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ClinicalTrials.gov public records Last synced Oct 4, 2026, 7:39 AM EDT

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Showing 73–96 of 102 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: High Fat, High Calorie Meal Clear all
Not listed Not applicable Interventional

Can Lifestyle Changes Reverse Early-Stage Alzheimer's Disease

NCT04606420
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Lifestyle medicine
Behavioral
Lead sponsor
Preventive Medicine Research Institute
Other
Eligibility
45 Years to 90 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
4
States / cities
San Diego, California • Sausalito, California • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 15, 2022 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Evaluate Taste and Relative Bioavailability of Two Microsphere Formulations of Crizotinib in Healthy Participants

NCT03978143
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Treatment A, Treatment B, Treatment C, Treatment D, Treatment E, Treatment F, Treatment G, Treatment H
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 55 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 15, 2019 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of High Carbohydrate vs. Low Carbohydrate Diet in Type 2 Diabetes

NCT04416204
View directory record Official record
Conditions
Diabetes Mellitus, Diabetes Mellitus, Type 2
Interventions
glycogen loading, No Glycogen Loading
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
30 Years to 75 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 1, 2024 · Synced Oct 4, 2026, 7:39 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

The Effects of a High Protein Breakfast on Appetite and Sleep in Young Adults

NCT03031132
View directory record Official record
Conditions
Appetite and General Nutritional Disorders
Interventions
HP-Beverage Breakfast, HP-Solid Breakfast, Breakfast Skipping
Behavioral
Lead sponsor
Purdue University
Other
Eligibility
20 Years to 32 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 19, 2017 · Synced Oct 4, 2026, 7:39 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Effects of Red Beetroot Juice on High-Fat Meal-Induced Endothelial Dysfunction and Cardiometabolic Disturbances

NCT02949115
View directory record Official record
Conditions
Overweight, Obesity, Aging, Menopause
Interventions
70 mL red beetroot juice, 70 mL red beetroot juice without nitrate, 70 mL placebo drink plus potassium nitrate, 70 mL placebo drink
Dietary Supplement
Lead sponsor
Colorado State University
Other
Eligibility
40 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 13, 2018 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Four Arm Food Effect Study of Fenofibric Acid Tablets

NCT00960856
View directory record Official record
Conditions
Healthy
Interventions
Fenofibric Acid 105 mg Tablet
Drug
Lead sponsor
Mutual Pharmaceutical Company, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Oct 20, 2009 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Relative Bioavailability and Food Effect Study of CVN424

NCT05635461
View directory record Official record
Conditions
Parkinson's Disease
Interventions
CVN424
Drug
Lead sponsor
Cerevance Beta, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 4, 2026, 7:39 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Stearic Acid and Endothelial Function

NCT07831603
View directory record Official record
Conditions
Healthy Middle-aged Subjects, Obesity & Overweight
Interventions
High Palmitic Acid Diet, Stearic Acid Test Meal, Oleic Acid Test Meal, High Stearic Acid Diet, High Oleic Acid Diet, Palmitic Acid Test Meal
Other
Lead sponsor
Florida State University
Other
Eligibility
40 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Palatability (Energy I Pilot)

NCT01653886
View directory record Official record
Conditions
Energy Density
Interventions
Breakfast (1-2 hours, in the morning), Lunch (1-2 Hours, at midday), Dinner (1-2 hours, in the afternoon)
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 50 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Feb 4, 2016 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Food Effect of VS-6766 in Healthy Adult Subjects

NCT05187169
View directory record Official record
Conditions
Food Effect
Interventions
VS-6766
Drug
Lead sponsor
Verastem, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated May 10, 2022 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Maribavir Food-Effect Study in Healthy Adults Participants

NCT05382104
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Maribavir
Drug
Lead sponsor
Takeda
Industry
Eligibility
19 Years to 55 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Feb 16, 2024 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Compare Bioavailability of AZD5055 Film-coated Tablet With AZD5055 Oral Suspension and to Assess the Effect of Food and an Acid Reducing Agent on Pharmacokinetics (PK) of AZD5055 in Healthy Subjects.

NCT05630677
View directory record Official record
Conditions
Healthy Volunteers
Interventions
AZD5055 solution for infusion, AZD5055 oral suspension, AZD5055 film-coated tablet, Rabeprazole, Delayed-release tablet
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 55 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Brooklyn, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2024 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effect of Food on the Pharmacokinetics of ASTX660 in Healthy Volunteers

NCT04479800
View directory record Official record
Conditions
Healthy Volunteer
Interventions
ASTX660
Drug
Lead sponsor
Astex Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 2, 2024 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Monocyte Priming When Consuming a Western Diet

NCT05348395
View directory record Official record
Conditions
Heart Diseases
Interventions
Experimental diet
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
20 Years to 45 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 6, 2026 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

A Study of TAK-227 in Healthy Adults

NCT05818956
View directory record Official record
Conditions
Healthy Volunteers
Interventions
TAK-227
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 55 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Evaluate BMS-986165 Tablet Formulation Relative to BMS-986165 Capsule Formulation and the Effect of a High-Fat/ High-Calorie Meal and Increased Gastric pH on the BMS-986165 Tablet Formulation

NCT03254784
View directory record Official record
Conditions
Systemic Lupus Erythematosus, Arthritic Psoriasis, Psoriasis, Inflammatory Bowel Diseases
Interventions
BMS-986165 Capsule, BMS-986165 Tablet
Drug
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
18 Years to 50 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Lenexa, Kansas
Source: ClinicalTrials.gov public record
Updated Feb 25, 2020 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Brown Adipose Tissue Activation on Insulin Sensitivity in Humans

NCT01791114
View directory record Official record
Conditions
Insulin Sensitivity, Obesity
Interventions
Cold exposure, Cold exposure plus propranolol, Thermoneutral Conditions, Cold water consumption, Tepid water consumption, Exercise, Meal consumption
Other
Lead sponsor
Rutgers University
Other
Eligibility
18 Years to 75 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 16, 2021 · Synced Oct 4, 2026, 7:39 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional

A Study of Anvumetostat in Participants With Advanced MTAP-null Solid Tumors (MTAPESTRY 101)

NCT05094336
View directory record Official record
Conditions
Advanced MTAP-null Solid Tumors
Interventions
Anvumetostat, Docetaxel, Comparator Anvumetostat Test Tablet
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years to 100 Years
Enrollment
329 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
30
States / cities
Duarte, California • Glendale, California • Oxnard, California + 24 more
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Single Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of BIIB061 in Healthy Adult Volunteers Including Absolute Bioavailability and Food Effect

NCT02071121
View directory record Official record
Conditions
Healthy
Interventions
BIIB061, Placebo, 14C-BIIB061
Drug
Lead sponsor
Biogen
Industry
Eligibility
20 Years to 55 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
2
States / cities
Evansville, Indiana • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 2, 2015 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study in Healthy Male Subjects to Understand How Savolitinib Behaves Inside the Body (Pharmacokinetics) When Administered Alone and in Combination With Famotidine

NCT04179071
View directory record Official record
Conditions
Solid Tumours
Interventions
Savolitinib, Famotidine
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 65 Years · Male only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Epigenetic Effects of a Single Bout of Exercise on Cardiovascular Risk Factors and the Metabolome

NCT05034380
View directory record Official record
Conditions
Obesity, Type 2 Diabetes, Cardiovascular Diseases, Acute Exercise
Interventions
Acute exercise
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 5, 2021 · Synced Oct 4, 2026, 7:39 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Retrospective Chart Review of the 5 & 2 & 2 and 4 & 2 & 1 Plans

NCT02150837
View directory record Official record
Conditions
Obesity
Interventions
5 & 2 & 2 Plan, 4 & 2 & 1 Plan
Other
Lead sponsor
Medifast, Inc.
Industry
Eligibility
18 Years and older
Enrollment
372 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Owings Mills, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 13, 2019 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study Of Glasdegib In Healthy Volunteers To Establish The Bioequivalence Of The Phase 2 Formulation To The ICH Formulation

NCT03130556
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Glasdegib, High Fat, High Calorie Meal, Rabeprazole
Drug · Other
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 55 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 1, 2017 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Not applicable Interventional Results available

Targeting Obesity to Optimize Health in Cardiac Rehab (TOPCARE)

NCT03423238
View directory record Official record
Conditions
Obesity, Weight Loss, CHD - Coronary Heart Disease
Interventions
Exercise, Health Education, Exercise Compliance, Calorie-Restricted Diet, Behavioral Modification, Weight-Loss Compliance, Dietary Counseling
Other · Behavioral · Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
40 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 23, 2021 · Synced Oct 4, 2026, 7:39 AM EDT