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ClinicalTrials.gov public records Last synced Sep 4, 2026, 7:11 AM EDT

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Showing 1–24 of 56 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Chronic Urticaria (CU): Chronic Inducible Urticaria (CINDU) and Chronic Spontaneous Urticaria (CSU)
Interventions
Remibrutinib, Placebo
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
North Miami Beach, Florida • Glenview, Illinois
Completed Not applicable Interventional Accepts healthy volunteers Results available

Skin Surface and Intradermal Temperature Responses to Heat Stress

NCT06593067
Conditions
Hyperthermia
Interventions
Control, Fan, Fan and Water Spray, Water Spray
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Long COVID Fatigue
Interventions
Ketogenic Metabolic Therapy, Lifestyle Intervention
Other · Behavioral
Lead sponsor
National University of Natural Medicine
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Withdrawn Not applicable Interventional Accepts healthy volunteers

NOICE vs. Nothing | Thermode

NCT06919497
Conditions
Spatial Audio Stimulation
Interventions
Spatial audio stimulation, No spatial audio stimulation
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cardiovascular Responses to Heat Waves in the Elderly

NCT04538144
Conditions
Aging, Hyperthermia
Interventions
Hot and Humid Trial, Hot and Dry Trial
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Completed No phase listed Observational Accepts healthy volunteers

Exertional Heat Illness: Biomarkers for Prediction and Return to Duty

NCT01434979
Conditions
Heat Illness
Interventions
Not listed
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 45 Years
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Terminated Not applicable Interventional

Heat Waves and the Elderly With COPD

NCT06295523
Conditions
COPD, Aging, Hyperthermia
Interventions
Water Spray, Control
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
65 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Work-related Injury
Interventions
Motivational Interview (MI), Participatory Group Activity, Control Condition
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
21 Years and older · Male only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Houston, Texas
Completed Phase 4 Interventional Accepts healthy volunteers Results available

The Influence of Menthol Gel During Exercise With Heat

NCT05302804
Conditions
Acute Exercise, Heat Exposure
Interventions
Menthol Gel, Control Gel
Drug
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 45 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Omaha, Nebraska
Completed Not applicable Interventional Accepts healthy volunteers

Offset Analgesia as a Measure of Central Sensitization in Children

NCT03445403
Conditions
Chronic Pain Syndrome, Chronic Daily Headache, Functional Abdominal Pain Syndrome, Musculoskeletal Pain Disorder, CRPS (Complex Regional Pain Syndromes)
Interventions
Offset analgesia
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
10 Years to 17 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Waltham, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Continuous Airway Pressure on the Ability to Heat and Humidify Air

NCT00338403
Conditions
Healthy
Interventions
Continuous positive airway pressure (CPAP) at -5, 0, 5 and 10 cm of water
Procedure
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 55 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Novel Cooling Vest to Protect Persons With SCI From Hyperthermia

NCT05441449
Conditions
Spinal Cord Injuries
Interventions
Cooling Vest
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 68 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
The Bronx, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exercise in Burn Survivors: Cooling Modalities

NCT04512976
Conditions
Burn Injury
Interventions
Control (no cooling modalities), Water Spray Only, Fan Only, Water Spray and Fan
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Pain in Fibrous Dysplasia

NCT04125862
Conditions
Fibrous Dysplasia/McCune-Albright Syndrome
Interventions
MRI-based Neuroimaging, Non-contrast MRI, 18F-FDG-PET/CT, 18F-NaF-PET/CT
Diagnostic Test
Lead sponsor
Boston Children's Hospital
Other
Eligibility
10 Years to 45 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Work-related Injury
Interventions
individual -Brief Motivational Intervention (BMI), Group (Group Problem Solving), Standard of Care (OSHA 10 Safety Cards)
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
325 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Houston, Texas
Conditions
Contraception, Iron Deficiencies
Interventions
Blood volume and environmental testing
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 40 Years · Female only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Natick, Massachusetts
Recruiting No phase listed Observational

The APS Phenotyping Study

NCT06521502
Conditions
ARDS, Sepsis, Pneumonia
Interventions
Blood collection, Urine Collection, Nasal, oral, and rectal swabs, Stool collection, Heat Moisture Exchange Filter collection, Tracheal Aspirate sample collection, Non-bronchoscopic bronchoalveolar lavage (NBBAL), Surveys, Short physical performance battery, Hand grip strength, CNS Vital Signs, Muscle Ultrasound, Muscle Strength, Spirometry, Lung Diffusion Testing (DLCO), Chest CT Scan
Other · Procedure · Radiation
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
20
States / cities
Fresno, California • Palo Alto, California • San Francisco, California + 12 more
Conditions
Bladder Outlet Obstruction, BPH
Interventions
High Intensity Focused Ultrasound
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
45 Years to 80 Years · Male only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Pain Effect on Attention Using an Ipad Game App

NCT03115788
Conditions
Cognitive Function
Interventions
Heat induced pain, Cold Induced Pain, iPad
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 55 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2025
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Obesity, Polycystic Ovary Syndrome, Prehypertension, PreDiabetes, Cardiovascular Risk Factor, Metabolic Syndrome
Interventions
Heat therapy
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Eugene, Oregon
Completed Not applicable Interventional Accepts healthy volunteers

The Brain on Whole Body Hyperthermia: A Neuroimaging Study

NCT02062840
Conditions
Major Depression
Interventions
High intensity whole-body infrared heating, Low intensity whole-body infrared heating, Functional Magnetic Resonance Imaging (fMRI) and electrocardiogram (EKG), Questionnaires
Device · Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 30 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Tucson, Arizona
Conditions
Chemotherapy-induced Peripheral Neuropathy
Interventions
photobiomodulation, Sham treatment, Physiotherapy
Device · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Minneapolis, Minnesota
Completed Not applicable Interventional Accepts healthy volunteers

Whole Body Hyperthermia and Major Depression (MDD)

NCT01625546
Conditions
Depressive Disorder, Major
Interventions
Whole Body Hyperthermia system
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Tucson, Arizona
Completed Not applicable Interventional Accepts healthy volunteers

IR and Microvascular Blood Flow in SCI

NCT02034331
Conditions
Spinal Cord Injury, Insulin Resistance
Interventions
Insulin iontophoresis, Placebo Iontophoresis, Acetylcholine Iontophoresis, Heat application
Drug · Other
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
20 Years to 69 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
The Bronx, New York