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ClinicalTrials.gov public records Last synced Oct 2, 2026, 2:32 PM EDT

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Showing 49–72 of 200 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Heart Failure Usual Care Clear all
Completed Phase 2 Interventional Results available

Biomarker Guided Therapies in Stage A/B Heart Failure

NCT02230891
View directory record Official record
Conditions
Hypertension, Diabetes, Cardiovascular Disease
Interventions
Carvedilol, Spironolactone, Usual care
Drug · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 85 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 21, 2022 · Synced Oct 2, 2026, 2:32 PM EDT
Recruiting Phase 3 Interventional

A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

NCT06024746
View directory record Official record
Conditions
Heart Failure
Interventions
Finerenone, Empagliflozin
Drug
Lead sponsor
Colorado Prevention Center
Other
Eligibility
18 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
46
States / cities
Fairhope, Alabama • Phoenix, Arizona • Chula Vista, California + 40 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 2, 2026, 2:32 PM EDT
Completed Phase 1Phase 2 Interventional

Goals of Care Communication

NCT02466100
View directory record Official record
Conditions
Heart Failure
Interventions
goals of care
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 26, 2016 · Synced Oct 2, 2026, 2:32 PM EDT
Not yet recruiting Not applicable Interventional

Palliative Care Intervention to Improve Health Related Quality of Life for Patients on Long-Term LVAD Support

NCT07445932
View directory record Official record
Conditions
Advanced Heart Failure, Mechanical Circulatory Support, Left Ventricular Assist Device, Palliative Care
Interventions
Palliative care intervention
Behavioral
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 2, 2026, 2:32 PM EDT
Completed Not applicable Interventional

Efficacy of an m-Health Cardiac Rehabilitation Program in Heart Failure With Preserved Ejection Fraction

NCT05002075
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
m-health cardiac rehabilitation
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 16, 2024 · Synced Oct 2, 2026, 2:32 PM EDT
Not yet recruiting Not applicable Interventional

Health Coaching for Patients With Cardiovascular Disease

NCT06904144
View directory record Official record
Conditions
Congestive Heart Failure Treated, Myocardial Infarction (MI), Coronary Artery Disease, Congestive Heart Failure Chronic
Interventions
Health Coaching
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 2, 2026, 2:32 PM EDT
Terminated Not applicable Interventional

Automated MEdical Record Driven Implantable CArdioverter-defibrillator Heart Failure Trial (AMERICA-HF)

NCT01807130
View directory record Official record
Conditions
Heart Failure
Interventions
Automated HF/EP Referral, Placebo (Registry Arm)
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 10, 2014 · Synced Oct 2, 2026, 2:32 PM EDT
Recruiting Not applicable Interventional

Remote Dielectric Sensing (ReDS) Assisted Diuresis in Acute Decompensated Heart Failure

NCT03586336
View directory record Official record
Conditions
Heart Failure; With Decompensation
Interventions
ReDS-Guided, Usual Care
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 2, 2026, 2:32 PM EDT
Completed Not applicable Interventional

Education and Supportive Partners Improving Self-Care (ENSPIRE)

NCT00166049
View directory record Official record
Conditions
Heart Failure
Interventions
Family Partnership Intervention (FPI), Patient and Family Education, Usual care with educational material
Behavioral
Lead sponsor
Emory University
Other
Eligibility
21 Years to 79 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
4
States / cities
Atlanta, Georgia • Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 11, 2015 · Synced Oct 2, 2026, 2:32 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving TRansitions ANd OutcomeS for Heart FailurE Patients in Home Health CaRe (I-TRANSFER-HF)

NCT06118983
View directory record Official record
Conditions
Heart Failure
Interventions
I-TRANSFER-HF
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
1,094 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 2, 2026, 2:32 PM EDT
Not listed Phase 1Phase 2 Interventional

Management of Volume Overload HF Patients by Individual DSR Treatment adJustment-a clinicAl inVestigation of InfusatE2.0

NCT05965934
View directory record Official record
Conditions
Heart Failure, Volume Overload
Interventions
Direct Sodium Removal Infusate 2.0
Drug
Lead sponsor
Sequana Medical N.V.
Industry
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 28, 2023 · Synced Oct 2, 2026, 2:32 PM EDT
Completed Not applicable Interventional Results available

Promoting Patient-Centered Care Through a Heart Failure Simulation Study

NCT01917188
View directory record Official record
Conditions
Heart Failure
Interventions
Full simulation and education, See simulation room, usual education
Behavioral
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Jan 16, 2019 · Synced Oct 2, 2026, 2:32 PM EDT
Completed Not applicable Interventional

Interventions to Improve Daily Activity in Heart Failure

NCT02331524
View directory record Official record
Conditions
Heart Failure
Interventions
Activity Feedback and Encouragement, Health Coaching/Home Exercise
Behavioral · Other
Lead sponsor
Grand Valley State University
Other
Eligibility
40 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Oct 2, 2026, 2:32 PM EDT
Completed Not applicable Interventional

A Pilot Trial of Patient Decision Aids for Implantable Cardioverter-Defibrillators (ICDs)

NCT02026102
View directory record Official record
Conditions
Systolic Heart Failure, Sudden Cardiac Death
Interventions
ICD Decision Aid Toolkit
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
3
States / cities
Aurora, Colorado • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 31, 2019 · Synced Oct 2, 2026, 2:32 PM EDT
Terminated Phase 2 Interventional Results available

Subcutaneous Furosemide in Acute Decompensated Heart Failure: The SUBQ-HF Study

NCT03170219
View directory record Official record
Conditions
Acute Heart Failure, Decompensated Heart Failure
Interventions
subcutaneous furosemide and sc2wear device
Combination Product
Lead sponsor
Adrian Hernandez
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
16
States / cities
Atlanta, Georgia • Chicago, Illinois • Baltimore, Maryland + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 23, 2019 · Synced Oct 2, 2026, 2:32 PM EDT
Not listed Not applicable Interventional

Intensive Education Versus Usual Education of Patients for Improving Guideline Directed Medical Therapy (GDMT) Prescription in Heart Failure With Reduced Ejection Fraction

NCT06273085
View directory record Official record
Conditions
Heart Failure, Patient Acceptance of Health Care
Interventions
Patient education
Behavioral
Lead sponsor
Medstar Health Baltimore
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
4
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 26, 2024 · Synced Oct 2, 2026, 2:32 PM EDT
Recruiting Not applicable Interventional

Tier - Palliative Care For Patients With Advanced Heart Failure or Cancer

NCT06228209
View directory record Official record
Conditions
Advanced Heart Failure, Advanced Non-Colorectal Gastointestinal Cancer, Advanced Lung Cancer
Interventions
Tier-Palliative Care
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 2, 2026, 2:32 PM EDT
Withdrawn Not applicable Interventional

e-Diary in Heart Failure

NCT03452683
View directory record Official record
Conditions
Heart Failure
Interventions
Movn Mobile App
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Concord, California
Source: ClinicalTrials.gov public record
Updated Jun 26, 2018 · Synced Oct 2, 2026, 2:32 PM EDT
Recruiting Not applicable Interventional

NT-ProBNP-based Heart Failure Screening and Prevention Trial in Patients With Type 2 Diabetes: STRONG-DM Study

NCT06593327
View directory record Official record
Conditions
Type 2 Diabetes, Diabetic Cardiomyopathy, Heart Failure, Cardiometabolic Diseases
Interventions
Intensive Prevention Strategy
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
3
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 2, 2026, 2:32 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Impact of Early Diagnosis and Treatment of OSA on Hospital Readmission in Hospitalized Cardiac Patients

NCT03647891
View directory record Official record
Conditions
OSA, Heart Failure, Myocardial Infarction, Arrhythmia, Cardiac
Interventions
Continuous Positive Airway Pressure
Device
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Fontana, California
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 2, 2026, 2:32 PM EDT
Completed Not applicable Interventional

Risk EValuation And Its Impact on ClinicAL Decision Making and Outcomes in Heart Failure

NCT03845660
View directory record Official record
Conditions
Heart Failure
Interventions
Electronic Alert
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
3,124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 22, 2022 · Synced Oct 2, 2026, 2:32 PM EDT
Completed Not applicable Interventional

Get With the Guidelines in ED Patients With Heart Failure

NCT02519283
View directory record Official record
Conditions
Heart Failure
Interventions
GUIDED-HF, Standard of Care
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
21 Years and older
Enrollment
529 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
15
States / cities
Atlanta, Georgia • Indianapolis, Indiana • Iowa City, Iowa + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2020 · Synced Oct 2, 2026, 2:32 PM EDT
Completed Not applicable Interventional

A Trial to Reduce Readmissions Using Motivational Interviewing and Interactive Voice Response

NCT01855022
View directory record Official record
Conditions
Congestive Heart Failure (CHF), Chronic Obstructive Pulmonary Disease (COPD)
Interventions
MI + IVR
Behavioral
Lead sponsor
Asante Health System
Other
Eligibility
18 Years and older
Enrollment
512 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
2
States / cities
Grants Pass, Oregon • Medford, Oregon
Source: ClinicalTrials.gov public record
Updated May 16, 2013 · Synced Oct 2, 2026, 2:32 PM EDT
Withdrawn Phase 4 Interventional

Comparison of ARNI to Alternate Oral Vasodilator Therapies in Patients With Low Cardiac Output

NCT04206865
View directory record Official record
Conditions
Cardiogenic Shock
Interventions
Sacubitril-Valsartan, Standard Oral Vasodilators
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Oct 2, 2026, 2:32 PM EDT