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ClinicalTrials.gov public records Last synced Nov 10, 2026, 7:07 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1945–1968 of 2,761 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: High Activity Clear all

Conditions: Alzheimer's Disease
Interventions: Repetitive Transcranial Magnetic Stimulation (rTMS), NICE Cognitive Training; Device · Behavioral
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 55 Years to 90 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression / Major Depressive Disorder, Mood, Sleep, Physical Activity
Interventions: Intern Health Study behavioral change mobile notification; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Low Back Pain
Interventions: HVLA-SM, LVVA-SM, Usual Medical Care; Other
Lead sponsor: Palmer College of Chiropractic; Other
Eligibility: 21 Years to 55 Years
Enrollment: 192 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Davenport, Iowa

Conditions: Stress, Emotional, Stress, Psychological, Behavioral Symptoms
Interventions: Technology Based Distractions; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 2 Years to 18 Years
Enrollment: 291 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Breast Cancer, Healthy, no Evidence of Disease
Interventions: exercise intervention, counseling intervention, gas chromatography, immunoenzyme technique, immunologic technique, laboratory biomarker analysis, mass spectrometry, physiologic testing, questionnaire administration, survey administration, dual x-ray absorptometry, magnetic resonance imaging, study of high risk factors; Behavioral · Other · Procedure
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: 18 Years to 35 Years · Female only
Enrollment: 183 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2016
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Hemodynamic Monitoring
Interventions: invasive Hemodynamic monitoring via Clearsight/Nexfin Systems from Edwards Lifesciences, No Hemodynamic Monitored Guided Assesment; Device
Lead sponsor: Loma Linda University; Other
Eligibility: 18 Years and older
Enrollment: 189 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 3
States / cities: Loma Linda, California

Conditions: Hypertension
Interventions: Spinal Manipulation, Sham Spinal Manipulation; Other
Lead sponsor: Palmer College of Chiropractic; Other
Eligibility: 21 Years to 75 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Davenport, Iowa

Conditions: Dry Needling
Interventions: Delphi Questionaire; Other
Lead sponsor: Youngstown State University; Other
Eligibility: 18 Years to 100 Years
Enrollment: 39 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Youngstown, Ohio

Conditions: Bipolar I Disorder, Depression
Interventions: Cariprazine, Aripiprazole/Escitalopram combination, Quetiapine, Lurasidone; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 75 Years
Enrollment: 2,726 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2030
U.S. locations: 17
States / cities: Birmingham, Alabama • Bloomington, Indiana • Baltimore, Maryland + 13 more

Conditions: Healthy, Brain Stimulation, Transcranial Direct Current Stimulation (tDCS), Cognition, Psychomotor Performance, Neurophysiology
Interventions: Active Transcranial Electrical Stimulation, Sham Transcranial Electrical Stimulation; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 25 Years to 55 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Charlestown, Massachusetts

Conditions: ME/CFS, ME/CFS Following EBV-associated Infectious Mononucleosis, ME/CFS Following COVID-19, Chronic Fatigue, Chronic Fatigue Syndrome (CFS), Brain Fog, Cognitive Impairment, Cognitive Dysfunction
Interventions: Processing Speed Training, In-session Instrumental Activities of Daily Living Training, Transfer Package, Follow Up Phone Calls, Trans-auricular Vagus Nerve Stimulation: High Intensity, In-session Brain Health Training, Reaction Time Training, Trans-auricular Vagus Nerve Stimulation: Low Intensity; Behavioral · Procedure
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: HIV Infections
Interventions: Interleukin 2, HAART, Treatment interruption; Drug
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years and older
Enrollment: 148 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2007
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Ovarian Cancer
Interventions: TUB-040 + Carbo + BEV; Drug
Lead sponsor: Gilead Sciences; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 3
States / cities: Los Angeles, California • East Brunswick, New Jersey • New York, New York

Conditions: Transcranial Electric Stimulation
Interventions: TES-TI with hdEEG; Device
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 50 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Prediabetes, Healthy (Controls)
Interventions: Ketone Monoester (KE), Placebo; Dietary Supplement
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 60 Years to 75 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: Birmingham, Alabama

Conditions: PreDiabetes, Overweight and Obesity, Type 2 Diabetes, Overweight, Childhood, Obesity, Childhood, Lifestyle, Healthy
Interventions: National Diabetes Prevention Program Lifestyle Intervention (DPP), Family Diabetes Prevention Program (Family DPP); Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 5 Years and older
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Epilepsy; Seizure, Sleep
Interventions: NextSense EEG-enabled earbuds; Device
Lead sponsor: NextSense, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Stage IV Breast Cancer
Interventions: Vaccination with Mimotope P10s-PADRE/MONTANIDE ISA 51 VG; Biological
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years and older · Female only
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2019
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Suicide Prevention
Interventions: " Safer Still " Interactive Intervention, Enhanced Usual Care (EUC):; Behavioral · Other
Lead sponsor: Jeff Bridge; Other
Eligibility: 18 Years to 90 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 2
States / cities: Columbus, Ohio

Conditions: Pediatric Obesity
Interventions: ADAPT+, EUC; Behavioral
Lead sponsor: University of South Florida; Other
Eligibility: 8 Years to 12 Years
Enrollment: 95 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Hypertension, Metabolic Syndrome
Interventions: Aliskerin/Valsartan and Rampiril; Drug
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 80 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Overweight and Obesity
Interventions: food-specific go/no-go computerized training, nonfood-specific go/no-go computerized training; Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Duluth, Minnesota

Conditions: Hypertension, Essential (Primary) Hypertension
Interventions: Mindfulness in Motion; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Diabetes
Interventions: Proactive population care (active application of HOAP principles in patients flagged as high risk for hypoglycemia), Usual care, after system-side dissemination of HOAP; Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Pleasanton, California

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Effects of a Combined Transcranial Magnetic Stimulation (TMS) and Cognitive Training in Alzheimer Patients

Intern Health Study 2026

Predicting Patients' Response to Spinal Manipulation

VR Usage in Non-Invasive Surgical Sub-Specialty Procedures

Exercise Programs in Healthy Young Women at Increased Risk of Developing Breast Cancer

Evaluation of Clinical Impact of Non-Invasive Hemodynamic Monitoring to Optimize Perioperative Care

Chiropractic for Hypertension in Patients

Identifying Which Adverse Events Associated With Dry Needling Should be Included For Informed Consent: A Modified e-Delphi Study

Sequential Multiple Assignment Randomized Trial for Bipolar Depression

Effects of Transcranial Electrical Stimulation on Task Performance in Healthy Adults

ME/CFS Brain Fog: Cognitive Rehabilitation Trial

Phase II/III Study Evaluating the Effect of IL-2 on Preservation of the CD4 T-Lymphocytes After Interruption of Antiretroviral Treatment in HIV-Infected Patients With CD4 T-Lymphocyte Count Greater Than 500 Cells/mm3 Who Received Antiretroviral Tx

Study of TUB-040 Given With Standard Ovarian Cancer Drugs in Patients With Fast-growing Ovarian Cancer

Mechanistic Validation of Human Multipolar TES-TI: Amplitude Modulation, Frequency, and Benchmarking

Effects of Exogenous Ketones on Cognitive Function in Older Adults With Prediabetes?

Family Diabetes Prevention Program Pilot Study

Earbud EEG Feasibility Study

Vaccination of High Risk Breast Cancer Patients

Safer Still (Exploratory Project 3)

Adapting Diet and Action for Everyone (ADAPT+)

The Study of Novel Dual Renin Angiotensin Aldosterone System (RAAS) Blockade; Valsartan/Aliskiren in African American Patients With Hypertension and the Metabolic Syndrome

Go/No-Go Intervention for Weight Loss

Evaluating the Effects of a Mindfulness Intervention on Health Outcomes in Individuals With Hypertension

Hypoglycemia Prevention in High-Risk Type 2 Diabetes Patients