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Showing 1–24 of 52 matching trials from the live ClinicalTrials.gov search.
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Active, not recruiting Phase 3 Interventional

ACHIEVE Brain Health Follow-Up Study

NCT05532657
Conditions
Aging, Cognitive Decline, Mild Cognitive Impairment, Dementia, Hearing Loss
Interventions
Hearing intervention, Successful aging/delayed hearing intervention
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
73 Years and older
Enrollment
629 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
4
States / cities
Hagerstown, Maryland • Minneapolis, Minnesota • Jackson, Mississippi + 1 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Combined Electric and Acoustic Hearing (EAS) in Children and Adults

NCT05923203
Conditions
Cochlear Implant, Hearing Loss
Interventions
Electric and acoustic stimulation (EAS) technology in the implanted ear(s)-this is the combination of a cochlear implant (CI) and hearing aid (HA) in the implanted ear(s)
Other
Lead sponsor
Hearts for Hearing
Other
Eligibility
5 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
4
States / cities
Edmond, Oklahoma • Nashville, Tennessee • Austin, Texas + 1 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Blast Exposed Veterans With Auditory Complaints

NCT02122458
Conditions
Hearing Impairment, Hearing Aid Fitting
Interventions
mild-gain hearing aids with high-frequency emphasis over 6-months
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 50 Years
Enrollment
363 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
3
States / cities
Portland, Oregon • Pittsburgh, Pennsylvania • Sioux Falls, South Dakota
Conditions
Gastroparesis Like Symptoms
Interventions
Activated IB-Stim Device, Inactivated IB-Stim Device
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 60 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Recruiting Not applicable Interventional Accepts healthy volunteers

Use of Airpod Pros as Assistive Technology

NCT06840015
Conditions
Hearing Loss, Adult-Onset, Hearing Aids
Interventions
Airpod Pro as hearing assistive technology
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Richardson, Texas
Completed Not applicable Interventional

Mindfulness Surgical Pain Outcomes

NCT05838443
Conditions
Post Surgical Pain, Surgery
Interventions
Self-directed mindfulness utilizing a multi-sensor EEG-supported device with neurofeedback-assisted and technology-supported meditation, Provider-directed mindfulness, Conventional Care
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
10 Years to 18 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Cincinnati, Ohio
Active, not recruiting Not applicable Interventional

CI Following VS Removal or Labyrinthectomy

NCT03795675
Conditions
Vestibular Schwannoma, Meniere Disease
Interventions
Cochlear Implant
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Not yet recruiting Not applicable Interventional

The Hear Clear Study

NCT07824115
Conditions
Hearing Loss
Interventions
Signal-to-Noise Ratio Enhancement (SNR+), Signal-to-Noise Ratio Neutral (SNR-)
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
2
States / cities
Durham, North Carolina • Columbus, Ohio
Conditions
Unilateral Acoustic Neuroma, Meniere's Disease
Interventions
Cochlear Implant
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Tinnitus
Interventions
Counseling and Sound Therapy
Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
4
States / cities
Iowa City, Iowa • Ann Arbor, Michigan • Buffalo, New York + 1 more
Conditions
Loudness Hyperacusis, Autism Spectrum Disorder (ASD), Hyperacusis
Interventions
Transitional Intervention for Hyperacusis in Autism
Other
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 39 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Orlando, Florida • Dallas, Texas
Completed Not applicable Interventional Results available

Cochlear Implantation in Cases of Single-Sided Deafness

NCT02203305
Conditions
Unilateral Moderate to Profound Hearing Loss, Asymmetric Hearing Loss, Single-Sided Deafness (SSD)
Interventions
Cochlear Implant, Control Group
Device · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Healthy Aging, Health Care Utilization, Health-Related Behavior
Interventions
Annual Wellness Visit, Geriatric Resources and Assessment for the Care of Elders
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
65 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Misophonia
Interventions
Unified Protocols for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents (UP-C/A) for youth with misophonia, Psychoeducation and Relaxation Therapy (PRT)
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
8 Years to 16 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Coral Gables, Florida • St. Petersburg, Florida
Completed Not applicable Interventional Results available

Supplementing Hearing Aids With Computerized Auditory Training

NCT00727337
Conditions
Hearing Loss
Interventions
LACE-computer, PLACEBO-Directed listening, CONTROL, Lace-DVD
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
55 Years to 85 Years
Enrollment
279 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Bay Pines, Florida
Conditions
Tinnitus, Notched Noise Therapy
Interventions
Hearing Aid and Notched Noise Therapy, Hearing Aid and Broadband Noise, Hearing Aid
Combination Product · Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Music
Interventions
Rubato Life App
Device
Lead sponsor
Rubato Life
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Lysosomal Diseases, Gangliosidosis, GM1
Interventions
AAV9-GLB1, Abdominal ultrasound, Rituximab, Sirolimus, Methylprednisolone, Prednisone, Audiology assessment with ABR, Bone density scan (DEXA), Electrocardiogram (EKG), Echocardiogram, Electroencephalogram (EEG) awake and extended overnight, Laboratory tests, Lumbar puncture, Brain MRI/MRS/fMRI, Neurocognitive testing, Neurology exam, PICC or other Central line placement, Skeletal survey, Skin biopsy, Speech and modified barium swallow study, Ophthalmology exam
Biological · Procedure · Drug + 3 more
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
6 Months to 12 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2030
U.S. locations
1
States / cities
Bethesda, Maryland
Completed Not applicable Interventional Results available

Multi-Site Evaluation of Progressive Tinnitus Management

NCT01015781
Conditions
Tinnitus
Interventions
Progressive Tinnitus Management, Wait List Control
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
3
States / cities
West Haven, Connecticut • Portland, Oregon • Memphis, Tennessee
Conditions
Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)
Interventions
DB-OTO
Genetic
Lead sponsor
Regeneron Pharmaceuticals
Industry
Eligibility
Not listed
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2032
U.S. locations
9
States / cities
Los Angeles, California • San Diego, California • Jacksonville, Florida + 6 more
Conditions
Hearing Loss
Interventions
Comparison of PRO-FIT or SELF-FIT fitting
Device
Lead sponsor
Whisper.ai
Industry
Eligibility
18 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
San Francisco, California
Conditions
Presbycusis
Interventions
transcutaneous auricular vagus nerve stimulation, Sham Control
Device
Lead sponsor
University of Florida
Other
Eligibility
55 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Congenital Sensorineural Deafness
Interventions
Telemedicine, In-person ART
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
6 Months to 6 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Aurora, Colorado
Recruiting Not applicable Interventional

Treatment for PTSD and Tinnitus

NCT07106593
Conditions
PTSD - Post Traumatic Stress Disorder, Posttraumatic Stress Disorder (PTSD), Tinnitus
Interventions
Cognitive Processing Therapy, CBT-t
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Antonio, Texas