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Conditions: Smell Dysfunction, Olfactory Disorder, Long COVID
Interventions: Trigeminal Nerve Stimulation (TNS), Active Smell Training (ST), Placebo Smell Training (PBO); Device · Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 65 Years
Enrollment: 145 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Chronic Low-back Pain
Interventions: Algorithmically informed randomization (taking into account phenotypes), Physical Therapy (PT) and Exercise, Cognitive-Behavioral Therapy for Pain (PRISM-CBT), mHealth Acupressure Self-Management:, Duloxetine; Device · Behavioral · Drug
Lead sponsor: University of Michigan; Other
Eligibility: 25 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Prostate Cancer
Interventions: 3-D Conformal Radiation Therapy, Intensity Modulated Radiation Therapy, Casodex, Zoladex , Lupron; Radiation · Drug
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older · Male only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Fairway, Kansas

Conditions: Prostate Cancer
Interventions: high-intensity focused ultrasound ablation; Procedure
Lead sponsor: Focus Surgery; Industry
Eligibility: 40 Years to 80 Years · Male only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2006
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Carcinoma, Squamous Cell of Head and Neck
Interventions: AZD1775, Cisplatin, Intensity Modulated Radiotherapy Treatments; Drug · Radiation
Lead sponsor: UNC Lineberger Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Glucose Metabolism Disorders, Lipid Metabolism Disorders, Metabolic Diseases
Interventions: Aerobic Exercise; Behavioral
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years to 100 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Aphasia, Stroke, Aphasia Following Cerebral Infarction, Aphasia, Acquired
Interventions: Transcranial Magnetic Stimulation (TMS), Speech-Language Therapy (SLT); Device · Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 40 Years to 85 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Muscle Damage
Interventions: Far Infrared Fabric, Spandex; Other
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 35 Years
Enrollment: 84 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Refractory and/or Relapsed Metastatic Solid Tumors
Interventions: Cyclophosphamide, Fludarabine, low dose total body irradiation, Melphalan, Tacrolimus; Drug · Radiation
Lead sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; Other
Eligibility: 1 Year to 50 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2030
U.S. locations: 3
States / cities: Baltimore, Maryland • The Bronx, New York • Valhalla, New York

Conditions: HPV, Oropharynx Cancer, HPV-Related Carcinoma, HPV-Related Malignancy, HPV Positive Oropharyngeal Squamous Cell Carcinoma
Interventions: HPV ctDNA Assay, MRI Studies, EORTC QLQ H&N 35 and C30, MDADI-HN, COST-FACIT, Intensity-Modulated Radiation Therapy (Arm A), Chemoradiation (Arm B); Diagnostic Test · Behavioral · Radiation + 1 more
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 8
States / cities: Miami, Florida • Basking Ridge, New Jersey • Middletown, New Jersey + 5 more

Conditions: Mild Traumatic Brain Injury
Interventions: Sub-symptomatic Adaptable Exercise Treatment (SAET), Stretching Control Group (SCG); Behavioral
Lead sponsor: United States Naval Medical Center, San Diego; Federal
Eligibility: 18 Years to 55 Years
Enrollment: 140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Camp Pendleton, California

Conditions: Cerebral Palsy, Dyskinetic, Secondary Dystonia
Interventions: Focused Ultrasound Pallidotomy; Device
Lead sponsor: Children's National Research Institute; Other
Eligibility: 8 Years to 22 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Rheumatoid Arthritis
Interventions: HIIT; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 60 Years to 80 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2015
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Stress Urinary Incontinence, Urge Incontinence, Urge and Stress, Overactive Bladder
Interventions: BTL EMSELLA Active treatment, BTL EMSELLA Sham Treatment; Device
Lead sponsor: Boston Urogynecology Associates; Other
Eligibility: 18 Years to 100 Years · Female only
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Conditions: Cerebral Palsy
Interventions: Prone and Upright Locomotor Training; Behavioral
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: Up to 6 Weeks
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Chronic Pain, Pain, Musculoskeletal, Opioid Use, Physical Therapy
Interventions: Mindfulness based practice, Control/Standard Physical Therapy; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 75 Years
Enrollment: 93 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 2
States / cities: Gainesville, Florida • Salt Lake City, Utah

Conditions: Substance Use Disorder, Mental Health Disorder, Homelessness
Interventions: Employing Peer Outreach and Whole Health in Recovery (EMPOWER); Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 278 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Melanoma
Interventions: Electronic Health Record Review, Internet-Based Intervention, Patient Navigation, Survey Administration; Other · Behavioral
Lead sponsor: OHSU Knight Cancer Institute; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Myeloproliferative Disorders, Kidney Cancer, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases
Interventions: anti-thymocyte globulin, busulfan, cyclophosphamide, fludarabine phosphate, methotrexate, tacrolimus, nonmyeloablative allogeneic HSCT; Biological · Drug · Procedure
Lead sponsor: Northside Hospital, Inc.; Other
Eligibility: Up to 75 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Breast Cysts, Breast Tumors
Interventions: X-ray and ultrasound imaging scanning, Photoacoustic imaging scans for breast cancer screening; Procedure
Lead sponsor: University of Michigan; Other
Eligibility: 30 Years to 80 Years · Female only
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2020
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Intellectual Disability, Developmental Disability, Axis I Diagnosis, Mental Illness, Covid19, Coronavirus
Interventions: Generic Best Practices, Tailored Best Practices; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 415 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Lymphoma, Leukemia, Myelodysplastic Syndrome
Interventions: Fludarabine, Busulfan, Cyclophosphamide, Mycophenolate Mofetil, Tacrolimus; Drug
Lead sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; Other
Eligibility: 6 Months to 75 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Exercise Performance
Interventions: Hyperbaric chamber, Ambient pressure; Other
Lead sponsor: Intermountain Health Care, Inc.; Other
Eligibility: 18 Years to 40 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Murray, Utah

Conditions: Healthy
Interventions: Respiratory Maximus Training Device, No Respiratory Training Device; Device
Lead sponsor: University of South Carolina; Other
Eligibility: 18 Years to 35 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Columbia, South Carolina

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Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT for Long COVID)

Algorithm-informed Decision-making to Advance Pain Treatment

Clinical Trial Comparing 3-D RT vs. IMRT in Post- Prostatectomy Prostate Cancer Patients

Ultrasound in Treating Patients With Prostate Cancer Confined to the Prostate

Dose-escalating AZD1775 + Concurrent Radiation + Cisplatin for Intermediate/High Risk HNSCC

Effect of Age on Glucose and Lipid Metabolism

Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia

Effect of Compression Garments on Exercise Performance Following Acute High Intensity Exercise

Reduced Intensity Haploidentical BMT for High Risk Solid Tumors

A Study on Using Cell-Free Tumor DNA (ctDNA) Testing to Decide When to StartRoutine Treatment in People With Human Papilloma Virus (HPV)- Associated Oropharynx Cancer (OPC)

Treatment Optimization of Brain-injured Warfighters

Focused Ultrasound Pallidotomy for Dyskinetic Cerebral Palsy in Pediatric and Young Adult Subjects

High Intensity Interval Training and Rheumatoid Arthritis

High Intensity Focused Electromagnetic Field Device for Urinary Incontinence

Locomotor Learning in Infants at High Risk for Cerebral Palsy

Physical Therapy Integrated With Mindfulness for Patients With Chronic Pain and Opioid Treatment

Employing Peer Outreach and Whole Health in Recovery for Homeless-Experienced Veterans

Feasibility of an Enhanced Symptom Monitoring and Expedited Subspecialty Care Referral Intervention to Improve Side Effect Management for Patients With Melanoma Receiving an Immune Checkpoint Inhibitor

Early Administration of ATG Followed by Cyclophosphamide, Busulfan and Fludarabine Before a Donor Stem Cell Transplant in Patients With Hematological Cancer

Simulated Screening Study for Breast Imaging

Best Practices to Prevent COVID-19 Illness in Staff and People With Serious Mental Illness and Developmental Disabilities in Congregate Living Settings

Reduced-intensity, Related-donor Bone Marrow Transplantation Followed by High-dose Cyclophosphamide for Hematologic Cancers

Effects of High-Intensity Interval Training (HIT) While in a Hyperoxic-Hyperbaric Environment on Exercise Performance

Training Adaptations With and Without Ventilatory Training Device