Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 4, 2026, 12:13 AM EDT

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Showing 1–2 of 2 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Opioid Dependence, Opioid Withdrawal, Sleep Disturbance
Interventions
Placebo oral capsule, Low Dose Suvorexant, High Dose Suvorexant
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Active, not recruiting Phase 1 Interventional

Targeting Orexin to Treat Nicotine Dependence

NCT03999099
Conditions
Nicotine Dependence
Interventions
Suvorexant 20 mg, Suvorexant 10 mg, Placebo oral tablet
Drug
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Belmont, Massachusetts