
HOME Study intervention, Control
Behavioral
Lead sponsor
Public Health Foundation Enterprises, Inc.
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2021 · Synced Sep 2, 2026, 7:10 AM EDT