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Conditions: Chest Pain, Acute Coronary Syndrome, Acute Myocardial Infarction, Coronary Artery Disease
Interventions: CT Coronary Angiography (CTCA), Traditional Strategy; Diagnostic Test · Procedure
Lead sponsor: American College of Radiology; Other
Eligibility: 30 Years and older
Enrollment: 1,392 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 5
States / cities: Winston-Salem, North Carolina • Hershey, Pennsylvania • Philadelphia, Pennsylvania + 1 more

Conditions: Multiple Myeloma
Interventions: Planned Notification, Survey Administration, Behavioral Intervention, Electronic Health Record Review, Interview; Other · Behavioral
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years and older
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Geriatric Disorder, Cancer, Patient Fall
Interventions: Stepping On Education Program, Home visit, Patient Questionnaire, Mini-Balance Evaluation Systems Test, GAITRite, Precise measure of movement testing; Other
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 70 Years and older
Enrollment: 101 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Treatment Resistant Depression
Interventions: Moderate Intensity Aerobic Exercise, Wait-list; Other
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Employee Health and Well-being
Interventions: Workplace Wellness Program, Biometric Screening/HRA - No Compensation, Biometric Screening/HRA - Moderate Compensation, Biometric Screening/HRA - High Compensation, Wellness Activities - Low Compensation, Wellness Activities - High Compensation; Behavioral
Lead sponsor: National Bureau of Economic Research, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 4,834 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Colorectal Cancer, Bladder Cancer, Ovarian Cancer, Cervical Cancer, Uterine Cancer
Interventions: Patient-Reported Outcomes-Informed Symptom Management System (PRISMS); Behavioral
Lead sponsor: UNC Lineberger Comprehensive Cancer Center; Other
Eligibility: 18 Years to 99 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Obesity, Diet Modification
Interventions: Dietary Counseling; Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 65 Years
Enrollment: 47 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Lung Cancer, Perioperative/Postoperative Complications, Pulmonary Complications, Tobacco Use Disorder
Interventions: exercise intervention, smoking cessation intervention, counseling intervention, educational intervention, conventional surgery, pulmonary complications management/prevention; Behavioral · Other · Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 40 Years to 120 Years
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Healthy
Interventions: Cognitive interview, Survey; Behavioral · Other
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 30 Years to 65 Years
Enrollment: 1,191 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Smoking, Tobacco, Fractures, Bone
Interventions: Motivational Interviewing, Motivational Interviewing + Follow-up; Behavioral
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 79 Years
Enrollment: 269 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Stress (Psychology), Inflamation, Psychosocial Functioning
Interventions: Building Emotional Strength Training; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Cancer
Interventions: Pain Buddy; Other
Lead sponsor: University of California, Irvine; Other
Eligibility: 8 Years to 18 Years
Enrollment: 407 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Orange, California

Conditions: Chronic Disease
Interventions: Text Messaging; Behavioral
Lead sponsor: Boston University; Other
Eligibility: 18 Years and older
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Adenovirus
Interventions: Brincidofovir, Standard of Care; Drug
Lead sponsor: Jazz Pharmaceuticals; Industry
Eligibility: 18 Years to 99 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 4
States / cities: Los Angeles, California • Chicago, Illinois • Boston, Massachusetts + 1 more

Conditions: Lung Carcinoma
Interventions: Educational Intervention, Exercise Intervention, Medical Device Usage and Evaluation, Physical Performance Testing, Quality-of-Life Assessment, Questionnaire Administration; Other
Lead sponsor: City of Hope Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 382 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2028
U.S. locations: 16
States / cities: Davis, California • Duarte, California • Irvine, California + 13 more

Conditions: Diabetic Foot, Quality of Life, Mental Health Wellness 1, Ulcer Foot, Diabetes Complications
Interventions: No intervention, this is an observational study; Other
Lead sponsor: Podimetrics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Somerville, Massachusetts

Conditions: Respiratory Insufficiency
Interventions: Music Therapy; Behavioral
Lead sponsor: Northwell Health; Other
Eligibility: Up to 18 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2023
U.S. locations: 1
States / cities: New Hyde Park, New York

Conditions: Nosocomial Infections
Interventions: 2% Chlorhexidine gluconate cloth; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 2 Months to 25 Years
Enrollment: 5,659 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 5
States / cities: Washington D.C., District of Columbia • Baltimore, Maryland • St Louis, Missouri + 2 more

Conditions: Squamous Cell Carcinoma, Human Papilloma Virus (HPV), Oropharyngeal Squamous Cell Carcinoma (OPSCC)
Interventions: Active Surveillance With ctHPVDNA (NavDx®); Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2034
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Chronic Low-back Pain, Catastrophizing Pain, Kinesiophobia
Interventions: Transcranial Direct Current Stimulation, Pain Neuroscience Education; Device · Behavioral
Lead sponsor: High Point University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: High Point, North Carolina

Conditions: Breast Carcinoma
Interventions: Electronic Health Record Review, Health Promotion and Education, Health Telemonitoring, Patient Navigation, Survey Administration, Text Message-Based Navigation Intervention; Other · Procedure · Behavioral
Lead sponsor: ECOG-ACRIN Cancer Research Group; Network
Eligibility: 18 Years and older
Enrollment: 390 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 499
States / cities: Fairbanks, Alaska • Kingman, Arizona • Phoenix, Arizona + 338 more

Conditions: Dementia
Interventions: Structured Retrieval Practice (SRP), Standard Health Education; Behavioral
Lead sponsor: Texas Christian University; Other
Eligibility: 18 Years and older
Enrollment: 73 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 2
States / cities: Fort Worth, Texas • Norfolk, Virginia

Conditions: Pelvic Organ Prolapse, Urinary Incontinence
Interventions: Patient reminder system; Other
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 162 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Coronary Heart Disease, Myocardial Infarction
Interventions: Titration of medications, Lifestyle Counseling, Medication Counseling, Usual Care with Medication Reconciliation; Other · Behavioral
Lead sponsor: Middle Tennessee Research Institute; Other
Eligibility: 60 Years to 90 Years
Enrollment: 170 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Nashville, Tennessee

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Computed Tomography Coronary Angiogram (CTCA) Versus Traditional Care in Emergency Department Assessment of Potential Acute Coronary Syndromes (ACS)

Two Implementation Strategies for the Collection of Electronic Patient-Reported Outcomes Among Patients With Multiple Myeloma

Adaptation of the STEPPING ON Fall Prevention Program for Older Adults Receiving Cancer Therapy

Exercise in Treatment Resistant Depression (TRD): A Feasibility Study

Illinois Workplace Wellness Study

Feasibility Testing of Patient Reported Outcomes - Informed Symptom Management System (PRISMS)

Metabolic Impact of Time Restricted Feeding

Lung Rehabilitation in Treating Patients With Chronic Obstructive Pulmonary Disease Who Are Undergoing Surgery for Lung Cancer

Communicating Multiple Disease Risks

Let's STOP Now Trial: Smoking in Trauma Orthopaedic Patients

A Mindfulness-Based Intervention to Reduce Stress Through the Cultivation of Loving-Kindness, Compassion, Joy, and Equanimity in Healthcare Professionals

Treating Pain in Children With Cancer: Pain Buddy

Self-Management Using Text Messaging in a Homeless Population

Open Label Study of IV Brincidofovir in Adult Transplant Recipients With Adenovirus Viremia

Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their Caregivers

Patient Empowerment Study

Music Therapy During Pediatric Extubation Readiness Trials

Study of Bathing With Chlorhexidine Impregnated Cloths on Nosocomial Infections in the Pediatric Intensive Care Unit

Omission of Postoperative Radiation in HPV-Associated Oropharyngeal Cancer Using ctHPVDNA Surveillance (OPERATION)

The Effect of Combining Pain Neuroscience Education and Transcranial Direct Current Stimulation on Pain Catastrophizing, Kinesiophobia, and Pain in Patients With Chronic Low Back Pain

Mobile Health for Adherence in Breast Cancer Patients

Learn About Caring for a Person Living With Dementia

Improving Uroflowmetry Interpretability: Evaluating the Impact of Patient Reminder Systems

Monitoring and Adjustment of Medication Therapy for Patients With Heart Disease