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Showing 1–24 of 267 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: HIV-ASSIST Clear all
Completed Not applicable Interventional Accepts healthy volunteers

The OPENS Trial: Offering Women PrEP (Aim 2)

NCT05619497
View directory record Official record
Conditions
Human Immunodeficiency Virus, Human Immunodeficiency Virus Transmission, Sexually Transmitted Diseases
Interventions
Clinic-wide Trainings, Clinic-wide Trainings and HIV Prevention Decision Support Tool (DST), Standard Care with the HIV Prevention Decision Support Tool (DST)
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 45 Years
Enrollment
141 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Sep 18, 2026, 4:45 AM EDT
Completed Not applicable Interventional Results available

Financial Incentives, Randomization With Stepped Treatment Trial

NCT03089320
View directory record Official record
Conditions
Unhealthy Alcohol Use
Interventions
Contingency Management Counseling, Addiction Physician Management, Motivational Enhancement Therapy
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
7
States / cities
Los Angeles, California • Washington D.C., District of Columbia • Atlanta, Georgia + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2024 · Synced Sep 18, 2026, 4:45 AM EDT
Completed Not applicable Interventional

Addressing Risk Through Community Treatment for Infectious Disease and Opioid Use Disorder Now (ACTION) Among Justice-involved Populations

NCT05286879
View directory record Official record
Conditions
Opioid Use Disorder, Infectious Disease, Risk Reduction Behavior, Substance Use, Substance Abuse, Stimulant Use Disorder
Interventions
Patient Navigator, Mobile Health Unit
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
601 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
3
States / cities
New Haven, Connecticut • Dallas, Texas • Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 18, 2026, 4:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Partner Services Pre-exposure Prophylaxis (PS-PrEP)

NCT02749955
View directory record Official record
Conditions
HIV Transmission, Transtheoretical Model of Change
Interventions
PS-PrEP Intervention Group, PrEPLine Control Group
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
164 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Sep 18, 2026, 4:45 AM EDT
Not yet recruiting Phase 3 Interventional Accepts healthy volunteers

Duo: A Phase IIIb Individual-Level Randomized Controlled Trial of an Integrated Strategy

NCT07658976
View directory record Official record
Conditions
HIV Infection, Sexually Transmitted Infection
Interventions
HIV PrEP - choice of F/TDF, F/TAF, or CAB-LA, STI PEP - Doxycycline as Doxy-PEP, 3P mHealth package, Handout about HIV PrEP options available at the site, Standard-of-care HIV PrEP counseling from qualified study staff
Drug · Behavioral
Lead sponsor
HIV Prevention Trials Network
Network
Eligibility
18 Years to 29 Years · Male only
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
2
States / cities
Los Angeles, California • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 18, 2026, 4:45 AM EDT
Completed Not applicable Interventional

Optimizing Kidney Transplant Informed Consent

NCT01859884
View directory record Official record
Conditions
End-stage Kidney Disease
Interventions
Inform Me: web-based education tool
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
21 Years and older
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Birmingham, Alabama • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 19, 2015 · Synced Sep 18, 2026, 4:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The OPENS Trial: Offering Women PrEP (Aim 1)

NCT04621760
View directory record Official record
Conditions
Human Immunodeficiency Virus Transmission, Sexually Transmitted Diseases
Interventions
HIV Prevention Decision Support Tool (DST), Standard Counseling
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 45 Years
Enrollment
189 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 18, 2026, 4:45 AM EDT
Completed Not applicable Interventional

Cooperative Re-Engagement Controlled Trial (CoRECT)

NCT02693145
View directory record Official record
Conditions
Human Immunodeficiency Virus
Interventions
Anti-Retroviral Treatment and Access to Services (ARTAS)
Other
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
18 Years and older
Enrollment
1,893 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
3
States / cities
Hartford, Connecticut • Boston, Massachusetts • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 20, 2021 · Synced Sep 18, 2026, 4:45 AM EDT
Completed Not applicable Interventional

Integrating ENGagement and Adherence Goals Upon Entry iENGAGE to Control HIV

NCT01900236
View directory record Official record
Conditions
HIV
Interventions
Based on behavioral motivational interviewing (MI) technique
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
371 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
4
States / cities
Birmingham, Alabama • Baltimore, Maryland • Chapel Hill, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2019 · Synced Sep 18, 2026, 4:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Culturally-Tailored HIV Risk Reduction for African-American MSM

NCT00691561
View directory record Official record
Conditions
HIV Infections
Interventions
Project ABLE
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older · Male only
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 10, 2010 · Synced Sep 18, 2026, 4:45 AM EDT
Not yet recruiting Not applicable Interventional

Project SPACE: Testing Daily Text Messages to Reduce Alcohol Use and HIV Risk Behavior

NCT07769580
View directory record Official record
Conditions
HIV, Risk Behavior, Alcohol Abuse
Interventions
CLT- Concrete text messages, CLT- Abstract text messages, Control messages, No messages, GamePlan Online Program
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 18, 2026, 4:45 AM EDT
Completed Not applicable Interventional

RETAIN: Retaining Opioid Users Entering Medication Assisted Treatment and Encouraging HCV/HIV Testing

NCT03411265
View directory record Official record
Conditions
Opioid-Related Disorders, Opioid-use Disorder, Drug Addiction, Substance Use Disorders
Interventions
self-administered, e-health application
Other
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 9, 2019 · Synced Sep 18, 2026, 4:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Program Refinements to Optimize Model Impact and Scalability Based on Evidence

NCT03628287
View directory record Official record
Conditions
Hiv
Interventions
Revised Care Coordination Program, Original Care Coordination Program
Other
Lead sponsor
City University of New York, School of Public Health
Other
Eligibility
18 Years and older
Enrollment
960 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
17
States / cities
Brooklyn, New York • Elmhurst, New York • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Sep 18, 2026, 4:45 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Multidisciplinary Low-Barrier and Mobile HIV Care to Improve Retention and Viral Suppression: Stakeholder-Engaged Design and Evaluation

NCT05887557
View directory record Official record
Conditions
HIV
Interventions
Active Referral, Drop-In Multidisciplinary HIV Care, Mobile HIV Care, Staged Care, Identify and prepare champions at referral sites, Audit and feedback at referral sites, Build a coalition among referral and clinical sites, Assess for readiness and identify barriers, Promote adaptability, Develop a formal implementation blueprint, Develop educational materials; conduct ongoing training, Create a learning collaborative
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
15 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
5
States / cities
Oakland, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Sep 18, 2026, 4:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mobile-health (mHealth) Intervention to Support HIV Self-testing and PrEP Uptake Among Young Men Who Have Sex With Men

NCT04865341
View directory record Official record
Conditions
Human Immunodeficiency Virus
Interventions
IMB, Information-Only Control
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
17 Years to 24 Years · Male only
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 18, 2026, 4:45 AM EDT
Completed No phase listed Observational

Engaging Care for HIV-infected Adolescent Females.

NCT00489034
View directory record Official record
Conditions
HIV Infection
Interventions
Quantitative Interview, Ethnographic Interview, Gender Interview
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
13 Years to 23 Years · Female only
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
5
States / cities
Los Angeles, California • Miami, Florida • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 5, 2017 · Synced Sep 18, 2026, 4:45 AM EDT
Terminated Not applicable Interventional

Computer-Assisted Adherence Program for Patients Taking Anti-HIV Drugs

NCT00051766
View directory record Official record
Conditions
Acquired Immunodeficiency Syndrome, HIV Infections
Interventions
Computer-based Intervention
Behavioral
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
16 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Sep 18, 2026, 4:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Y2Prevent: Preventing Drug Use and HIV Through Empowerment, Social Support and Mentorship (Y2P)

NCT04504981
View directory record Official record
Conditions
HIV, Drug Use
Interventions
Y2Prevent
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
18 Years to 24 Years · Male only
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 17, 2023 · Synced Sep 18, 2026, 4:45 AM EDT
Completed Not applicable Interventional

Testing an Online Intervention to Improve Parents' Communication With Gay and Bisexual Sons About Sex and HIV

NCT04018573
View directory record Official record
Conditions
HIV Infections
Interventions
PATHS Sexual Communication Toolkit, Parent Support Film
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 4, 2023 · Synced Sep 18, 2026, 4:45 AM EDT
Completed Not applicable Interventional Results available

Brief Acceptance-Based Retention Intervention for Newly Diagnosed HIV Patients

NCT04201288
View directory record Official record
Conditions
HIV/AIDS
Interventions
Acceptance-Based Behavior Therapy (ABBT), Enhanced-Treatment-as-Usual (ETAU)
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Sep 18, 2026, 4:45 AM EDT
Completed Phase 4 Interventional Results available

Smartphone Intervention for Smoking Cessation and Improving Adherence to Treatment Among HIV Patients

NCT03999411
View directory record Official record
Conditions
Smoking, Smoking Cessation, HIV
Interventions
Nicoderm C-Q Transdermal Product, Adherence to Antiretroviral Therapy Counseling, Behavioral Smoking Cessation Counseling, "Crave-to-Quit" app, vDOT "emocha" app
Drug · Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 27, 2024 · Synced Sep 18, 2026, 4:45 AM EDT
Completed Not applicable Interventional

Evaluation of the Texas Wellness Incentives and Navigation (WIN) Project

NCT02440906
View directory record Official record
Conditions
Chronic Mental Illness, Chronic Physical Illness
Interventions
Patient-Directed Wellness Account, Health Navigator
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 55 Years
Enrollment
1,663 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 2, 2017 · Synced Sep 18, 2026, 4:45 AM EDT
Enrolling by invitation Not applicable Interventional

Promoting Aging and Thriving With HIV

NCT07192419
View directory record Official record
Conditions
HIV (Human Immunodeficiency Virus), Geriatric, Geriatric Assessment, HIV, HIV - Human Immunodeficiency Virus
Interventions
Promoting Aging and Thriving with HIV (PATH)-Implementation of a Tailored Geriatric Assessment and Management Strategy for HIV Care Settings
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
50 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Sep 18, 2026, 4:45 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Collaborative Care PrTNER Study

NCT06585631
View directory record Official record
Conditions
HIV, Substance Use Disorders, Substance Use, AIDS
Interventions
CC PrTNER
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
15 Years to 29 Years · Male only
Enrollment
275 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
2
States / cities
Baltimore, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 18, 2026, 4:45 AM EDT