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ClinicalTrials.gov public records Last synced Oct 8, 2026, 10:13 AM EDT

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Showing 25–48 of 79 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: High sodium diet and low sodium diet Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Dietary Salt in Postural Tachycardia Syndrome

NCT01547117
View directory record Official record
Conditions
Postural Orthostatic Tachycardia Syndrome
Interventions
Blood Volume, Total Blood Volume, Exercise Capacity Test - Bicycle, Posture Study
Radiation · Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 50 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 22, 2022 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

The Role of COX-2 Inhibition in Salt Sensitivity of Blood Pressure

NCT00624559
View directory record Official record
Conditions
Hypertension
Interventions
celecoxib (Celebrex), Placebo
Drug · Other
Lead sponsor
University of Delaware
Other
Eligibility
22 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Jan 6, 2012 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dietary Approaches for Cardiometabolic Health

NCT03527290
View directory record Official record
Conditions
Obesity, Abdominal, Dyslipidemias, Insulin Resistance, Blood Pressure, Weight Loss
Interventions
Time Restricted Eating, Standard Cardiometabolic Health Diet
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
22 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Mar 29, 2021 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Phase 4 Interventional Results available

Effect of High and Low Sodium Diets on Blood Pressure in Hypertensive Patients Treated With Aliskiren

NCT00441064
View directory record Official record
Conditions
Hypertension
Interventions
Aliskiren
Drug
Lead sponsor
Novartis
Industry
Eligibility
18 Years to 60 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
19
States / cities
Orangevale, California • Brooklyn Center, Minnesota • Butte, Montana + 16 more
Source: ClinicalTrials.gov public record
Updated Mar 25, 2011 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Not applicable Interventional

Modifying Dietary Behavior in Adolescents With Elevated Blood Pressure

NCT00585832
View directory record Official record
Conditions
Hypertension, Pre-Hypertension
Interventions
DASH-4-Teens, Routine Care
Behavioral · Other
Lead sponsor
University of Cincinnati
Other
Eligibility
11 Years to 18 Years
Enrollment
207 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 14, 2022 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Rehydration Following Exercise-Induced Dehydration

NCT01974986
View directory record Official record
Conditions
Dehydration Related to Exercise
Interventions
Water with flavoring and non-nutritive sweetener., High-Na low-CHO beverage, Low-Na high-CHO beverage
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 2, 2016 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Not applicable Interventional Results available

Effects of the Dietary Approaches to Stop Hypertension(DASH) Sodium-restricted Diet in Diastolic Heart Failure

NCT00939640
View directory record Official record
Conditions
Diastolic Heart Failure, Hypertensive Heart Disease
Interventions
DASH/sodium-restricted diet (SRD)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
50 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 15, 2019 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Increased Free Fatty Acids on Leptin Function

NCT01520454
View directory record Official record
Conditions
Obesity, Leptin Resistance
Interventions
Saline, Intralipid, Water, oral fat, Heparin
Drug · Dietary Supplement
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 11, 2018 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Not applicable Interventional Results available

MOBILE Intervention in College Students With Elevated Blood Pressure

NCT05956925
View directory record Official record
Conditions
Hypertension
Interventions
Intervention group was asked to take their BP daily and rate their motivation level and communicate with the research assistant. Their level will trigger the appropriate behavioral change SMS prompt.
Behavioral
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 29 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Oct 8, 2026, 10:13 AM EDT
Active, not recruiting Not applicable Interventional

Renal Metabolism in Salt-sensitive Human Blood Pressure

NCT05369416
View directory record Official record
Conditions
Hypertension
Interventions
Low sodium diet, high sodium diet
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
30 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Oct 8, 2026, 10:13 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Dietary Oxalate and Immune Cell Function

NCT03877276
View directory record Official record
Conditions
Kidney Stone
Interventions
Breakfast, Spinach smoothie, Kale smoothie, Blended smoothie, V spinach smoothie, Sodium oxalate drink
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 70 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 8, 2026, 10:13 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Potassium Supplementation Study

NCT05887622
View directory record Official record
Conditions
Cardiovascular Health, Cardiovascular Risk Factor
Interventions
Potassium chloride supplement, Placebo
Dietary Supplement
Lead sponsor
University of Delaware
Other
Eligibility
18 Years to 45 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 8, 2026, 10:13 AM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Liver Glycogen and Hypoglycemia in Humans

NCT03241706
View directory record Official record
Conditions
Hypoglycemia; Iatrogenic
Interventions
Low Fructose, Saline, Somatostatin, Insulin, Glucagon, Dextrose solution, High Fructose
Drug
Lead sponsor
Jason Winnick
Other
Eligibility
21 Years to 40 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2028
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 25, 2025 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Phase 4 Interventional

Effects of Glucosamine and Chondroitin Supplementation in Women With Knee Osteoarthritis Participating in an Exercise and Weight Loss Program

NCT01271218
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Diet, Exercise
Other
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
College Station, Texas
Source: ClinicalTrials.gov public record
Updated Jan 6, 2011 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Not applicable Interventional

Facts-Up-Front Versus Traffic-Light Food Labels

NCT01626729
View directory record Official record
Conditions
Food Labeling
Interventions
Traffic Light+, Facts Up Front+, No label control group
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
703 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 25, 2012 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Phase 1Phase 2 Interventional

Dietary Intervention With the Modified Atkins Diet in Stroke Rehabilitation

NCT01820663
View directory record Official record
Conditions
Stroke, Ischemic Stroke
Interventions
Modified Atkins Diet, Control diet
Other
Lead sponsor
Burke Rehabilitation Hospital
Other
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Feb 24, 2016 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Dietary Sodium's Effect on Urinary Sodium and Dopamine Excretion in Patients With Postural Tachycardia Syndrome

NCT01563107
View directory record Official record
Conditions
Postural Orthostatic Tachycardia Syndrome
Interventions
Plasma Volume, Exercise Capacity Test - Bicycle, Posture Study
Radiation · Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Return of First-phase Insulin Secretion in Type 2 Diabetes is Associated With Depletion of Pancreas Lipid

NCT03430310
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Low Glycemic Diet, Control Diet
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
35 Years to 65 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 24, 2024 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Not applicable Interventional

Smartstep Smartphone PAD

NCT03479255
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Smartphone-enabled structured exercise therapy (SE-SET), Standard exercise therapy
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 89 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 13, 2025 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Stroke Health and Risk Education (SHARE)

NCT01378780
View directory record Official record
Conditions
Stroke, Hypertension
Interventions
Educational intervention for diet and physical activity, Educational message on skin cancer awareness
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
760 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Corpus Christi, Texas
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Hemodynamic Effects of Aliskiren Compared to Captopril on the Kidney in Healthy Volunteers on a Low- and High- Sodium Diet

NCT00518765
View directory record Official record
Conditions
Hypertension
Interventions
Aliskiren, Aliskiren plus placebo
Drug
Lead sponsor
Novartis
Industry
Eligibility
18 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2005
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 6, 2010 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of Sodium and Fructose on Blood Pressure and Inflammation

NCT04994418
View directory record Official record
Conditions
Blood Pressure, Inflammation
Interventions
Recommended sodium and low fructose diet, High sodium and low fructose diet, High sodium and high fructose diet
Dietary Supplement
Lead sponsor
University of Delaware
Other
Eligibility
18 Years to 45 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Dec 6, 2024 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Not applicable Interventional Results available

Dietary Salt in Rheumatoid Arthritis

NCT03649178
View directory record Official record
Conditions
Rheumatoid Arthritis
Interventions
salt
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Not applicable Interventional

When the Kidney Reacts to Nutritional Changes

NCT04142138
View directory record Official record
Conditions
Prehypertension
Interventions
DASH
Other
Lead sponsor
Rockefeller University
Other
Eligibility
18 Years to 60 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 5, 2021 · Synced Oct 8, 2026, 10:13 AM EDT