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Conditions: Recurrent Ovarian Carcinoma
Interventions: Behavioral Intervention, Electronic Health Record Review, Interview, Survey Administration; Behavioral · Other
Lead sponsor: Fred Hutchinson Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: COVID-19, Acute Respiratory Distress Syndrome, Acute Respiratory Failure
Interventions: Sodium Nitrite, Normal Saline; Drug
Lead sponsor: Hope Pharmaceuticals; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 2
States / cities: Tampa, Florida • Fort Worth, Texas

Conditions: Congenital Muscular Dystrophy Due to Lamin A/C Mutation
Interventions: HB-adMSCs; Biological
Lead sponsor: Hope Biosciences Research Foundation; Industry
Eligibility: Not listed
U.S. locations: 1
States / cities: Sugar Land, Texas

Conditions: Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Endometrial Carcinoma, Endometrial Endometrioid Adenocarcinoma, Female Reproductive System Neoplasm, Stage II Ovarian Cancer AJCC v8, Stage III Ovarian Cancer AJCC v8, Stage III Vaginal Cancer AJCC v8, Stage III Vulvar Cancer AJCC v8, Stage IV Ovarian Cancer AJCC v8, Stage IV Vaginal Cancer AJCC v8, Stage IV Vulvar Cancer AJCC v8, Triple-Negative Breast Carcinoma
Interventions: Behavioral Intervention, Educational Intervention, Internet-Based Intervention, Interview, Survey Administration, Virtual Technology Intervention; Behavioral · Other
Lead sponsor: City of Hope Medical Center; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 12
States / cities: Arcadia, California • Duarte, California • Irvine, California + 8 more

Conditions: Suicidal Ideation, Suicide, Attempted, Ptsd
Interventions: Cognitive Processing Therapy (CPT), Crisis Response Plan (CRP), Safety Planning Intervention (SPI), Narrative Assessment; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 157 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Heart Defects, Congenital, Hypoplastic Left Heart Syndrome, Single Ventricle Defect, Stress, Psychological
Interventions: Early palliative care team consultation; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older · Female only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Opioid Use Disorder, Intimate Partner Violence (IPV), Post Traumatic Stress Disorder PTSD
Interventions: PCT+2HOPE; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 532 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 3
States / cities: Bridgeport, Connecticut • Enfield, Connecticut • West Haven, Connecticut

Conditions: Post-Traumatic Stress Disorder, Battered Women
Interventions: Helping to Overcome PTSD through Empowerment (HOPE), Treatment as usual; Behavioral
Lead sponsor: The University of Akron; Other
Eligibility: 18 Years and older · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Akron, Ohio

Conditions: Suicide Prevention, Suicide Attempt, Suicide Ideation
Interventions: Virtual Hope Box Enhanced Facilitation, Enhanced Usual Care; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 928 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Parkinson Disease
Interventions: HB-adMSCs, Placebo; Biological · Other
Lead sponsor: Hope Biosciences Research Foundation; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Sugar Land, Texas

Conditions: Post Traumatic Stress Disorder
Interventions: Narrative Exposure Therapy; Behavioral
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Suicide, Suicide Ideation, Suicidal Behavior, Hope, Financial Stress
Interventions: From Hardship to Hope: A Peer-led intervention to reduce financial hardship and suicide risk, Enhanced Treatment as Usual (eTAU); Behavioral · Other
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 64 Years
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Neonatal Abstinence Syndrome
Interventions: Structured psychosocial intervention; Behavioral
Lead sponsor: Dr. Henry Akinbi; Other
Eligibility: Female only
Enrollment: 113 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Suicide
Interventions: Continuous Identity Cognitive Therapy (CI-CT), General Health Education; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Advanced Cancer
Interventions: Masterful supportive care, Attention control supportive care; Other
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Acute Kidney Injury
Interventions: Allogeneic HB-adMSCs, Normal Saline; Drug
Lead sponsor: Hope Biosciences LLC; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 3
States / cities: Birmingham, Alabama • San Francisco, California • Houston, Texas

Conditions: Chronic Pain
Interventions: PsychoEducation, Self-Hypnosis Training, Mindfulness Meditation; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 343 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 5
States / cities: Seattle, Washington • Tacoma, Washington

Conditions: Giant Axonal Neuropathy (GAN)
Interventions: scAAV9/JeT-GAN; Genetic
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 10 Years to 25 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2032
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Depression, Anxiety, Adolescent Behavior, Suicidal Ideation
Interventions: IPR + GMI; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 10 Years to 18 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Kittanning, Pennsylvania

Conditions: Schizophrenia
Interventions: Cognitive Enhancement Therapy, Social Skills Training; Behavioral
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Crohn Disease (CD)
Interventions: HB-adMSCs - Hope Biosciences Adipose Derived Mesenchymal Stem Cells, 0.9% sodium chloride; Drug
Lead sponsor: Hope Biosciences Research Foundation; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Sugar Land, Texas

Conditions: Suicidal Ideation, Suicide Attempt
Interventions: CAMS Single Session Consultation, Driver Focused Skills Training, Caregiver Skills Training, Lethal Means Safety; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 13 Years to 21 Years
Enrollment: 184 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Brain Injury
Interventions: HB- adMSCs (Hope Biosciences adipose derived mesenchymal stem cells); Biological
Lead sponsor: Hope Biosciences Research Foundation; Industry
Eligibility: 14 Years to 78 Years
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Aplastic Anemias, Hemoglobinopathies, Bone Marrow Failure
Interventions: Not listed
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: Not listed
Enrollment: 375 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2031
U.S. locations: 14
States / cities: Duarte, California • Gainesville, Florida • Atlanta, Georgia + 10 more

Search by objective public record fields.

Helping Ovarian Cancer Patients Cope With Their Illness (HOPE)

Treatment of Lung Injury From COVID-19 Infection With Intravenous Sodium Nitrite

HBCMD01- Expanded Access for the Treatment of Congenital Muscular Dystrophy.

Virtual Mental Health Intervention to Address Fear of Progression for Women With High Risk or Stage III-IV Gynecologic or Breast Cancer

Improving Treatment Outcomes for Suicidal Veterans With PTSD

Impact of Early Intervention on Maternal Stress in Mothers of Fetuses Diagnosed With Single Ventricle Physiology

Project STRONGER: Stepped Care for Opioid Use Disorder Treatment Engagement and Recovery

Cognitive Behavioral Therapy for Treating Recently Abused Women With Post-Traumatic Stress Disorder

Smartphone App Enhanced Facilitation Among Veterans in a Mental Health Inpatient Setting (Project HOPE)

Randomized, Double-Blind Clinical Trial for Parkinson's Disease (Early and Moderate)

Feasibility Trial of Narrative Exposure Therapy (NET) for Posttraumatic Stress Disorder (PTSD) During Pregnancy

From Hardship to Hope: A Peer-led Intervention to Reduce Financial Hardship and Suicide Risk

Utility of Psychosocial Intervention in Improving Outcome for Methadone-exposed Infants and Their Mothers

Development of a Recovery Oriented Treatment for Post-Acute Suicidal Episode (PASE) Veterans

Meaning-Centered Intervention for Muslim Patients Who Are Being Treated for Advanced Cancer

Allogeneic HB-adMSCs vs Placebo for the Treatment of Acute Kidney Injury

Chronic Pain Skills Study

Intraneural Administration of scAAV9/JeT-GAN Into the Vagus Nerve for Patients With Giant Axonal Neuropathy (GAN)

Bridging the Gap to Improve Mental Health Treatment Utilization

What the Nose Knows: Hedonic Capacity, Psychosocial Interventions and Outcomes in Schizophrenia

HB-adMSCs for the Treatment of Crohn's Disease

Swift Outpatient Alternatives for Rapid Stabilization

Intermediate Size Patient Population Expanded Access Protocol to Evaluate HB-adMSCs for the Treatment of Patients With Traumatic or Nontraumatic Brain Injury

The HOPE Biobank Resource (BMT CTN 2402 HOPE)