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ClinicalTrials.gov public records Last synced Oct 26, 2026, 10:52 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1177–1200 of 1,714 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Heart-Rate Clear all
Recruiting No phase listed Observational

Delirium Identification in Older Patients With Alzheimer's and Other Related Dementias In the Emergency Department

NCT06326424
View directory record Official record
Conditions
Delirium, Dementia, Hospital Acquired Condition
Interventions
Empatica EmbracePlus
Device
Lead sponsor
Ohio State University
Other
Eligibility
65 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Oct 26, 2026, 10:52 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Medibio DDA Confirmatory Performance Study

NCT03529513
View directory record Official record
Conditions
Major Depressive Episode
Interventions
Medibio Depression Diagnostic Aid, Mini International Neuropsychiatric Interview, Hamilton Rating Scale for Depression - 17 Item
Diagnostic Test
Lead sponsor
Medibio Limited
Industry
Eligibility
18 Years to 75 Years
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
6
States / cities
Garden Grove, California • Torrance, California • Mason, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 21, 2023 · Synced Oct 26, 2026, 10:52 PM EDT
Completed Phase 3 Interventional

Safety and Efficacy of Nebivolol in the Treatment of Hypertension in African Americans

NCT00145210
View directory record Official record
Conditions
Hypertension
Interventions
Nebivolol and Atenolol
Drug
Lead sponsor
Mylan Bertek Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
630 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Mar 7, 2008 · Synced Oct 26, 2026, 10:52 PM EDT
Terminated Not applicable Interventional

Radiofrequency (RF) Ablation for Atrial Fibrillation (AF) in Patients With Heart Failure With Preserved Ejection Fraction

NCT04327596
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
RF ablation of AF using CARTO 3 and a Thermocool ST SF ablation catheter
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
50 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
2
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 23, 2022 · Synced Oct 26, 2026, 10:52 PM EDT
Terminated Phase 3 Interventional Results available

Safety Study of Intranasal Etripamil for the Termination of Spontaneous Episodes of Paroxysmal Supraventricular Tachycardia (PSVT). NODE-302

NCT03635996
View directory record Official record
Conditions
Paroxysmal Supraventricular Tachycardia
Interventions
Etripamil NS 70 mg, Aptar Pharma Nasal Spray Bidose System
Drug · Device
Lead sponsor
Milestone Pharmaceuticals Inc.
Other
Eligibility
18 Years and older
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
22
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Los Alamitos, California + 18 more
Source: ClinicalTrials.gov public record
Updated Nov 5, 2024 · Synced Oct 26, 2026, 10:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Prehabilitative Exercise on Functional Recovery Following Total Knee Arthroplasty

NCT03227120
View directory record Official record
Conditions
Arthroplasty, Osteoarthritis, Knee
Interventions
Prehabilitation exercise
Other
Lead sponsor
Carilion Clinic
Other
Eligibility
50 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 7, 2020 · Synced Oct 26, 2026, 10:52 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Study to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured From the Onset of the QRS Complex to the End of the T Wave Corrected for Heart Rate)

NCT01511029
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis
Interventions
Dexpramipexole, Dexpramipexole Placebo, Moxifloxacin
Drug
Lead sponsor
Knopp Biosciences
Industry
Eligibility
18 Years to 60 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Nov 25, 2014 · Synced Oct 26, 2026, 10:52 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

World Trade Center Adolescent Health Study

NCT02068183
View directory record Official record
Conditions
Asthma, Hypertension, Cardiovascular Risk Factor, Insulin Resistance, Stress Disorders, Post-Traumatic, Exposure to Toxic Dust
Interventions
Not listed
Lead sponsor
NYU Langone Health
Other
Eligibility
12 Years to 20 Years
Enrollment
402 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 24, 2017 · Synced Oct 26, 2026, 10:52 PM EDT
Completed Not applicable Interventional

Exercise for People with Spinal Cord Injury

NCT04007445
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Formally Directed Group (Exercise Group), Self-Directed Group (Control Group)
Behavioral · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 28, 2025 · Synced Oct 26, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional

Mindfulness and Wearable Biosensors to Prevent Hypertensive Disorders of Pregnancy

NCT07218237
View directory record Official record
Conditions
Preeclampsia
Interventions
Mindfulness training, Garmin Vivoactive 4 watch
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Providence, Rhode Island • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 26, 2026, 10:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exercise as a Buffer Against Stress-induced Overeating

NCT02936076
View directory record Official record
Conditions
Obesity
Interventions
Exercise intervention, Delayed exercise intervention
Other
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 29, 2021 · Synced Oct 26, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional

Heart Coherence Training on Vascular Ehlers-Danlos Syndrome Patients

NCT05994664
View directory record Official record
Conditions
Vascular Ehlers-Danlos Syndrome
Interventions
Heartmath Intervention, Control Group
Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
12 Years to 45 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 1, 2024 · Synced Oct 26, 2026, 10:52 PM EDT
Withdrawn Phase 4 Interventional

Effects of Canagliflozin on Intravascular Volume and Hemodynamics

NCT03190798
View directory record Official record
Conditions
Type2 Diabetes Mellitus, Cardiovascular Diseases
Interventions
Canagliflozin 300mg, Placebo
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Oct 26, 2026, 10:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Exercise on the Disease Activity of Rheumatoid Arthritis

NCT00792675
View directory record Official record
Conditions
Rheumatoid Arthritis
Interventions
Aerobic and resistance exercise training
Other
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 65 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2006
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 30, 2023 · Synced Oct 26, 2026, 10:52 PM EDT
Active, not recruiting Not applicable Interventional

Breathing Device in Postural Orthostatic Tachycardia Syndrome (POTS)

NCT00962728
View directory record Official record
Conditions
Postural Tachycardia Syndrome, Postural Orthostatic Tachycardia Syndrome
Interventions
Inspiratory Threshold Device (Res-Q-Gard ITD), Sham Inspiratory Threshold Device
Device
Lead sponsor
Alfredo Gamboa
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 26, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Exercise and Protein Efficiency in T2D

NCT07477067
View directory record Official record
Conditions
Type 2 Diabetes, Control Condition
Interventions
12 week progressive exercise training
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
65 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 26, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

How a Single Workout Affects Gut Bugs in Women With Different Fitness Levels and Body Types

NCT06691100
View directory record Official record
Conditions
Weight Management, Obesity, Exercise, Women, Gut Microbiome, Metabolome, Health, Gut Microbiota
Interventions
Aerobic Exercise
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
21 Years to 40 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 26, 2026, 10:52 PM EDT
Completed Not applicable Interventional

A Study of a Technology-enabled Disease Management Program to Reduce Hospitalizations for Heart Failure

NCT02084992
View directory record Official record
Conditions
Congestive Heart Failure, Diastolic Heart Failure, Systolic Heart Failure
Interventions
Expanded technology disease management, Telephonic disease management
Other
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
2
States / cities
Boston, Massachusetts • Framingham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 17, 2019 · Synced Oct 26, 2026, 10:52 PM EDT
Completed Not applicable Interventional

Pilot Study of Physiological Effect of High-Flow Nasal Cannula on Respiratory Pattern and Work of Breathing

NCT02514798
View directory record Official record
Conditions
COPD
Interventions
Esophageal and gastric balloons, Respiratory Inductance Plethysmography (RIP) system, Sentec transcutaneous monitoring system, High-flow humidified nasal oxygen delivery system, CPAP (Positive Control)
Other · Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 10, 2022 · Synced Oct 26, 2026, 10:52 PM EDT
Not yet recruiting No phase listed Observational

Validation and Feasibility of Noninvasive Oxygen Delivery Index Monitoring in Cardiac Surgery Patients

NCT07573306
View directory record Official record
Conditions
Cardiac Surgery
Interventions
SpHb monitor
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 26, 2026, 10:52 PM EDT
Terminated Phase 1 Interventional

Next Generation Personalized Neuroblastoma Therapy

NCT02780128
View directory record Official record
Conditions
Neuroblastoma, Cancer
Interventions
Biopsy, Next Generation Sequencing, Tumor Scans, Bone marrow Tests, Physical Exam, Eye Exam, Labs, Pregnancy Test, Interviews, ECG, Echocardiogram, Ribociclib, Ceritinib
Procedure · Genetic · Other + 2 more
Lead sponsor
Yael P Mosse
Other
Eligibility
1 Year to 21 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Oct 26, 2026, 10:52 PM EDT
Terminated Not applicable Interventional Results available

Hemodynamic Instability Index: The Impact to Care With a New Predictive Indicator

NCT02185521
View directory record Official record
Conditions
Shock, Hemodynamic Instability
Interventions
patient assessment
Other
Lead sponsor
Philips Healthcare
Industry
Eligibility
18 Years and older
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
2
States / cities
St Louis, Missouri • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 11, 2019 · Synced Oct 26, 2026, 10:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ketone Ester Supplementation and Nocturnal Blood Pressure

NCT05888506
View directory record Official record
Conditions
Cardiovascular Diseases in Old Age, Aging, Cardiovascular Diseases, Sleep
Interventions
Ketone Ester, Placebo
Dietary Supplement
Lead sponsor
Georgia Southern University
Other
Eligibility
50 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Savannah, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 6, 2023 · Synced Oct 26, 2026, 10:52 PM EDT
Completed No phase listed Observational

Substantial Equivalence Study for Kai Sensors RSpot Non-Contact Respiratory Rate Spot Check

NCT00827905
View directory record Official record
Conditions
Respiration
Interventions
RSpot Non-Contact Respiratory Rate Spot Check
Device
Lead sponsor
Kai Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Aug 6, 2010 · Synced Oct 26, 2026, 10:52 PM EDT