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ClinicalTrials.gov public records Last synced Sep 3, 2026, 2:30 AM EDT

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Showing 1–24 of 27 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Osteoarthritis, Knee Pain
Interventions
"Kineticure System" followed by sham, sham followed by "Kineticure System"
Device
Lead sponsor
Kineticure
Industry
Eligibility
45 Years to 80 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Jacksonville, Florida
Conditions
Peripheral Artery Disease
Interventions
Leg heat therapy, Sham Control
Device
Lead sponsor
Indiana University
Other
Eligibility
50 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Low Back Pain, Pregnancy
Interventions
Soft Tissue Mobilization, Soft Tissue Massage
Procedure
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Lubbock, Texas
Conditions
Hypertension
Interventions
Clonidine, Nitroglycerin transdermal, Dipyridamole/ Aspirin (Aggrenox), Desmopressin (DDAVP), Sildenafil, Nifedipine, Hydralazine, Hydrochlorothiazide, Placebo, Bosentan, Diltiazem, Eplerenone, guanfacine, L-arginine, captopril, carbidopa, losartan, metoprolol tartrate, nebivolol hydrochloride, prazosin hydrochloride, tamsulosin hydrochloride, Head-up tilt., aliskiren, Local heat stress
Drug · Dietary Supplement · Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 80 Years
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Completed Not applicable Interventional Accepts healthy volunteers

BACK4 Safety Evaluation

NCT07153900
Conditions
Safety and Tolerability in Healthy Subjects
Interventions
Treatment with BACK4 System
Device
Lead sponsor
SWIMS America Corp.
Industry
Eligibility
22 Years to 55 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Birmingham, Michigan
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Whole-Body Hyperthermia for Mood and Anxiety Disorders

NCT06144294
Conditions
Postpartum Depression, Mood Disorders, Anxiety Disorders, Postpartum Anxiety
Interventions
Whole-Body Hyperthermia, fMRI
Other · Diagnostic Test
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 50 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2028 – 2032
U.S. locations
1
States / cities
New York, New York
Conditions
Hypertension, Pure Autonomic Failure, Multiple System Atrophy, Autonomic Failure
Interventions
Heating pad, Sham control
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Restless Legs Syndrome
Interventions
MMF07 Foot Massager, Heat Therapy
Device
Lead sponsor
Ariane Park
Other
Eligibility
18 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Diabetes Mellitus, Insulin-Dependent
Interventions
InsuPatch
Device
Lead sponsor
Insuline Medical Ltd.
Industry
Eligibility
18 Years to 65 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
San Mateo, California
Withdrawn Not applicable Interventional Accepts healthy volunteers

Heating Pad for in Office Cystoscopy and Urodynamic Testing

NCT05981794
Conditions
Anxiety, Pain, Distress, Emotional
Interventions
Electrical heating pad, Sham heating pad
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Type 2 Diabetes
Interventions
Heat therapy, Sham
Device
Lead sponsor
Purdue University
Other
Eligibility
55 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
West Lafayette, Indiana
Conditions
Peripheral Arterial Disease
Interventions
Lower leg heating, Lower leg transcutaneous electrical nerve stimulation (TENS)
Behavioral
Lead sponsor
Salisbury University
Other
Eligibility
40 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Salisbury, Maryland
Conditions
Molecular Imaging
Interventions
Meal, Exercise, Sestamibi, Caffeine Tablet, External Heating
Dietary Supplement · Other · Radiation + 1 more
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years to 70 Years · Female only
Enrollment
154 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Completed Not applicable Interventional Accepts healthy volunteers Results available

Intraoperative Warming Comparison of Devices

NCT00650260
Conditions
Hypothermia
Interventions
Dynatherm Medical vitalHEAT Temperature Management System vH2, Bair Hugger™ (Arizant Healthcare, Eden Prairie, MN)
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Hypertension, Pure Autonomic Failure, Multiple System Atrophy, Autonomic Failure
Interventions
Passive heat stress, Control (non-heating)
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
PAD
Interventions
Without Heating, Warm Bath, Neutral Bath, Heating Suit, Lower limb warm water immersion, Gardner walking protocol
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
21 Years to 85 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Hershey, Pennsylvania
Conditions
Pressure Ulcer, Pressure Injury
Interventions
Dabir Micropressure Overlay
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
6,627 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Recruiting No phase listed Observational Accepts healthy volunteers

The Cardiovascular Impact of Hot Flushes

NCT05251324
Conditions
Hot Flashes, Menopause
Interventions
Hot Flush Induction
Other
Lead sponsor
University of Minnesota
Other
Eligibility
40 Years to 70 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Topical Heat Application for Intraoperative Abortion Pain Management
Interventions
heat
Other
Lead sponsor
Planned Parenthood of Greater New York
Other
Eligibility
16 Years to 51 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Brooklyn, New York
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Effect of Heat Pads and Foam Rolling on Strength in Athletes.

NCT07569601
Conditions
Healthy Participants
Interventions
Heating Pad, Foam Roller
Device
Lead sponsor
University of Redlands
Other
Eligibility
18 Years to 23 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Redlands, California
Conditions
Peripheral Arterial Disease, Intermittent Claudication
Interventions
Home-based leg heat therapy
Device
Lead sponsor
Purdue University
Other
Eligibility
60 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
West Lafayette, Indiana
Conditions
Back Strain, Neck Strain
Interventions
Heat, Cold
Other
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Stony Brook, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Radiofrequency Hyperthermia Safety Study

NCT05399771
Conditions
Chronic Pain, Soft Tissue Injuries, Wound Heal, Blood Flow
Interventions
Laser Doppler, Radiofrequency Heating System, Thermal Imaging, Healthcare Questionnaire & Measurement
Device · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Diabetes, Hypoglycemia
Interventions
hyperinsulinemic-hypoglycemic clamp, 13C-MRS procedure/Acetate infusion
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 40 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Baton Rouge, Louisiana