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ClinicalTrials.gov public records Last synced Nov 5, 2026, 9:16 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1177–1200 of 2,754 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: High Activity Clear all

Conditions: Pediatric Cancer, Neuroblastoma, Sarcoma, Wilms Tumor and Other Childhood Kidney Tumors, Childhood Soft Tissue Sarcoma, Childhood Bone Sarcoma, Childhood Malignant Intestinal Neoplasm, Childhood Malignant Liver Neoplasm, Childhood Malignant Lung Neoplasm, Childhood Malignant Ovarian Neoplasm, Childhood Malignant Pleural Neoplasm, Childhood Neuroblastic Tumor, Childhood Sarcoma
Interventions: Wearing Smartwatch, Patient Report Outcomes, Blood Draw, Clinical Data Review; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 3 Years to 25 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Obesity, Overweight, Fatty Liver, Metabolic Syndrome X
Interventions: Almond, Cereal Bar; Dietary Supplement
Lead sponsor: Columbia University; Other
Eligibility: 30 Years to 65 Years
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Diabetes type1
Interventions: AG019 - Low Dose, Teplizumab, Placebo-AG019, Placebo-Teplizumab, AG019 - High Dose; Biological · Drug
Lead sponsor: Precigen Actobio T1D, LLC; Industry
Eligibility: 12 Years to 40 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 15
States / cities: Birmingham, Alabama • San Francisco, California • Ventura, California + 12 more

Conditions: Non-small Cell Lung Cancer
Interventions: Durvalumab, Monalizumab, Oleclumab, Radiotherapy; Drug · Radiation
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Breast Cancer
Interventions: Exercise Intervention; Other
Lead sponsor: Dana-Farber Cancer Institute; Other
Eligibility: 18 Years to 50 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Ehlers-Danlos Syndrome Hypermobility Type (hEDS)
Interventions: 3D scanned and 3D printed wrist hand orthosis; Device
Lead sponsor: ELewis; Other
Eligibility: 21 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Lowell, Massachusetts

Conditions: Obesity, Inflammation, Human Microbiome, Insulin Resistance, Dyslipidemias
Interventions: Omega-3 polyunsaturated fatty acid, High-Intensity Interval Training, Safflower oil, Low-intensity training; Dietary Supplement · Behavioral
Lead sponsor: Texas Tech University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 129 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Lubbock, Texas

Conditions: Ketogenic Diet, Exercise
Interventions: Diet, Exercise; Other · Behavioral
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years to 45 Years
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Laryngeal Dystonia
Interventions: neurofeedback brain-computer interface (BCI); Device
Lead sponsor: Kristina Simonyan; Other
Eligibility: 18 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Drive, Recidivism, Communication, Feedback, Psychological
Interventions: In-vehicle device, Parent Communication; Combination Product · Behavioral
Lead sponsor: Ginger Yang; Other
Eligibility: 16 Years to 17 Years
Enrollment: 240 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Skin Laxity (Submental and Neck), Facial Skin Laxity, Submental Tissue Laxity
Interventions: ULTRAFORMER MPT PLUS, Ulthera System; Device
Lead sponsor: CLASSYS Inc.; Industry
Eligibility: 30 Years to 65 Years
Enrollment: 273 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 5
States / cities: Los Angeles, California • Charlotte, North Carolina • Wilmington, North Carolina + 2 more

Conditions: Hypertension
Interventions: irbesartan, placebo, PS433540; Drug
Lead sponsor: Ligand Pharmaceuticals; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 261 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 40
States / cities: Pell City, Alabama • Tempe, Arizona • Tucson, Arizona + 36 more

Conditions: Complex Regional Pain Syndrome
Interventions: BRC-002, BRC-002 Placebo; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 21 Years to 75 Years
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 2
States / cities: La Jolla, California • San Diego, California

Conditions: Pain, Pregnancy
Interventions: painDETECT Questionnaire, Pain Catastrophizing Scale, Pain Intensity Scale, Pain Interference Scale, Pain Behavior Scale, Beck Depression Inventory, Visual Analogue Scale, Patient's Global Impression of Change Scale & Clinical Global Impression-Global Improvement Scale, Transcranial Magnetic Stimulation; Behavioral · Device
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Obesity, Overweight, Weight Loss, Health Behavior, Lifestyle Intervention
Interventions: Core Behavioral Weight Loss Intervention, Limit Red Zone Foods, Limit Eating Window, Increase Protein, Increase Fiber Intake; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 208 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Advanced Solid Malignant Tumors, Advanced Ovarian Cancer
Interventions: U3-1565; Drug
Lead sponsor: Daiichi Sankyo; Industry
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 4
States / cities: Detroit, Michigan • Oklahoma City, Oklahoma • Philadelphia, Pennsylvania + 1 more

Conditions: Hypertension, High Blood Pressure, Ventricular Hypertrophy, Diastolic Dysfunction, Systolic Dysfunction
Interventions: Exercise, Weight Loss, Low Sodium Diet, Smoking Cessation, Pharmaceutical Therapy (no specific therapy; approach guided by the JNC 7 protocol guidelines); Behavioral · Drug
Lead sponsor: Wayne State University; Other
Eligibility: 35 Years to 75 Years
Enrollment: 123 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Cardiovascular Diseases, Heart Diseases
Interventions: Not listed
Lead sponsor: Stanford University; Other
Eligibility: 65 Years and older
Enrollment: 896 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2009
U.S. locations: 2
States / cities: San Diego, California • Stanford, California

Conditions: Obese, Nondiabetic
Interventions: Weight loss; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 21 Years and older · Female only
Enrollment: 245 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Breast Cancer Female
Interventions: Supervised Exercise, Home-based Exercise, Reduced Energy Diet, Group Phone Calls; Behavioral
Lead sponsor: Carol Fabian, MD; Other
Eligibility: 50 Years to 70 Years · Female only
Enrollment: 11 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Lung Diseases, Interstitial
Interventions: Actigraph CP Insight Watch; Diagnostic Test
Lead sponsor: University of South Florida; Other
Eligibility: 40 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Carcinoma, Hepatocellular
Interventions: Atezolizumab, Bevacizumab; Drug
Lead sponsor: Hoffmann-La Roche; Industry
Eligibility: 18 Years and older
Enrollment: 668 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 8
States / cities: Los Angeles, California • Baltimore, Maryland • Detroit, Michigan + 5 more

Conditions: Spinal Cord Injuries
Interventions: Seated control (CON), Moderate intensity continuous (MICT), High intensity interval training (HIIT), Circuit resistance training (CRT), Liquid Meal; Behavioral · Other
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Suicide Prevention
Interventions: Virtual Crisis Response Planning, In-Person Crisis Response Planning, Crisis Risk Counseling; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 14 Years to 18 Years
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Columbus, Ohio

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Biomarkers of Resiliency In Childhood Cancer Surgery

Impact of Almond Supplementation on Body Composition in Overweight/Obese Minority Adults

A Study to Assess the Safety and Tolerability of Different Doses of AG019 Administered Alone or in Combination With Teplizumab in Participants With Recent-onset Diagnosed Type 1 Diabetes (T1D)

The Selective Personalized Radio-Immunotherapy for Locally Advanced Non-Small Cell Lung Cancer Trial 2

Physical Activity, Proliferation and Immune Markers in Benign Breast Tissue

3D Printed Orthosis for Wrist Instability for Ehlers-Danlos Syndrome Patient

Combining HIIT and n-3 PUFA to Reduce Inflammation and Improve Metabolic Health

High Fat Meal and Postprandial TG Levels With and Without Exercise Intervention

Brain-Computer Interfaces in Laryngeal Dystonia

Intervention to Improve Driving Practices Among High-Risk Teen Drivers

Safety and Effectiveness Evaluation of the High-intensity Focused Ultrasound Device for Lifting Lax Submental and Neck Tissue

A Study To Evaluate The Dose-Related Efficacy and Safety of PS433540 in Subjects With Hypertension

The Effects and Mechanisms of a High CBD Cannabis Extract (BRC-002) for the Treatment of Pain and Health in Complex Regional Pain Syndrome

Neuropathic Pain in Pregnancy

Reset: Enhancing Weight Loss in a Digital Intervention

Study to Assess the Safety and Tolerability of U3-1565 in Subjects With Advanced Solid Malignant Tumors

Pre-clinical Cardiac Dysfunction Among Asymptomatic Hypertensive Patients

Understanding the Impact of Neighborhood Type on Physical Activity in Older Adults

Metabolism, Exercise and Nutrition at UCSD (MENU Study)

High Physical Activity During a Weight Loss Intervention for Breast Cancer Survivors and High Risk Women

Physical Activity and Quality of Life in Fibrotic Lung Diseases After Initiating Anti-fibrotic Therapy and Pulmonary Rehabilitation

A Study of Atezolizumab Plus Bevacizumab Versus Active Surveillance as Adjuvant Therapy in Patients With Hepatocellular Carcinoma at High Risk of Recurrence After Surgical Resection or Ablation

Energetic Response to Feeding and Exercise in SCI

Feasibility Trial of a Single Session of Crisis Response Planning for Youth at High Risk for Suicide