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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: High intensity interval training Clear all
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Classroom Break, Cognition, and Fitness in Elementary School Children

NCT06258941
View directory record Official record
Conditions
Healthy Volunteers
Interventions
MF-HIIT, HIIT-only, MF-only, Sedentary activity
Behavioral
Lead sponsor
Purdue University
Other
Eligibility
8 Years to 12 Years
Enrollment
352 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Royal Center, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 23, 2026, 8:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Metabolic Flexibility as a Biomarker of Adaptation to Diet and Exercise Challenges

NCT01987388
View directory record Official record
Conditions
Healthy Volunteers
Interventions
High Intensity Exercise, Low Intensity Exercise, High Carbohydrate Beverage, High Fat Beverage
Other
Lead sponsor
USDA Beltsville Human Nutrition Research Center
Federal
Eligibility
22 Years to 35 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Beltsville, Maryland
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Sep 23, 2026, 8:54 PM EDT
Completed Not applicable Interventional

Improving Age-Related Cognitive Decline With Exercise in Hypertensive Older Adults

NCT05043454
View directory record Official record
Conditions
Hypertension
Interventions
High Intensity Interval Training (HIIT) Exercise
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
55 Years to 75 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 23, 2026, 8:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Ethnicity on Changes in VO2max and Cardiac Output in Response to Short-Term High Intensity Interval Training

NCT04449016
View directory record Official record
Conditions
Improved VO2max and Cardiac Output in Response to Training
Interventions
High intensity interval training
Other
Lead sponsor
California State University, San Marcos
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
San Marcos, California
Source: ClinicalTrials.gov public record
Updated Jun 25, 2020 · Synced Sep 23, 2026, 8:54 PM EDT
Completed Phase 2 Interventional

Family-Focused Therapy for Youth With Early-Onset Bipolar or Psychotic Disorders

NCT02097563
View directory record Official record
Conditions
Mood Disorders, Psychotic Disorders
Interventions
High Intensity Training, Low Intensity Training
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
13 Years to 25 Years
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
3
States / cities
Culver City, California • Granada Hills, California • Torrance, California
Source: ClinicalTrials.gov public record
Updated Mar 24, 2020 · Synced Sep 23, 2026, 8:54 PM EDT
Recruiting Not applicable Interventional

Exercise for Tumor Suppressive Impact in Men With Prostate Cancer at High-Risk of Progression on Active Surveillance: The REMOVE Trial

NCT05918263
View directory record Official record
Conditions
Prostate Cancer, Prostatic Neoplasms
Interventions
High-Intensity Interval Training Exercise Program
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older · Male only
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
4
States / cities
Boston, Massachusetts • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Sep 23, 2026, 8:54 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Cardiorespiratory Fitness and Acute High-Intensity Exercise Effects on Brain and Cognitive Function in Older Adults

NCT07727577
View directory record Official record
Conditions
Healthy Aging, Cognitive Benefits, Cardio Respiratory Fitness, Brain Activity
Interventions
High-Intensity Interval Training
Behavioral
Lead sponsor
Colby-Sawyer College
Other
Eligibility
55 Years to 79 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
New London, New Hampshire
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 23, 2026, 8:54 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Guided Episodic Future Thinking to Increase Physical Activity Adherence and Promote Healthy Brain Aging

NCT06123182
View directory record Official record
Conditions
Exercise Training, Aging
Interventions
Episodic Future Thinking, Episodic Recent Thinking, Positive Affective Imagery, Neutral Affective Imagery, HIIT Exercise Intervention
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
45 Years to 65 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 23, 2026, 8:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interval Training, Inflammation and Immune Function

NCT02441205
View directory record Official record
Conditions
Aging, Disease
Interventions
High Intensity Interval training
Behavioral
Lead sponsor
Duke University
Other
Eligibility
65 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 8, 2017 · Synced Sep 23, 2026, 8:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Aerobic Interval Training on Cardiovascular Function in Type 2 Diabetes

NCT01883258
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
High intensity aerobic interval training, Continuous moderate intensity exercise
Other
Lead sponsor
University of Florida
Other
Eligibility
30 Years to 79 Years
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 5, 2019 · Synced Sep 23, 2026, 8:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sprint to Fitness: Effect of Outcome Expectations on Responses to Interval Exercise Training

NCT03162978
View directory record Official record
Conditions
Overweight, Obesity
Interventions
HIIT + POE, HIIT only
Other
Lead sponsor
USDA Grand Forks Human Nutrition Research Center
Federal
Eligibility
18 Years to 40 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Sep 23, 2026, 8:54 PM EDT
Completed Not applicable Interventional Results available

Evaluation of The Postprandial Impact of Automated Priming Bolus for Full Closed Loop Insulin Delivery

NCT05528770
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
FCL+BPS, FCL
Device
Lead sponsor
Marc Breton
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 7, 2025 · Synced Sep 23, 2026, 8:54 PM EDT
Completed Not applicable Interventional Results available

Moderate-Intensity Exercise Versus High-Intensity Interval Training to Recover Walking Post-Stroke

NCT03760016
View directory record Official record
Conditions
Stroke
Interventions
Moderate-Intensity Aerobic Training, High-Intensity Interval Training
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
40 Years to 80 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
3
States / cities
Newark, Delaware • Kansas City, Kansas • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Sep 23, 2026, 8:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Body Weight-Based Interval Training in Sedentary Overweight and Obese Adults

NCT03524521
View directory record Official record
Conditions
Body Weight Changes, Overweight and Obesity, Physical Activity
Interventions
Interval Training, Standard of Care
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 10, 2021 · Synced Sep 23, 2026, 8:54 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Impact of Aerobic Exercise on Pain Modulation in Healthy Adults

NCT07083219
View directory record Official record
Conditions
Healthy Adult
Interventions
Aerobic High Intensity Interval Training
Behavioral
Lead sponsor
University of Texas, El Paso
Other
Eligibility
18 Years to 50 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Sep 23, 2026, 8:54 PM EDT
Completed Not applicable Interventional Results available

A Research Program Targeting Pre- and Peri-transplant Optimization Program (R-PPOP)

NCT03823651
View directory record Official record
Conditions
Hematologic Malignancy
Interventions
Interval training, Psychiatric consult, Nutrition/diet evaluation, Referral to Social Worker
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Sep 23, 2026, 8:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CASH- Children Active to Stay Healthy

NCT01821313
View directory record Official record
Conditions
Childhood Obesity, Inflammation
Interventions
Moderate exercise, High Intensity Interval Exercise
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
13 Years to 17 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 23, 2015 · Synced Sep 23, 2026, 8:54 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Dual-benefits of Aerobic and Resistance Training

NCT03978572
View directory record Official record
Conditions
Sarcopenia, Aging, Disability Physical
Interventions
Resistance Training, Moderate-Intensity Continuous Cycling, High-Intensity Interval Cycling
Behavioral
Lead sponsor
Ohio University
Other
Eligibility
60 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 15, 2020 · Synced Sep 23, 2026, 8:54 PM EDT
Completed Not applicable Interventional

Effects of High-intensity Gait Training on Fatigue, Gait, and Neuroplasticity in People With Multiple Sclerosis

NCT06264336
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
treadmill training
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
21 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 23, 2026, 8:54 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Exercise Training Intensity and Nitrate Supplementation in Post-Menopausal Females

NCT06480695
View directory record Official record
Conditions
Menopause
Interventions
Nitrate-Rich Beetroot Juice, High Intensity Exercise, Moderate Intensity Exercise, Nitrate-Depleted Placebo Beetroot Juice
Dietary Supplement · Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
45 Years to 75 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 23, 2026, 8:54 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Nicotinamide Mononucleotide Supplementation for Exercise Tolerance Improvement in Healthy Older Adults

NCT07144527
View directory record Official record
Conditions
Aging, Frailty, Exercise Tolerance, Healthy Male and Female Subjects
Interventions
NMN, betaine, low-dose hydrogen peroxide (EGA), Nicotinamide Mononucleotide (NMN), Placebo
Dietary Supplement
Lead sponsor
Scott Silveira
Other
Eligibility
60 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Beverly Hills, California
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Sep 23, 2026, 8:54 PM EDT
Completed Not applicable Interventional

Rehabilitation Strategies to Improve Outcomes For Patients With a Lower Extremity Fracture

NCT05274022
View directory record Official record
Conditions
Femoral Fracture, Tibial Fractures
Interventions
Standard of Care Physical Therapy Program, Speed Walking Intervention
Other
Lead sponsor
Brian W. Noehren
Other
Eligibility
18 Years to 50 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Lexington, Kentucky • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Sep 23, 2026, 8:54 PM EDT
Completed Not applicable Interventional

Exercise Study Testing Enhanced Energetics of Mitochondria Video Integrated Delivery of Activity Training in CKD

NCT02923063
View directory record Official record
Conditions
Moderate-severe Chronic Kidney Disease Not Treated With Dialysis, Diabetic Kidney Disease, HgbA1c Less Than 8.5
Interventions
Combined Aerobic and Resistance Exercise via videoconferencing
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
30 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Sep 23, 2026, 8:54 PM EDT
Active, not recruiting Not applicable Interventional

Improving Cognitive Function Through High-intensity Interval Training in Breast Cancer Patients Undergoing Chemotherapy

NCT04724499
View directory record Official record
Conditions
Breast Cancer, Chemotherapy Effect, Exercise Therapy, Cognitive Change
Interventions
High-Intensity Intervals Training, Attention Control
Behavioral · Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 23, 2026, 8:54 PM EDT