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ClinicalTrials.gov public records Last synced Oct 2, 2026, 1:24 PM EDT

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Showing 73–96 of 147 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Hormone Replacement Therapy - HRT Clear all
Completed Phase 3 Interventional Results available

Comparison of Chronocort Versus Standard Hydrocortisone Replacement Therapy in Participants Aged 16 Years and Over With Congenital Adrenal Hyperplasia

NCT05063994
View directory record Official record
Conditions
Congenital Adrenal Hyperplasia
Interventions
Chronocort, Cortef, Placebo
Drug · Other
Lead sponsor
Neurocrine UK Limited
Industry
Eligibility
16 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
11
States / cities
Los Angeles, California • Orange, California • Jacksonville, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 2, 2026, 1:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Changes in Breast Density and Breast Cancer Risk in Women With Breast Cancer and in Healthy Women

NCT00445445
View directory record Official record
Conditions
Breast Cancer
Interventions
physiologic testing, screening questionnaire administration, breast imaging study, radiomammography, study of high risk factors
Other · Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
40 Years and older · Female only
Enrollment
2,201 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
8
States / cities
Cleveland, Ohio • Mayfield Heights, Ohio • Mentor, Ohio + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 11, 2020 · Synced Oct 2, 2026, 1:24 PM EDT
Completed Phase 4 Interventional Results available

A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men

NCT03518034
View directory record Official record
Conditions
Hypogonadism, Cardiovascular Diseases
Interventions
AndroGel®, Placebo
Drug
Lead sponsor
AbbVie
Industry
Eligibility
45 Years to 80 Years · Male only
Enrollment
5,246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
379
States / cities
Alabaster, Alabama • Birmingham, Alabama • Decatur, Alabama + 262 more
Source: ClinicalTrials.gov public record
Updated Mar 13, 2024 · Synced Oct 2, 2026, 1:24 PM EDT
Withdrawn Phase 3 Interventional

Open-label Comparison of Chronocort® Versus Standard Glucocorticoid Replacement Therapy

NCT03532022
View directory record Official record
Conditions
Congenital Adrenal Hyperplasia
Interventions
Chronocort®, Standard Care
Drug
Lead sponsor
Neurocrine UK Limited
Industry
Eligibility
16 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Morehead City, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 2, 2026, 1:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study of Early Hormone Replacement Therapy on Risk Factors for Sudden Cardiac Death

NCT00580775
View directory record Official record
Conditions
Menopausal Women
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
42 Years to 58 Years · Female only
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2010
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 22, 2015 · Synced Oct 2, 2026, 1:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Development and Evaluation of a Hormone Replacement Therapy Decision-Aid

NCT00012909
View directory record Official record
Conditions
Menopause, Hormone Replacement Therapy
Interventions
Hormone Replacement Therapy Decision-Aid
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
45 Years to 74 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Ends 2004
U.S. locations
3
States / cities
Hines, Illinois • Milwaukee, Pennsylvania • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 2, 2026, 1:24 PM EDT
Completed Phase 3 Interventional Results available

A Safety, Tolerability and Efficacy Study of TransCon hGH in Children With Growth Hormone Deficiency

NCT03305016
View directory record Official record
Conditions
Growth Hormone Deficiency, Pediatric, Endocrine System Diseases, Hormone Deficiency, Pituitary Diseases
Interventions
TransCon hGH
Drug
Lead sponsor
Ascendis Pharma Endocrinology Division A/S
Industry
Eligibility
6 Months to 17 Years
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
21
States / cities
Birmingham, Alabama • Los Angeles, California • Sacramento, California + 17 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 2, 2026, 1:24 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

ELITE: Early Versus Late Intervention Trial With Estradiol

NCT00114517
View directory record Official record
Conditions
Atherosclerosis
Interventions
17B-estradiol, Placebo
Drug · Other
Lead sponsor
University of Southern California
Other
Eligibility
Female only
Enrollment
643 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 18, 2023 · Synced Oct 2, 2026, 1:24 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Estrogen Alternatives Study

NCT00108238
View directory record Official record
Conditions
Healthy
Interventions
Estradiol followed by progesterone, Raloxifene
Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2006
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 21, 2009 · Synced Oct 2, 2026, 1:24 PM EDT
Terminated Not applicable Interventional

Clinical Study of PGT-A Versus PGT-A+ERA

NCT03530254
View directory record Official record
Conditions
Infertility of Uterine Origin
Interventions
PGT-A, ERA Test
Diagnostic Test
Lead sponsor
Igenomix
Industry
Eligibility
Female only
Enrollment
368 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
Newport Beach, California • Reading, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 4, 2022 · Synced Oct 2, 2026, 1:24 PM EDT
Completed Phase 1 Interventional

VRS-317 in Adult Subjects With Growth Hormone Deficiency

NCT01359488
View directory record Official record
Conditions
Growth Hormone Deficiency
Interventions
VRS-317
Drug
Lead sponsor
Versartis Inc.
Industry
Eligibility
25 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 23, 2012 · Synced Oct 2, 2026, 1:24 PM EDT
Completed Phase 3 Interventional Results available

A Trial Investigating the Safety, Tolerability and Efficacy of TransCon PTH Administered Daily in Adults With Hypoparathyroidism

NCT04701203
View directory record Official record
Conditions
Hypoparathyroidism, Endocrine System Diseases, Parathyroid Diseases
Interventions
TransCon PTH, Placebo
Combination Product
Lead sponsor
Ascendis Pharma Bone Diseases A/S
Industry
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
9
States / cities
San Francisco, California • Chicago, Illinois • Rochester, Minnesota + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 2, 2026, 1:24 PM EDT
Completed Phase 2 Interventional Results available

Testosterone and Long Pulse Stimulation After SCI

NCT03345576
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Testosterone and LPWS, Testosterone and standard NMES
Device · Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years · Male only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 2, 2026, 1:24 PM EDT
Completed Phase 2 Interventional Results available

Effects of Testosterone Replacement on Pain Sensitivity and Pain Perception

NCT00351819
View directory record Official record
Conditions
Pain, Hypogonadism
Interventions
AndroGel, Placebo
Drug · Other
Lead sponsor
Boston University
Other
Eligibility
18 Years to 100 Years · Male only
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2017 · Synced Oct 2, 2026, 1:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Radiologic Evaluation and Breast Density (READ)

NCT00117663
View directory record Official record
Conditions
Breast Cancer
Interventions
temporary discontinuation of hormone therapy for 1 month, temporary discontinuation of hormone therapy for 2 months
Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
45 Years to 80 Years · Female only
Enrollment
1,704 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Oct 2, 2026, 1:24 PM EDT
Completed Not applicable Interventional Results available

Testosterone Replacement Therapy in Advanced Chronic Kidney Disease

NCT00645658
View directory record Official record
Conditions
Kidney Failure, Kidney Diseases
Interventions
Testim, 1% testosterone gel
Drug
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
45 Years to 80 Years · Male only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
2
States / cities
Palo Alto, California • San Jose, California
Source: ClinicalTrials.gov public record
Updated Aug 26, 2024 · Synced Oct 2, 2026, 1:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Estrogen Use in Protection From Cognitive Decline

NCT00097058
View directory record Official record
Conditions
Aging, Menopause
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2014
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Nov 19, 2014 · Synced Oct 2, 2026, 1:24 PM EDT
Terminated Not applicable Interventional

Estrogen Replacement to Reduce Risk of Neurologic Injury After Coronary Artery Bypass Graft Surgery

NCT00123539
View directory record Official record
Conditions
Coronary Disease, Cardiovascular Diseases, Heart Diseases, Neurologic Manifestations
Interventions
Estrogen Replacement Therapy, Surgery
Drug · Procedure
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
55 Years and older · Female only
Enrollment
334 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 29, 2016 · Synced Oct 2, 2026, 1:24 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Hormone Replacement Therapy (HRT) Website Tool

NCT00319072
View directory record Official record
Conditions
Communication, Menopause, Hormone Replacement Therapy
Interventions
TalkToYourDoc(sm) hormone therapy module
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
45 Years to 74 Years · Female only
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 27, 2006 · Synced Oct 2, 2026, 1:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neural Changes in the Aging Auditory System

NCT00264407
View directory record Official record
Conditions
Progesterone, Estrogens, Hearing, Psychoacoustics, Auditory Perceptual Disorders
Interventions
Hormone Replacement Therapy - HRT
Drug
Lead sponsor
University of Rochester
Other
Eligibility
60 Years to 86 Years · Female only
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
2
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 12, 2005 · Synced Oct 2, 2026, 1:24 PM EDT
Completed Phase 3 Interventional Results available

A Trial to Investigate Long Term Efficacy and Safety of Lonapegsomatropin in Adults With Growth Hormone Deficiency

NCT05171855
View directory record Official record
Conditions
Adult Growth Hormone Deficiency, Endocrine System Diseases, Hormone Deficiency
Interventions
Lonapegsomatropin
Drug
Lead sponsor
Ascendis Pharma Endocrinology Division A/S
Industry
Eligibility
23 Years to 81 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
15
States / cities
Phoenix, Arizona • Torrance, California • Chicago, Illinois + 12 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 2, 2026, 1:24 PM EDT
Completed Phase 2Phase 3 Interventional

Alzheimer's Disease: Therapeutic Potential of Estrogen

NCT00066157
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Transdermal estradiol, Medroxyprogesterone, Placebo Patch, Placebo
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
55 Years to 90 Years · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 23, 2018 · Synced Oct 2, 2026, 1:24 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

A Pharmacokinetic (PK) Study to Compare the Absorption of Two Formulations of Transdermal Testosterone Spray and Intrinsa®

NCT01096329
View directory record Official record
Conditions
Hypoactive Sexual Desire Disorder
Interventions
Testosterone Spray 5% and 1%, Intrinsa® Patch and Testosterone Spray 5%, Intrinsa® Patch and Testosterone Spray 1%
Drug
Lead sponsor
VIVUS LLC
Industry
Eligibility
45 Years to 65 Years · Female only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2010
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 8, 2011 · Synced Oct 2, 2026, 1:24 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Cardiac Hormone Replacement With Brain Natriuretic Peptide (BNP) in Heart Failure

NCT00252187
View directory record Official record
Conditions
Congestive Heart Failure, Cardiomyopathy
Interventions
B-type Natriuretic Peptide (BNP), Placebo
Drug · Other
Lead sponsor
Horng Chen
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2010
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 20, 2012 · Synced Oct 2, 2026, 1:24 PM EDT