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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: High-intensity functional training Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Cardiac Rehab and Cerebral Blood Flow Study

NCT05012878
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Cardiac rehabilitation - high intensity interval training (HIIT), Cardiac rehabilitation - moderate intensity continuous training (MICT), Cardiac rehabilitation - control, Cardiac rehabilitation - observational
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Sep 21, 2026, 2:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mobility Exercises for Gait (MEG Neuroplasticity Project)

NCT03555708
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Physical Therapy
Other
Lead sponsor
University of Nebraska
Other
Eligibility
9 Years to 18 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 4, 2024 · Synced Sep 21, 2026, 2:39 AM EDT
Recruiting Not applicable Interventional

C.A.P.A.B.L.E. (CrossFit® and Physical Activity: A Better Life Experience)

NCT03750981
View directory record Official record
Conditions
Cancer Survivors
Interventions
12 week pilot intervention study.
Behavioral
Lead sponsor
Barbara Ann Karmanos Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Sep 21, 2026, 2:39 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Improving Core Strength in the Warfighter With a Novel Device

NCT06797830
View directory record Official record
Conditions
Core Strengthening, Posture, Low Back Pain
Interventions
AllCore
Device
Lead sponsor
David Moss
Federal
Eligibility
18 Years to 50 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Nellis Air Force Base, Nevada
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Sep 21, 2026, 2:39 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Cardiorespiratory Fitness and Acute High-Intensity Exercise Effects on Brain and Cognitive Function in Older Adults

NCT07727577
View directory record Official record
Conditions
Healthy Aging, Cognitive Benefits, Cardio Respiratory Fitness, Brain Activity
Interventions
High-Intensity Interval Training
Behavioral
Lead sponsor
Colby-Sawyer College
Other
Eligibility
55 Years to 79 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
New London, New Hampshire
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 21, 2026, 2:39 AM EDT
Recruiting Not applicable Interventional

Moderate Versus High Volume Light-Moderate Intensity Exercise for People With Moderate Parkinson's Disease

NCT06088355
View directory record Official record
Conditions
Parkinson Disease, Movement Disorders, Neurodegeneration
Interventions
HV-PDAE: High Volume Partnered Dance Aerobic Exercise, MV-PDAE: Moderate Volume Partnered Dance Aerobic Exercise, MV-WALK: Moderate Volume Walking, HV-WALK: High Volume Walking
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 21, 2026, 2:39 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Objective Assessment of Technical Skills in Cardiothoracic Surgery

NCT01433029
View directory record Official record
Conditions
Other Surgical Procedures
Interventions
Surgical Video Assessments, Video Recording of CAB
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
21 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
6
States / cities
Dallas, Texas • Houston, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 29, 2017 · Synced Sep 21, 2026, 2:39 AM EDT
Active, not recruiting Not applicable Interventional

Mediterranean-DASH Intervention for Neurodegenerative Delay and High-Intensity Interval Training in Adults With Hypertension

NCT07130539
View directory record Official record
Conditions
Hypertension (HTN), Obesity &Amp; Overweight, Sedentary
Interventions
MIND HIIT
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 74 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 18, 2025 · Synced Sep 21, 2026, 2:39 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Impact of Aerobic Exercise on Pain Modulation in Healthy Adults

NCT07083219
View directory record Official record
Conditions
Healthy Adult
Interventions
Aerobic High Intensity Interval Training
Behavioral
Lead sponsor
University of Texas, El Paso
Other
Eligibility
18 Years to 50 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Sep 21, 2026, 2:39 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A SMART Trial of Adaptive Exercises to Optimize Aerobic-Fitness Responses

NCT05877196
View directory record Official record
Conditions
Mild Cognitive Impairment, Alzheimer Disease, Cognitive Impairment, Cognitive Decline, Memory Loss, Memory Impairment
Interventions
Moderate Intensity Continuous Training (MICT), Chair-based Stretch, High-Intensity Interval Training (HIIT), Combined Aerobic Resistance Exercise (CARE)
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
65 Years and older
Enrollment
216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 21, 2026, 2:39 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Daily Upgrade Trial

NCT07792603
View directory record Official record
Conditions
Healthy Women
Interventions
Essential Amino Acid+, Non-Calorie Placebo, High intensity Interval Training, No Exercise
Dietary Supplement · Behavioral · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
25 Years to 45 Years · Female only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 21, 2026, 2:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise-Induced Epigenetic Modifications in Obese Aging Women

NCT01977885
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
High Protein Diet, Exercise
Behavioral
Lead sponsor
University of Georgia
Other
Eligibility
50 Years to 64 Years · Female only
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 24, 2015 · Synced Sep 21, 2026, 2:39 AM EDT
Completed Not applicable Interventional

Walking Balance Training Post-Stroke

NCT06090604
View directory record Official record
Conditions
Stroke
Interventions
High intensity gait training in a balance challenging Movement amplification environment
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 85 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 21, 2026, 2:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

High Intensity Functional Training for Individuals With Neurologic Diagnoses and Their Care Partners

NCT05951985
View directory record Official record
Conditions
Neurologic Disorder, Parkinson Disease, Spinal Cord Injuries, Spina Bifida, Stroke, Poliomyelitis, Multiple Sclerosis, Brain Injuries
Interventions
HIFT
Behavioral
Lead sponsor
Arkansas Colleges of Health Education
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Fort Smith, Arkansas
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Sep 21, 2026, 2:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cadence Modulation to Improve Well-Being, Kinematics and Aerobic Performance in Cyclists

NCT03482726
View directory record Official record
Conditions
Healthy
Interventions
Cycling Cadence Modulation
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 89 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 25, 2019 · Synced Sep 21, 2026, 2:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Acetaminophen and Impaired Musculoskeletal Adaptations to Exercise Training

NCT01083901
View directory record Official record
Conditions
Sarcopenia, Osteoporosis, Aging
Interventions
Resistance training
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years and older · Male only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 23, 2013 · Synced Sep 21, 2026, 2:39 AM EDT
Recruiting Not applicable Interventional

Feasibility of High Intensity Interval Training in Survivors of Childhood, Adolescent, and Young Adult Hodgkin Lymphoma

NCT07222345
View directory record Official record
Conditions
Hodgkin Lymphoma
Interventions
High Intensity Interval Training (HIIT)
Behavioral
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
10 Years to 25 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 21, 2026, 2:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fuel Utilization, Diet Composition, and Exercise in African American Women

NCT04293367
View directory record Official record
Conditions
Obesity, Diabetes, Insulin Resistance
Interventions
High Intensity Interval Training (HIIT)
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
20 Years to 40 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 2, 2020 · Synced Sep 21, 2026, 2:39 AM EDT
Completed Not applicable Interventional

High Intensity Resistance Training + Creatine in Perimenopause

NCT07027800
View directory record Official record
Conditions
Perimenopause
Interventions
Creatine Monohydrate, Placebo
Dietary Supplement
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
38 Years to 60 Years · Female only
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Sep 21, 2026, 2:39 AM EDT
Terminated Not applicable Interventional

TSA Exercise Prehabilitation in Older Adults

NCT03212300
View directory record Official record
Conditions
Postoperative Delirium and Delayed Functional Recovery
Interventions
Aerobic Exercise Training (AET)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
55 Years to 75 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2020 · Synced Sep 21, 2026, 2:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise, Cognitive Function and Neuroplasticity in Healthy Adults

NCT02994134
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
Moderate intensity exercise., High intensity exercise.
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 70 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 7, 2021 · Synced Sep 21, 2026, 2:39 AM EDT
Recruiting Not applicable Interventional

High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial

NCT06298734
View directory record Official record
Conditions
Melanoma (Skin), Skin Cancer, Advanced Melanoma
Interventions
Exercise Program, Diet Program
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 21, 2026, 2:39 AM EDT
Completed Not applicable Interventional

REmotely Monitored, Mobile Health-Supported High Intensity Interval Training After COVID-19 Critical Illness (REMM-HIIT-COVID-19)

NCT04664101
View directory record Official record
Conditions
Covid19, Critical Illness, High Intensity Interval Training, ICU, Intensive Care Units, Fitness Trackers
Interventions
REmotely Monitored, Mhealth (REMM) supported High Intensity Interval Training (HIIT), Comparator
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Durham, North Carolina • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 17, 2024 · Synced Sep 21, 2026, 2:39 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Acute Effect of Exercise on Vascular Function

NCT02408614
View directory record Official record
Conditions
Aging
Interventions
Slow-paced walking, Moderate-paced walking, Interval Training, Treadmill
Other · Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 79 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 24, 2019 · Synced Sep 21, 2026, 2:39 AM EDT