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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: HOPE intervention Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Project HOPEFUL: A PN-RCT With Implementation Science

NCT07475039
View directory record Official record
Conditions
Older Adults (50-90 Years), Mental Health, Depression and Suicide Ideation, Social Functioning, Quality of Life, Thwarted Belongingness, Perceived Burdensomeness
Interventions
Standardized and manualized warm calls from providers trained in the BE training, Standardized and manualized warm calls from providers trained in the BE training + ASIST training
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
55 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Sep 17, 2026, 6:42 PM EDT
Active, not recruiting Not applicable Interventional

Meaning-Centered Intervention for Muslim Patients Who Are Being Treated for Advanced Cancer

NCT04435444
View directory record Official record
Conditions
Advanced Cancer
Interventions
Masterful supportive care, Attention control supportive care
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 17, 2026, 6:42 PM EDT
Not yet recruiting Not applicable Interventional

HOPE Intervention for Fitness

NCT07114822
View directory record Official record
Conditions
Diabetes Mellitus Type 2
Interventions
Harnessing Online Peer Education
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 17, 2026, 6:42 PM EDT
Completed Phase 4 Interventional

Interpersonal Therapy for Depression in Breast Cancer

NCT01191580
View directory record Official record
Conditions
Major Depression
Interventions
Interpersonal Psychotherapy, Problem-Solving Therapy, Brief Supportive Psychotherapy
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 90 Years
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 17, 2017 · Synced Sep 17, 2026, 6:42 PM EDT
Recruiting Not applicable Interventional

HOPE-BP 2.0: Evaluating the Optimal Duration of Postpartum Remote Blood Pressure Monitoring

NCT07204756
View directory record Official record
Conditions
Postpartum, Hypertension, Hypertensive Disorder of Pregnancy
Interventions
2-Week Home Monitoring, 6-Week Home Monitoring
Diagnostic Test
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older · Female only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 17, 2026, 6:42 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Randomized, Double-Blind, Single Center, Efficacy and Safety Study of Allogeneic HB-adMSCs Against COVID-19.

NCT04348435
View directory record Official record
Conditions
COVID-19
Interventions
HB-adMSCs, Placebos
Biological · Other
Lead sponsor
Hope Biosciences Research Foundation
Industry
Eligibility
Not listed
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Sugar Land, Texas
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Sep 17, 2026, 6:42 PM EDT
Completed Not applicable Interventional

Stress Reduction in Improving Quality of Life in Patients With Recurrent Gynecologic or Breast Cancer

NCT01764789
View directory record Official record
Conditions
Anxiety Disorder, Depression, Fatigue, Leydig Cell Tumor, Ovarian Sarcoma, Ovarian Stromal Cancer, Pain, Peritoneal Carcinomatosis, Pseudomyxoma Peritonei, Recurrent Breast Cancer, Recurrent Cervical Cancer, Recurrent Endometrial Carcinoma, Recurrent Fallopian Tube Cancer, Recurrent Gestational Trophoblastic Tumor, Recurrent Ovarian Epithelial Cancer, Recurrent Ovarian Germ Cell Tumor, Recurrent Primary Peritoneal Cavity Cancer, Recurrent Uterine Sarcoma, Recurrent Vaginal Cancer, Recurrent Vulvar Cancer
Interventions
questionnaire administration, quality-of-life assessment, psychosocial assessment and care, behavioral intervention, cognitive intervention, educational intervention
Other · Procedure · Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
21 Years to 85 Years · Female only
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 8, 2015 · Synced Sep 17, 2026, 6:42 PM EDT
Recruiting Not applicable Interventional

Swift Outpatient Alternatives for Rapid Stabilization

NCT05996172
View directory record Official record
Conditions
Suicidal Ideation, Suicide Attempt
Interventions
CAMS Single Session Consultation, Driver Focused Skills Training, Caregiver Skills Training, Lethal Means Safety
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
13 Years to 21 Years
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Sep 17, 2026, 6:42 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Restoring Empowerment and Choosing Hope (REACH)

NCT05299138
View directory record Official record
Conditions
Intervention, Wait List Control
Interventions
Marriage and Relationship Enhancement Skills (MRES) Intervention
Behavioral
Lead sponsor
Jewish Family & Children's Service of the Suncoast, Inc.
Other
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Sarasota, Florida
Source: ClinicalTrials.gov public record
Updated Feb 26, 2025 · Synced Sep 17, 2026, 6:42 PM EDT
Completed Not applicable Interventional

Improving Psychosocial Quality of Life in Women With Advanced Breast Cancer

NCT01811264
View directory record Official record
Conditions
Breast Cancer
Interventions
Patient-Participation Aid
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
21 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
2
States / cities
Tampa, Florida • Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Jul 13, 2017 · Synced Sep 17, 2026, 6:42 PM EDT
Active, not recruiting Not applicable Interventional

Home Rehabilitation Improves Cardiac Effort in Pulmonary Arterial Hypertension

NCT06477640
View directory record Official record
Conditions
Pulmonary Arterial Hypertension PAH
Interventions
Exercise, Standard of Care
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Sep 17, 2026, 6:42 PM EDT
Completed Not applicable Interventional Results available

Peer Mentorship to Reduce Suicide Attempts Among High-Risk Adults

NCT03373916
View directory record Official record
Conditions
Suicidal Ideation
Interventions
Peer mentorship, Enhanced Usual Care
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
455 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
3
States / cities
Ann Arbor, Michigan • Ferndale, Michigan • Mount Clemens, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Sep 17, 2026, 6:42 PM EDT
Completed Not applicable Interventional

Improving Well-Being After TBI Through Structured Volunteer Activity

NCT01728350
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
HOPE - Helping Others through Purpose and Engagement
Behavioral
Lead sponsor
Craig Hospital
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Englewood, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 29, 2018 · Synced Sep 17, 2026, 6:42 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

The HOPE Study: Characterizing Patients With Hepatitis B and C

NCT02995252
View directory record Official record
Conditions
Hepatitis B， Chronic, Hepatitis C
Interventions
Blood draws, Tenofovir Alafenamide, Knowledge Index Questionnaire, Liver transient elastography (FibroScan), Liver Biopsy
Other · Drug · Procedure
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 99 Years
Enrollment
550 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2034
U.S. locations
2
States / cities
Baltimore, Maryland • Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 17, 2026, 6:42 PM EDT
Withdrawn No phase listed Observational

Bronchiectasis: Evaluation of an Educational Intervention

NCT01315626
View directory record Official record
Conditions
Bronchiectasis
Interventions
Primary Care Educational event
Other
Lead sponsor
Hill-Rom
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Shelbyville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 17, 2015 · Synced Sep 17, 2026, 6:42 PM EDT
Not yet recruiting Not applicable Interventional

Developing a Recovery-Oriented Suicide Prevention Program for Young People at Clinical High Risk for Psychosis

NCT07756567
View directory record Official record
Conditions
Clinical High Risk for Psychosis (CHR), Suicidal Ideation, Psychosis, Suicidal Behavior
Interventions
Suicide Prevention Intervention, Standard Care (in control arm)
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
12 Years to 30 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Los Angeles, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 17, 2026, 6:42 PM EDT
Enrolling by invitation Not applicable Interventional

Reducing the Duration of Untreated Psychosis in the United States: The Impact of Screening and Systematic Communication

NCT05509998
View directory record Official record
Conditions
First Episode Psychosis (FEP), Clinical High Risk for Psychosis (CHR)
Interventions
Screening Method (SM), Screening and Communication Method (SCM)
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
12 Years to 30 Years
Enrollment
912 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 19, 2025 · Synced Sep 17, 2026, 6:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Does Enhancing Maternal Peer Interactions Decrease Rates of Postpartum Depression?

NCT03793569
View directory record Official record
Conditions
Postpartum Depression
Interventions
Peer discussion group
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 21, 2019 · Synced Sep 17, 2026, 6:42 PM EDT
Completed Not applicable Interventional

Harnessing Online Peer Education Opioid Study

NCT05814315
View directory record Official record
Conditions
Medication Compliance, Pain
Interventions
HOPE Intervention
Behavioral
Lead sponsor
ElevateU
Industry
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Corona del Mar, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Sep 17, 2026, 6:42 PM EDT
Completed Not applicable Interventional

Behavior and Activity Monitoring in MS

NCT03244696
View directory record Official record
Conditions
Relapsing-Remitting Multiple Sclerosis
Interventions
Step Tracking, Water Tracking
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
30 Years to 59 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Sep 17, 2026, 6:42 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Project humAn dieTary daTa rEtuRN

NCT06266689
View directory record Official record
Conditions
Diet Habit
Interventions
Personalized Diet Information
Behavioral
Lead sponsor
Duke University
Other
Eligibility
Up to 12 Months
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Sep 17, 2026, 6:42 PM EDT
Completed Not applicable Interventional Results available

HOPE Pilot for Veterans With Complex Diabetes

NCT01274715
View directory record Official record
Conditions
Diabetes, Depression
Interventions
Behavioral Health Coaching
Behavioral
Lead sponsor
Michael E. DeBakey VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 7, 2014 · Synced Sep 17, 2026, 6:42 PM EDT
Completed Not applicable Interventional

Single Session Intervention to Promote Hope

NCT06375876
View directory record Official record
Conditions
Domestic Violence
Interventions
Single-session intervention (SSI)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 17, 2026, 6:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brief Mindfulness Intervention for Patients at a Free Acute Care Clinic

NCT07025161
View directory record Official record
Conditions
Pain
Interventions
Pain Coping Information, Mindful Pain Management
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 17, 2026, 6:42 PM EDT