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Conditions: Obesity
Interventions: Behavioral Treatment, Placebo, Semaglutide 2.4 MG/0.75 ML Subcutaneous Solution [WEGOVY]; Behavioral · Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 70 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Obesity
Interventions: Lifestyle Counseling; Behavioral
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 20 Years to 75 Years
Enrollment: 803 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Cardiac Rehabilitation
Interventions: Referral to home-based cardiac rehab, Referral to center-based cardiac rehab; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 1,154 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Type 2 Diabetes
Interventions: Digital Health Coaching, Continuous Glucose Monitoring Teleconsults; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 89 Years
Enrollment: 5,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Recurrent Prostate Cancer, Stage IV Prostate Cancer
Interventions: behavioral dietary intervention, exercise intervention, behavioral activity counseling, telephone based counseling, quality-of-life assessment, questionnaire administration; Behavioral · Other · Procedure
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: Male only
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Type 2 Diabetes
Interventions: E3 Multidisciplinary Team, E3 Self-Guided Type 2 Diabetes Education; Behavioral
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Hypertension, Colon Cancer
Interventions: MINT, Patient Navigation; Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 50 Years and older · Male only
Enrollment: 740 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: New York, New York

Conditions: Post Liver Transplantation Weight Gain, Post Liver Transplantation Obesity, Nonalcoholic Steatohepatitis
Interventions: Dietary and life style modification; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2008
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Childhood Obesity, Overweight, Communication, Weight Loss
Interventions: Communication regarding overweight status, Risk-factor assessment and counseling, Lifestyle behavior assessment and counseling, Interval follow-up to readdress weight, Patient-centered communication; Other
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 6 Years to 12 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Chronic Obstructive Pulmonary Disease
Interventions: Physical activity self-management, COPD education + Usual care; Behavioral · Other
Lead sponsor: The University of Texas Health Science Center at Tyler; Other
Eligibility: 45 Years and older
Enrollment: 325 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Tyler, Texas

Conditions: Sedentary Lifestyle, Risk of Disability, Aging
Interventions: Physical Activity, Successful Aging; Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 70 Years to 89 Years
Enrollment: 1,635 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 8
States / cities: Palo Alto, California • New Haven, Connecticut • Gainesville, Florida + 5 more

Conditions: Type 2 Diabetes Mellitus
Interventions: Lifestyle Counseling, Educational Control Arm; Behavioral
Lead sponsor: East Carolina University; Other
Eligibility: 19 Years to 75 Years · Female only
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Greenville, North Carolina

Conditions: Prostate Carcinoma, Recurrent Prostate Carcinoma
Interventions: Antiandrogen Therapy, Behavioral Intervention, Biospecimen Collection, Cardiac Computerized Tomographic Angiography, Computed Tomography, Electronic Health Record Review, Internet-Based Intervention, Lifestyle Counseling, Medical Device Usage and Evaluation, Nutritional Intervention, Questionnaire Administration, Radiation Therapy, Referral, Semaglutide, Short-Term Fasting, Tirzepatide; Drug · Behavioral · Procedure + 2 more
Lead sponsor: City of Hope Medical Center; Other
Eligibility: 30 Years to 79 Years · Male only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Duarte, California

Conditions: Autism Spectrum Disorder, Obesity
Interventions: Glucagon-like peptide-1 receptor agonist：Semaglutide, Lifestyle Management (LSM) Counseling; Drug · Behavioral
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 12 Years to 18 Years
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Smoking, Motivation, Smoking Cessation
Interventions: Nicotine Mini-Lozenge, Behavioral Reduction Counseling, 5Rs Motivation Counseling, Behavioral Activation Counseling, No Treatment; Drug · Behavioral · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 577 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Chronic Pain, Mild Cognitive Impairment, Older Adults, Physical Activity
Interventions: Active Brains 1, Active Brains 2; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 60 Years and older
Enrollment: 267 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Type 2 Diabetes Mellitus
Interventions: Intensive Lifestyle Intervention; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Cardiovascular Diseases, Heart Diseases, Obesity
Interventions: Single behavior intervention, Multiple behavior interventions, Control Intervention unrelated to weight; Behavioral
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 8 Years to 12 Years
Enrollment: 158 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2015
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Chronic Pain, Mild Cognitive Impairment, Older Adults, Physical Activity
Interventions: Active Brains 1, Active Brains 2; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 60 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Smoking Cessation, Obesity
Interventions: Self-Regulation strategies + large changes (SR), Healthy Lifestyle Education (LE), Smoking Cessation Treatment; Behavioral · Other
Lead sponsor: Brown University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 55 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Diabetes Mellitus, Type 2
Interventions: Counseling; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 65 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Impoverished Population
Interventions: Self-Care Stimulating Disease Prevention Program (SCSDPP), Stand procedures, no intervention; Behavioral · Other
Lead sponsor: Jonsson Comprehensive Cancer Center; Other
Eligibility: 18 Years to 120 Years
Enrollment: 97 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2022
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: HIV
Interventions: MEN Count, Comparison; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 40 Years · Male only
Enrollment: 455 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Weight Loss
Interventions: RCT1, RCT2, RCT3; Behavioral
Lead sponsor: RTI International; Other
Eligibility: 18 Years to 64 Years
Enrollment: 2,395 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 3
States / cities: Swansea, Illinois • Research Triangle Park, North Carolina • Fairborn, Ohio

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Semaglutide Treatment, Appetite, and Eating Behavior: Long-term Effects

Promoting Successful Weight Loss in Primary Care in Louisiana

The Healthy Heart Study

Advancing Diabetes Management for People With Physical Disabilities Optimally Through Primary Care-Based Telehealth (ADDOPT)

Intensive Diet and Exercise or Standard of Care in Improving Physical Function and Quality of Life in Patients With Prostate Cancer Undergoing Androgen Deprivation Therapy

E3 Diabetes - Closing the Gap in Diabetes Control

Community-based Approaches to Treating Hypertension and Colon Cancer Prevention

Effect of Dietary and Life Style Modification on Post Liver Transplant Obesity

Primary Care, Communication, and Improving Children's Health

Randomized Trial of Physical Activity Self-Management Intervention for Patients With COPD

The LIFE Study - Lifestyle Interventions and Independence for Elders

Empowering Rural African American Women and Communities to Improve Diabetes Outcomes

Metabolic Interventions (Time-Restricted Eating, GLP1 Receptor Agonist, and Heart Healthy Diet) to Improve Cardiometabolic Health in Prostate Cancer Patients During Androgen Deprivation Therapy, IMPACT-ADT Trial

Semaglutide in Youth With Autism Spectrum Disorder

Motivation Project: Testing Intervention Components for the Smoker Who is Unwilling to Quit

Managing Pain and Cognitions in Older Adults With Early Cognitive Decline and Chronic Pain

Changing Lifestyles for Better Health

Behavior Change Family Counseling to Reduce Rate of Weight Gain in At-Risk Children

Managing Pain and Cognitions in Older Adults With Mild Cognitive Impairment or Memory Related Problems and Chronic Pain

A Multiple Health Behavior Change Intervention for Overweight and Obese Smokers

Lifestyle Intervention for Adults With Diabetes

Patient-Directed Lifestyle Change and Health Promotion Program or Usual Care in Low-Income, Uninsured Participants in Los Angeles County, California

Evaluating a Structural and Behavioral HIV Risk Reduction Program for Black Men

Weight Management Demonstration Project: HEALTH