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ClinicalTrials.gov public records Last synced Oct 21, 2026, 4:28 AM EDT

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Showing 1–24 of 330 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: HOPE Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Preventing Suicide in African American Adolescents

NCT04253002
View directory record Official record
Conditions
Suicide
Interventions
Robinson's Culturally Adapted Coping with Stress Course (A-CWS), Standard Care Control Condition
Behavioral
Lead sponsor
DePaul University
Other
Eligibility
12 Years and older
Enrollment
512 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
6
States / cities
Chicago, Illinois • Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 5, 2024 · Synced Oct 21, 2026, 4:28 AM EDT
Completed Phase 1 Interventional

Omega-3 and Therapy Study for Childhood Bipolar Disorder- Not Otherwise Specified

NCT01507753
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Omega-3 Supplementation, Psychoeducational Psychotherapy (PEP), Placebo
Drug · Behavioral · Other
Lead sponsor
L. Eugene Arnold
Other
Eligibility
7 Years to 14 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 8, 2016 · Synced Oct 21, 2026, 4:28 AM EDT
Completed Not applicable Interventional Results available

Piloting Pathways With Lung Cancer Patients

NCT04161157
View directory record Official record
Conditions
Metastatic Lung Cancer
Interventions
Pathways
Behavioral
Lead sponsor
Laurie McLouth
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 5, 2023 · Synced Oct 21, 2026, 4:28 AM EDT
Withdrawn Phase 1Phase 2 Interventional

A Clinical Trial to Determine the Safety and Efficacy of Hope Biosciences Autologous Mesenchymal Stem Cell Therapy (HB-adMSCs) for the Treatment of Alzheimer's Disease

NCT04228666
View directory record Official record
Conditions
Alzheimer Disease
Interventions
HB-adMSCs
Biological
Lead sponsor
Hope Biosciences LLC
Industry
Eligibility
50 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Oct 21, 2026, 4:28 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Journey of Hope in Appalachia: Supporting Resilience in the Region's Youth

NCT04096937
View directory record Official record
Conditions
Adverse Childhood Experiences
Interventions
Focus groups
Other
Lead sponsor
Gia Mudd
Other
Eligibility
10 Years to 99 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
2
States / cities
Hazard, Kentucky • Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Nov 25, 2022 · Synced Oct 21, 2026, 4:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Postoperative Pain and Healing in Teeth Treated With GentleWave or EndoActivator

NCT04552132
View directory record Official record
Conditions
Symptomatic Irreversible Pulpitis, Apical Periodontitis
Interventions
Multisonic vs Sonic activation of irrigants
Device
Lead sponsor
St. Louis University
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 15, 2023 · Synced Oct 21, 2026, 4:28 AM EDT
Recruiting Not applicable Interventional

Hybrid Type 1 Randomized Pilot Trial of a Peer-led Family and Social Strengthening Group Intervention for Refugee Families

NCT06261463
View directory record Official record
Conditions
Depression, Anxiety, PTSD, Family Dynamics, Social Functioning, Family Support, Family Relations
Interventions
CAFES2
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
12 Years to 55 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Oct 21, 2026, 4:28 AM EDT
Completed Not applicable Interventional Results available

Peer Mentorship to Reduce Suicide Attempts Among High-Risk Adults

NCT03373916
View directory record Official record
Conditions
Suicidal Ideation
Interventions
Peer mentorship, Enhanced Usual Care
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
455 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
3
States / cities
Ann Arbor, Michigan • Ferndale, Michigan • Mount Clemens, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced Oct 21, 2026, 4:28 AM EDT
Not yet recruiting Not applicable Interventional

THRIVE: A Recovery-Focused Suicide Prevention Intervention in Crisis Stabilization Centers

NCT07784634
View directory record Official record
Conditions
Suicide
Interventions
Toward Hope, Recovery, Interpersonal Growth, Values, and Engagement (THRIVE), Center Care as Usual
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
552 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
3
States / cities
Huntsville, Alabama • Phoenix, Arizona • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 21, 2026, 4:28 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

The Hurria Older PatiEnts (HOPE) With Breast Cancer Study

NCT01472094
View directory record Official record
Conditions
Breast Cancer
Interventions
Not listed
Lead sponsor
City of Hope Medical Center
Other
Eligibility
65 Years and older
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2027
U.S. locations
17
States / cities
Duarte, California • New Haven, Connecticut • Chicago, Illinois + 12 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 21, 2026, 4:28 AM EDT
Completed Not applicable Interventional Results available

Multi-Component Intervention to Improve Health Outcomes and Quality of Life Among Rural Older Adults Living With HIV

NCT04549259
View directory record Official record
Conditions
HIV
Interventions
Group-Based Social Support, HIV Stigma Reduction, Strengths-Based Case Management (SBCM), Personalized Technology Detailing
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
50 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 12, 2023 · Synced Oct 21, 2026, 4:28 AM EDT
Completed Not applicable Interventional

Harnessing Online Peer Education Opioid Study

NCT05814315
View directory record Official record
Conditions
Medication Compliance, Pain
Interventions
HOPE Intervention
Behavioral
Lead sponsor
ElevateU
Industry
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Corona del Mar, California
Source: ClinicalTrials.gov public record
Updated Apr 14, 2023 · Synced Oct 21, 2026, 4:28 AM EDT
Recruiting Not applicable Interventional

Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)

NCT06263426
View directory record Official record
Conditions
Hiv
Interventions
HIV D-/R+
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
18
States / cities
Birmingham, Alabama • Sacramento, California • San Diego, California + 11 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 21, 2026, 4:28 AM EDT
Completed Not applicable Interventional

Single Session Intervention to Promote Hope

NCT06375876
View directory record Official record
Conditions
Domestic Violence
Interventions
Single-session intervention (SSI)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 21, 2026, 4:28 AM EDT
Recruiting Not applicable Interventional

Reducing the Duration of Untreated Psychosis in the United States: The Impact of Screening and Systematic Communication

NCT05509998
View directory record Official record
Conditions
First Episode Psychosis (FEP), Clinical High Risk for Psychosis (CHR)
Interventions
Screening Method (SM), Screening and Communication Method (SCM)
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
12 Years to 30 Years
Enrollment
912 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 21, 2026, 4:28 AM EDT
Completed No phase listed Observational Results available

Impact of a Financial Success Education Program in Women and Children

NCT01409291
View directory record Official record
Conditions
Stress
Interventions
Not listed
Lead sponsor
Creighton University
Other
Eligibility
3 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 26, 2014 · Synced Oct 21, 2026, 4:28 AM EDT
Terminated Not applicable Interventional

Reducing Readmissions in High-Risk Ostomates

NCT02658123
View directory record Official record
Conditions
Ileostomy
Interventions
Pre-operative education (standard of care), Home health care visits (standard of care), Follow-up post-operative visits, Patient Data Collection Form, Healthcare Utilization Form, The City of Hope QOL Survey for Ostomy Patients, Phone call with CWOCN or PA
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 1, 2018 · Synced Oct 21, 2026, 4:28 AM EDT
Completed Not applicable Interventional

Peer Mentorship to Reduce Suicide Risk Following Psychiatric Hospitalization

NCT02365116
View directory record Official record
Conditions
Suicidal Ideation
Interventions
Peer mentorship, Enhanced Usual Care
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
2
States / cities
Ann Arbor, Michigan • Ferndale, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 15, 2017 · Synced Oct 21, 2026, 4:28 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

BREATHE Free Curriculum

NCT06862050
View directory record Official record
Conditions
Smoking Cessation; Tobacco Dependence, E-Cig Use, Nicotine Dependence, Other Tobacco Product
Interventions
BREATHE Free Curriculum
Behavioral
Lead sponsor
Augusta University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 21, 2026, 4:28 AM EDT
Completed Phase 4 Interventional Results available

Remission Through Early Monitored Insulin Therapy - Duration Month

NCT03670641
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Glargine, Lispro, Dexcom G6
Drug · Device
Lead sponsor
Sandra Sobel
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 12, 2021 · Synced Oct 21, 2026, 4:28 AM EDT
Completed Not applicable Interventional Results available

Adaptability and Resilience in Aging Adults-2

NCT04068922
View directory record Official record
Conditions
Aging, Chronic Low-back Pain
Interventions
Resilience Intervention
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
60 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 31, 2024 · Synced Oct 21, 2026, 4:28 AM EDT
Completed Not applicable Interventional Results available

Peer Based Suicide Prevention

NCT04222673
View directory record Official record
Conditions
Suicide
Interventions
Peer Specialist Suicide Prevention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
3
States / cities
West Haven, Connecticut • Ann Arbor, Michigan • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Oct 21, 2026, 4:28 AM EDT
No Longer Available No phase listed Expanded access

"Individual Patient Expanded Access IND to Treat Primary Lateral Sclerosis"

NCT04825613
View directory record Official record
Conditions
Primary Lateral Sclerosis, Adult, 1
Interventions
HB-adMSCs
Biological
Lead sponsor
Hope Biosciences Research Foundation
Industry
Eligibility
18 Years and older · Male only
U.S. locations
1
States / cities
Sugar Land, Texas
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Oct 21, 2026, 4:28 AM EDT
Withdrawn Phase 2 Interventional

Treatment of Lung Injury From COVID-19 Infection With Intravenous Sodium Nitrite

NCT04401527
View directory record Official record
Conditions
COVID-19, Acute Respiratory Distress Syndrome, Acute Respiratory Failure
Interventions
Sodium Nitrite, Normal Saline
Drug
Lead sponsor
Hope Pharmaceuticals
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
2
States / cities
Tampa, Florida • Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Sep 16, 2020 · Synced Oct 21, 2026, 4:28 AM EDT