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Showing 1–24 of 393 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Hemoglobin A1c Clear all
Recruiting Phase 1 Interventional Accepts healthy volunteers

Alpelisib Challenge Test (ACT)

NCT07778524
View directory record Official record
Conditions
Insulin Resistance, Type 2 Diabetes, Obesity & Overweight, Healthy Adult Participants
Interventions
Alpelisib 300 mg, Alpelisib Challenge Test (ACT): Mixed Meal Tolerance Test (MMTT) after taking alpelisib, Hyperglycemic clamp
Drug · Diagnostic Test
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 6, 2026, 1:26 AM EDT
Completed No phase listed Observational Results available

Control-IQ Observational (CLIO) Post-Approval Study

NCT04503174
View directory record Official record
Conditions
Diabetes Mellitus, Type 1
Interventions
t:slim X2 pump with Control-IQ technology
Device
Lead sponsor
Tandem Diabetes Care, Inc.
Industry
Eligibility
6 Years and older
Enrollment
3,157 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 7, 2023 · Synced Sep 6, 2026, 1:26 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Non-interventional Pre-screening Protocol Aims to Evaluate Participants for Potential Trial Eligibility in Future Clinical Trials/Studies Focusing on Metabolic and Psychiatric Health.

NCT07106879
View directory record Official record
Conditions
Cardiovascular Diseases, Metabolic Syndrome, Obesity, Prediabetes, Mental Health Disorders, Endocrine Dysfunction, Type 2 Diabetes Mellitus (T2DM), Chronic Kidney Disease (CKD)
Interventions
Blood Work
Other
Lead sponsor
Clindove Research LLC
Other
Eligibility
18 Years and older
Enrollment
7,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Sep 6, 2026, 1:26 AM EDT
Completed Not applicable Interventional

Effect of Discontinuation of Sugar Sweetened Beverages

NCT00585897
View directory record Official record
Conditions
Type 2 Diabetes, Obesity
Interventions
discontinuation of sugar sweetened beverages
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 13, 2015 · Synced Sep 6, 2026, 1:26 AM EDT
Active, not recruiting Not applicable Interventional

Impact of Per Oral Pyloromyotomy (POP) on Glycemic Control in Diabetes

NCT04696159
View directory record Official record
Conditions
Diabetes Mellitus, Gastroparesis With Diabetes Mellitus, Gastroparesis
Interventions
Pyloromyotomy
Procedure
Lead sponsor
Matthew Allemang
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 6, 2026, 1:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

N2-(1-carboxyethyl)-2'Deoxyguanosine (CEdG) a Potential Biomarker for Diabetes

NCT02065310
View directory record Official record
Conditions
Diabetes
Interventions
N2-(1-carboxyethyl)-2'deoxyguanosine (CEdG)
Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Nov 4, 2019 · Synced Sep 6, 2026, 1:26 AM EDT
Completed Not applicable Interventional Results available

The Fasting II Study

NCT01792986
View directory record Official record
Conditions
Diabetes, Metabolic Diseases
Interventions
water-only 24-hour fasting once per week for 6 weeks
Behavioral
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
30 Years to 69 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
2
States / cities
Murray, Utah • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 19, 2017 · Synced Sep 6, 2026, 1:26 AM EDT
Completed Phase 1 Interventional

Acute Effects of Canagliflozin, a Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitor on Bone Metabolism in Healthy Volunteers

NCT02404870
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Placebo, Canagliflozin
Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2025 · Synced Sep 6, 2026, 1:26 AM EDT
Completed Not applicable Interventional

Diabetes Electronic Prompt for Improved Care Coordination and Treatment in the ED

NCT06899191
View directory record Official record
Conditions
Type 2 Diabetes, Type 2 Diabetes Mellitus (T2DM), Hyperglycemia, Insulin Dependent Diabetes
Interventions
Hemoglobin A1c, Observation Unit
Diagnostic Test · Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
21 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 6, 2026, 1:26 AM EDT
Completed Not applicable Interventional

Effect of Vitamin D Supplementation on Hemoglobin A1c in Patients With Uncontrolled Type 2 Diabetes Mellitus

NCT00985361
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Vitamin D3 2000 international units daily, Vitamin C 500mg daily
Dietary Supplement
Lead sponsor
ProMedica Health System
Other
Eligibility
21 Years to 75 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
3
States / cities
Sylvania, Ohio • Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated May 5, 2010 · Synced Sep 6, 2026, 1:26 AM EDT
Completed Not applicable Interventional

Improving Diabetes Care and Outcomes on the South Side of Chicago

NCT01087073
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Patient Activation, Provider Training, Quality Improvement, Community Outreach
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
6,209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
6
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Sep 6, 2026, 1:26 AM EDT
Completed Not applicable Interventional

An RCT Evaluation of a Diabetes Dashboard Team Model in Primary Care

NCT02156037
View directory record Official record
Conditions
Diabetes
Interventions
Diabetes Dashboard Intervention, Usual Diabetes Care
Behavioral
Lead sponsor
Baystate Medical Center
Other
Eligibility
18 Years and older
Enrollment
399 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 4, 2014 · Synced Sep 6, 2026, 1:26 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Best Practice Advisories to Reduce Inequities in Technology Use for People With Type 1 Diabetes

NCT06931275
View directory record Official record
Conditions
Diabetes Mellitus, Type 1
Interventions
EMR-based BPA model, Placebo (EMR-based without BPA model)
Other · Behavioral
Lead sponsor
T1D Exchange, United States
Other
Eligibility
2 Years to 95 Years
Enrollment
1,178 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Sep 6, 2026, 1:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Guide To Goals: A Novel Care Coordination Tool for Children With Type Two Diabetes (T2D)

NCT03926598
View directory record Official record
Conditions
Type2 Diabetes Mellitus
Interventions
Patient and/or Family Member Intervention, Certified Diabetes Educator Intervention, Physician Intervention, Front Desk Staff Intervention, Nurse Intervention
Behavioral
Lead sponsor
Georgia Institute of Technology
Other
Eligibility
12 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 5, 2023 · Synced Sep 6, 2026, 1:26 AM EDT
Completed Not applicable Interventional Results available

Complete Health Improvement Program for Geisinger Health Plan Members With Type 2 Diabetes

NCT04924400
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
CHIP Program, Usual Care
Behavioral
Lead sponsor
Thomas Morland
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Sep 6, 2026, 1:26 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Small Extracellular Vesicles and Insulin Action

NCT05933707
View directory record Official record
Conditions
Obesity, Insulin Resistance, Metabolically Healthy Obesity, Obesity, Metabolically Benign
Interventions
People with Metabolically Unhealthy Obesity - Low Calorie Diet
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
25 Years to 55 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 6, 2026, 1:26 AM EDT
Not listed Not applicable Interventional

Peer-led and Telehealth Comparative Effectiveness Research (CER) Adoption for Diabetes Prevention and Management

NCT01307137
View directory record Official record
Conditions
Diabetes, Pre-diabetes
Interventions
Peer-led intervention, Telehealth Intervention
Behavioral
Lead sponsor
South Florida Veterans Affairs Foundation for Research and Education
Federal
Eligibility
60 Years and older
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 1, 2011 · Synced Sep 6, 2026, 1:26 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Neulasta in Type 1 Diabetes

NCT00662519
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Neulasta (Pegylated), Placebo, Mixed Meal Tolerance Test (MMTT), Blood test, DNA Test
Drug · Dietary Supplement · Other
Lead sponsor
University of Florida
Other
Eligibility
12 Years to 45 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 8, 2015 · Synced Sep 6, 2026, 1:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adolescent Self-Care and Knowledge Education in Diabetes--Improved by Texting

NCT03241212
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
Texting
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
15 Years to 21 Years
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 2, 2019 · Synced Sep 6, 2026, 1:26 AM EDT
Terminated Not applicable Interventional

Novel Digital Patient-Reported Outcomes Tool for Diabetes Management

NCT05884775
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Mobile Health (mHealth) Patient-Reported Outcome (PRO) tool
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 6, 2026, 1:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Models of Nutrition From Continuous Glucose Monitors

NCT04991142
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Pre-diabetes, Diet Habit, Diet, Healthy
Interventions
Not listed
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Santa Barbara, California • College Station, Texas
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Sep 6, 2026, 1:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Impact of Pancreatic Islet Cell Allotransplantation on Cognitive Function in Type 1 Diabetes Mellitus

NCT00590876
View directory record Official record
Conditions
Diabetes Mellitus, Type 1
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
2
States / cities
New Haven, Connecticut • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 26, 2011 · Synced Sep 6, 2026, 1:26 AM EDT
Completed Phase 3 Interventional Results available

Safety and Efficacy of Bexagliflozin in Type 2 Diabetes Mellitus Patients With Moderate Renal Impairment

NCT02836873
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Bexagliflozin, Placebo
Drug
Lead sponsor
Theracos
Industry
Eligibility
20 Years and older
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
23
States / cities
Fresno, California • La Palma, California • Lincoln, California + 19 more
Source: ClinicalTrials.gov public record
Updated Jun 29, 2021 · Synced Sep 6, 2026, 1:26 AM EDT
Completed Phase 3 Interventional

Study to Examine the Effect on Glucose Control and Safety/Tolerability of Exenatide Given Two Times a Day to Subjects With Type 2 Diabetes

NCT00111540
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
exenatide
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 70 Years
Enrollment
456 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
60
States / cities
Birmingham, Alabama • Anaheim, California • Bellflower, California + 57 more
Source: ClinicalTrials.gov public record
Updated Feb 22, 2015 · Synced Sep 6, 2026, 1:26 AM EDT