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ClinicalTrials.gov public records Last synced Sep 8, 2026, 2:48 AM EDT

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Showing 1–24 of 55 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: High-Intensity Interval Cycling Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

A SMART Trial of Adaptive Exercises to Optimize Aerobic-Fitness Responses

NCT05877196
View directory record Official record
Conditions
Mild Cognitive Impairment, Alzheimer Disease, Cognitive Impairment, Cognitive Decline, Memory Loss, Memory Impairment
Interventions
Moderate Intensity Continuous Training (MICT), Chair-based Stretch, High-Intensity Interval Training (HIIT), Combined Aerobic Resistance Exercise (CARE)
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
65 Years and older
Enrollment
216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 8, 2026, 2:48 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

High-Intensity Interval Training and Regulatory T Cells

NCT04774484
View directory record Official record
Conditions
End Stage Renal Disease
Interventions
High Intensity Interval Training
Other
Lead sponsor
Francesc Marti
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 13, 2023 · Synced Sep 8, 2026, 2:48 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

High-Intensity Interval Training for Older Adults

NCT05542758
View directory record Official record
Conditions
Age-Related Sarcopenia
Interventions
Total Body HIIT Program
Other
Lead sponsor
Creighton University
Other
Eligibility
65 Years to 95 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jul 15, 2024 · Synced Sep 8, 2026, 2:48 AM EDT
Recruiting Not applicable Interventional

Changes in Movement, Fitness, and Quality of Life in People With Parkinson's Disease After Different Exercise Programs

NCT07221266
View directory record Official record
Conditions
Parkinson Disease (PD)
Interventions
Guided Cycling, Non-Contact Boxing, Traditional Physical Therapy Program (Standard of Care)
Behavioral
Lead sponsor
University of Texas, El Paso
Other
Eligibility
50 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 8, 2026, 2:48 AM EDT
Active, not recruiting Not applicable Interventional

Improving Cognitive Function Through High-intensity Interval Training in Breast Cancer Patients Undergoing Chemotherapy

NCT04724499
View directory record Official record
Conditions
Breast Cancer, Chemotherapy Effect, Exercise Therapy, Cognitive Change
Interventions
High-Intensity Intervals Training, Attention Control
Behavioral · Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 8, 2026, 2:48 AM EDT
Withdrawn Not applicable Interventional

High Intensity Interval Training in Heart Failure

NCT03032081
View directory record Official record
Conditions
Heart Failure, Physical Activity
Interventions
High intensity exercise, Moderate intensity exercise
Other
Lead sponsor
Georgia State University
Other
Eligibility
40 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 22, 2017 · Synced Sep 8, 2026, 2:48 AM EDT
Completed Not applicable Interventional Results available

Feasibility of HIIT in Spinal Cord Injury

NCT03152110
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Diseases
Interventions
HIIT
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Sep 8, 2026, 2:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

High Intensity Interval Versus Continuous Moderate Intensity Training: Maximizing the Benefits of Exercise in Overweight Adolescents

NCT01935323
View directory record Official record
Conditions
Metabolism, Physical Fitness
Interventions
High Intensity Interval Training, Moderate Intensity Training
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
17 Years to 22 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 11, 2016 · Synced Sep 8, 2026, 2:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Aerobic Interval Training on Cardiovascular Function in Type 2 Diabetes

NCT01883258
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
High intensity aerobic interval training, Continuous moderate intensity exercise
Other
Lead sponsor
University of Florida
Other
Eligibility
30 Years to 79 Years
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 5, 2019 · Synced Sep 8, 2026, 2:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of a High-Protein Diet and/or High-Intensity Training on Metabolic Syndrome

NCT01622634
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Sprint Interval Exercise, Higher PRO Diet, Higher CARB Diet
Behavioral · Other
Lead sponsor
University of Georgia
Other
Eligibility
30 Years to 65 Years · Female only
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 24, 2015 · Synced Sep 8, 2026, 2:48 AM EDT
Completed Not applicable Interventional

Combining HIIT and n-3 PUFA to Reduce Inflammation and Improve Metabolic Health

NCT05295719
View directory record Official record
Conditions
Obesity, Inflammation, Human Microbiome, Insulin Resistance, Dyslipidemias
Interventions
Omega-3 polyunsaturated fatty acid, High-Intensity Interval Training, Safflower oil, Low-intensity training
Dietary Supplement · Behavioral
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years to 65 Years
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Sep 8, 2026, 2:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

High-Intensity Interval Training in a Community Gym

NCT06976060
View directory record Official record
Conditions
Age-related Strength Loss
Interventions
High-Intensity Interval Training
Behavioral
Lead sponsor
Creighton University
Other
Eligibility
50 Years to 95 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Sep 8, 2026, 2:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

High Intensity Cycling Before SCUBA Diving Reduces Post-decompression Microparticle Production and Neutrophil Activation

NCT02064361
View directory record Official record
Conditions
Decompression Sickness, SCUBA Diving
Interventions
High intensity exercise
Other
Lead sponsor
University of Split
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 16, 2014 · Synced Sep 8, 2026, 2:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility of a Train-the-Trainer Delivered Exercise Intervention in Firefighters

NCT05287594
View directory record Official record
Conditions
Firefighter, High Intensity Interval Training
Interventions
Integrated Exercise Program
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 60 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Sep 8, 2026, 2:48 AM EDT
Completed Not applicable Interventional

The Effects of Two Exercise Interventions on Breast Cancer Patients Undergoing Cardiotoxic Chemotherapies

NCT05786014
View directory record Official record
Conditions
Breast Cancer, Cardiotoxicity, Cardiovascular Diseases
Interventions
High Intensity Interval Exercise, Moderate Intensity Walking
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Sep 8, 2026, 2:48 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Dual-benefits of Aerobic and Resistance Training

NCT03978572
View directory record Official record
Conditions
Sarcopenia, Aging, Disability Physical
Interventions
Resistance Training, Moderate-Intensity Continuous Cycling, High-Intensity Interval Cycling
Behavioral
Lead sponsor
Ohio University
Other
Eligibility
60 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 15, 2020 · Synced Sep 8, 2026, 2:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Aerobic Interval Training on Cardiovascular Function in Aging

NCT01883271
View directory record Official record
Conditions
Aging
Interventions
High intensity aerobic interval training, Continuous moderate intensity exercise
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 79 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 24, 2019 · Synced Sep 8, 2026, 2:48 AM EDT
Recruiting Not applicable Interventional

Preliminary Efficacy of Different Exercise Training During Immunotherapy in Patients With Lung Cancer: The ENHANCE Trial

NCT06026111
View directory record Official record
Conditions
Lung Cancer
Interventions
High-Intensity Interval Training (HIIT), Moderate-Intensity Continuous Training (MICT)
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 8, 2026, 2:48 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Identification of Novel Skeletal Muscle-derived Factors That Promote Lipid Oxidation (Columbus)

NCT01911091
View directory record Official record
Conditions
Obesity, Disorder of Lipid Storage and Metabolism, Lipid Metabolism Disorders, Metabolic Disorder
Interventions
Exercise
Behavioral
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
18 Years to 40 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2026
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 8, 2026, 2:48 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Heat Therapy and Muscle Function Study

NCT04733287
View directory record Official record
Conditions
Exercise Intolerance, Aging, Heat Therapy, High Intensity Interval Training
Interventions
High Intensity Interval Training of the Knee Extensors, Muscle Heat Therapy, Muscle Disuse, Sham Heat Therapy
Other
Lead sponsor
Brigham Young University
Other
Eligibility
18 Years to 95 Years
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Provo, Utah
Source: ClinicalTrials.gov public record
Updated Feb 1, 2021 · Synced Sep 8, 2026, 2:48 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Multidimensional Predictive Modeling to Understand Mechanisms of Exercise Response Heterogeneity in Older Adults (M3AX)

NCT06507189
View directory record Official record
Conditions
Aging, Aging Well
Interventions
Combined endurance and resistance training
Other
Lead sponsor
Florida Institute for Human and Machine Cognition
Other
Eligibility
60 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Pensacola, Florida • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 8, 2026, 2:48 AM EDT
Terminated Not applicable Interventional

INTERVAL: Ipilimumab and Nivolumab Combination Therapy: A Study of a Supervised or Semi-Supervised Exercise InteRVention or Usual Care With Functional Capacity and Quality of Life Evaluations in Subjects With Advanced or Metastatic RenAL Cell Carcinoma

NCT03692338
View directory record Official record
Conditions
Metastatic Renal Cell Carcinoma
Interventions
Exercise
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Sep 8, 2026, 2:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise Induced Plasma Volume Expansion Lowers Cardiovascular Strain

NCT05800808
View directory record Official record
Conditions
Cardiac Output, Stroke Volume
Interventions
High Intensity Intervals, Moderate Exercise
Procedure
Lead sponsor
California Baptist University
Other
Eligibility
18 Years to 38 Years · Male only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Riverside, California
Source: ClinicalTrials.gov public record
Updated Apr 5, 2023 · Synced Sep 8, 2026, 2:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reversing Muscle Loss With Exercise Training and Daily Consumption of Pomegranate Juice

NCT03258346
View directory record Official record
Conditions
Sarcopenia, Cardiovascular Risk Factor
Interventions
Inertial Load Cycling Training, Pomegranate Juice, Placebo
Other · Dietary Supplement
Lead sponsor
University of Texas at Austin
Other
Eligibility
50 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Feb 19, 2019 · Synced Sep 8, 2026, 2:48 AM EDT