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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Hemoglobin A1c Clear all
Recruiting No phase listed Observational Accepts healthy volunteers

Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)

NCT05277558
View directory record Official record
Conditions
Type2 Diabetes, Type 2 Diabetes Mellitus in Obese, Dysglycemia, Microvascular Complications, Brain Structure, Obesity, Childhood, Diabetes in Adolescence, Inflammation, Insulin Resistance, Overweight, Childhood, Cognitive Decline
Interventions
Observational
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years to 17 Years
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
2
States / cities
St Louis, Missouri • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Sep 26, 2026, 10:45 AM EDT
Completed Not applicable Interventional

Addressing Disparities in Diabetes Care

NCT06643611
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Continuous Glucose Monitor, Usual Care
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 2, 2025 · Synced Sep 26, 2026, 10:45 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Randomized Controlled Clinical Trial of Cinnamon to Lower Hemoglobin A1c

NCT00445354
View directory record Official record
Conditions
Diabetes
Interventions
cinnamon
Drug
Lead sponsor
Eglin AFB Regional Hospital
Federal
Eligibility
18 Years to 90 Years
Enrollment
109 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Eglin Air Force Base, Florida
Source: ClinicalTrials.gov public record
Updated Feb 6, 2019 · Synced Sep 26, 2026, 10:45 AM EDT
Terminated Phase 3 Interventional

Effect of Inhaled Pre-prandial Human Insulin on Blood Glucose Control in Type 2 Diabetes

NCT00427154
View directory record Official record
Conditions
Diabetes, Diabetes Mellitus, Type 2
Interventions
rosiglitazone, inhaled human insulin, metformin, glimepiride
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
227 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
103
States / cities
Hueytown, Alabama • Ozark, Alabama • Tuscaloosa, Alabama + 95 more
Source: ClinicalTrials.gov public record
Updated Sep 4, 2018 · Synced Sep 26, 2026, 10:45 AM EDT
Recruiting Not applicable Interventional

Preventative Screening and Health Coaching in a Food Insecure Population

NCT06907524
View directory record Official record
Conditions
Cardiovascular Disease Prevention, Cardiometabolic Diseases, Cardiovascular Risk Factor, Cardiovascular Risk Score, Hypertension, Hyperlipidemia, Diabetes, Lifestyle Modification, Health Coaching
Interventions
Longitudinal, Individualized Health Coaching
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
40 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 26, 2026, 10:45 AM EDT
Completed Phase 3 Interventional

Efficacy/Safety of Vildagliptin and Metformin Combination Therapy in Patients With Type 2 Diabetes Not Well Controlled With Metformin Alone

NCT00396357
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Vildagliptin, metformin
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 78 Years
Enrollment
914 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
1
States / cities
East Hanover, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 16, 2020 · Synced Sep 26, 2026, 10:45 AM EDT
Completed Not applicable Interventional

Precision Clinical and Genetic Tools for Brain Health in Hemorrhagic Stroke

NCT05643001
View directory record Official record
Conditions
Hemorrhagic Stroke
Interventions
In-patient and out-patient electronic health record alert
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Sep 26, 2026, 10:45 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Patient Coach Support for Older Adults With Obesity

NCT06624163
View directory record Official record
Conditions
Obesity
Interventions
OHWL Clinic Activities (Standard of Care), Coach Activities
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
60 Years to 85 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Sep 26, 2026, 10:45 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Early Investigation of Glucose Monitoring After Gestational Diabetes Pilot

NCT06184373
View directory record Official record
Conditions
Gestational Diabetes, Hyperglycemia
Interventions
Continuous glucose monitor, Oral Glucose Tolerance Test, Hemoglobin A1c
Device · Diagnostic Test
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Sep 26, 2026, 10:45 AM EDT
Completed Phase 2 Interventional

Abatacept Conversion in Kidney Transplantation

NCT04955366
View directory record Official record
Conditions
Renal Transplant Recipient
Interventions
Belatacept, Abatacept
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Sep 26, 2026, 10:45 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Impact of Hypoglycemia Unawareness on Brain Metabolism Cognition in T1DM

NCT00575783
View directory record Official record
Conditions
Type 1 Diabetes, Hypoglycemia
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
18 Years to 49 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 1, 2020 · Synced Sep 26, 2026, 10:45 AM EDT
Recruiting Not applicable Interventional

Culturally Tailored Program for Food-Insecure Adults: SPICE-D

NCT07361341
View directory record Official record
Conditions
Type 2 Diabetes Mellitus (T2D)
Interventions
Food Bundle Intervention
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 26, 2026, 10:45 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Best Practice Advisories to Reduce Inequities in Technology Use for People With Type 1 Diabetes

NCT06931275
View directory record Official record
Conditions
Diabetes Mellitus, Type 1
Interventions
EMR-based BPA model, Placebo (EMR-based without BPA model)
Other · Behavioral
Lead sponsor
T1D Exchange, United States
Other
Eligibility
2 Years to 95 Years
Enrollment
1,178 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Sep 26, 2026, 10:45 AM EDT
Terminated Not applicable Interventional Results available

Protege Extension Trial - Long Term Follow Up Trial for Subjects Who Completed the Protege Study (CP-MGA031-01)

NCT00870818
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
Blood samples for safety, Patient reported outcome questionnaires, Analysis of T-cell subsets
Diagnostic Test · Behavioral
Lead sponsor
MacroGenics
Industry
Eligibility
10 Years to 37 Years
Enrollment
219 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 8, 2023 · Synced Sep 26, 2026, 10:45 AM EDT
Completed Phase 2 Interventional Results available

Dose-Ranging Study In Subjects With Type 2 Diabetes Mellitus Who Are Treatment-Naive

NCT00495469
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
GSK189075, Placebo
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 70 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
65
States / cities
Mesa, Arizona • Artesia, California • Buena Park, California + 54 more
Source: ClinicalTrials.gov public record
Updated Oct 29, 2017 · Synced Sep 26, 2026, 10:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Case-Management Using Home Monitoring on Diabetes and Blood Pressure Outcomes

NCT00935441
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
case management with telemonitoring, usual case management
Behavioral
Lead sponsor
Minneapolis Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
460 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 15, 2011 · Synced Sep 26, 2026, 10:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study on Biomarkers of Periodontitis and Type 2 Diabetes Mellitus in Males and Females 30 - 70 Years of Age

NCT06582056
View directory record Official record
Conditions
Periodontal Disease
Interventions
Investigational Procedure
Procedure
Lead sponsor
Sanofi Pasteur, a Sanofi Company
Industry
Eligibility
30 Years to 70 Years
Enrollment
226 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
4
States / cities
Iowa City, Iowa • Somerville, Massachusetts • Stony Brook, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 27, 2025 · Synced Sep 26, 2026, 10:45 AM EDT
Terminated Phase 3 Interventional

Effects of Pulsed Intravenous (IV) Insulin on Brittle and Uncontrolled Diabetes

NCT01029444
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Pulsatile Intravenous Insulin Therapy (Humulin, Humulog, Novolog )
Procedure
Lead sponsor
Florida Atlantic University
Other
Eligibility
18 Years to 85 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Boca Raton, Florida
Source: ClinicalTrials.gov public record
Updated Feb 2, 2016 · Synced Sep 26, 2026, 10:45 AM EDT
Active, not recruiting Not applicable Interventional

Fully Closed Loop At Home (FCL@Home)

NCT06041971
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
AIDANET system
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
14 Years to 60 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
3
States / cities
San Francisco, California • Aurora, Colorado • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 17, 2024 · Synced Sep 26, 2026, 10:45 AM EDT
Recruiting Not applicable Interventional

Early Detection of Gestational Diabetes Mellitus in Pregnancy

NCT05388643
View directory record Official record
Conditions
Gestational Diabetes Mellitus in Pregnancy, Pregnancy, High Risk
Interventions
Enhanced First Trimester GDM Screening, Routine Gestational Diabetes Screening
Diagnostic Test
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Sep 26, 2026, 10:45 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Liraglutide in the Treatment of Type 1 Diabetes Mellitus

NCT01722266
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Liraglutide, Placebo
Drug
Lead sponsor
University at Buffalo
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Williamsville, New York
Source: ClinicalTrials.gov public record
Updated Jan 4, 2024 · Synced Sep 26, 2026, 10:45 AM EDT
Completed Phase 3 Interventional Results available

6-month Comparison of Morning Lantus Versus Neutral Protamine Hagedorn Insulin in Young Children With Type 1 Diabetes

NCT00993473
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
Insulin glargine (HOE901), Neutral Protamine Hagedorn (NPH) insulin, Insulin lispro
Drug
Lead sponsor
Sanofi
Industry
Eligibility
1 Year to 6 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
8
States / cities
Sacramento, California • San Diego, California • Greenwood Village, Colorado + 5 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2012 · Synced Sep 26, 2026, 10:45 AM EDT
Completed Phase 2 Interventional

Effect of Vitamin D Supplementation on Hemoglobin A1c

NCT01354262
View directory record Official record
Conditions
Diabetes Mellitus, Vitamin D Deficiency
Interventions
Vitamin D
Dietary Supplement
Lead sponsor
Ascension Health
Industry
Eligibility
34 Years to 69 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 22, 2015 · Synced Sep 26, 2026, 10:45 AM EDT
Terminated Phase 3 Interventional Results available

To Evaluate the Effect of Liraglutide Versus Glimepiride (Amaryl®) on Haemoglobin A1c

NCT00294723
View directory record Official record
Conditions
Diabetes, Diabetes Mellitus, Type 2
Interventions
liraglutide, glimepiride, placebo
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years to 80 Years
Enrollment
746 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
102
States / cities
Concord, California • Escondido, California • Fullerton, California + 83 more
Source: ClinicalTrials.gov public record
Updated Mar 6, 2017 · Synced Sep 26, 2026, 10:45 AM EDT