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Showing 1–24 of 32 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Hand orthosis Clear all
Completed Not applicable Interventional Results available

Glove Rehabilitation Application for Stroke Patients

NCT03872466
View directory record Official record
Conditions
Occupational Therapy, Virtual Reality
Interventions
GRASP HEP, Usual Care Treatment (UCT)
Device · Behavioral
Lead sponsor
Barron Associates, Inc.
Industry
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 24, 2025 · Synced Sep 5, 2026, 2:15 PM EDT
Terminated Not applicable Interventional

Chronic Stroke Rehabilitation With Contralesional Brain-Computer Interface

NCT03611855
View directory record Official record
Conditions
Chronic Stroke, Hemiparesis
Interventions
BCI Rehabilitation, Range of Motion Therapy
Device · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 85 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 18, 2021 · Synced Sep 5, 2026, 2:15 PM EDT
Completed Not applicable Interventional

Case Series_Targeted Training for Trunk Control Cerebral Palsy

NCT02246751
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Targeted Training for trunk control
Device
Lead sponsor
University of Hartford
Other
Eligibility
2 Years to 12 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
West Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 6, 2020 · Synced Sep 5, 2026, 2:15 PM EDT
Completed Not applicable Interventional Results available

Robotics For Rehabilitation Therapy: Functional Versus Individual Joint Training

NCT01050231
View directory record Official record
Conditions
Cerebrovascular Accident
Interventions
Functional/ Multi-joints activities, Individual Joint Training
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 73 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Apr 18, 2021 · Synced Sep 5, 2026, 2:15 PM EDT
Completed No phase listed Observational

Evaluating Human-Machine Interfaces in a Robotic Thumb Orthosis

NCT01973426
View directory record Official record
Conditions
Hemiplegic Stroke, Hemiplegic Cerebral Palsy
Interventions
Isolated Orthosis for Thumb Actuation (IOTA)
Device
Lead sponsor
Wyss Institute at Harvard University
Other
Eligibility
7 Years to 16 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 8, 2020 · Synced Sep 5, 2026, 2:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Hand Assistive Rehabilitation Orthotic Device Effectiveness Study

NCT04565639
View directory record Official record
Conditions
Orthoses, Prostheses
Interventions
Powered Hand Orthosis
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
18 Years to 89 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Holliston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 24, 2020 · Synced Sep 5, 2026, 2:15 PM EDT
Completed No phase listed Observational

Retrospective Study on Myoelectric Elbow-Wrist-Hand Orthosis User Outcomes

NCT05575674
View directory record Official record
Conditions
Stroke, Brachial Plexus Injury, Spinal Cord Injuries, Neurological Disease
Interventions
Myoelectric Elbow-Wrist-Hand Orthosis
Device
Lead sponsor
Myomo
Industry
Eligibility
65 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
3
States / cities
Boston, Massachusetts • Chardon, Ohio • Edmonds, Washington
Source: ClinicalTrials.gov public record
Updated Oct 9, 2023 · Synced Sep 5, 2026, 2:15 PM EDT
Terminated Not applicable Interventional Results available

FAME: Functional Assessment of a Myoelectric Orthosis Hand Orthoses

NCT04266158
View directory record Official record
Conditions
Paresis, Stroke
Interventions
Myoelectric UE Device-UE Orthosis-No Device
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 85 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 10, 2022 · Synced Sep 5, 2026, 2:15 PM EDT
Completed Not applicable Interventional Results available

Myoelectric Upper Limb Orthosis Use by Persons With TBI and Stroke

NCT03215771
View directory record Official record
Conditions
Traumatic Brain Injury, Stroke
Interventions
MyoPro Motion-G, Motor Learning-Based Therapy
Device · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 14, 2021 · Synced Sep 5, 2026, 2:15 PM EDT
Completed Not applicable Interventional Results available

Wireless Prosthetic Control Effectiveness Study

NCT06821412
View directory record Official record
Conditions
Prostheses, Upper Limb Amputation Below Elbow
Interventions
ASTERISK System, Wired Configuration
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
18 Years to 89 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Holliston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Sep 5, 2026, 2:15 PM EDT
Not listed Not applicable Interventional

Psychosocial Factors a Prognostic Study of Pain in Patients With CMC Osteoarthritis

NCT03821298
View directory record Official record
Conditions
Pain, Osteoarthritis
Interventions
Standard of Care Hand Therapy
Other
Lead sponsor
Gannon University
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Ruskin, Florida
Source: ClinicalTrials.gov public record
Updated Jul 30, 2019 · Synced Sep 5, 2026, 2:15 PM EDT
Completed Not applicable Interventional

A User-friendly, Non-invasive Neuro-orthosis That Restores Volitionally Controlled Grasp Functions for SCI Survivors With Tetraplegia

NCT06087445
View directory record Official record
Conditions
Cervical Spinal Cord Injury
Interventions
NeuroLife EMG-FES Sleeve System
Device
Lead sponsor
Ohio State University
Other
Eligibility
22 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 5, 2026, 2:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Comparison Study of Three Standard Elbow Wrist Hand Orthoses to Limit Forearm Rotation

NCT04130425
View directory record Official record
Conditions
Healthy
Interventions
Hely & Weber MTC Fracture Brace, Thermoplastic orthosis, Delta cast orthosis
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 100 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 30, 2020 · Synced Sep 5, 2026, 2:15 PM EDT
Recruiting No phase listed Observational

3D Printed Orthosis for Wrist Instability for Ehlers-Danlos Syndrome Patient

NCT07565636
View directory record Official record
Conditions
Ehlers-Danlos Syndrome Hypermobility Type (hEDS)
Interventions
3D scanned and 3D printed wrist hand orthosis
Device
Lead sponsor
ELewis
Other
Eligibility
21 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Lowell, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Sep 5, 2026, 2:15 PM EDT
Recruiting Not applicable Interventional

Exoskeleton Research: Myoelectric Orthosis for Rehab of Severe Chronic Arm Motor Deficits

NCT05296408
View directory record Official record
Conditions
Chronic Stroke
Interventions
motor learning based therapy, MyoPro, Home Exercise Program
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 5, 2026, 2:15 PM EDT
Completed No phase listed Observational

Saeboflex Dynamic Hand Orthosis for Inpatient Rehabilitation Stroke Patients

NCT00485641
View directory record Official record
Conditions
Stroke
Interventions
SaeboFlex Dynamic Hand Orthosis, Saebo F.T.M. Arm Training Program
Device · Procedure
Lead sponsor
Kessler Foundation
Other
Eligibility
Not listed
Enrollment
222 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
3
States / cities
Chester, New Jersey • East Orange, New Jersey • Saddle Brook, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 12, 2007 · Synced Sep 5, 2026, 2:15 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Influence of Exercise Type, Pain Mechanisms, and Biopsychosocial Contributions to Pain Relief in Those With Fibromyalgia

NCT03778385
View directory record Official record
Conditions
Fibromyalgia
Interventions
Exercise
Other
Lead sponsor
Marquette University
Other
Eligibility
18 Years to 75 Years
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 6, 2022 · Synced Sep 5, 2026, 2:15 PM EDT
Not listed Not applicable Interventional

Novel Splinting Technique Using 3D Models

NCT05351060
View directory record Official record
Conditions
Arthritis, Osteoarthritis Hand, Scleroderma, Systemic, Scleroderma, Diffuse, Rheumatoid Arthritis
Interventions
Custom Fabricated Splint
Other
Lead sponsor
Giovanna Fichera
Other
Eligibility
18 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Troy, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Sep 5, 2026, 2:15 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

MyHand-SCI: An Active Hand Orthosis for Spinal Cord Injury

NCT05553457
View directory record Official record
Conditions
Spinal Cord Injuries, Tetraplegia
Interventions
Testing of MyHand-SCI Device
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 5, 2026, 2:15 PM EDT
Completed Not applicable Interventional Results available

A Pilot Randomized Controlled Trial for Hand Osteoarthritis

NCT04784065
View directory record Official record
Conditions
Hand Osteoarthritis
Interventions
Hand orthosis
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Not listed
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
New York, New York • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Sep 5, 2026, 2:15 PM EDT
Not listed Early Phase 1 Interventional

Combining Wearable Robotic Orthosis With Visual and Haptic Feedback to Enhance the Recovery of Upper Extremity Motor Function and ADL in Persons With Acute SCI

NCT05386537
View directory record Official record
Conditions
SCI - Spinal Cord Injury
Interventions
MyoMo orthosis and VR games, MyoPro robot only, Games only, Control
Combination Product · Device · Other
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated May 5, 2023 · Synced Sep 5, 2026, 2:15 PM EDT
Completed Not applicable Interventional Results available

Robotic Hand Orthosis Providing Grasp Assistance for Patients With Brachial Plexus Injuries

NCT04939233
View directory record Official record
Conditions
Brachial Plexus Injury
Interventions
Exoskeleton glove
Device
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 69 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Sep 5, 2026, 2:15 PM EDT
Not listed No phase listed Observational

Outcome Measures Study on an Adult Myoelectric Elbow-Wrist-Hand Orthosis

NCT04900896
View directory record Official record
Conditions
Stroke, Brachial Plexus Injury, Spinal Cord Injuries, Neurological Disease
Interventions
Myoelectric Elbow-Wrist-Hand Orthosis
Device
Lead sponsor
Myomo
Industry
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
3
States / cities
Boston, Massachusetts • Chardon, Ohio • Edmonds, Washington
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Sep 5, 2026, 2:15 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Effectiveness of Splinting After Collagenase Injection

NCT04874870
View directory record Official record
Conditions
Dupuytren Contracture, Dupuytren's Disease
Interventions
Collagenase Clostridium Histolyticum 0.9 MG [Xiaflex], Xiaflex + Hand-Based Custom Orthosis
Drug · Combination Product
Lead sponsor
Foundation for Orthopaedic Research and Education
Other
Eligibility
18 Years to 90 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Sep 5, 2026, 2:15 PM EDT