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ClinicalTrials.gov public records Last synced Oct 2, 2026, 10:47 AM EDT

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Showing 73–96 of 100 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: High-intensity interval training (HIIT) exercise Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Precision High-Intensity Training Through Epigenetics (PHITE)

NCT03380923
View directory record Official record
Conditions
Healthy
Interventions
Moderate Intensity, High Intensity
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 27 Years
Enrollment
239 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 7, 2021 · Synced Oct 2, 2026, 10:47 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A SMART Trial of Adaptive Exercises to Optimize Aerobic-Fitness Responses

NCT05877196
View directory record Official record
Conditions
Mild Cognitive Impairment, Alzheimer Disease, Cognitive Impairment, Cognitive Decline, Memory Loss, Memory Impairment
Interventions
Moderate Intensity Continuous Training (MICT), Chair-based Stretch, High-Intensity Interval Training (HIIT), Combined Aerobic Resistance Exercise (CARE)
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
65 Years and older
Enrollment
216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 2, 2026, 10:47 AM EDT
Completed Phase 2 Interventional

Fitness After Stroke Trial

NCT05936008
View directory record Official record
Conditions
Stroke, Stroke, Ischemic, Stroke Hemorrhagic
Interventions
Exercise MICT, Exercise HIIT
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
20 Years to 85 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Oct 2, 2026, 10:47 AM EDT
Not yet recruiting Not applicable Interventional

Home-Based High-Intensity Interval Training in Systemic Lupus Erythematosus

NCT07716462
View directory record Official record
Conditions
Systemic Lupus Erthematosus, Fatigue, Exercise Training
Interventions
Personalized Home-Based High-Intensity Interval Training
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 2, 2026, 10:47 AM EDT
Completed Not applicable Interventional

Improving Age-Related Cognitive Decline With Exercise in Hypertensive Older Adults

NCT05043454
View directory record Official record
Conditions
Hypertension
Interventions
High Intensity Interval Training (HIIT) Exercise
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
55 Years to 75 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 2, 2026, 10:47 AM EDT
Recruiting Not applicable Interventional

Preliminary Efficacy of Different Exercise Training During Immunotherapy in Patients With Lung Cancer: The ENHANCE Trial

NCT06026111
View directory record Official record
Conditions
Lung Cancer
Interventions
High-Intensity Interval Training (HIIT), Moderate-Intensity Continuous Training (MICT)
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 2, 2026, 10:47 AM EDT
Active, not recruiting Not applicable Interventional

Impact of Exercise Intensity on Cardiac Health in Young Adult Survivors of Childhood Cancer: The PULSE Trial

NCT07442578
View directory record Official record
Conditions
Childhood Cancer Survivors, Cardiotoxicity, Cardiovascular Diseases, Anthracycline-induced Cardiotoxicity
Interventions
HIIT Exercise Program, MICT Exercise Program
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years to 39 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 2, 2026, 10:47 AM EDT
Completed Not applicable Interventional

HIIT Following Breast Cancer Chemotherapy

NCT05913713
View directory record Official record
Conditions
Breast Cancer
Interventions
12-week Intervention Period, 12-week Observation Period
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 2, 2026, 10:47 AM EDT
Completed Not applicable Interventional

Feasibility of HIIT in Older Adults with HIV and Hypertension

NCT06888596
View directory record Official record
Conditions
HIV, Hypertension, Exercise
Interventions
Exercise
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
50 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 21, 2025 · Synced Oct 2, 2026, 10:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sprint to Fitness: Effect of Outcome Expectations on Responses to Interval Exercise Training

NCT03162978
View directory record Official record
Conditions
Overweight, Obesity
Interventions
HIIT + POE, HIIT only
Other
Lead sponsor
USDA Grand Forks Human Nutrition Research Center
Federal
Eligibility
18 Years to 40 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated Apr 11, 2025 · Synced Oct 2, 2026, 10:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Ethnicity on Changes in VO2max and Cardiac Output in Response to Short-Term High Intensity Interval Training

NCT04449016
View directory record Official record
Conditions
Improved VO2max and Cardiac Output in Response to Training
Interventions
High intensity interval training
Other
Lead sponsor
California State University, San Marcos
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
San Marcos, California
Source: ClinicalTrials.gov public record
Updated Jun 26, 2020 · Synced Oct 2, 2026, 10:47 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Heat Therapy and Muscle Function Study

NCT04733287
View directory record Official record
Conditions
Exercise Intolerance, Aging, Heat Therapy, High Intensity Interval Training
Interventions
High Intensity Interval Training of the Knee Extensors, Muscle Heat Therapy, Muscle Disuse, Sham Heat Therapy
Other
Lead sponsor
Brigham Young University
Other
Eligibility
18 Years to 95 Years
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Provo, Utah
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Oct 2, 2026, 10:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fuel Utilization, Diet Composition, and Exercise in African American Women

NCT04293367
View directory record Official record
Conditions
Obesity, Diabetes, Insulin Resistance
Interventions
High Intensity Interval Training (HIIT)
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
20 Years to 40 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 3, 2020 · Synced Oct 2, 2026, 10:47 AM EDT
Not listed Not applicable Interventional

The Effect of a High Fiber Diet and High-Intensity Interval Exercise in Patients With HFpEF

NCT05236413
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
High Intensity Interval Exercise, Dietary Approaches to Stop Hypertension (DASH) Diet, Exercise + DASH Diet
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
40 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Oct 2, 2026, 10:47 AM EDT
Recruiting Not applicable Interventional

Determinants of Cardiorespiratory Fitness and Effects of HIIT in Patients With ANOCA Obstructive Coronary Artery Disease(ANOCA)

NCT07182955
View directory record Official record
Conditions
MINOCA, Shortness of Breath, Atherosclerotic Heart Disease of Native Coronary Artery
Interventions
EXERCISE TRAINING WITH OR WITHOUT MEDICATION
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 19, 2025 · Synced Oct 2, 2026, 10:47 AM EDT
Completed Not applicable Interventional

Cardiovascular Effects of High-Intensity Interval Training (HIIT)

NCT03602170
View directory record Official record
Conditions
Healthy Sedentary Adults With BP <140/90
Interventions
High-Intensity Interval Training, Moderate-Intensity Continuous Training
Behavioral
Lead sponsor
University of Delaware
Other
Eligibility
20 Years to 44 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Apr 26, 2019 · Synced Oct 2, 2026, 10:47 AM EDT
Not yet recruiting Not applicable Interventional

Exercise-induced Steroid Changes in Active Surveillance for Prostate Cancer

NCT07518888
View directory record Official record
Conditions
Prostate Cancer
Interventions
High-Intensity Interval Training (HIIT) Exercise
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 80 Years · Male only
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 2, 2026, 10:47 AM EDT
Completed Not applicable Interventional Results available

High-Intensity Interval Training to Improve Symptoms of Deployment-Related Respiratory Disease

NCT05849168
View directory record Official record
Conditions
Occupational Exposure
Interventions
Exercise training
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Oct 2, 2026, 10:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Two Exercise Programs on Obese Patients

NCT03980860
View directory record Official record
Conditions
Obesity, Hypertension
Interventions
Exercise Type
Other
Lead sponsor
Rowan University
Other
Eligibility
18 Years to 89 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Stratford, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 25, 2019 · Synced Oct 2, 2026, 10:47 AM EDT
Completed Not applicable Interventional

Cardiovascular Effects of High Intensity Interval Training in Individuals With Paraplegia

NCT04378218
View directory record Official record
Conditions
Paraplegia, Spinal, Spinal Cord Trauma
Interventions
High Intensity Interval Training (HIIT)
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 20, 2021 · Synced Oct 2, 2026, 10:47 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of High-Intensity Exercise to Attenuate Cognitive Function Limitations and Train Exercise Habits in Older People Living With HIV

NCT06013579
View directory record Official record
Conditions
HIV Infections, Cognitive Impairment
Interventions
Phase 1 Gym Exercise HIIT, Phase 1 Gym Exercise CME, Phase 2 Home Exercise Coaching Text Messages, Phase 2 Home Exercise Control Text Messages
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
50 Years to 80 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
3
States / cities
Birmingham, Alabama • Aurora, Colorado • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Oct 2, 2026, 10:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

High-Intensity Exercise in Older Adults

NCT06199661
View directory record Official record
Conditions
Functional Fitness, Cognitive Abilities
Interventions
APEX
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
50 Years to 80 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 10, 2024 · Synced Oct 2, 2026, 10:47 AM EDT
Active, not recruiting Not applicable Interventional

A Study to Compare the Effectiveness of Different High-intensity Interval Training Programs in Cardiac Rehabilitation

NCT04555512
View directory record Official record
Conditions
Cardiac Rehabilitation
Interventions
Progressive High Intensity Interval Training (PRO-HIIT), Constant High Intensity Interval Training (CON-HIIT)
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Oct 2, 2026, 10:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Comparison of High-intensity Interval Training Protocols on Health and Fitness

NCT03093441
View directory record Official record
Conditions
Healthy
Interventions
Multimodal High-Intensity Interval Training Intervention
Other
Lead sponsor
Oakland University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Rochester, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 13, 2019 · Synced Oct 2, 2026, 10:47 AM EDT