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ClinicalTrials.gov public records Last synced Oct 14, 2026, 3:58 AM EDT

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Showing 265–288 of 851 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Hormone Replacement Therapy (HRT) Clear all
Terminated Not applicable Interventional Results available

Analysis of Lipid Biomarkers of Exposure and Host Response

NCT00493831
View directory record Official record
Conditions
Cigarette Smoking
Interventions
nicotine polacrilex, transdermal system or inhaler
Drug
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 7, 2023 · Synced Oct 14, 2026, 3:58 AM EDT
Recruiting Phase 3 Interventional

Safety Evaluation of Prismocitrate 18 in Patients Receiving CRRT

NCT05399537
View directory record Official record
Conditions
Regional Citrate Anticoagulation (RCA), Continuous Renal Replacement Therapy (CRRT), Acute Kidney Injury (AKI)
Interventions
Prismocitrate 18, PrisMax System Version 3.x with calcium line accessory
Drug · Device
Lead sponsor
Vantive Health LLC
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
14
States / cities
Birmingham, Alabama • Los Angeles, California • Miami, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 14, 2026, 3:58 AM EDT
Completed Phase 1 Interventional

Combined Bone Marrow Transplantation (BMT) and Renal Transplant for Multiple Myeloma (MM) With End Stage Renal Disease (ESRD)

NCT00854139
View directory record Official record
Conditions
Multiple Myeloma, End Stage Renal Disease
Interventions
Cyclophosphamide, anti-thymocyte globulin, Kidney transplant, Thymic irradiation, Bone marrow transplant from a related donor
Drug · Procedure · Radiation
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 4, 2020 · Synced Oct 14, 2026, 3:58 AM EDT
Terminated Not applicable Interventional

Interest in Smokeless Tobacco Product as a Substitution for Cigarettes in Current Smokers

NCT01800500
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
smoking cessation intervention, questionnaire administration, quality-of-life assessment, laboratory biomarker analysis, ecigarettes
Behavioral · Other
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Sep 13, 2022 · Synced Oct 14, 2026, 3:58 AM EDT
Recruiting Not applicable Interventional

E-cigarettes for Harm Reduction Among Smokers With Serious Mental Illness

NCT05815199
View directory record Official record
Conditions
Cigarette Smoking
Interventions
E-cigarette (EC), Nicotine Replacement Therapy (NRT), Harm-Reduction Counseling, Ecological Momentary Intervention (EMI) Text Messaging
Other · Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 14, 2026, 3:58 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Automated Prize-based Contingency Management to Increase Counseling Attendance in Opiate-Replacement-Therapy Patients

NCT01229163
View directory record Official record
Conditions
Opiate-Replacement Therapy
Interventions
Automated Contingency Management (ACM) software
Device
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 14, 2026, 3:58 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

End Nicotine Dependence Clinic

NCT03290430
View directory record Official record
Conditions
Smoking Cessation
Interventions
Group Counseling, Individual Counseling, Phone Counseling, Video Counseling, Texting support, Nicotine Replacement Therapy
Behavioral · Drug
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 14, 2020 · Synced Oct 14, 2026, 3:58 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Effectiveness of Nicotine Replacement Therapy in Reducing the Risk of Nicotine Exposure in Pregnant Minority Smokers

NCT00341432
View directory record Official record
Conditions
Smoking, Pregnancy
Interventions
Nicotine Replacement Therapy
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
21 Years and older · Female only
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
2
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 14, 2026, 3:58 AM EDT
Completed Phase 3 Interventional Results available

Acute Renal Failure Trial Network (ATN) Study

NCT00076219
View directory record Official record
Conditions
Acute Renal Failure
Interventions
renal replacement therapy
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
1,124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
22
States / cities
No. Little Rock, Arkansas • San Francisco, California • West Los Angeles, California + 19 more
Source: ClinicalTrials.gov public record
Updated Aug 23, 2013 · Synced Oct 14, 2026, 3:58 AM EDT
Withdrawn Phase 4 Interventional

Pharmacokinetics, Pharmacodynamics And Safety Study Of Elelyso(tm) In Pediatric Subjects With Type 1 Gaucher Disease

NCT03021941
View directory record Official record
Conditions
Type 1 Gaucher Disease
Interventions
Elelyso 60 units/kg
Drug
Lead sponsor
Pfizer
Industry
Eligibility
Up to 12 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 24, 2019 · Synced Oct 14, 2026, 3:58 AM EDT
Completed Not applicable Interventional Results available

Varenicline and Motivational Advice for Smokers With Substance Use Disorders

NCT00756275
View directory record Official record
Conditions
Smoking Cessation, Nicotine Dependence
Interventions
Nicotine Replacement Treatment (NRT), varenicline, Behavioral counseling for smoking cessation
Drug · Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 75 Years
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 27, 2018 · Synced Oct 14, 2026, 3:58 AM EDT
Withdrawn No phase listed Observational

Pharmacokinetic Assessment of Peramivir in Hospitalized Adults Undergoing Continuous Renal Replacement Therapy

NCT01146353
View directory record Official record
Conditions
Influenza, Renal Failure
Interventions
Not listed
Lead sponsor
Midwestern University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 20, 2018 · Synced Oct 14, 2026, 3:58 AM EDT
Completed Not applicable Interventional Results available

Standard vs. Accelerated Initiation of RRT in Acute Kidney Injury (STARRT-AKI: Principal Trial)

NCT02568722
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
Standard RRT initiation, Accelerated RRT initiation
Other
Lead sponsor
Unity Health Toronto
Other
Eligibility
18 Years and older
Enrollment
3,019 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
6
States / cities
Birmingham, Alabama • Gainesville, Florida • Lexington, Kentucky + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2024 · Synced Oct 14, 2026, 3:58 AM EDT
Completed Phase 3 Interventional Results available

A Study to Evaluate Prospective Efficacy and Safety Data of Current FIX Prophylaxis Replacement Therapy in Adult Hemophilia B Subjects (FIX:C≤2%) or Current FVIII Prophylaxis Replacement Therapy in Adult Hemophilia A Subjects (FVIII:C≤1%)

NCT03587116
View directory record Official record
Conditions
Hemophilia B, Hemophilia A
Interventions
Standard of Care FIX Replacement therapy, Standard of Care FVIII Replacement therapy
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 64 Years · Male only
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
13
States / cities
Palo Alto, California • San Francisco, California • Stanford, California + 7 more
Source: ClinicalTrials.gov public record
Updated Nov 6, 2025 · Synced Oct 14, 2026, 3:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Connect to Quit for Smoking

NCT01299896
View directory record Official record
Conditions
Smoking, Smoking Cessation
Interventions
Coordinated Care, Usual Care
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
633 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 22, 2016 · Synced Oct 14, 2026, 3:58 AM EDT
Completed Phase 4 Interventional Results available

A Text Messaging Program for Smokers in Primary Care

NCT03174158
View directory record Official record
Conditions
Smoking Cessation
Interventions
Mailed nicotine replacement therapy, Text messaging, Brief advice
Drug · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 7, 2020 · Synced Oct 14, 2026, 3:58 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Women's Health Initiative Memory Study (The WHIMS Study)

NCT00685009
View directory record Official record
Conditions
Dementia Syndromes
Interventions
Estrogen hormone therapy, Estrogen plus progesterone hormone therapy, Placebo
Drug
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
65 Years to 79 Years · Female only
Enrollment
7,525 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1996 – 2008
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 19, 2015 · Synced Oct 14, 2026, 3:58 AM EDT
Completed No phase listed Observational

Relieving Vasomotor Symptoms Effectively With Bioidentical Hormone Replacement Therapy: The REVERT Study

NCT01862861
View directory record Official record
Conditions
Menopause
Interventions
Not listed
Lead sponsor
Medimix Specialty Pharmacy, LLC
Industry
Eligibility
30 Years to 65 Years · Female only
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 31, 2014 · Synced Oct 14, 2026, 3:58 AM EDT
Completed Not applicable Interventional

In Vivo Experience With NRT to Increase Adherence and Smoking Abstinence

NCT02938403
View directory record Official record
Conditions
Smoking Reduction or Abstinence
Interventions
In vivo counseling, Standard Smoking Cessation Counseling
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
517 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 7, 2025 · Synced Oct 14, 2026, 3:58 AM EDT
Completed Phase 2 Interventional Results available

Extension Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of SBC-102 (Sebelipase Alfa) in Adult Subjects With Lysosomal Acid Lipase Deficiency

NCT01488097
View directory record Official record
Conditions
Cholesterol Ester Storage Disease (CESD), Lysosomal Acid Lipase Deficiency, LAL-Deficiency
Interventions
sebelipase alfa
Drug
Lead sponsor
Alexion Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
5
States / cities
Eureka, California • Sacramento, California • San Francisco, California + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 20, 2018 · Synced Oct 14, 2026, 3:58 AM EDT
Completed Phase 1 Interventional Results available

Dose Titration Investigation of the Pharmacokinetics of Testosterone Transdermal Systems in Hypogonadal Men

NCT01104246
View directory record Official record
Conditions
Hypogonadism
Interventions
Testerone Transdermal System
Drug
Lead sponsor
Watson Pharmaceuticals
Industry
Eligibility
18 Years and older · Male only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
3
States / cities
Miramar, Florida • Omaha, Nebraska • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 5, 2012 · Synced Oct 14, 2026, 3:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Low-Cost Contingency Management for Smoking Cessation

NCT01040260
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Counseling, Contingency management, Nicotine patches
Other · Behavioral · Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 6, 2018 · Synced Oct 14, 2026, 3:58 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Estrogen Alternatives Study

NCT00108238
View directory record Official record
Conditions
Healthy
Interventions
Estradiol followed by progesterone, Raloxifene
Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2006
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 21, 2009 · Synced Oct 14, 2026, 3:58 AM EDT
Completed Not applicable Interventional Results available

Learn to Quit-HIV Pilot Study

NCT04609514
View directory record Official record
Conditions
HIV/AIDS, Smoking Cessation, Tobacco Use Disorder
Interventions
Learn to Quit-HIV, QuitGuide, Nicotine patch, Smartphone coaching
Device · Behavioral · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 19, 2023 · Synced Oct 14, 2026, 3:58 AM EDT