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ClinicalTrials.gov public records Last synced Oct 18, 2026, 8:23 PM EDT

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Showing 193–216 of 547 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: High Intensity Intervention Clear all
Completed Not applicable Interventional Accepts healthy volunteers

The First 20 Fire Academy Recruits Exercise Training Program

NCT03319394
View directory record Official record
Conditions
Physical Fitness
Interventions
The First Twenty, Comparison
Behavioral
Lead sponsor
Kansas State University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Manhattan, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 24, 2017 · Synced Oct 18, 2026, 8:23 PM EDT
Active, not recruiting Not applicable Interventional

Adaptive Symptom Self-Management Immunotherapy Study

NCT05715255
View directory record Official record
Conditions
Breast Cancer, Colon Cancer, Lung Cancer, Skin Cancer, Rectum Cancer
Interventions
Automated Telephone Symptom Management (ATMS) and Telephone Interpersonal Counseling (TIP-C), Active control comparator
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
Phoenix, Arizona • Tucson, Arizona • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 18, 2026, 8:23 PM EDT
Recruiting Phase 2 Interventional

Window of Opportunity in Preserving Laryngeal Function Trial

NCT07423078
View directory record Official record
Conditions
Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M), Locally Advanced Laryngeal Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma
Interventions
Toripalimab, Carboplatin, Cisplatin, Paclitaxel, Radiation Therapy
Drug · Radiation
Lead sponsor
Matthew Spector
Other
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 18, 2026, 8:23 PM EDT
Recruiting Not applicable Interventional

Lifestyle Intervention of Food and Exercise for Lymphoma Survivors

NCT05839210
View directory record Official record
Conditions
Non Hodgkin Lymphoma, Hodgkin Lymphoma
Interventions
LIFE-L Mediterranean Diet, LIFE-L Home-Based Exercise Program, Supportive Materials
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Oct 18, 2026, 8:23 PM EDT
Completed Not applicable Interventional

RIC (Remote Ischemic Conditioning) in Older Individuals

NCT06476288
View directory record Official record
Conditions
Old Age, Mobility Limitation, Debility
Interventions
Low-intensity resistance exercise training, High-Dose Remote ischemic conditioning (RIC), Low-Dose Remote ischemic conditioning (RIC)
Other
Lead sponsor
Duke University
Other
Eligibility
65 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 18, 2026, 8:23 PM EDT
Completed Not applicable Interventional

Cardiovascular Effects of High Intensity Interval Training in Individuals With Paraplegia

NCT04378218
View directory record Official record
Conditions
Paraplegia, Spinal, Spinal Cord Trauma
Interventions
High Intensity Interval Training (HIIT)
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 20, 2021 · Synced Oct 18, 2026, 8:23 PM EDT
Completed Not applicable Interventional

Mild Cognitive Impairment, Buddy Supported Exercise/ My Buddy Study

NCT01561820
View directory record Official record
Conditions
Mild Cognitive Impairment, Cognitive Disorders
Interventions
5-month aerobic exercise intervention
Behavioral
Lead sponsor
Wake Forest University
Other
Eligibility
60 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Oct 18, 2026, 8:23 PM EDT
Completed Not applicable Interventional

Feasibility of HIIT in Older Adults with HIV and Hypertension

NCT06888596
View directory record Official record
Conditions
HIV, Hypertension, Exercise
Interventions
Exercise
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
50 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 21, 2025 · Synced Oct 18, 2026, 8:23 PM EDT
Recruiting Not applicable Interventional

EMPOWER: Effects of Weight Loss and Exercise Post-stroke

NCT05901675
View directory record Official record
Conditions
Obesity, Stroke
Interventions
Lifestyle Management Program, Post-stroke Optimization of Walking using Explosive Resistance
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
35 Years to 85 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 18, 2026, 8:23 PM EDT
Not yet recruiting Phase 3 Interventional

Multiparametric Ultrasound for the Diagnosis of Clinically Significant Prostate Cancer

NCT06024772
View directory record Official record
Conditions
Prostate Carcinoma
Interventions
ultiparametric Magnetic Resonance Imaging, Perflutren lipid microsphere, Transrectal Ultrasound, Biopsy of Prostate
Procedure · Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older · Male only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 18, 2026, 8:23 PM EDT
Not yet recruiting Not applicable Interventional

Optimal Dosing of High-Intensity Locomotor Training for Step Attainment and Locomotor Outcomes in Stroke Patients Undergoing Acute Inpatient Rehabilitation

NCT06637839
View directory record Official record
Conditions
Stroke
Interventions
Moderate-Intensity Locomotor Training Program, High-Intensity Locomotor Training Program, High-Step Count Locomotor Training Program
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 95 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 18, 2026, 8:23 PM EDT
Terminated Phase 3 Interventional

Ultrasound in Treating Patients With Recurrent Stage I or Stage II Prostate Cancer

NCT00005075
View directory record Official record
Conditions
Prostate Cancer
Interventions
high-intensity focused ultrasound ablation
Procedure
Lead sponsor
EDAP Technomed
Industry
Eligibility
50 Years and older · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1999
U.S. locations
2
States / cities
San Francisco, California • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 6, 2013 · Synced Oct 18, 2026, 8:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sympathetic Activation in Obesity

NCT04946552
View directory record Official record
Conditions
Obesity, Healthy
Interventions
PET Scan, Mixed Meal Test, Muscle sympathetic nerve activity (MSNA), Oral Glucose Tolerance Test, Body Composition, Percent Body Fat & Percent Body Water (Tanita scale), CT Scan, Body Composition, Percent Body Fat & Percent Body Water (DXA Scan)
Diagnostic Test · Dietary Supplement · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 45 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 16, 2024 · Synced Oct 18, 2026, 8:23 PM EDT
Completed Early Phase 1 Interventional

Expedited Laser Interstitial Thermal Therapy + Chemoradiation For Newly Diagnosed High Grade Gliomas

NCT02970448
View directory record Official record
Conditions
High Grade Glioma
Interventions
LITT, Radiation therapy, Temozolomide
Procedure · Radiation · Drug
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 18, 2026, 8:23 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers

Vitamin D Status, Disease Specific and Quality of Life Outcomes in Patients With Cutaneous Lupus

NCT01498406
View directory record Official record
Conditions
Cutaneous Lupus Erythematosus
Interventions
vitamin D
Dietary Supplement
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 20, 2013 · Synced Oct 18, 2026, 8:23 PM EDT
Completed No phase listed Observational

Lactate Monitoring in Traumatic Long Bone Fractures Requiring Emergent Surgical Intervention

NCT05611398
View directory record Official record
Conditions
Lactate Blood Increase, Trauma Blunt, Trauma, Secondary, Injury Traumatic
Interventions
Orthopedic Surgery
Procedure
Lead sponsor
Arrowhead Regional Medical Center
Other
Eligibility
Not listed
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Colton, California
Source: ClinicalTrials.gov public record
Updated Nov 10, 2022 · Synced Oct 18, 2026, 8:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dietary Intervention and Varying Physical Activity in Seniors

NCT01893684
View directory record Official record
Conditions
Obesity
Interventions
Exercise, Higher Protein Diet, Conventional Carbohydrate Diet
Behavioral
Lead sponsor
University of Georgia
Other
Eligibility
65 Years to 80 Years · Female only
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 7, 2017 · Synced Oct 18, 2026, 8:23 PM EDT
Completed Not applicable Interventional

Enhanced Medical Rehabilitation for Spinal Cord Injury

NCT03952416
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Enhanced Medical Rehabilitation (EMR)
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 5, 2024 · Synced Oct 18, 2026, 8:23 PM EDT
Active, not recruiting Not applicable Interventional

CET- REM (Correlating ECT Response to EEG Markers)

NCT04451135
View directory record Official record
Conditions
ECT, Treatment Resistant Depression
Interventions
Electroencephalographic (EEG), Quick Inventory of Depressive Symptomatology-Self Report (QIDS-SR16), Ictal Electroencephalographic (EEG) Measurements, Post-Ictal Electroencephalographic (EEG) Suppression Measurements
Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 31, 2025 · Synced Oct 18, 2026, 8:23 PM EDT
Completed Phase 4 Interventional Results available

Pre-exposure Prophylaxis (PrEP) Adherence Enhancement Guided by iTAB and Drug Levels for Women

NCT02584140
View directory record Official record
Conditions
HIV Prevention
Interventions
Text Messaging, Adherence Counseling, Daily Oral PrEP
Behavioral · Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Female only
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
5
States / cities
Los Angeles, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 8, 2021 · Synced Oct 18, 2026, 8:23 PM EDT
Completed Not applicable Interventional

Community Supported Risk Reduction for Syringe Exchange Participants

NCT02654366
View directory record Official record
Conditions
Substance Use Disorders, Risk Reduction
Interventions
Risk Reduction Group
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 70 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 20, 2020 · Synced Oct 18, 2026, 8:23 PM EDT
Not listed Not applicable Interventional

Transcutaneous Spinal Stimulation for Lower Limb Spasticity in Spinal Cord Injury

NCT05457205
View directory record Official record
Conditions
Spinal Cord Injuries, Spasticity, Muscle
Interventions
Electrical neuromodulation
Other
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Apr 12, 2024 · Synced Oct 18, 2026, 8:23 PM EDT
Recruiting Phase 1 Interventional

CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia

NCT04375631
View directory record Official record
Conditions
Recurrent Acute Myeloid Leukemia, Recurrent Chronic Myelomonocytic Leukemia, Recurrent Myelodysplastic Syndrome, Refractory Acute Myeloid Leukemia, Refractory Chronic Myelomonocytic Leukemia, Refractory Mixed Phenotype Acute Leukemia, Refractory Myelodysplastic Syndrome, Refractory Acute Leukemia of Ambiguous Lineage, Refractory Acute Undifferentiated Leukemia
Interventions
Cladribine, Cyclophosphamide, Cyclosporine, Cytarabine, Filgrastim, Hematopoietic Cell Transplantation, Mitoxantrone, Mycophenolate Mofetil, Mycophenolate Sodium, Total-Body Irradiation, Idarubicin, Fludarabine, Multigated Acquisition Scan, Echocardiography Test, X-Ray Imaging, Bone Marrow Biopsy, Bone Marrow Aspiration, Biospecimen Collection
Drug · Biological · Procedure + 1 more
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 18, 2026, 8:23 PM EDT
Recruiting Not applicable Interventional

The REACTplusNMES Trial: A Double-blinded RCT

NCT06127602
View directory record Official record
Conditions
Stroke, Ischemic, Stroke Hemorrhagic, Stroke, Cerebrovascular
Interventions
Reactive balance training with Neuromuscular Electrical Stimulation, Reactive balance training without Neuromuscular Electrical Stimulation
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 90 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 18, 2026, 8:23 PM EDT