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ClinicalTrials.gov public records Last synced Oct 14, 2026, 4:27 PM EDT

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Showing 457–480 of 851 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Hormone Replacement Therapy (HRT) Clear all
Completed Phase 3 Interventional Results available

Smoking Cessation Versus Long-term Nicotine Replacement Among High-risk Smokers

NCT02148445
View directory record Official record
Conditions
Smoking, Pulmonary Disease, Chronic Obstructive, Tobacco Use Disorder
Interventions
Standard Smoking Cessation, Extended Nicotine Replacement Therapy, Nicotine replacement therapy
Other · Drug
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
398 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 6, 2017 · Synced Oct 14, 2026, 4:27 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Menopause Interactive Decision Aid System

NCT00345072
View directory record Official record
Conditions
Menopause
Interventions
Web-based decision aid system
Device
Lead sponsor
Rhode Island Hospital
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
296 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2003
U.S. locations
2
States / cities
Boston, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 27, 2006 · Synced Oct 14, 2026, 4:27 PM EDT
Completed Phase 4 Interventional

Pilot Study Evaluating Doxercalciferol Replacement Therapy in Kidney Transplant Recipients

NCT00889629
View directory record Official record
Conditions
Chronic Kidney Disease, Kidney Transplantation
Interventions
Doxercalciferol, placebo, 25-OH Vitamin D3
Drug
Lead sponsor
Mariana Markell
Other
Eligibility
18 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Feb 22, 2019 · Synced Oct 14, 2026, 4:27 PM EDT
Completed Not applicable Interventional Results available

Integrated Treatment for Smoking Cessation & Anxiety in People With HIV

NCT01393301
View directory record Official record
Conditions
Nicotine Dependence, Symptoms of Anxiety, HIV
Interventions
Integrated cognitive-behavioral therapy for smoking cessation and anxiety, Control
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 3, 2023 · Synced Oct 14, 2026, 4:27 PM EDT
Completed Phase 1 Interventional Results available

Mindfulness-Based Ecological Momentary Intervention For Smoking Cessation Among Cancer Survivors

NCT06476548
View directory record Official record
Conditions
Any Cancer Type
Interventions
EMI
Device
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Oct 14, 2026, 4:27 PM EDT
Completed Phase 4 Interventional Results available

The END Perioperative Smoking Pilot Study

NCT02482233
View directory record Official record
Conditions
Smoking, Nicotine Addiction, Surgery
Interventions
ENDD (NJOY), NRT (NicoDerm CQ), telephone counseling, brief advice, brochure
Behavioral · Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Oct 14, 2026, 4:27 PM EDT
Completed Not applicable Interventional

A Study of Intrathecal Enzyme Therapy for Cognitive Decline in MPS I

NCT00852358
View directory record Official record
Conditions
Cognitive Decline, Mucopolysaccharidosis I, Hurler-Scheie Syndrome, Scheie Syndrome, Lysosomal Storage Disease
Interventions
laronidase
Drug
Lead sponsor
Patricia I. Dickson, M.D.
Individual
Eligibility
6 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
3
States / cities
Oakland, California • Torrance, California • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 26, 2016 · Synced Oct 14, 2026, 4:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reproductive Capacity and Iron Burden in Thalassemia

NCT02308904
View directory record Official record
Conditions
THALASSEMIA MAJOR
Interventions
Blood Draw/Semen Exam, Retrospective data/Chart Review/Relevant Clinical Results, Pituitary MRI
Other
Lead sponsor
UCSF Benioff Children's Hospital Oakland
Other
Eligibility
12 Years and older
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Dec 23, 2020 · Synced Oct 14, 2026, 4:27 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Preloading With Nicotine Replacement Therapy in HIV-positive Smokers to Improve Self-Efficacy and Quit Attempts

NCT04994444
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Nicoderm CQ 21Mg/24Hr Transdermal System
Drug
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 6, 2025 · Synced Oct 14, 2026, 4:27 PM EDT
Completed Not applicable Interventional

Motivational Interviewing Compared to Psychoeducation for Smoking Precontemplators With SMI

NCT01982617
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Motivational Interviewing, Psychoeducation
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 13, 2013 · Synced Oct 14, 2026, 4:27 PM EDT
Recruiting No phase listed Observational

Menopausal Hormone Therapy And Left Ventricular Function

NCT07242391
View directory record Official record
Conditions
Menopause, Left Ventricular Dysfunction
Interventions
Menopausal Hormone Therapy
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
45 Years to 60 Years · Female only
Enrollment
50 participants
Timeline
2026 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 14, 2026, 4:27 PM EDT
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers

Mobile App for Smoking Cessation and Mental Health

NCT04887558
View directory record Official record
Conditions
Smoking Cessation, Mental Illness
Interventions
Smart-T Mental Health+ and NRT, QuitGuide + NRT
Combination Product
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 100 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 14, 2026, 4:27 PM EDT
Completed Not applicable Interventional

Project 1, Study 2: The Combined Impact of Nicotine Replacement and Spectrum Cigarettes

NCT02301325
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Smoking research cigarettes with or without NRT
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Oct 14, 2026, 4:27 PM EDT
Completed Not applicable Interventional

Clinical Trial of an Automated Smartphone Based Smoking Cessation Treatment

NCT02930200
View directory record Official record
Conditions
Smoking Cessation
Interventions
Treatment as Usual, QuitGuide, Smart-T
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 20, 2019 · Synced Oct 14, 2026, 4:27 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Bio-Behavioral Predictors of the Efficacy of Nicotine Replacement Therapy (NRT)

NCT00326781
View directory record Official record
Conditions
Smoking
Interventions
Nicoderm Transdermal Patch, Nicotine Nasal Spray
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 75 Years
Enrollment
674 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2004
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 24, 2010 · Synced Oct 14, 2026, 4:27 PM EDT
Completed Not applicable Interventional Results available

Take a Break (TAB): mHealth-assisted Skills Building Challenge for Unmotivated Smokers

NCT02973425
View directory record Official record
Conditions
Smoking Cessation
Interventions
Take a Break as an augmentation to NRT-sampling in Motivation Phase, NRT and mHealth assessment tool without feedback
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
433 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
4
States / cities
Worcester, Massachusetts • Great Neck, New York
Source: ClinicalTrials.gov public record
Updated Aug 11, 2022 · Synced Oct 14, 2026, 4:27 PM EDT
Completed Not applicable Interventional

More Frequent In-Center Hemodialysis in Pediatric End Stage Renal Disease

NCT01352455
View directory record Official record
Conditions
Pediatric End Stage Renal Disease, Hemodialysis
Interventions
Hemodialysis
Procedure
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
3 Years to 21 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Cincinnati, Ohio • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 31, 2013 · Synced Oct 14, 2026, 4:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Growth Hormone, Cardiovascular Risk, and Visceral Adiposity

NCT00131378
View directory record Official record
Conditions
Obesity
Interventions
Nutropin AQ growth hormone, Placebo Growth Hormone
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years
Enrollment
142 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 11, 2016 · Synced Oct 14, 2026, 4:27 PM EDT
Completed Phase 4 Interventional Results available

Counseling and Nicotine Replacement Therapy in Helping Adult Smokers Quit Smoking

NCT00365508
View directory record Official record
Conditions
Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer, Head and Neck Cancer, Kidney Cancer, Leukemia, Liver Cancer, Lung Cancer, Pancreatic Cancer, Tobacco Use Disorder
Interventions
nicotine lozenge, nicotine patch
Drug
Lead sponsor
Fox Chase Cancer Center
Other
Eligibility
18 Years and older
Enrollment
642 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
10
States / cities
Washington D.C., District of Columbia • Miami Beach, Florida • Augusta, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 29, 2016 · Synced Oct 14, 2026, 4:27 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Development of a Mobile Health Intervention for Electronic Cigarette Use Among Young Adults

NCT06395415
View directory record Official record
Conditions
Electronic Nicotine Delivery Systems, Tobacco Products, Cigarette Smoking
Interventions
EQUIP, Standard Care
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 26 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 14, 2026, 4:27 PM EDT
Completed Not applicable Interventional

Smoking Cessation in NYC

NCT04489524
View directory record Official record
Conditions
Smoking Cessation
Interventions
individualized counselor-led MI sessions, general health education session, NRT
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 110 Years
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Oct 14, 2026, 4:27 PM EDT
Completed Not applicable Interventional Results available

Quit & Fit 2.0: Feasibility and Usability Testing

NCT05878990
View directory record Official record
Conditions
Smoking Cessation
Interventions
Culturally-tailored Tobacco Treatment, Culturally-tailored Content Newsletters, Control Preference Scale, Active Content Newsletter or Passive Content Newsletter
Behavioral
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years to 69 Years · Female only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Nutley, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 17, 2024 · Synced Oct 14, 2026, 4:27 PM EDT
Completed Phase 4 Interventional Results available

Pharmacokinetics of Tamiflu® (Oseltamivir) in Patients Receiving Extracorporeal Membrane Oxygenation (ECMO)and or Continuous Venovenous Hemodialysis (CVVHD)

NCT01048879
View directory record Official record
Conditions
Critically Ill Renal Failure Requiring CVVHD and Oseltamivir, Critically Ill Requiring ECMO and Oseltamivir
Interventions
pharmacokinetic blood sampling, pharmacokinetic blood and dialysate sampling
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
Not listed
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 21, 2012 · Synced Oct 14, 2026, 4:27 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Smoking Relapse Prevention in Schizophrenia

NCT00320697
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Smokers
Interventions
bupropion + nicotine patch + nicotine gum or lozenges, Placebo pill + placebo patch
Drug
Lead sponsor
North Suffolk Mental Health Association
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 27, 2016 · Synced Oct 14, 2026, 4:27 PM EDT