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ClinicalTrials.gov public records Last synced Sep 27, 2026, 5:48 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Heat Therapy Group Clear all
Completed Not applicable Interventional Results available

Collaborative Care for Older Adults With Back Pain (COCOA)

NCT01312233
View directory record Official record
Conditions
Low Back Pain
Interventions
Medical Care, Dual Care, Shared Care
Other
Lead sponsor
Palmer College of Chiropractic
Other
Eligibility
65 Years and older
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Davenport, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 29, 2021 · Synced Sep 27, 2026, 5:48 PM EDT
Completed Not applicable Interventional Results available

A New Method for Identifying Sensory Changes in Painful Chemotherapy-induced Peripheral Neuropathy (CIPN)

NCT03687970
View directory record Official record
Conditions
Chemotherapy-induced Peripheral Neuropathy
Interventions
Brief Pain Inventory, Hospital Anxiety and Depression Scale, Neuropathic Pain Symptom Inventory, Diode Laser fiber type Selective Stimulator, Quantitative sensory testing, Conditioned pain modulation efficiency, Spontaneous pain at baseline on 0-10 Numerical Rating Scale (NRS)
Other · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 18, 2021 · Synced Sep 27, 2026, 5:48 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

LT Vaccine Patch Self-Administration Study

NCT00565461
View directory record Official record
Conditions
Prevention of Travelers' Diarrhea
Interventions
heat-labile enterotoxin of E. coli (LT)
Biological
Lead sponsor
Intercell USA, Inc.
Industry
Eligibility
18 Years to 64 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
3
States / cities
Little Rock, Arkansas • South Miami, Florida • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 29, 2020 · Synced Sep 27, 2026, 5:48 PM EDT
Completed Not applicable Interventional Results available

to Evaluate the Effectiveness and Safety of the Tixel® , VS LipiFlow® in the Treatment of Meibomian Gland Dysfunction

NCT05162261
View directory record Official record
Conditions
Meibomian Gland Dysfunction, Dry Eye Syndromes, Dry Eye
Interventions
Tixel C, LipiFlow
Device
Lead sponsor
Novoxel Ltd.
Industry
Eligibility
22 Years and older
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
5
States / cities
La Jolla, California • Newport Beach, California • Kansas City, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 21, 2025 · Synced Sep 27, 2026, 5:48 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Heat Therapy, Functional Capacity, and Vascular Health in Older Adults

NCT05706181
View directory record Official record
Conditions
Aging Well, Walking, Difficulty, Hyperemia
Interventions
Home-based leg heat therapy, Home-based sham therapy
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
55 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Sep 27, 2026, 5:48 PM EDT
Completed Early Phase 1 Interventional

Photobiomodulation for the Treatment of Diabetic Macular Edema

NCT02457975
View directory record Official record
Conditions
Diabetic Retinopathy
Interventions
670nm PBM, intravitreous VEGF-inhibitors
Device · Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Sep 27, 2026, 5:48 PM EDT
Completed Not applicable Interventional Results available

Treatment of Meibomian Gland Dysfunction Prior to Cataract Surgery

NCT01808560
View directory record Official record
Conditions
Blepharitis, Dry Eye Syndrome
Interventions
LipiFlow Pre-Treatment, LipiFlow Post-treatment
Device
Lead sponsor
TearScience, Inc.
Industry
Eligibility
55 Years to 85 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
7
States / cities
Hoffman Estates, Illinois • Lake Villa, Illinois • Winchester, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2018 · Synced Sep 27, 2026, 5:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Subacute Low Back Pain in Active Duty

NCT03502187
View directory record Official record
Conditions
Subacute Low Back Pain
Interventions
Progressive Exercise Plan, NeuromuscularElectricalStimulation(NMES), Primary Care Management (PCM)
Behavioral · Device
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years to 45 Years
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Fort Campbell North, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 24, 2022 · Synced Sep 27, 2026, 5:48 PM EDT
Not listed No phase listed Observational

Pulsed Heat as a Drug-free Treatment for Pregnancy Related Pain

NCT05628298
View directory record Official record
Conditions
Pain, Pain, Labor
Interventions
Soovu Pain Relief System
Device
Lead sponsor
Soovu Labs Inc.
Industry
Eligibility
18 Years to 60 Years · Female only
Enrollment
35 participants
Timeline
2023 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 27, 2022 · Synced Sep 27, 2026, 5:48 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Transdermal Patch CVD 1000: The Effect of Heat on Nicotine Release From Nicotine Patches in Adult Smokers

NCT02371850
View directory record Official record
Conditions
Smoking
Interventions
Nicoderm patch first, then Aveva patch
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 45 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 15, 2021 · Synced Sep 27, 2026, 5:48 PM EDT
Recruiting Not applicable Interventional

Repeated Far Infrared Sauna Bathing in Adults With Obesity

NCT07158047
View directory record Official record
Conditions
Obesity (Disorder)
Interventions
Heat therapy
Other
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 59 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Sep 27, 2026, 5:48 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Cognitive Enhancement Through Transcranial Laser Therapy

NCT02851173
View directory record Official record
Conditions
Healthy Participants, Mild Cognitive Impairment
Interventions
LLLT, Placebo
Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
45 Years and older
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 3, 2023 · Synced Sep 27, 2026, 5:48 PM EDT
Completed Not applicable Interventional

Evaluation of Pain Neuroscience Education for Patients Who Experience Chronic Pain With Concurrent Opioid Dependence

NCT06442306
View directory record Official record
Conditions
Chronic Pain, Opioid Dependence
Interventions
Pain Neuroscience Education, General Health Education
Other
Lead sponsor
Wichita State University
Other
Eligibility
18 Years to 95 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 3, 2024 · Synced Sep 27, 2026, 5:48 PM EDT
Completed Not applicable Interventional Results available

Conservative Treatment of Patients With Temporomandibular Disorders

NCT01021306
View directory record Official record
Conditions
Temporomandibular Disorders
Interventions
Chiropractic w/Activator & Self Care, Dental Care & Self Care, Sham AMCT, Self-Care Only Group
Device · Other
Lead sponsor
Palmer College of Chiropractic
Other
Eligibility
21 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
3
States / cities
Coralville, Iowa • Davenport, Iowa • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 21, 2017 · Synced Sep 27, 2026, 5:48 PM EDT
Active, not recruiting Phase 2 Interventional Results available

Protocol for the Study and Treatment of Participants With Intraocular Retinoblastoma

NCT01783535
View directory record Official record
Conditions
Retinoblastoma
Interventions
vincristine, topotecan, filgrastim, PEG-filgrastim, carboplatin, focal therapy, etoposide, cyclophosphamide, MESNA, doxorubicin, enucleation, external beam radiation or proton beam radiation
Drug · Other · Procedure + 1 more
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
Not listed
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2027
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 27, 2026, 5:48 PM EDT
Completed Not applicable Interventional

Emergency Department Digital Pain Self-Management Intervention to Improve Acute Low Back Pain Outcomes

NCT06360341
View directory record Official record
Conditions
Low Back Pain, Mechanical, Acute Pain
Interventions
Emergency Department Digital Pain Self-Management Intervention (EDPSI), Routine Discharge Care
Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 26, 2025 · Synced Sep 27, 2026, 5:48 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cold and Heat Investigation to Lower Levels of Depression

NCT06263738
View directory record Official record
Conditions
Depression, Mood Disorders, Healthy (Controls)
Interventions
Whole Body Hyperthermia, Cold Water Plunge
Procedure
Lead sponsor
Barry Sandler
Other
Eligibility
18 Years to 65 Years
Enrollment
162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Edwards, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Sep 27, 2026, 5:48 PM EDT
Recruiting Not applicable Interventional

Pro-2-Cool Pivotal Trial II

NCT06929923
View directory record Official record
Conditions
Concussion, Mild
Interventions
Pro2Cool Device, Sham Cooling Garment Device
Device
Lead sponsor
TecTraum Inc.
Industry
Eligibility
13 Years to 21 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
3
States / cities
Ann Arbor, Michigan • Akron, Ohio • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 27, 2026, 5:48 PM EDT
Not listed Not applicable Interventional

Effectiveness of Laser Hair Removal in Pilonidal Disease

NCT03276065
View directory record Official record
Conditions
Pilonidal Disease
Interventions
Laser depilation, Standard of care hair depilation
Device · Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
11 Years to 21 Years
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 24, 2022 · Synced Sep 27, 2026, 5:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Relationship Between Chiropractic Care and Autonomic Nervous System Regulation

NCT05401903
View directory record Official record
Conditions
Chiropractic Maintenance Care and Heart Rate Variability
Interventions
Chiropractic Maintenance Care
Other
Lead sponsor
Northeast College of Health Sciences
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Seneca Falls, New York
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Sep 27, 2026, 5:48 PM EDT
Recruiting Not applicable Interventional

The Effect of Manual Physical Therapy and Exercise in Addition to Routine Dental Care in Individuals With Temporomandibular Disorders

NCT06602375
View directory record Official record
Conditions
Temporomandibular Disorders (TMD)
Interventions
Standard care, Physical Therapy (PT)
Other
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 55 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 4, 2025 · Synced Sep 27, 2026, 5:48 PM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation in Older Persons With Knee Pain (Knee Pain and tDCS): Randomized Pilot Study

NCT02512393
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
45 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 10, 2017 · Synced Sep 27, 2026, 5:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Novel Multimodal Pain Control Protocol for Minimally Invasive Gynecologic Surgery

NCT04710277
View directory record Official record
Conditions
Postoperative Pain, Narcotic Use, Cryotherapy Effect
Interventions
Opioid-sparing multimodal pain management, Usual care
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older · Female only
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 11, 2023 · Synced Sep 27, 2026, 5:48 PM EDT
Completed Not applicable Interventional Results available

Esophageal Cooling for AF Ablation

NCT03691571
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Esophageal Cooling, Control
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 4, 2022 · Synced Sep 27, 2026, 5:48 PM EDT