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ClinicalTrials.gov public records Last synced Oct 19, 2026, 6:18 AM EDT

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Showing 49–72 of 232 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: High fiber Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Assessing the Dose Response of a Lead Fiber Snack Prototype

NCT04729816
View directory record Official record
Conditions
Microbiota, Gastrointestinal Microbiome
Interventions
Controlled, high fat/low fiber diet background diet, sequentially supplemented with an escalating dose of a fiber-blend snack food.
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 60 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 27, 2024 · Synced Oct 19, 2026, 6:18 AM EDT
Recruiting Not applicable Interventional

High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial

NCT06298734
View directory record Official record
Conditions
Melanoma (Skin), Skin Cancer, Advanced Melanoma
Interventions
Exercise Program, Diet Program
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 19, 2026, 6:18 AM EDT
Completed Not applicable Interventional

High Fat Diet II on Weight Loss

NCT00525850
View directory record Official record
Conditions
Obesity
Interventions
high fat diet, low saturated fat diet
Other
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Aug 2, 2011 · Synced Oct 19, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Hi-maize Resistant Starch on Insulin Sensitivity

NCT01058135
View directory record Official record
Conditions
Insulin Resistance
Interventions
Hi-maize starch (Low dose), Hi-maize starch (High-dose), Control (starch)
Other
Lead sponsor
Ingredion Incorporated
Industry
Eligibility
18 Years to 69 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Glen Ellyn, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 21, 2016 · Synced Oct 19, 2026, 6:18 AM EDT
Not listed Not applicable Interventional

The Effect of a High Fiber Diet and High-Intensity Interval Exercise in Patients With HFpEF

NCT05236413
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
High Intensity Interval Exercise, Dietary Approaches to Stop Hypertension (DASH) Diet, Exercise + DASH Diet
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
40 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Oct 19, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigation of How Morning Nutrition Influences Cognitive Performance

NCT03169283
View directory record Official record
Conditions
Cognitive Performance
Interventions
Cereal with B glucan, Cereal without B glucan
Other
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
18 Years to 44 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Oct 19, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Thermic & Lipemic Properties of Dietary Carbohydrates

NCT01354574
View directory record Official record
Conditions
Exogenous Obesity, Dietary Modification
Interventions
High Glycemic Index meals, Low Glycemic Index meals
Other
Lead sponsor
USDA, Western Human Nutrition Research Center
Federal
Eligibility
18 Years to 48 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2005
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Jul 13, 2011 · Synced Oct 19, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ultra-processed Food Consumption, Gut Microbiota, and Glucose Homeostasis

NCT05358171
View directory record Official record
Conditions
Insulin Sensitivity, 24-hour Glucose Control
Interventions
HIgh UPF controlled diet, No UPF controlled diet
Other
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
40 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Oct 19, 2026, 6:18 AM EDT
Completed Phase 2 Interventional Results available

Phase II Study of Short-Term Cultured Anti-Tumor Autologous Lymphocytes After Lymphocyte-Depleting Chemotherapy in Metastatic Melanoma

NCT00513604
View directory record Official record
Conditions
Melanoma, Malignant Melanoma, Melanoma, Experimental, Experimental Melanomas
Interventions
aldesleukin, therapeutic autologous lymphocytes, Cyclophosphamide, Fludarabine phosphate, Total body irradiation
Biological · Drug · Radiation
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 3, 2013 · Synced Oct 19, 2026, 6:18 AM EDT
Completed Not applicable Interventional Results available

Blueberries, Inflammation, Motivation, and Physical Activity

NCT05735587
View directory record Official record
Conditions
Depressive Symptoms
Interventions
Freeze-dried Blueberry Powder, Placebo Powder
Other
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
65 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Roslindale, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Oct 19, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Randomized, Crossover Study to Assess the Effects of Dietary Fiber-containing Bars on Glucose and Insulin Responses

NCT03796286
View directory record Official record
Conditions
Blood Glucose, Insulin Sensitivity, Dietary Fiber
Interventions
Medium-fiber bar, High-fiber bar, Control bar (0 g fiber)
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 65 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
2
States / cities
Boca Raton, Florida • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 24, 2019 · Synced Oct 19, 2026, 6:18 AM EDT
Not listed Not applicable Interventional

Effect of Preoperative Diet on Perioperative Gut Microbiome

NCT05027763
View directory record Official record
Conditions
Surgical Site Infection
Interventions
high-fiber/low fat, fermented
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 24, 2025 · Synced Oct 19, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resistant Starch Insulin Sensitivity Trial

NCT01027325
View directory record Official record
Conditions
Healthy, Cardiovascular Disease, Atherogenic Dyslipidemia, Insulin Resistance
Interventions
Dietary Intervention
Other
Lead sponsor
UCSF Benioff Children's Hospital Oakland
Other
Eligibility
20 Years and older
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
2
States / cities
Berkeley, California • Oakland, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2013 · Synced Oct 19, 2026, 6:18 AM EDT
Completed Not applicable Interventional Results available

Brain Energy for Amyloid Transformation in Alzheimer's Disease Study

NCT03472664
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment
Interventions
low carbohydrate/high fat diet, low fat/high carbohydrate diet
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
55 Years to 85 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 19, 2026, 6:18 AM EDT
Terminated Phase 2 Interventional Results available

Photodynamic Therapy (PDT) For Recurrent High Grade Gliomas

NCT01966809
View directory record Official record
Conditions
Brain Tumor, Recurrent
Interventions
Photofrin photodynamic therapy.
Drug
Lead sponsor
Harry T Whelan, MD
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 20, 2019 · Synced Oct 19, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Young Adult Eating Habits

NCT05550818
View directory record Official record
Conditions
Eating Behavior, Eating Habit
Interventions
High Ultra Processed Food Diet, No Ultra Processed Food Diet
Other
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years to 25 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
2
States / cities
Blacksburg, Virginia • Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 19, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Food, Adolescence, Mood, and Exercise

NCT02015377
View directory record Official record
Conditions
Overweight, Obesity
Interventions
High sugar versus low sugar meals
Other
Lead sponsor
University of Southern California
Other
Eligibility
14 Years to 17 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 31, 2017 · Synced Oct 19, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ButyraGen™, Short Chain Fatty Acids and Gut Microbiome

NCT05601635
View directory record Official record
Conditions
Healthy
Interventions
ButyraGen™
Dietary Supplement
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Industry
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 25, 2023 · Synced Oct 19, 2026, 6:18 AM EDT
Not listed No phase listed Observational

HR-EGG in Medically Refractory Gastroparesis

NCT05789511
View directory record Official record
Conditions
Gastroparesis, Lung Transplant; Complications
Interventions
High Resolution Electrogastography
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Houston, Texas • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 31, 2023 · Synced Oct 19, 2026, 6:18 AM EDT
Not yet recruiting Not applicable Interventional

Reset: Enhancing Weight Loss in a Digital Intervention

NCT07032571
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss, Health Behavior, Lifestyle Intervention
Interventions
Core Behavioral Weight Loss Intervention, Limit Red Zone Foods, Limit Eating Window, Increase Protein, Increase Fiber Intake
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 19, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

How Accurately Does the Diopsys Visual Evoked Potential (VEP) Vision Testing System Detect Glaucoma?

NCT02622178
View directory record Official record
Conditions
Glaucoma Diagnosis
Interventions
Optical Coherence Tomography, Visual evoked potential
Diagnostic Test
Lead sponsor
Wills Eye
Other
Eligibility
18 Years to 90 Years
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 15, 2018 · Synced Oct 19, 2026, 6:18 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Dietary Fiber Effects on the Microbiome and Satiety

NCT04611217
View directory record Official record
Conditions
Dietary Fiber
Interventions
Dietary fiber: 10-25g, Dietary fiber: 5g
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
20 Years to 55 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 22, 2025 · Synced Oct 19, 2026, 6:18 AM EDT
Recruiting Phase 1Phase 2 Interventional

Manipulation of the Gut Microbiome by a Standardized Preoperative Diet to Prevent Colorectal Cancer Recurrence and Metastasis Following Surgery

NCT06349590
View directory record Official record
Conditions
Colorectal Cancer
Interventions
High-fiber/low-fat meals
Dietary Supplement
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 19, 2026, 6:18 AM EDT
Completed Not applicable Interventional Results available

High- Fiber/ Low-fat Diet for Prevention of Recurrent Clostridioides Difficile Infection in Oncology

NCT04940468
View directory record Official record
Conditions
Leukemia, Lymphocytic, Acute, Leukemia, Myeloid, Acute, Lymphoma, Clostridium Difficile Infection, Solid Cancers
Interventions
Diet Intervention
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
9 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 19, 2026, 6:18 AM EDT