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ClinicalTrials.gov public records Last synced Oct 18, 2026, 3:38 AM EDT

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Showing 25–48 of 181 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Human Milk Clear all
Completed Not applicable Interventional Accepts healthy volunteers

BIG Study (Brain, Immune, and Gut Health Evaluation of Infants/Young Children Fed Infant Formula, and Later Supplemental Toddler Nutrition, With 5 Specific HMOs)

NCT04957992
View directory record Official record
Conditions
Growth
Interventions
Control Infant Formula, Control Toddler Drink, Experimental Infant Formula, Experimental Toddler Drink, Human Milk, Human Milk Supplemental Formula, Human Milk Toddler Drink
Other
Lead sponsor
Abbott Nutrition
Industry
Eligibility
0 Days to 14 Days
Enrollment
607 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
42
States / cities
Phoenix, Arizona • Glenwood, Arkansas • Hot Springs, Arkansas + 35 more
Source: ClinicalTrials.gov public record
Updated Jun 27, 2025 · Synced Oct 18, 2026, 3:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Growth and Tolerance of Infants Fed Milk-Based Infant Formula

NCT03967132
View directory record Official record
Conditions
Gastro-Intestinal Tolerance
Interventions
Control Infant Formula, Experimental Infant Formula, Reference Group
Other
Lead sponsor
Abbott Nutrition
Industry
Eligibility
Up to 14 Days
Enrollment
189 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
19
States / cities
Tucson, Arizona • Sacramento, California • Norwich, Connecticut + 16 more
Source: ClinicalTrials.gov public record
Updated Sep 22, 2020 · Synced Oct 18, 2026, 3:38 AM EDT
Not yet recruiting Not applicable Interventional

Vitamin A Supplementation and Breast Milk Vitamin A Levels in Mothers of Preterm Infants

NCT07736768
View directory record Official record
Conditions
Premature, Preterm Infant Health, Vitamin A Deficiency, Human Milk, Breastfeeding
Interventions
Oral multivitamin containing vitamin A
Dietary Supplement
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 18, 2026, 3:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Phase II Growth and Safety Study of an Infant Formula for Healthy Term Infants

NCT04593147
View directory record Official record
Conditions
Infant Development
Interventions
BBN, Brand
Other
Lead sponsor
Building Block Nutritionals, LLC
Industry
Eligibility
1 Day to 14 Days
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Nov 15, 2021 · Synced Oct 18, 2026, 3:38 AM EDT
Recruiting No phase listed Observational

At-the-Breast vs. Expressed Human Milk: Genesis of Infant Nutrition (BEGIN)

NCT06691932
View directory record Official record
Conditions
Breast Feeding, Exclusive Breastfeeding
Interventions
Not listed
Lead sponsor
University of Rochester
Other
Eligibility
0 Days to 40 Years
Enrollment
240 participants
Timeline
2024 – 2029
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Oct 18, 2026, 3:38 AM EDT
Not yet recruiting Phase 4 Interventional

Impact of Probiotics on Gut Microbiome During Antibiotic Prophylaxis in Elective Orthopedic Surgery

NCT06791993
View directory record Official record
Conditions
Dysbiosis, Gut -microbiota, Microbiome Analysis, Probiotic, Antibiotic Prophylaxis
Interventions
Placebo Capsule, Probiotic with Human Milk Oligosaccharides (HMO)
Drug · Dietary Supplement
Lead sponsor
Acibadem Maslak Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 24, 2025 · Synced Oct 18, 2026, 3:38 AM EDT
Recruiting Not applicable Interventional

Targeted Fortification of Donor Breast Milk in Preterm Infants

NCT04294368
View directory record Official record
Conditions
Prematurity; Extreme, Failure to Thrive in Newborn, Growth Retardation, Growth Failure, Infant Nutrition Disorders
Interventions
Similac Human Milk Fortifier Extensively Hydrolyzed Protein Concentrated Liquid, Similac Liquid Protein Fortifier, Nestle Microlipid, Medica Nutrition SolCarb, Similac Human Milk Fortifier Extensively Hydrolyzed Protein Concentrated Liquid (Targeted Fortification), Similac Liquid Protein Fortifier (Targeted Fortification), Nestle Microlipid (Targeted Fortification), Medica Nutrition SolCarb (Targeted Fortification), Analysis with Miris (AB) Human Milk Analyzer
Dietary Supplement · Other
Lead sponsor
Columbia University
Other
Eligibility
1 Day to 21 Days
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 18, 2026, 3:38 AM EDT
Completed No phase listed Observational Results available

Dietary Supplement With and Without a Probiotic and/or Antibiotic

NCT05141903
View directory record Official record
Conditions
Healthy Adults
Interventions
Antibiotic, HMO Concentrate, Probiotic, Food Supplement
Dietary Supplement
Lead sponsor
Prolacta Bioscience
Industry
Eligibility
18 Years to 75 Years
Enrollment
92 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cypress, California
Source: ClinicalTrials.gov public record
Updated Feb 17, 2025 · Synced Oct 18, 2026, 3:38 AM EDT
Completed Phase 1 Interventional

Siliphos in Advanced Hepatocellular Carcinoma

NCT01129570
View directory record Official record
Conditions
Advanced Hepatocellular Carcinoma
Interventions
Silybin
Drug
Lead sponsor
Abby Siegel
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 25, 2013 · Synced Oct 18, 2026, 3:38 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Effects of Natural Sugars in Breast Milk on Healthy Infant Growth and Development

NCT04434027
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 59 Years · Female only
Enrollment
221 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 28, 2025 · Synced Oct 18, 2026, 3:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

What's Hopping? Cricket Protein and Human Gut Microbiota

NCT03383341
View directory record Official record
Conditions
Healthy
Interventions
Cricket Protein Powder, Placebo control
Dietary Supplement · Other
Lead sponsor
Colorado State University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 4, 2019 · Synced Oct 18, 2026, 3:38 AM EDT
Completed Not applicable Interventional

Donor Human Milk in Young Children Receiving Bone Marrow Transplantation

NCT02470104
View directory record Official record
Conditions
Bone Marrow Transplant - Autologous or Allogeneic
Interventions
Breastmilk
Dietary Supplement
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Up to 4 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 20, 2020 · Synced Oct 18, 2026, 3:38 AM EDT
Terminated Phase 2 Interventional

Study To Evaluate The Safety And Efficacy of PBCLN-010 In Combination With PBCLN-014 in Participants Receiving Allogeneic Hematopoietic Cell Transplantation

NCT06102213
View directory record Official record
Conditions
Hematologic Malignancy
Interventions
B. infantis (PBCLN-014) and Human Milk Oligosaccharides (HMO) (PBCLN-010)
Drug
Lead sponsor
Prolacta Bioscience
Industry
Eligibility
18 Years to 75 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Oct 18, 2026, 3:38 AM EDT
Terminated Not applicable Interventional

Feeding Study in VLBW Premature Infants

NCT05744193
View directory record Official record
Conditions
VLBW - Very Low Birth Weight Infant
Interventions
Exempt Infant Formula
Other
Lead sponsor
Mead Johnson Nutrition
Industry
Eligibility
168 Days to 224 Days
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
6
States / cities
Birmingham, Alabama • Augusta, Georgia • Indianapolis, Indiana + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 9, 2024 · Synced Oct 18, 2026, 3:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The EFFECT Study: Probiotic and HMO Supplementation in Infants

NCT03994315
View directory record Official record
Conditions
Infant Gut Microbiome
Interventions
B. infantis EVC001, Lacto-N-tetraose (LNT)
Other
Lead sponsor
Evolve BioSystems, Inc.
Industry
Eligibility
Up to 60 Days
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 9, 2020 · Synced Oct 18, 2026, 3:38 AM EDT
Active, not recruiting Not applicable Interventional

Early Human Milk Fortification After Early, Exclusive, Enteral Nutrition in Very Preterm Infants

NCT05525585
View directory record Official record
Conditions
Prematurity, Light-For-Dates, Enteral Feeding Intolerance
Interventions
Early HMF, Delayed HMF
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Day to 4 Days
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 18, 2026, 3:38 AM EDT
Completed Phase 2 Interventional Results available

Impact of Oxytocin on Obstructive Sleep Apnea Induced Changes in Sleep

NCT03148899
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Oxytocin Intranasal Spray, Placebo Intranasal Spray
Drug
Lead sponsor
George Washington University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 31, 2023 · Synced Oct 18, 2026, 3:38 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Sources of Bacterial Contamination in Human Milk Samples From the MiLC Trial

NCT03371511
View directory record Official record
Conditions
Bacterial Communities
Interventions
Not listed
Lead sponsor
Cornell University
Other
Eligibility
18 Years and older · Female only
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Ithaca, New York
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Oct 18, 2026, 3:38 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Pediatric Obesity and the Infant Microbiome (BEACH)

NCT02843087
View directory record Official record
Conditions
Pediatric Obesity
Interventions
Not listed
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 25, 2024 · Synced Oct 18, 2026, 3:38 AM EDT
Completed No phase listed Observational Results available

Growth and Microbiome Development in Very Low Birth Weight Infants Fed Primarily Mother's Own Milk vs. Donor Human Milk

NCT02573779
View directory record Official record
Conditions
Infant, Very Low Birth Weight
Interventions
Observational - no intervention
Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Up to 3 Days
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Oct 18, 2026, 3:38 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Metformin to Augment Low Milk Supply (MALMS) Study

NCT02179788
View directory record Official record
Conditions
Low Milk Supply, Pre-diabetes, Insulin Resistance, Suppressed Lactation
Interventions
Standard care, Metformin, Placebo
Behavioral · Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
20 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Oct 18, 2026, 3:38 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Researchers At UC San Diego Are Learning About the Benefits of Human Milk and How It Influences Infant and Child Health

NCT05553743
View directory record Official record
Conditions
Breastfeeding, COVID-19 Infection, COVID-19 Vaccine, Remdesivir, Antibiotics
Interventions
COVID-19 Exposure, Antibiotic
Biological · Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2040
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 31, 2025 · Synced Oct 18, 2026, 3:38 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

The Impact of a Human Breast Milk Supplement on Epigenetic and Cellular Markers

NCT05297097
View directory record Official record
Conditions
Aging
Interventions
Trulacta breastmilk supplement
Dietary Supplement
Lead sponsor
TruDiagnostic
Industry
Eligibility
18 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Sep 8, 2022 · Synced Oct 18, 2026, 3:38 AM EDT
Recruiting Not applicable Interventional

Individualized Nutrition to Optimize Preterm Infant Growth and Neurodevelopment

NCT06266455
View directory record Official record
Conditions
Very Preterm Maturity of Infant, Very Low Birth Weight Infant
Interventions
Standardized Fortification, Adjustable Fortification
Dietary Supplement
Lead sponsor
Children's National Research Institute
Other
Eligibility
Up to 4 Weeks
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2034
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Oct 18, 2026, 3:38 AM EDT