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ClinicalTrials.gov public records Last synced Nov 1, 2026, 4:48 PM EST

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Showing 1–24 of 41 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: High-sodium intake Clear all
Completed Not applicable Interventional

Prepared Meals to Prime and Perpetuate Reduced Dietary Sodium Intake in Hemodialysis

NCT03990311
View directory record Official record
Conditions
Hypertension in Dialysis Patients, Fluid Overload in Dialysis Patients
Interventions
Sodium Restricted Meals, Control
Other
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 18, 2023 · Synced Nov 1, 2026, 4:48 PM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Young Adult Eating Habits

NCT05550818
View directory record Official record
Conditions
Eating Behavior, Eating Habit
Interventions
High Ultra Processed Food Diet, No Ultra Processed Food Diet
Other
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years to 25 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
2
States / cities
Blacksburg, Virginia • Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Nov 1, 2026, 4:48 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Dietary Approaches for Cardiometabolic Health

NCT03527290
View directory record Official record
Conditions
Obesity, Abdominal, Dyslipidemias, Insulin Resistance, Blood Pressure, Weight Loss
Interventions
Time Restricted Eating, Standard Cardiometabolic Health Diet
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
22 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Mar 29, 2021 · Synced Nov 1, 2026, 4:48 PM EST
Completed Not applicable Interventional Results available

MOBILE Intervention in College Students With Elevated Blood Pressure

NCT05956925
View directory record Official record
Conditions
Hypertension
Interventions
Intervention group was asked to take their BP daily and rate their motivation level and communicate with the research assistant. Their level will trigger the appropriate behavioral change SMS prompt.
Behavioral
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 29 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Nov 1, 2026, 4:48 PM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Dietary Phosphate Excess on Exercise Capacity and Visceral Adiposity

NCT05147909
View directory record Official record
Conditions
Physical Inactivity, Phosphate Overload, Visceral Obesity
Interventions
Sodium Phosphate, Sodium Chloride
Dietary Supplement
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Nov 1, 2026, 4:48 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Highly Processed Foods and Vascular Health

NCT05628350
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
No UPF controlled diet, High UPF controlled diet
Other
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
40 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Nov 1, 2026, 4:48 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Retrospective Evaluation of Athens Complete Health Improvement Program (CHIP) Database

NCT03025451
View directory record Official record
Conditions
Cardiovascular Diseases, Diabetes Mellitus, Hypertension, Dyslipidemias, Overweight and Obesity
Interventions
The Complete Health Improvement Program
Behavioral
Lead sponsor
Ohio University
Other
Eligibility
Not listed
Enrollment
512 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 2, 2018 · Synced Nov 1, 2026, 4:48 PM EST
Completed Phase 4 Interventional Results available

Empiric Versus Selective Prevention Strategies for Kidney Stone Disease

NCT05365477
View directory record Official record
Conditions
Kidney Stones, Nephrolithiasis
Interventions
Empiric Therapy: Diet, Empiric Therapy: Drug, Selective Therapy: Diet, Selective Therapy: Drug
Behavioral · Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Nov 1, 2026, 4:48 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

The Salty Gut: Effects of High Dietary Salt Intake on the Gut Microbiota

NCT04229680
View directory record Official record
Conditions
Cardiovascular Risk Factor
Interventions
High Salt, Recommended Salt
Other
Lead sponsor
University of Delaware
Other
Eligibility
18 Years to 45 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Oct 2, 2023 · Synced Nov 1, 2026, 4:48 PM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

FFA-Induced Hypertension and Endothelial Dysfunction

NCT00589888
View directory record Official record
Conditions
Endothelial Dysfunction, Hypertension
Interventions
Intralipid 20% @ 20cc/hour, Intralipid 20%@ 40cc/hour, Normal Saline, 32-gram oral fat load, 64-gram oral fat load
Drug · Dietary Supplement
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 16, 2018 · Synced Nov 1, 2026, 4:48 PM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Sodium vs Potassium Education to Improve Vascular Health

NCT07221448
View directory record Official record
Conditions
Healthy
Interventions
High potassium dietary education/counseling, Low sodium dietary education/counseling
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 45 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Nov 1, 2026, 4:48 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Preliminary Effect of Food Processing and Sweeteners on Glycemic and Metabolic Measures

NCT05658757
View directory record Official record
Conditions
Blood Sugar; High, Blood Pressure, Dietary Habits
Interventions
Regular sweetened commercial foods, Allulose sweetened commercial foods, Whole and minimally processed and sweetened foods
Other
Lead sponsor
University of California, Irvine
Other
Eligibility
20 Years to 99 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated May 3, 2023 · Synced Nov 1, 2026, 4:48 PM EST
Terminated Not applicable Interventional Accepts healthy volunteers

DASH-Sodium Trial in Adolescents

NCT02993458
View directory record Official record
Conditions
Blood High Pressure
Interventions
DASH diet, Low Na diet, High Na diet, Usual Diet
Other
Lead sponsor
Purdue University
Other
Eligibility
11 Years to 15 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Indianapolis, Indiana • West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 8, 2017 · Synced Nov 1, 2026, 4:48 PM EST
Completed No phase listed Observational Accepts healthy volunteers

Effects of Salt Intake on the Nervous Systems of Patients With Salt-Sensitive High Blood Pressure

NCT00001176
View directory record Official record
Conditions
Hyperaldosteronism, Hypertension
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
Not listed
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1981 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Nov 1, 2026, 4:48 PM EST
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Evaluate VH4524184 Tablet Absorption, Effects of Food, and Interactions With Other Drugs in Healthy Adults

NCT07066722
View directory record Official record
Conditions
HIV Infections
Interventions
VH4524184, Itraconazole, Rifabutin, Phenytoin, Metformin, Digoxin
Drug
Lead sponsor
ViiV Healthcare
Industry
Eligibility
18 Years to 60 Years
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
2
States / cities
Lenexa, Kansas • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Nov 1, 2026, 4:48 PM EST
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Complex Effects of Dietary Manipulation on Metabolic Function, Inflammation and Health

NCT02706262
View directory record Official record
Conditions
Obesity, Insulin Resistance
Interventions
Metabolically abnormal obese - Mediterranean diet, Metabolically abnormal obese - Low carbohydrate ketogenic diet, Metabolically abnormal obese - Plant-based, very-low-fat diet, Annual Follow-up Visits
Other · Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 55 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Nov 1, 2026, 4:48 PM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Dietary Sodium Intake on Vascular Endothelium

NCT01550315
View directory record Official record
Conditions
Postural Tachycardia Syndrome (POTS)
Interventions
Pulsitile Arterial Tonometry (PAT) Protocol, Calf Blood Flow in Reactive Hyperemia (CBF-RH), Evaluation of Forearm-Mediated Dilation
Procedure · Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 5, 2022 · Synced Nov 1, 2026, 4:48 PM EST
Not yet recruiting Not applicable Interventional

Ketogenic Approach to Restore Muscle in Older Patients With Community-Acquired Pneumonia - KARMA-P Trial

NCT07308483
View directory record Official record
Conditions
Pneumonia
Interventions
Ketogenic feeding, Standard feeding
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
55 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Nov 1, 2026, 4:48 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Dietary Salt Intake on Immune Function in Patients With Multiple Sclerosis

NCT02282878
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
High/Low Sodium Diet
Dietary Supplement
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 19, 2021 · Synced Nov 1, 2026, 4:48 PM EST
Terminated Not applicable Interventional

Reducing Insulin, Growth Hormones, and Tumors

NCT03785808
View directory record Official record
Conditions
Diet Modification, Lung Cancer
Interventions
Special Diet Therapy (low-carb), Special Diet Therapy (low-fat), Special Diet Therapy (USDA control)
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 12, 2019 · Synced Nov 1, 2026, 4:48 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Sodium Intake on Calcium Retention in Girls

NCT01564238
View directory record Official record
Conditions
Osteoporosis
Interventions
Low Na diet (1.3 g/d), High sodium diet (3.8 g/d)
Other
Lead sponsor
Purdue University
Other
Eligibility
11 Years to 15 Years · Female only
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2000
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated May 9, 2018 · Synced Nov 1, 2026, 4:48 PM EST
Suspended Not applicable Interventional Accepts healthy volunteers

Dietary Sodium Intake and Blood Pressure in Living Kidney Donors

NCT05041829
View directory record Official record
Conditions
Hypertension, Living Kidney Donor, Dietary Sodium Intake
Interventions
Dietary sodium
Other
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Nov 1, 2026, 4:48 PM EST
Completed Not applicable Interventional Results available

Multicultural Healthy Diet in Chronic Kidney Disease

NCT05504850
View directory record Official record
Conditions
Chronic Kidney Disease
Interventions
Multicultural Health Diet
Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Nov 1, 2026, 4:48 PM EST
Completed Not applicable Interventional

Moderately Carbohydrate-restricted Diet to Treat NAFLD in Adolescents

NCT05268042
View directory record Official record
Conditions
Non-Alcoholic Fatty Liver Disease, Obesity
Interventions
Moderately carbohydrate-restricted diet, Fat-restricted diet
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
10 Years to 17 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Nov 1, 2026, 4:48 PM EST