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ClinicalTrials.gov public records Last synced Oct 3, 2026, 4:57 PM EDT

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Showing 49–72 of 92 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Habitual contact lenses Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Design Validation of Toric Contact Lenses in Senofilcon A With a Blue-Blocking Chromophore

NCT05778786
View directory record Official record
Conditions
Visual Acuity
Interventions
Acuvue Oasys 1 Day for Astigmatism, TRA100/TRA200 series toric contact lens with HEVL-blocking chromophore
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
188 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
10
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2024 · Synced Oct 3, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neurolens and Contact Lens Discomfort

NCT05801991
View directory record Official record
Conditions
Contact Lens Discomfort
Interventions
Neurolens, Placebo spectacle lens
Device
Lead sponsor
Southern California College of Optometry at Marshall B. Ketchum University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Fullerton, California
Source: ClinicalTrials.gov public record
Updated Apr 22, 2025 · Synced Oct 3, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Contact Lens Insertion and Removal in a Senior Subject Demographic

NCT03597178
View directory record Official record
Conditions
Visual Acuity
Interventions
senofilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
60 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 3, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Senofilcon A Contact Lenses Using a Novel Manufacturing Technology

NCT04531241
View directory record Official record
Conditions
Visual Acuity
Interventions
ACUVUE® OASYS 1-DAY
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
7
States / cities
Jacksonville, Florida • Maitland, Florida • Tallahassee, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 14, 2021 · Synced Oct 3, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Marketed Soft Contact Lenses

NCT05201807
View directory record Official record
Conditions
Visual Acuity
Interventions
Dailies Total 1 (DT1)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
4
States / cities
Roswell, Georgia • Westerville, Ohio • Tyler, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 15, 2023 · Synced Oct 3, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Senofilcon A With New UV-blocker on a Neophyte Population

NCT03742271
View directory record Official record
Conditions
Visual Acuity
Interventions
senofilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
11
States / cities
Jacksonville, Florida • Jacksonville Beach, Florida • Longwood, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Mar 13, 2020 · Synced Oct 3, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Wear Experience With a Water Surface Daily Disposable Contact Lens

NCT05102383
View directory record Official record
Conditions
Contact Lens
Interventions
Comfilcon A Toric contact lenses, Verofilcon A for Astigmatism Daily Disposable contact lenses
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Oct 3, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of ACUVUE® OASYS 1-Day for Astigmatism Contact Lenses With Alternative Lidstock

NCT05713552
View directory record Official record
Conditions
Ocular Physiology
Interventions
Acuvue Oasys 1 Day for Astigmatism with Legacy lidstock, Acuvue Oasys 1 Day for Astigmatism with Amcor laminated lidstock
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 5, 2024 · Synced Oct 3, 2026, 4:57 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

UNITY DX Cornea Study

NCT07768735
View directory record Official record
Conditions
Tomography
Interventions
UNITY DX, ANTERION
Device
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 3, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Dryness in a Silicone Hydrogel Daily Disposable Contact Lens

NCT04849780
View directory record Official record
Conditions
Visual Acuity
Interventions
ACUVUE Oasys 1-Day, Habitual Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 59 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
9
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 10, 2022 · Synced Oct 3, 2026, 4:57 PM EDT
Withdrawn Not applicable Interventional

OPTI-FREE Family STUDY

NCT06592521
View directory record Official record
Conditions
Contact Lens Care
Interventions
OPTI-FREE EXPRESS MPDS and Alcon contact lens case, OPTI-FREE PureMoist MPDS and Alcon contact lens case, OPTI-FREE REPLENISH MPDS and Alcon contact lens case, Habitual contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
7 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Oct 3, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Two Silicone Hydrogel Multifocal Contact Lenses

NCT04093258
View directory record Official record
Conditions
Visual Acuity
Interventions
Dailies Total 1® Multifocal Contact Lenses, Air Optix® Multifocal Contact Lenses Plus HydraGlyde®
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
3
States / cities
Roswell, Georgia • Granville, Ohio • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 1, 2021 · Synced Oct 3, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Comfort for Two Marketed Daily Disposable Contact Lenses

NCT04968925
View directory record Official record
Conditions
Visual Acuity
Interventions
ACUVUE Oasys 1-Day, Precision 1
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
302 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
10
States / cities
Mission Viejo, California • Maitland, Florida • Orange Park, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Dec 22, 2022 · Synced Oct 3, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effects of Contact Lenses With UV/HEV-Filter on Visual Function

NCT05601544
View directory record Official record
Conditions
Visual Acuity
Interventions
ACUVUE OASYS 1-Day, ACUVUE OASYS MAX 1-Day, ACUVUE OASYS Multifocal, ACUVUE OASYS MAX 1-Day Multifocal, ACUVUE OASYS 1-Day for Astigmatism, senofilcon A based contact lens (toric) with new UV/HEV filter
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 27, 2025 · Synced Oct 3, 2026, 4:57 PM EDT
Completed Not applicable Interventional Results available

A Multi-Center Investigation of Patient Acceptability of OPTI-FREE RepleniSH® Multi-Purpose Disinfecting Solution (MPDS)

NCT00772707
View directory record Official record
Conditions
Myopia
Interventions
Multi-Purpose Disinfecting Solution (OPTI-FREE RepleniSH), Contact Lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 65 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Sep 7, 2012 · Synced Oct 3, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ocular Characteristics in Contact Lens and Spectacle Wear

NCT03913377
View directory record Official record
Conditions
Visual Acuity
Interventions
Spectacles, ACUVUE OASYS®1-Day with HydraLuxe™ Technology
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 42 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
3
States / cities
Jacksonville, Florida • Longwood, Florida • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 4, 2021 · Synced Oct 3, 2026, 4:57 PM EDT
Completed Not applicable Interventional Results available

Assessing Fitting Guides in Alcon Multifocal Contact Lenses

NCT03118934
View directory record Official record
Conditions
Presbyopia, Refractive Errors
Interventions
Lotrafilcon B multifocal contact lenses, Nelfilcon A multifocal contact lenses, Delefilcon A multifocal contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years to 65 Years
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
14
States / cities
Phoenix, Arizona • San Diego, California • Pensacola, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Sep 26, 2018 · Synced Oct 3, 2026, 4:57 PM EDT
Recruiting Not applicable Interventional

Comparison of Hand Eye Coordination and Sports Vision Performance in Dual-Focus Multifocal Contact Lenses and Habitual Contact Lenses

NCT07840209
View directory record Official record
Conditions
Myopia
Interventions
Multifocal Contact Lens
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 38 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 3, 2026, 4:57 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Pilot Clinical Evaluation of Approved Contact Lenses

NCT02540122
View directory record Official record
Conditions
Vision Disorders
Interventions
Marketed Contact Lens 1, Marketed Contact Lens 2, Marketed Contact Lens 3, Marketed Contact Lens 4
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 20, 2017 · Synced Oct 3, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Senofilcon A Contact Lenses Using a Novel Manufacturing Technology to Evaluate Overall Visual Acuity.

NCT05361304
View directory record Official record
Conditions
Visual Acuity
Interventions
senofilcon A contact lenses made with a novel manufacturing technology, senofilcon A contact lenses made with the current manufacturing technology
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
6
States / cities
Jacksonville, Florida • Orange Park, Florida • Tallahassee, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2023 · Synced Oct 3, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Role of Glare and Spectral Filtering on Contrast Sensitivity: A Pilot Study

NCT05582304
View directory record Official record
Conditions
Visual Acuity
Interventions
Test Lens, Control Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Oct 3, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Performance Evaluation of Two Silicone Hydrogel Toric Lens Designs in Habitual Soft Contact Lens Wearers

NCT05933772
View directory record Official record
Conditions
Astigmatism
Interventions
Lens A (comfilcon A toric lens), Lens B (lehfilcon A toric lens)
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years to 39 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
3
States / cities
Pittsburg, Kansas • Vestal, New York • Granville, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Oct 3, 2026, 4:57 PM EDT
Completed Not applicable Interventional Results available

Multicenter Dispensing Study of Biofinity Toric Made-To-Order Lenses in Extended Power Ranges

NCT02193178
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
comfilcon A Toric
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Bloomington, Indiana • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2020 · Synced Oct 3, 2026, 4:57 PM EDT
Completed Not applicable Interventional Results available

Subjective Comfort With Multipurpose Care Solutions in Soft Contact Lens Wearers

NCT01211535
View directory record Official record
Conditions
Myopia, Astigmatism, Refractive Error
Interventions
OPTI-FREE RepleniSH multipurpose solution, ReNu Biotrue multipurpose solution, Silicone hydrogel contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Nov 12, 2012 · Synced Oct 3, 2026, 4:57 PM EDT