Independent directory Public ClinicalTrials.gov records United States
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Showing 145–168 of 464 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Accepts healthy volunteers

Cold Water Exposure and Immune Function Study

NCT06667479
Conditions
Cold Water Immersion, Immune Function, Muscular Strength, Mental Health
Interventions
Cold Water Immersion (CWI) - Cold Tub Immersion (CI), Cold Water Immersion (CWI) - Cold Shower (CS), Control Group (CO)
Other
Lead sponsor
University of Northern Colorado
Other
Eligibility
18 Years to 45 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Greeley, Colorado
Conditions
Obesity, Physical Activity, Cognitive Function 1, Social
Interventions
Flanker Test and physical fitness test
Other
Lead sponsor
University of Miami
Other
Eligibility
8 Years to 12 Years
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Breast Augmentation, Breast Reconstruction, Breast Revision
Interventions
The Contour Profile Gel (CPG) breast implants
Device
Lead sponsor
Mentor Worldwide, LLC
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,891 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Santa Barbara, California
Completed Not applicable Interventional Accepts healthy volunteers

Cold Water Exposure's Effects on Physical and Mental Health

NCT06667193
Conditions
Cold Exposure
Interventions
Cold Water Immersion (CWI) - Cold Tub Immersion (CI), Cold Water Immersion (CWI) - Cold Shower (CS)
Other
Lead sponsor
University of Northern Colorado
Other
Eligibility
18 Years to 45 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Greeley, Colorado
Terminated Phase 2 Interventional Results available

Neoadjuvant Chemoradiation for Resectable Glioblastoma

NCT04209790
Conditions
Glioblastoma, Surgery, High Grade Glioma
Interventions
Neoadjuvant chemoradiation, Drug Therapy with Temozolomide (benzolamide) (Standard of Care), Surgery post Radiation and Temozolomide (benzolamide)
Radiation · Drug · Procedure
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years to 89 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Danville, Pennsylvania • Wilkes-Barre, Pennsylvania
Recruiting Not applicable Interventional

Evaluation of the PPAL

NCT07221552
Conditions
Age Problems
Interventions
PPAL
Device
Lead sponsor
Alicia Koontz
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Terminated Phase 2Phase 3 Interventional Results available

Clinical Trial of Growth Hormone in MPS I, II, and VI

NCT00748969
Conditions
Mucopolysaccharidosis I, Mucopolysaccharidosis II, Mucopolysaccharidosis VI
Interventions
Somatropin (DNA origin)
Drug
Lead sponsor
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Other
Eligibility
5 Years to 17 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Minneapolis, Minnesota
Completed Not applicable Interventional Results available

Anterior Cruciate Ligament Reconstruction and Plyometric Exercise

NCT01851655
Conditions
Anterior Cruciate Ligament Reconstruction
Interventions
Plyometric Exercise
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
15 Years to 30 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Gainesville, Florida
Completed No phase listed Observational

Posturography Changes During Pregnancy

NCT03067116
Conditions
Pregnant Women
Interventions
Posturography Evaluation, Anthropometrics, Vitals, Health and daily activity questionnaires
Diagnostic Test · Other
Lead sponsor
Caps Research Network
Other
Eligibility
18 Years and older · Female only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Marietta, Georgia
Conditions
SGA, Turner Syndrome, Noonan Syndrome, ISS
Interventions
Somapacitan
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
10 Years to 18 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
6
States / cities
Birmingham, Alabama • Sacramento, California • Centennial, Colorado + 3 more
Not listed Not applicable Interventional Accepts healthy volunteers

D-Cycloserine-Enhancer of One-Session Treatment for Phobia of Heights

NCT01037101
Conditions
Height Phobia
Interventions
In Vivo Exposure Therapy, Virtual Reality Exposure Therapy, D-Cycloserine, Placebo
Behavioral · Drug
Lead sponsor
CAMC Health System
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Charleston, West Virginia
Conditions
Cerebral Palsy (CP)
Interventions
Physical Therapy Gait Training
Behavioral
Lead sponsor
Father Flanagan's Boys' Home
Other
Eligibility
16 Years to 30 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Omaha, Nebraska
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effect of Lycopene and Isoflavones on Glucose Metabolism

NCT01377961
Conditions
Metabolic Syndrome, Diabetes Mellitus, Non-Insulin-Dependent
Interventions
Randomized pills either containing combination of lycopene and isoflavones (dietary supplements) or Placebo to be taken for 12 weeks, Screening, OGTT, Anthropometrics and Blood pressure, Blood Drawing
Drug · Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
2
States / cities
Galveston, Texas
Conditions
Insulin-like Growth Factor-1 Deficiency
Interventions
NutropinAq® (Somatropin [rDNA origin]), Increlex® (Mecasermin [rDNA origin] injection) + NutropinAq® (Somatropin [rDNA origin])
Drug
Lead sponsor
Ipsen
Industry
Eligibility
5 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Brisbane, California
Conditions
ARDS, Critical Illness, Acute Respiratory Distress Syndrome, Acute Respiratory Failure
Interventions
Default order set, Physician-targeted accountable justification, Respiratory therapist (RT)-targeted accountable justification
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 99 Years
Enrollment
7,342 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
5
States / cities
Plainsboro, New Jersey • Philadelphia, Pennsylvania • West Chester, Pennsylvania
Conditions
Chronic Low Back Pain
Interventions
DRX9000
Device
Lead sponsor
NEMA Research, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
McAllen, Texas
Conditions
Metastatic Breast Cancer
Interventions
Docetaxel, Erythromycin Breath Test (ERMBT)
Drug · Procedure
Lead sponsor
University of Michigan Rogel Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2006
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Specific Phobia
Interventions
EXP, EXP + SBF, EXP + SBF + AA
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Austin, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Bioavailability of Berberine and Dihydroberberine and Their Impact on Glycemia

NCT05021341
Conditions
Glycemia
Interventions
Berberine, Dihydroberberine 200, Dihydroberberine 100, Placebo
Dietary Supplement
Lead sponsor
Lindenwood University
Other
Eligibility
18 Years to 45 Years · Male only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Saint Charles, Missouri
Conditions
Idiopathic Short Stature
Interventions
Not listed
Lead sponsor
BioMarin Pharmaceutical
Industry
Eligibility
2 Years to 16 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2040
U.S. locations
38
States / cities
Phoenix, Arizona • Los Angeles, California • Orange, California + 33 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

What is the Optimal Stiffness and Height of a Running-specific Prosthesis?

NCT02318979
Conditions
Amputation, Traumatic, Traumatic Amputation of Lower Extremity, Wounds and Injuries
Interventions
Otto Bock prosthesis, Ossur prosthesis, Freedom Innovations prosthesis
Device
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Boulder, Colorado
Withdrawn Not applicable Interventional Accepts healthy volunteers

Anabolic Response Cancer

NCT02793531
Conditions
Cancer
Interventions
Stable isotope amino acid infusion
Other
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
College Station, Texas
Conditions
Chronic Kidney Diseases
Interventions
Dietary education program
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Rochester, New York
Conditions
B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma
Interventions
Samalizumab
Drug
Lead sponsor
Alexion Pharmaceuticals, Inc.
Industry
Eligibility
Not listed
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
4
States / cities
Tucson, Arizona • Atlanta, Georgia • Morristown, New Jersey + 1 more