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ClinicalTrials.gov public records Last synced Oct 30, 2026, 5:50 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 385–408 of 414 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Historical Controls Clear all
Recruiting Phase 2 Interventional

Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk Solid Tumors

NCT04469530
View directory record Official record
Conditions
Solid Tumor
Interventions
Sirolimus, Cyclophosphamide, Etoposide, Celecoxib
Drug
Lead sponsor
Emory University
Other
Eligibility
1 Year to 30 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
5
States / cities
Atlanta, Georgia • St Louis, Missouri • Pittsburgh, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 30, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pain Modulation Effectiveness (PME)

NCT05783362
View directory record Official record
Conditions
Healthy People
Interventions
Conditioned Pain Modulation (CPM)
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 31, 2023 · Synced Oct 30, 2026, 5:50 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Samples From Human Subjects to Facilitate Basic, Translational and Clinical Research

NCT03253705
View directory record Official record
Conditions
Endothelial Dysfunction, Inflammation in Cardiopulmonary and Vascular Disease States, Healthy Volunteers
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 100 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2037
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 23, 2026 · Synced Oct 30, 2026, 5:50 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Controls and Healthy Vasculature Initiative

NCT05403151
View directory record Official record
Conditions
Vascular And Immunologic Diseases, Healthy Volunteers
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 90 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2032
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 30, 2026, 5:50 PM EDT
Completed Not applicable Interventional

The Effect of Exercise on Mood After Traumatic Brain Injury

NCT00571545
View directory record Official record
Conditions
Traumatic Brain Injury, Depression
Interventions
Aerobic exercise, No exercise
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
16 Years to 70 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 6, 2017 · Synced Oct 30, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cardiovascular Mechanisms of Exercise Intolerance in Diabetes and the Role of Sex

NCT03419195
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Healthy, Overweight, Cardiovascular Risk Factor
Interventions
Cardiovascular exercise training
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
30 Years to 55 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 12, 2023 · Synced Oct 30, 2026, 5:50 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

A Study of Tooth Erosion in People With Esophagogastric Cancer

NCT05612048
View directory record Official record
Conditions
Esophagogastric Cancer
Interventions
Survey, Intra-oral camera, Optional Salvia sample
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Oct 30, 2026, 5:50 PM EDT
Terminated Not applicable Interventional

SEAM Trial: Sutureless End to End Anastomosis by Magnetic Compression

NCT05046730
View directory record Official record
Conditions
Retraction of Ileostomy
Interventions
Ileostomy Reversal using Self Forming Magnets (SFM)
Device
Lead sponsor
GI Windows, Inc.
Industry
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
14
States / cities
Orlando, Florida • Boston, Massachusetts • Worcester, Massachusetts + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 30, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pressure Alternating Shoes

NCT06026813
View directory record Official record
Conditions
Foot Ulcer, Diabetic
Interventions
test pressure alternating shoes
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Oct 30, 2026, 5:50 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Cardiovascular and Metabolic Sciences Biorepository

NCT06560424
View directory record Official record
Conditions
Cardiovascular Diseases, Metabolic Disease
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2050
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 30, 2026, 5:50 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Cortical Excitability in Post-traumatic Epilepsy

NCT05517954
View directory record Official record
Conditions
Traumatic Brain Injury, Cortical Excitability, Epilepsy
Interventions
Not listed
Lead sponsor
Mid-Atlantic Epilepsy and Sleep Center, LLC
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 26, 2022 · Synced Oct 30, 2026, 5:50 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Chronic Pain, Opioid Use, and Epidermal Nerve Fiber Density

NCT04801498
View directory record Official record
Conditions
Chronic Pain, Opioid Use, Nerve Disorders
Interventions
Not listed
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Nov 6, 2024 · Synced Oct 30, 2026, 5:50 PM EDT
Enrolling by invitation Not applicable Interventional

CPNF Intervention Development and Testing

NCT07036198
View directory record Official record
Conditions
Alcohol Use
Interventions
Customizable personalized normative feedback (CPNF), Personalized normative feedback (PNF), Attention-Matched Control (AMC)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 24 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 30, 2026, 5:50 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Functional Magnetic Resonance Imaging (fMRI) Findings in Children With Early Exposure to General Anesthesia

NCT01229514
View directory record Official record
Conditions
Exposed to Anesthesia
Interventions
fMRI
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
10 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 2, 2012 · Synced Oct 30, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Eszopiclone on Sleep and Memory in Schizophrenia

NCT01641900
View directory record Official record
Conditions
Schizophrenia
Interventions
eszopiclone, placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 14, 2017 · Synced Oct 30, 2026, 5:50 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mechanisms Preventing Pharyngeal Reflux

NCT05696184
View directory record Official record
Conditions
GERD
Interventions
Concurrent manometry/impedance/pH with video pharyngo-laryngoscopy, Slow and rapid intra-esophageal infusion
Diagnostic Test
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2026
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Oct 30, 2026, 5:50 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Vestibular Consequences of Blast-related Mild Traumatic Brain Injury (TBI)

NCT01021137
View directory record Official record
Conditions
Dizziness, Brain Injury
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
1
States / cities
Mountain Home, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 5, 2019 · Synced Oct 30, 2026, 5:50 PM EDT
Active, not recruiting Not applicable Interventional

Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPG

NCT03033992
View directory record Official record
Conditions
Malignant Glioma, Ependymoma, Diffuse Intrinsic Pontine Glioma
Interventions
Optune System (NovoTTF-200A System, Tumor Treating Fields, TTFields), Concurrent Optune and RT followed by Optune System alone
Device · Combination Product
Lead sponsor
Children's Oncology Group
Network
Eligibility
3 Years to 21 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2032
U.S. locations
11
States / cities
Phoenix, Arizona • Los Angeles, California • Palo Alto, California + 8 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 30, 2026, 5:50 PM EDT
Completed Not applicable Interventional

Effects of Centering Pre-operative Counseling on Patient Reported Anxiety

NCT04068675
View directory record Official record
Conditions
Gynecologic Cancer, Ovarian Cancer, Endometrial Cancer, Uterine Cancer, Cervical Cancer
Interventions
Group pre-operative counseling
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 17, 2021 · Synced Oct 30, 2026, 5:50 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Vestibular Precision: Physiology & Pathophysiology

NCT04890132
View directory record Official record
Conditions
Vestibular Schwannoma, Inner Ear Disease, Dizziness, Neurofibromatosis 2, Vestibular Disorder
Interventions
VOR precision training
Behavioral
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
8 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 16, 2023 · Synced Oct 30, 2026, 5:50 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Blood-Flow Restriction Exercise Following a Knee Replacement

NCT04018638
View directory record Official record
Conditions
Knee Injuries, Knee Osteoarthritis, Knee Arthritis
Interventions
B-FREE
Other
Lead sponsor
Michigan Technological University
Other
Eligibility
40 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
Houghton, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 30, 2026, 5:50 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Prospective Study Of Biomarkers Of Skeletal Muscle Atrophy

NCT02839460
View directory record Official record
Conditions
Sarcopenia
Interventions
Outpatient Muscle Biopsy
Procedure
Lead sponsor
University of Florida
Other
Eligibility
65 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 11, 2019 · Synced Oct 30, 2026, 5:50 PM EDT
Recruiting Not applicable Interventional

Olfactory Biopsies

NCT07021040
View directory record Official record
Conditions
Alzheimer Disease, Smell Loss, Smell Dysfunction
Interventions
olfactory testing, Odor stimulation, Olfactory biopsy
Diagnostic Test · Other · Procedure
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 30, 2026, 5:50 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Exercise in Child Health

NCT05359991
View directory record Official record
Conditions
Cystic Fibrosis, Sickle Cell Disease, SARS CoV 2 Infection
Interventions
Exercise
Other
Lead sponsor
University of California, Irvine
Other
Eligibility
10 Years to 17 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 30, 2026, 5:50 PM EDT