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ClinicalTrials.gov public records Last synced Oct 21, 2026, 1:27 AM EDT

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Showing 1–24 of 211 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: High Intensity Interval Exercise Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility of a Train-the-Trainer Delivered Exercise Intervention in Firefighters

NCT05287594
View directory record Official record
Conditions
Firefighter, High Intensity Interval Training
Interventions
Integrated Exercise Program
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 60 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 21, 2026, 1:27 AM EDT
Completed Not applicable Interventional

The Effect of Exercise on Muscle Dysfunction in Cystinosis

NCT04071548
View directory record Official record
Conditions
Cystinosis
Interventions
HIIT Exercise
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 60 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Oct 21, 2026, 1:27 AM EDT
Recruiting Not applicable Interventional

Preliminary Efficacy of Different Exercise Training During Immunotherapy in Patients With Lung Cancer: The ENHANCE Trial

NCT06026111
View directory record Official record
Conditions
Lung Cancer
Interventions
High-Intensity Interval Training (HIIT), Moderate-Intensity Continuous Training (MICT)
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 21, 2026, 1:27 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Exercise Dose and Metformin for Vascular Health in Metabolic Syndrome

NCT03355469
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Metformin, Placebo, Low Intensity Exercise, High Intensity Exercise
Drug · Behavioral
Lead sponsor
Rutgers University
Other
Eligibility
40 Years to 80 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Oct 21, 2026, 1:27 AM EDT
Completed Not applicable Interventional Results available

Relationship of Exercise, Sleep, and Inflammation Markers in People Living With HIV

NCT04946994
View directory record Official record
Conditions
Hiv, Sleep
Interventions
HIIT, CME
Behavioral
Lead sponsor
Christine Horvat Davey
Other
Eligibility
50 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Aurora, Colorado • Cleveland, Ohio • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 21, 2026, 1:27 AM EDT
Recruiting Not applicable Interventional

High-Intensity Exercise to Combat Vascular and Cognitive Dysfunction in Adults With HIV

NCT05965518
View directory record Official record
Conditions
HIV, Arterial Stiffness, Cognitive Dysfunction
Interventions
High-Intensity Interval Training, Continuous Moderate Exercise
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
50 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 21, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Work Rate Adjustments During a High-intensity Interval Training on a Stationary Bike in a Hot and Temperate Environment

NCT05988606
View directory record Official record
Conditions
High-Intensity Interval Training, Heat
Interventions
15 minutes of high-intensity interval training, 43 minutes of high-intensity interval training, Hot environment, Temperate environment
Behavioral · Other
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
18 Years to 39 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 21, 2026, 1:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Guided Episodic Future Thinking to Increase Physical Activity Adherence and Promote Healthy Brain Aging

NCT06123182
View directory record Official record
Conditions
Exercise Training, Aging
Interventions
Episodic Future Thinking, Episodic Recent Thinking, Positive Affective Imagery, Neutral Affective Imagery, HIIT Exercise Intervention
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
45 Years to 65 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 21, 2026, 1:27 AM EDT
Completed Phase 2 Interventional

Effect of Activities and Exercise on Sleep in Elderly Persons With Dementia

NCT00888706
View directory record Official record
Conditions
Dementia, Elderly, Sleep
Interventions
Control Condition, Individualized Social Activities (ISA), Physical Resistance Training and Walking (PRT/walking), Combined ISA/PRT/walking
Behavioral
Lead sponsor
National Institute of Nursing Research (NINR)
NIH
Eligibility
55 Years and older
Enrollment
355 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Apr 28, 2009 · Synced Oct 21, 2026, 1:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of HIIT vs. TRE on Type 2 Diabetes Risk

NCT07215533
View directory record Official record
Conditions
Obesity and Type 2 Diabetes, Metabolic Diseases, High-intensity Interval Training, Time-restricted Eating
Interventions
High-intensity interval training, Time-restricted eating
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
14 Years to 30 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Oct 10, 2025 · Synced Oct 21, 2026, 1:27 AM EDT
Completed Phase 2 Interventional

Fitness After Stroke Trial

NCT05936008
View directory record Official record
Conditions
Stroke, Stroke, Ischemic, Stroke Hemorrhagic
Interventions
Exercise MICT, Exercise HIIT
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
20 Years to 85 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Oct 21, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cardiac Rehab and Cerebral Blood Flow Study

NCT05012878
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Cardiac rehabilitation - high intensity interval training (HIIT), Cardiac rehabilitation - moderate intensity continuous training (MICT), Cardiac rehabilitation - control, Cardiac rehabilitation - observational
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 29, 2025 · Synced Oct 21, 2026, 1:27 AM EDT
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Classroom Break, Cognition, and Fitness in Elementary School Children

NCT06258941
View directory record Official record
Conditions
Healthy Volunteers
Interventions
MF-HIIT, HIIT-only, MF-only, Sedentary activity
Behavioral
Lead sponsor
Purdue University
Other
Eligibility
8 Years to 12 Years
Enrollment
352 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Royal Center, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 21, 2026, 1:27 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Physician-based Decision Support

NCT03443713
View directory record Official record
Conditions
Type 1 Diabetes Mellitus, MDI, CGM, Exercise
Interventions
Dexcom G6 CGM
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 50 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 18, 2020 · Synced Oct 21, 2026, 1:27 AM EDT
Active, not recruiting Phase 1 Interventional

A Study of Exercise and Pharmacologic Intervention on Systemic Inflammation

NCT07058974
View directory record Official record
Conditions
Smokers, Former Smokers
Interventions
lamivudine, rapamycin, Exercise Regimen, Spermidine
Drug · Behavioral · Dietary Supplement
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
60 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 21, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Exercise Preconditioning and Breast Cancer Cardiotoxicity

NCT02842658
View directory record Official record
Conditions
Breast Cancer
Interventions
A high-intensity interval exercise group, An Attention-Control Group
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years to 70 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 24, 2020 · Synced Oct 21, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reversing Muscle Loss With Exercise Training and Daily Consumption of Pomegranate Juice

NCT03258346
View directory record Official record
Conditions
Sarcopenia, Cardiovascular Risk Factor
Interventions
Inertial Load Cycling Training, Pomegranate Juice, Placebo
Other · Dietary Supplement
Lead sponsor
University of Texas at Austin
Other
Eligibility
50 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Feb 20, 2019 · Synced Oct 21, 2026, 1:27 AM EDT
Not yet recruiting Not applicable Interventional

Home-Based High-Intensity Interval Training in Systemic Lupus Erythematosus

NCT07716462
View directory record Official record
Conditions
Systemic Lupus Erthematosus, Fatigue, Exercise Training
Interventions
Personalized Home-Based High-Intensity Interval Training
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 21, 2026, 1:27 AM EDT
Completed Not applicable Interventional

REmotely Monitored, Mobile Health-Supported High Intensity Interval Training After COVID-19 Critical Illness (REMM-HIIT-COVID-19)

NCT04664101
View directory record Official record
Conditions
Covid19, Critical Illness, High Intensity Interval Training, ICU, Intensive Care Units, Fitness Trackers
Interventions
REmotely Monitored, Mhealth (REMM) supported High Intensity Interval Training (HIIT), Comparator
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Durham, North Carolina • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 18, 2024 · Synced Oct 21, 2026, 1:27 AM EDT
Completed Not applicable Interventional Results available

High-Intensity Exercise to Attenuate Limitations and Train Habits in Older Adults With HIV

NCT04550676
View directory record Official record
Conditions
Hiv, Fatigue, Mobility Limitation
Interventions
HIIT (intervention), CME (active control), Coaching, Control text message
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years and older
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Aurora, Colorado • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 21, 2026, 1:27 AM EDT
Completed Not applicable Interventional Results available

Context Aware Data Gathering Study

NCT04154904
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Exercise
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Oct 21, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Exercise Training to Promote Resilience to Chronic Lymphocytic Leukemia

NCT04950452
View directory record Official record
Conditions
Aging, Chronic Lymphocytic Leukemia
Interventions
Exercise Training
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 6, 2021 · Synced Oct 21, 2026, 1:27 AM EDT
Completed Not applicable Interventional

High-intensity Interval Circuit Training in People With Parkinson Disease

NCT06576817
View directory record Official record
Conditions
Parkinson Disease
Interventions
High intensity circuit exercise class - Lower and upper extremity, High intensity circuit exercise class - Lower extremity alone
Other
Lead sponsor
Pacific Northwest University of Health Sciences
Other
Eligibility
Not listed
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Yakima, Washington
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 21, 2026, 1:27 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Acute Effects of Exercise in College Students With ADHD

NCT03666416
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder, Effects of; Exertion, Working Memory, Change in Sustained Attention
Interventions
Sprint Interval Training
Behavioral
Lead sponsor
University of Wyoming
Other
Eligibility
18 Years to 29 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
Laramie, Wyoming
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Oct 21, 2026, 1:27 AM EDT