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ClinicalTrials.gov public records Last synced Oct 6, 2026, 2:14 PM EDT

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Showing 49–72 of 254 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Hernia repair Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Mesh Removal Versus No Mesh Removal for Chronic Groin Pain After Inguinal Hernia Repair

NCT05484635
View directory record Official record
Conditions
Chronic Groin Pain, Hernia, Inguinal
Interventions
Diagnostic laparoscopy and inguinal mesh removal, Diagnostic laparoscopy
Procedure
Lead sponsor
David Krpata
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Oct 6, 2026, 2:14 PM EDT
Terminated Phase 2 Interventional Results available

Feasibility of Permacol Use in Infected Fields

NCT00820040
View directory record Official record
Conditions
Hernia
Interventions
acellular porcine dermal collagen mesh
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
3
States / cities
Lexington, Kentucky • Albany, New York • Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 9, 2020 · Synced Oct 6, 2026, 2:14 PM EDT
Not yet recruiting Not applicable Interventional

Low Pressure Pneumoperitoneum Using AirSeal® for Reduction in Postoperative Shoulder Pain Following Robot Assisted Hiatal Hernia Repair

NCT06737068
View directory record Official record
Conditions
Hernia, Hiatal, Pneumoperitoneum, Postoperative Pain, Shoulder Pain
Interventions
Low pressure pneumoperitoneum (8-10mmHg) with AirSeal device, Standard pressure pneumoperitoneum (13- 15 mmHg) with AirSeal device
Procedure
Lead sponsor
Riverside University Health System Medical Center
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Moreno Valley, California
Source: ClinicalTrials.gov public record
Updated Dec 17, 2024 · Synced Oct 6, 2026, 2:14 PM EDT
Completed No phase listed Observational Results available

Complications, Outcomes and Revisions Following Hiatal Hernia Repair With MIROMESH

NCT03735862
View directory record Official record
Conditions
Hiatal Hernia With Gastroesophageal Reflux Disease, Gastroesophageal Reflux, GERD
Interventions
Hepatic derived surgical matrix
Biological
Lead sponsor
Miromatrix Medical Inc.
Industry
Eligibility
Not listed
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Lorton, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 1, 2019 · Synced Oct 6, 2026, 2:14 PM EDT
Completed No phase listed Observational

Long-term Outcome of Laparoscopic Hiatal Hernia Repair With or Without Alloderm Mesh at a University Hospital

NCT01776827
View directory record Official record
Conditions
Gastroesophageal Reflux Disease, Hiatal Hernia, Paraesophageal Hernia
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 5, 2023 · Synced Oct 6, 2026, 2:14 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Improving Pain Control in Paraesophageal Hernia Repair: Intravenous Lidocaine Versus Placebo

NCT04096170
View directory record Official record
Conditions
Hernia, Paraesophageal
Interventions
IV lidocaine, Placebo
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 6, 2026, 2:14 PM EDT
Terminated Not applicable Interventional

Freedom Inguinal Hernia Repair System Study

NCT01984996
View directory record Official record
Conditions
Primary Inguinal Hernia
Interventions
Freedom ProFlor Inguinal Hernia Implant
Device
Lead sponsor
Insightra Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
4
States / cities
Los Angeles, California • Lebanon, Indiana • Baton Rouge, Louisiana + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2016 · Synced Oct 6, 2026, 2:14 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Detection of Peritoneal Micrometastasis in Gastric and Pancreatic Cancer in Peritoneal Wash Samples

NCT00582062
View directory record Official record
Conditions
Gastric and Pancreatic Cancer
Interventions
washings for experimental marker testing
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 6, 2023 · Synced Oct 6, 2026, 2:14 PM EDT
Completed No phase listed Observational

Comparative Effectiveness Multicenter Trial for Adhesion Characteristics of Ventral Hernia Repair Mesh

NCT01355939
View directory record Official record
Conditions
Ventral Hernia, Adhesions
Interventions
Clinically-Indicated Abdominal Re-Exploration Surgery
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
6
States / cities
Phoenix, Arizona • San Diego, California • Springfield, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 23, 2015 · Synced Oct 6, 2026, 2:14 PM EDT
Completed Not applicable Interventional

Characterizing Stray Energy Injuries During Robotic Surgery

NCT03477201
View directory record Official record
Conditions
Port-site Injury Caused by Stray Energy Transfer
Interventions
Laparoscopic robotic DaVinci assisted inguinal hernia repair, Standard laparoscopic inguinal hernia repair
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
Male only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 1, 2024 · Synced Oct 6, 2026, 2:14 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Epidural Anesthesia /Analgesia Versus PCA for Laparoscopic Complex Ventral Hernia Repair: A Randomized Controlled Trial

NCT00529074
View directory record Official record
Conditions
Analgesia
Interventions
Epidural Catheter for Analgesia
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 16, 2016 · Synced Oct 6, 2026, 2:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparing eTEP and Laparoscopic Intraperitoneal Onlay Mesh (IPOM) for Ventral Hernias

NCT04150796
View directory record Official record
Conditions
Ventral Hernia, Umbilical Hernia, Epigastric Hernia
Interventions
Ventral Hernia Repair
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 4, 2023 · Synced Oct 6, 2026, 2:14 PM EDT
Recruiting Not applicable Interventional

A Prospective, Single-Center Investigation of the da Vinci SP® Surgical System in Hepatopancreaticobiliary and Foregut Operations for Benign and Malignant Disease

NCT06562179
View directory record Official record
Conditions
Hepatopancreaticobiliary and Foregut Operations
Interventions
da Vinci SP® Single-Port Robotic Surgical System
Device
Lead sponsor
AdventHealth
Other
Eligibility
18 Years to 80 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 6, 2026, 2:14 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Transabdominal Plane (TAP) Blocks for Inguinal Hernia Repairs

NCT05672680
View directory record Official record
Conditions
Inguinal Hernia
Interventions
0.25% Bupivacaine, Placebo, TAP block
Drug · Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 28, 2025 · Synced Oct 6, 2026, 2:14 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Short Term Outcomes of Heavy-weight Versus Medium-weight Synthetic Mesh

NCT06409091
View directory record Official record
Conditions
Hernia, Ventral, Hernia Incisional
Interventions
Medium weight or Heavy weight mesh
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
1,496 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 14, 2024 · Synced Oct 6, 2026, 2:14 PM EDT
Completed Phase 2 Interventional Results available

Efficacy, Safety and Pharmacokinetic Profile of a Collagen Bupivacaine Implant in Men After Open Mesh Herniorrhaphy

NCT00626886
View directory record Official record
Conditions
Postoperative Pain, Inguinal Hernia
Interventions
Bupivacaine Collagen Sponge, placebo collagen sponge
Drug
Lead sponsor
Innocoll
Industry
Eligibility
18 Years and older · Male only
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Anaheim, California
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Oct 6, 2026, 2:14 PM EDT
Withdrawn Not applicable Interventional

Microlyte in Prevention of SSI After Open Ventral Hernia Repair

NCT05093894
View directory record Official record
Conditions
Ventral Hernia
Interventions
Group 1
Device
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
3
States / cities
Asheville, North Carolina • Charlotte, North Carolina • Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 10, 2022 · Synced Oct 6, 2026, 2:14 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Robotic Versus Open Ventral Hernia Repair

NCT05472987
View directory record Official record
Conditions
Ventral Hernia
Interventions
Ventral Hernia Repair
Procedure
Lead sponsor
Lucas Beffa
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
5
States / cities
Gainesville, Florida • Cleveland, Ohio • Greenville, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 6, 2026, 2:14 PM EDT
Terminated No phase listed Observational

LINX Reflux Management System or Fundoplication Clinical Study in Patients With Hiatal Hernia >3 cm

NCT04695171
View directory record Official record
Conditions
Hiatal Hernia Large, Gastro Esophageal Reflux, Hiatal Hernia, Hiatal Hernia, Paraesophageal, Reflux, Gastroesophageal, Reflux Acid
Interventions
LINX Reflux Management System, Fundoplication
Device · Procedure
Lead sponsor
Foregut Research Foundation
Other
Eligibility
21 Years and older
Enrollment
336 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
6
States / cities
Los Angeles, California • Lone Tree, Colorado • Coral Springs, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 6, 2026, 2:14 PM EDT
Completed Phase 3 Interventional Results available

Reducing INfection at the Surgical SitE With Antibiotic Irrigation During Ventral Hernia Repair (RINSE Trial)

NCT03945357
View directory record Official record
Conditions
Ventral Hernia Repair
Interventions
Gemcitabine/ clindamycin, Normal saline
Drug
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 24, 2023 · Synced Oct 6, 2026, 2:14 PM EDT
Not listed Phase 3 Interventional

Does Preoperative Caldolor Decrease the Requirement for Postoperative Narcotics

NCT01297829
View directory record Official record
Conditions
Postoperative Pain
Interventions
Intravenous Ibuprofen, IV Placebo
Drug · Other
Lead sponsor
St. Barnabas Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Livingston, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 16, 2014 · Synced Oct 6, 2026, 2:14 PM EDT
Terminated No phase listed Observational

A Study of Complex Ventral Hernia Repair Utilizing the XenMatrix™ Surgical Graft With Component Separation

NCT01305486
View directory record Official record
Conditions
Hernia
Interventions
Not listed
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 15, 2013 · Synced Oct 6, 2026, 2:14 PM EDT
Completed Phase 2 Interventional Results available

Phase 2 Herniorrhaphy Study for Opioid Elimination

NCT03695367
View directory record Official record
Conditions
Postoperative Pain
Interventions
HTX-011, Luer lock applicator, Vial access device, Ibuprofen, Acetaminophen, Ketorolac
Drug · Device
Lead sponsor
Heron Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
5
States / cities
Anaheim, California • Pasadena, California • Draper, Utah + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Oct 6, 2026, 2:14 PM EDT
Terminated Not applicable Interventional Results available

SERI® Surgical Scaffold Postmarket Study of Soft Tissue Support in Ventral Hernia Repair

NCT01981044
View directory record Official record
Conditions
Ventral Hernia Repair
Interventions
Silk surgical mesh
Device
Lead sponsor
Sofregen Medical, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 26, 2022 · Synced Oct 6, 2026, 2:14 PM EDT