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ClinicalTrials.gov public records Last synced Oct 19, 2026, 2:02 AM EDT

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Showing 1–24 of 122 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Healthy Aging Intervention Clear all
Active, not recruiting Phase 3 Interventional

ACHIEVE Brain Health Follow-Up Study

NCT05532657
View directory record Official record
Conditions
Aging, Cognitive Decline, Mild Cognitive Impairment, Dementia, Hearing Loss
Interventions
Hearing intervention, Successful aging/delayed hearing intervention
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
73 Years and older
Enrollment
629 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
4
States / cities
Hagerstown, Maryland • Minneapolis, Minnesota • Jackson, Mississippi + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 19, 2026, 2:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prosocial Behavior and Volunteerism to Promote Physical Activity in Older Adults

NCT01528761
View directory record Official record
Conditions
Physical Activity
Interventions
Prosocial Behavior Physical Activity (PBPA), Healthy Aging (HA)
Behavioral · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
55 Years and older
Enrollment
317 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 14, 2018 · Synced Oct 19, 2026, 2:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Investigation of a Multinutrient Supplement on Skin Aging and Aging Metabolites in Healthy Women

NCT00541931
View directory record Official record
Conditions
Skin Diseases
Interventions
Dietary Supplement: LifePak Nano
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Nov 20, 2017 · Synced Oct 19, 2026, 2:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Enhancing Independence Using Group-based Community Interventions for Healthy AGing in Elders: the ENGAGE Pilot Study

NCT03430271
View directory record Official record
Conditions
Mobility Limitation
Interventions
Physical Activity Intervention, Healthy Aging Intervention
Other
Lead sponsor
Tufts University
Other
Eligibility
65 Years to 89 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts • Somerville, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 14, 2018 · Synced Oct 19, 2026, 2:02 AM EDT
Recruiting Not applicable Interventional

REmote Virtual Inspiration: Vitality and Energy

NCT07675681
View directory record Official record
Conditions
Implementation Science, Women Health, Disability Physical, Meditation, Tai Chi
Interventions
Accesible Tai Chi/Qigong (TCQ), Health Education Videos (HEV)
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
35 Years to 64 Years · Female only
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 19, 2026, 2:02 AM EDT
Completed Phase 2 Interventional

Social Connections and Healthy Aging (The Senior Connection)

NCT01408654
View directory record Official record
Conditions
Suicidal Ideation, Depression
Interventions
Peer Companionship
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
60 Years and older
Enrollment
368 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 22, 2016 · Synced Oct 19, 2026, 2:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sedentary Behavior Interrupted Randomized Controlled Trial (P2)

NCT03473145
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
Health Coaching, activPAL inclinometer, Tools to Prompt Standing or Prompt Sit-to-Stand Transitions.
Behavioral · Device · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
55 Years and older · Female only
Enrollment
407 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Oct 19, 2026, 2:02 AM EDT
Terminated Not applicable Interventional

Physical Exercise And Cognitive Engagement Outcomes for Mild Neurocognitive Disorder

NCT03095170
View directory record Official record
Conditions
Mild Cognitive Impairment, Memory Disorders, Mild Dementia, Impaired Cognition, Mild Cognitive Disorder, Amnestic Disorder, Dementia and Amnestic Conditions, Poor Short-term Memory, Memory Impairment, Mild Neurocognitive Disorder
Interventions
Computerized brain fitness training, Yoga, Wellness Education, Support Group (patient and partner), Cognitive Rehabilitation
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 6, 2022 · Synced Oct 19, 2026, 2:02 AM EDT
Not yet recruiting Phase 2 Interventional

Testing Heart Failure Resilience Intervention for Caregivers (HEROIC) in Advanced Heart Failure

NCT07805811
View directory record Official record
Conditions
Heart Failure, Caregiver
Interventions
HEROIC program, Active Comparator Control 1
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
2
States / cities
Denver, Colorado • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 19, 2026, 2:02 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

AMPLIFI: Adaptive Modulation of Plasticity Through Lactate and Fitness Interventions

NCT06950060
View directory record Official record
Conditions
Stroke, Chronic, Aging, Cognitive Decline, Motor Dysfunction, Neuroplasticity
Interventions
High intensity cycling, Low-intensity cycling, Health education session, Moderate Intensity Aerobic Exercise
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 85 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 19, 2026, 2:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Guided Episodic Future Thinking to Increase Physical Activity Adherence and Promote Healthy Brain Aging

NCT06123182
View directory record Official record
Conditions
Exercise Training, Aging
Interventions
Episodic Future Thinking, Episodic Recent Thinking, Positive Affective Imagery, Neutral Affective Imagery, HIIT Exercise Intervention
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
45 Years to 65 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 19, 2026, 2:02 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Exploring Blood Flow Restriction as an Accessible Fitness Solution for Healthy Aging in Seniors

NCT07460609
View directory record Official record
Conditions
Healthy Ageing
Interventions
Blood Flow Restriction Training Exercise, Health Education
Behavioral
Lead sponsor
Baylor University
Other
Eligibility
60 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Waco, Texas
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Oct 19, 2026, 2:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Bicycling Intervention on Cognitive Skills and Cardiovascular Health

NCT02453178
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
Cycling
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
60 Years to 80 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 30, 2018 · Synced Oct 19, 2026, 2:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Healthy Aging in People With Epilepsy Program

NCT06052605
View directory record Official record
Conditions
Epilepsy
Interventions
Healthy Aging in People with Epilepsy Program, Patient Survey, Provider Survey
Behavioral · Other
Lead sponsor
Anny Reyes
Other
Eligibility
55 Years to 90 Years
Enrollment
380 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 19, 2026, 2:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Dietary Quality and Social Engagement Through a Virtual Nutrition and Teaching Kitchen Intervention Among Older Veterans With Impaired Mobility

NCT06726083
View directory record Official record
Conditions
Impaired Mobility
Interventions
Nutrition Intervention, Contact Control
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
65 Years and older
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 19, 2026, 2:02 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Molecular Optimization Via Exercise (MOVE)

NCT06540287
View directory record Official record
Conditions
Aging
Interventions
Observational
Other
Lead sponsor
Buck Institute for Research on Aging
Other
Eligibility
65 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Novato, California
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Oct 19, 2026, 2:02 AM EDT
Recruiting Not applicable Interventional

Improving Medication Management in World Trade Center Responders

NCT07022990
View directory record Official record
Conditions
Polypharmacy
Interventions
Educational brochure for deprescribing
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
50 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 15, 2025 · Synced Oct 19, 2026, 2:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Using Teleneuropsychology to Optimize Cognition in Healthy Aging: the Web-based Breakfast Game

NCT05506852
View directory record Official record
Conditions
Healthy Aging
Interventions
Web-based training strategy, Web-based regular training (no strategy)
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
60 Years to 75 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 19, 2026, 2:02 AM EDT
Completed Not applicable Interventional

Internet-based Mind-Body Training for Brain Health

NCT07019402
View directory record Official record
Conditions
Subjective Cognitive Decline
Interventions
Internet-based Mindfulness-Based Stress Reduction (iMBSR), Internet-based Lifestyle Education (iLifeEd)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
50 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 19, 2026, 2:02 AM EDT
Completed Not applicable Interventional

Physical Therapists - Recommending EnhanceFitness to Expand Reach

NCT03139461
View directory record Official record
Conditions
Physical Activity, Aging
Interventions
PT-REFER Capacity-building Toolkit
Other
Lead sponsor
University of Washington
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 28, 2020 · Synced Oct 19, 2026, 2:02 AM EDT
Terminated Phase 1 Interventional Results available

Novel Antiaging Regenerative Skin Care Regimen Containing Human Platelet Extract (HPE)

NCT05457491
View directory record Official record
Conditions
Skin Aging
Interventions
Human platelet extract (cosmetic product), Vanicream Gentle Facial Cleanser, EltaMD UV Daily Broad-Spectrum SPF 40, EltaMD PM Therapy Facial Moisturizer, Vanicream Lite Lotion
Biological · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 4, 2024 · Synced Oct 19, 2026, 2:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Enhancing Resilience in Senior Community Residents

NCT05438134
View directory record Official record
Conditions
Quality of Life, Stress, Psychological
Interventions
SMART-3RP Group Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
Not listed
Enrollment
288 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Oct 19, 2026, 2:02 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Geri Pride: Feasibility Pilot of a Group Intervention for Older Veterans

NCT07831759
View directory record Official record
Conditions
Aging, Veterans, Social Determinants of Health, Health Disparate Minority and Vulnerable Populations
Interventions
Geri Pride Health Promotion Group
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2030
U.S. locations
4
States / cities
Tuscaloosa, Alabama • Charleston, South Carolina • Dallas, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 19, 2026, 2:02 AM EDT
Completed Not applicable Interventional

Behavioral Interventions to Prevent or Delay Dementia

NCT02265757
View directory record Official record
Conditions
Mild Cognitive Impairment, Memory Disorders, Mild Dementia, Impaired Cognition, Mild Cognitive Disorder, Amnestic Disorder, Dementia and Amnestic Conditions, Poor Short-term Memory, Memory Impairment
Interventions
Cognitive Rehabilitation, Computer Brain Fitness Training, Support Group (patient and partner), Wellness Education, Physical Exercise
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
50 Years and older
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 22, 2019 · Synced Oct 19, 2026, 2:02 AM EDT