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Showing 1–24 of 327 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: HOPE Clear all
Not listed Phase 2 Interventional

Healthy Outcomes of Pregnancy Education

NCT00381823
View directory record Official record
Conditions
Environmental Tobacco Smoke Exposure, Depression, Partner Abuse, Tobacco Smoking
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years and older · Female only
Enrollment
1,750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 28, 2006 · Synced Sep 5, 2026, 10:09 AM EDT
Completed No phase listed Observational

Overcontrol and Suicide in PTSD

NCT06355284
View directory record Official record
Conditions
Compulsive Personality Disorder, Stress Disorders, Post-Traumatic
Interventions
Functional MRI
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 5, 2026, 10:09 AM EDT
Completed Not applicable Interventional Results available

HEARTPrep: A Virtually-delivered Psychosocial Intervention for Mothers Expecting a Baby With Congenital Heart Disease

NCT05129631
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
HEARTPrep
Behavioral
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 5, 2026, 10:09 AM EDT
Terminated No phase listed Observational

Pennsylvania Consortium: Clinical Database

NCT00718445
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis, Neurodegenerative Disease, Motor Neuron Disease
Interventions
Not listed
Lead sponsor
Drexel University College of Medicine
Other
Eligibility
18 Years to 89 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 26, 2016 · Synced Sep 5, 2026, 10:09 AM EDT
No Longer Available No phase listed Expanded access

HBCMD01- Expanded Access for the Treatment of Congenital Muscular Dystrophy.

NCT05154851
View directory record Official record
Conditions
Congenital Muscular Dystrophy Due to Lamin A/C Mutation
Interventions
HB-adMSCs
Biological
Lead sponsor
Hope Biosciences Research Foundation
Industry
Eligibility
Not listed
U.S. locations
1
States / cities
Sugar Land, Texas
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Sep 5, 2026, 10:09 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Long-term Neurocognitive Sequelae of Subclinical Microembolization During Carotid Interventions

NCT01718600
View directory record Official record
Conditions
Carotid Artery Stenosis
Interventions
Neuropsychological testing
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
40 Years and older
Enrollment
207 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2018
U.S. locations
3
States / cities
Palo Alto, California • St Louis, Missouri • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 28, 2022 · Synced Sep 5, 2026, 10:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Southwest Hub for American Indian Youth Suicide Prevention Research

NCT03543865
View directory record Official record
Conditions
Suicide, Surveillance, Mental Health, Substance Use, Depressive Symptoms
Interventions
New Hope (NH), Elders Resilience (ER), Case Management (CM)
Behavioral · Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
16 Years to 29 Years
Enrollment
304 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Whiteriver, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Sep 5, 2026, 10:09 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Project HOPEFUL: A PN-RCT With Implementation Science

NCT07475039
View directory record Official record
Conditions
Older Adults (50-90 Years), Mental Health, Depression and Suicide Ideation, Social Functioning, Quality of Life, Thwarted Belongingness, Perceived Burdensomeness
Interventions
Standardized and manualized warm calls from providers trained in the BE training, Standardized and manualized warm calls from providers trained in the BE training + ASIST training
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
55 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Sep 5, 2026, 10:09 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Oocyte Cryopreservation Registry (HOPE Registry)

NCT00699400
View directory record Official record
Conditions
Oocyte Cryopreservation
Interventions
Not listed
Lead sponsor
EMD Serono
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
204 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
15
States / cities
Fountain Valley, California • Laguna Hills, California • Newport Beach, California + 11 more
Source: ClinicalTrials.gov public record
Updated Jan 23, 2014 · Synced Sep 5, 2026, 10:09 AM EDT
Recruiting Not applicable Interventional

Preliminary Trial of an Avatar Guided Digital Intervention for Emerging Adults

NCT07418047
View directory record Official record
Conditions
Binge Alcohol Consumption, Suicidal Ideation
Interventions
EA-Avatar, Suicide safety planning app
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years to 29 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Marlborough, Massachusetts • Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 5, 2026, 10:09 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Randomized, Double-Blind, Single Center, Efficacy and Safety Study of Allogeneic HB-adMSCs Against COVID-19.

NCT04348435
View directory record Official record
Conditions
COVID-19
Interventions
HB-adMSCs, Placebos
Biological · Other
Lead sponsor
Hope Biosciences Research Foundation
Industry
Eligibility
Not listed
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Sugar Land, Texas
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Sep 5, 2026, 10:09 AM EDT
Not yet recruiting Not applicable Interventional

Recovery-oriented Group Therapy for Veteran Men With Military Sexual Trauma

NCT06741202
View directory record Official record
Conditions
Sexual Trauma
Interventions
Men's MST Group, Present-Centered Group Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Male only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 5, 2026, 10:09 AM EDT
Active, not recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women

NCT05552053
View directory record Official record
Conditions
Pregnancy Related, Pregnancy Complications, Pregnancy, High Risk, Depression, Depression, Postpartum, Perinatal Depression, Anxiety, Anxiety in Pregnancy, Stress, Psychological, Racism, Discrimination, Racial, Inflammation
Interventions
MWSH plus Candlelit Care, MWSH
Device
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 5, 2026, 10:09 AM EDT
Completed Not applicable Interventional Results available

Piloting Pathways With Lung Cancer Patients

NCT04161157
View directory record Official record
Conditions
Metastatic Lung Cancer
Interventions
Pathways
Behavioral
Lead sponsor
Laurie McLouth
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 4, 2023 · Synced Sep 5, 2026, 10:09 AM EDT
Enrolling by invitation Not applicable Interventional

Positive Assurance and mTBI

NCT04982731
View directory record Official record
Conditions
MTBI - Mild Traumatic Brain Injury, Concussion, Mild Traumatic Brain Injury
Interventions
Positive Assurance
Other
Lead sponsor
Inova Health Care Services
Other
Eligibility
13 Years to 21 Years
Enrollment
229 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Sep 5, 2026, 10:09 AM EDT
Active, not recruiting Phase 2 Interventional Results available

Clofarabine and Melphalan Before Donor Stem Cell Transplant in Treating Patients With Myelodysplasia, Acute Leukemia in Remission, or Chronic Myelomonocytic Leukemia

NCT01885689
View directory record Official record
Conditions
Adult Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Adult Acute Myeloid Leukemia in Remission, Myelodysplastic Syndrome, Secondary Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia, Therapy-Related Myelodysplastic Syndrome
Interventions
clofarabine, melphalan, allogeneic hematopoietic stem cell transplantation, tacrolimus, sirolimus, Pharmacological Study
Drug · Procedure · Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2026
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 5, 2026, 10:09 AM EDT
Suspended Phase 1 Interventional

Total Marrow and Lymphoid Irradiation Before Donor Transplant and Cyclophosphamide in Treating Patients With Acute Myeloid Leukemia

NCT03467386
View directory record Official record
Conditions
Acute Myeloid Leukemia
Interventions
Allogeneic Hematopoietic Stem Cell Transplantation, Cyclophosphamide, Filgrastim, Laboratory Biomarker Analysis, Quality-of-Life Assessment, Questionnaire Administration, Tacrolimus, Total Marrow Irradiation
Procedure · Drug · Biological + 2 more
Lead sponsor
City of Hope Medical Center
Other
Eligibility
16 Years to 60 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 5, 2026, 10:09 AM EDT
Recruiting Not applicable Interventional

Enhancing the Effectiveness of Prolonged Exposure Among Suicidal Individuals With PTSD

NCT06285708
View directory record Official record
Conditions
PTSD, Suicidal Ideation, Suicide, Attempted, Trauma, Psychological
Interventions
Prolonged exposure
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 5, 2026, 10:09 AM EDT
No Longer Available No phase listed Expanded access

An Expanded Access IND for the Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

NCT04825626
View directory record Official record
Conditions
Chronic Inflammatory Demyelinating Polyneuropathy
Interventions
HB-adMSCs
Biological
Lead sponsor
Hope Biosciences Research Foundation
Industry
Eligibility
Not listed
U.S. locations
1
States / cities
Sugar Land, Texas
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Sep 5, 2026, 10:09 AM EDT
Completed Not applicable Interventional Results available

High-Intensity Exercise to Attenuate Limitations and Train Habits in Older Adults With HIV

NCT04550676
View directory record Official record
Conditions
Hiv, Fatigue, Mobility Limitation
Interventions
HIIT (intervention), CME (active control), Coaching, Control text message
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years and older
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Aurora, Colorado • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 5, 2026, 10:09 AM EDT
Completed Not applicable Interventional Results available

Treatment of PTSD in Residents of Battered Women's Shelters

NCT02398227
View directory record Official record
Conditions
PTSD
Interventions
HOPE, PCT
Behavioral
Lead sponsor
The University of Akron
Other
Eligibility
Female only
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 9, 2018 · Synced Sep 5, 2026, 10:09 AM EDT
Completed Not applicable Interventional

Pretransplant Evaluation by Supportive Care Team for Patients Undergoing HCT for Hematological Malignancies

NCT02321345
View directory record Official record
Conditions
Malignancies, Hematologic
Interventions
Palliative Care Support
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 22, 2018 · Synced Sep 5, 2026, 10:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Forging Hopeful Futures to Reduce Youth Violence

NCT05743478
View directory record Official record
Conditions
Violence in Adolescence, Racism, Adolescent Behavior, Coping Skills, Communication, Social, Communication, Personal, Violence, Sexual, Violence, Non-accidental, Violence, Physical, Violence, Gender-Based
Interventions
Forging Hopeful Futures, Wellness Check-ins
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
13 Years to 19 Years
Enrollment
542 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 5, 2026, 10:09 AM EDT