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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Habitual Lens Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Performance Evaluation of Two Daily Disposable Toric Lens Designs in Habitual Soft Contact Lens Wearers

NCT04831515
View directory record Official record
Conditions
Astigmatism
Interventions
Lens A, Lens B
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
4
States / cities
Whittier, California • Sarasota, Florida • Vestal, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2022 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Etafilcon A Contact Lenses Using a Novel Molding Process 2

NCT03701516
View directory record Official record
Conditions
Myopia
Interventions
etafilcon A with novel molding process, etafilcon A with current molding process
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
268 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
12
States / cities
Rocklin, California • Fleming Island, Florida • Jacksonville, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2022 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Phase 4 Interventional Results available

Lifitegrast 5% for the Treatment of Dry Eye In Habitual Soft Contact Lens Wearers

NCT05505292
View directory record Official record
Conditions
Dry Eye
Interventions
Lifitegrast 5% Ophthalmic Solution, Lifitegrast Ophthalmic Solution Vehicle
Drug · Other
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

One Month Dispensing Study Comparing the Clinical Performance of the Comfilcon A Sphere Lenses Compared to Comfilcon A Asphere Lenses.

NCT02759471
View directory record Official record
Conditions
Myopia
Interventions
comfilcon A sphere lens (control), comfilcon A asphere lens (test)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 34 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
4
States / cities
Whittier, California • Medina, Minnesota • Vestal, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Senofilcon A Contact Lenses Using a Novel Manufacturing Technology

NCT04531241
View directory record Official record
Conditions
Visual Acuity
Interventions
ACUVUE® OASYS 1-DAY
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
7
States / cities
Jacksonville, Florida • Maitland, Florida • Tallahassee, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 13, 2021 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Design Validation of Toric Contact Lenses in Senofilcon A With a Blue-Blocking Chromophore

NCT05778786
View directory record Official record
Conditions
Visual Acuity
Interventions
Acuvue Oasys 1 Day for Astigmatism, TRA100/TRA200 series toric contact lens with HEVL-blocking chromophore
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
188 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
10
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 16, 2024 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Results available

Multicenter Dispensing Study of Biofinity Toric Made-To-Order Lenses in Extended Power Ranges

NCT02193178
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
comfilcon A Toric
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Bloomington, Indiana • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Sep 10, 2026, 5:57 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers Results available

Tear Evaluation Between Habitual Contact Lens Wearers and Non Contact Lens Wearers

NCT01317030
View directory record Official record
Conditions
Dry Eye
Interventions
Contact Lens Wear, Non-Contact Lens Wear
Device · Other
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 8, 2020 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Marketed Soft Contact Lenses

NCT05201807
View directory record Official record
Conditions
Visual Acuity
Interventions
Dailies Total 1 (DT1)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
4
States / cities
Roswell, Georgia • Westerville, Ohio • Tyler, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 14, 2023 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Etafilcon A Contact Lenses Using a Novel Manufacturing Technology

NCT03962790
View directory record Official record
Conditions
Visual Acuity
Interventions
1-DAY ACUVUE® MOIST
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
6
States / cities
Maitland, Florida • Bloomington, Illinois • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2020 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Clinical Investigation of Visual Acuity in Contact Lens Wearers After Instillation of a Lipid- Based Lubricating Eye Drop

NCT06131476
View directory record Official record
Conditions
Visual Acuity
Interventions
Blink® Tears eye drops, Investigational lipid eye drops
Drug
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 69 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
2
States / cities
Jacksonville, Florida • Saint Augustine, Florida
Source: ClinicalTrials.gov public record
Updated Jun 25, 2024 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Short-Term Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions

NCT01240122
View directory record Official record
Conditions
Corneal Staining
Interventions
Biotrue MPS, Investigational MPS
Device
Lead sponsor
Abbott Medical Optics
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Santa Ana, California
Source: ClinicalTrials.gov public record
Updated Mar 2, 2025 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Performance of Different Daily Disposable Lens Designs in Habitual Soft Contact Lens Wearers

NCT04668989
View directory record Official record
Conditions
Myopia
Interventions
stenfilcon A - (Test lens), kalifilcon A - (Control Lens)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
4
States / cities
Medina, Minnesota • Vestal, New York • Athens, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 15, 2021 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing the Performance of 1 Day Multifocal Contact Lenses

NCT04449263
View directory record Official record
Conditions
Presbyopia
Interventions
Lens A, Lens B, Habitual Lenses
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
42 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
5
States / cities
San Diego, California • Whittier, California • Sarasota, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2021 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Wear Experience With One Week Reusable Contact Lenses in Habitual Two Week Reusable Lens Wearers

NCT06382064
View directory record Official record
Conditions
Myopia
Interventions
Biweekly replacement contact lenses, One week replacement contact lenses
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Results available

A Multi-Center Investigation of Patient Acceptability of OPTI-FREE RepleniSH® Multi-Purpose Disinfecting Solution (MPDS)

NCT00772707
View directory record Official record
Conditions
Myopia
Interventions
Multi-Purpose Disinfecting Solution (OPTI-FREE RepleniSH), Contact Lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 65 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Sep 6, 2012 · Synced Sep 10, 2026, 5:57 PM EDT
Terminated Not applicable Interventional Results available

Multifocal Visual Performance Study

NCT03757039
View directory record Official record
Conditions
Presbyopia
Interventions
Multifocal soft contact lenses, Progressive addition lens spectacles
Device · Other
Lead sponsor
Alcon Research
Industry
Eligibility
38 Years to 58 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2020 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Results available

Effect of an Investigational Multi-Purpose Solution on Lens Moisture

NCT01341990
View directory record Official record
Conditions
Contact Lens Moisture
Interventions
FID 114675A Multi-Purpose Disinfecting Solution (MPDS), ReNu Fresh Lens Comfort Multi-Purpose Solution (MPS), Silicone Hydrogel Contact Lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Apr 12, 2012 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility Evaluation of Daily Disposable Toric Soft Contact Lenses Manufactured With an Alternative Hydration Process

NCT05427539
View directory record Official record
Conditions
Ocular Physiology
Interventions
TEST LENS, CONTROL LENS
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
6
States / cities
Jacksonville, Florida • Maitland, Florida • Vestal, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2023 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Two Silicone Hydrogel Multifocal Contact Lenses

NCT04093258
View directory record Official record
Conditions
Visual Acuity
Interventions
Dailies Total 1® Multifocal Contact Lenses, Air Optix® Multifocal Contact Lenses Plus HydraGlyde®
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
3
States / cities
Roswell, Georgia • Granville, Ohio • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 30, 2021 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional

Clinical Evaluation of the Causes of Contact Lens Related Dry Eye

NCT00995189
View directory record Official record
Conditions
Contact Lens Related Dry Eye
Interventions
Opti-Free RepleniSH, ReNu MultiPlus, Contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Nov 16, 2016 · Synced Sep 10, 2026, 5:57 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Refitting Satisfied INFUSE One-Day Multifocal Wearers to DAILIES TOTAL1 Multifocal Contact Lenses

NCT07638943
View directory record Official record
Conditions
Contact Lens Comfort and Successful Refitting, Presbyopia
Interventions
DAILIES TOTAL1 Multifocal (delefilcon A)
Device
Lead sponsor
Gordon Schanzlin New Vision
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 10, 2026, 5:57 PM EDT
Completed No phase listed Observational Results available

Performance of Dailies Total1® Contact Lenses for Astigmatism in Symptomatic Habitual Reusable Toric Lens Wearers

NCT05498649
View directory record Official record
Conditions
Astigmatism
Interventions
DT1fA
Device
Lead sponsor
Keith Wan
Other
Eligibility
18 Years to 38 Years
Enrollment
86 participants
Timeline
2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 10, 2026, 5:57 PM EDT
Completed Not applicable Interventional Results available

Performance Evaluation of Reusable Contact Lenses When Worn For One Month By Habitual Soft Contact Lens Wearers

NCT06098339
View directory record Official record
Conditions
Myopia, Hyperopia
Interventions
Lens A (fanfilcon A), Lens B (lotrafilcon B)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Ocoee, Florida • State College, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Sep 10, 2026, 5:57 PM EDT