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Showing 25–48 of 261 matching trials from the live ClinicalTrials.gov search.
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Efficacy and Safety Assessment of Experimental Bleaching Agents

NCT06802614
Conditions
Tooth Discoloration, Dentin Sensitivity, Patient Satisfaction
Interventions
BLEACHING GEL A, 5% NF_TiO2, BLEACHING GEL B, VISIBLE LIGHT IRRADIATION, Whiteness HP 35%, Whiteness HP Automixx 6%
Device · Radiation
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 65 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Conditions
Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer, Pancreatic Neoplasms
Interventions
PEGPH20, Pembrolizumab
Drug · Biological
Lead sponsor
Pancreatic Cancer Research Team
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
5
States / cities
Gilbert, Arizona • Los Angeles, California • New Brunswick, New Jersey + 2 more
Conditions
Perioral Rhytids
Interventions
Restalyne Silk, Belotero Balance
Drug
Lead sponsor
The Maas Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2016
U.S. locations
1
States / cities
San Francisco, California
Conditions
Recovery Following Partial Medial Meniscectomy
Interventions
Chondrogen, Placebo
Drug
Lead sponsor
Mesoblast International Sàrl
Industry
Eligibility
18 Years to 60 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
4
States / cities
Los Angeles, California • Indianapolis, Indiana • Bloomington, Minnesota + 1 more
Conditions
Genitourinary Syndrome of Menopause (GSM)
Interventions
Vaginal estrogen tablet, Via Solv Wellness (Hyaluronic Acid Therapy)
Drug · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
45 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Conditions
Corneal Epithelial Wound
Interventions
Acuvue Oasys, Ocular Bandage Gel
Device
Lead sponsor
Eyegate Pharmaceuticals, Inc.
Industry
Eligibility
22 Years to 50 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Houston, Texas
Conditions
Metastatic Breast Cancer
Interventions
Eribulin mesylate, Biologic: PEGylated recombinant human hyaluronidase (PEGPH20), Biologic: PEGylated recombinant human hyaluronidase
Drug · Other
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
7
States / cities
Whittier, California • Atlanta, Georgia • Newnan, Georgia + 4 more
Completed Not applicable Interventional Accepts healthy volunteers

A Study of Subcutaneous Injection in Healthy Participants

NCT06516913
Conditions
Healthy
Interventions
Harvard Apparatus syringe pump
Device
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
22 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Dallas, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Prospective Evaluation of Infraorbital Filler Injection

NCT05694286
Conditions
Dermal Filler, Rejuvenation
Interventions
Juvederm Volbella XC hyaluronic acid dermal filler injection
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
22 Years to 65 Years · Female only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

RHA® Redensity Eye Versus No-treatment for the Infra-Orbital Hollows

NCT04577898
Conditions
Infra-orbital Hollows, Tear-trough Deformity, Wrinkle
Interventions
RHA® Redensity Eye
Device
Lead sponsor
Teoxane SA
Industry
Eligibility
22 Years and older
Enrollment
248 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
4
States / cities
Encino, California • Santa Monica, California • Coral Gables, Florida + 1 more
Conditions
Knee Osteoarthritis
Interventions
BMAC injection, PRP injection, Gel-One® hyaluronate injection
Biological · Device
Lead sponsor
OhioHealth
Other
Eligibility
40 Years to 70 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Completed Not applicable Interventional Accepts healthy volunteers Results available

Intramuscular Heating Rates of a Chattanooga Intelect XT Therapeutic Ultrasound

NCT03816709
Conditions
Ultrasound Therapy; Complications
Interventions
Therapeutic Ultrasound
Device
Lead sponsor
North Dakota State University
Other
Eligibility
18 Years to 35 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Fargo, North Dakota
Conditions
Knee Osteoarthritis
Interventions
HYMOVIS, Placebo
Device
Lead sponsor
Fidia Farmaceutici s.p.a.
Industry
Eligibility
40 Years and older
Enrollment
332 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
21
States / cities
Birmingham, Alabama • Brimingham, Alabama • Phoenix, Arizona + 17 more
Completed Phase 4 Interventional Results available

DisCoVisc Versus DuoVisc, Healon5 and AmVisc Plus

NCT00712244
Conditions
Cataract
Interventions
DisCoVisc, DuoVisc, Healon5, Amvisc Plus
Device
Lead sponsor
Alcon Research
Industry
Eligibility
50 Years and older
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Dehydration
Interventions
hylenex-facilitated subcutaneous Lactated Ringer's infusion
Drug
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
2
States / cities
Lincoln, Nebraska • Neptune City, New Jersey
Completed Phase 4 Interventional Results available

A Treatment for Severe Inflammatory Acne Subjects

NCT02899000
Conditions
Acne Vulgaris
Interventions
Adapalene 0.3% / benzoyl peroxide 2.5% emulsion gel, Oral doxycycline hyclate
Drug
Lead sponsor
Galderma R&D
Industry
Eligibility
12 Years and older
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Fort Worth, Texas
Suspended Not applicable Interventional Accepts healthy volunteers

Enovis High Ankle Sprain Brace Testing

NCT06719609
Conditions
Athletes in Cutting Sports
Interventions
Ankle tape, Standard lace-up ankle brace, Standard high ankle-sprain (HAS) brace, Low-profile HAS brace, No ankle brace or tape
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 40 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Completed Not applicable Interventional Results available

A Study of B + L Ophthalmic Viscosurgical Device (OVD) CVisc50

NCT04192630
Conditions
Cataract
Interventions
CVisc50 OVD, ProVisc OVD, Cataract Surgery
Device · Procedure
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
45 Years and older
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
22
States / cities
Chandler, Arizona • Phoenix, Arizona • Fayetteville, Arkansas + 18 more
Not listed Not applicable Interventional Accepts healthy volunteers

A Study of the Lifting Capacity of Fillers

NCT02974985
Conditions
Esthetic & Topographic Shifts From Facial Fillers
Interventions
injection of Restylane Lyft and Restylane L
Device
Lead sponsor
Abington Memorial Hospital
Other
Eligibility
40 Years to 60 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Plymouth Meeting, Pennsylvania
Conditions
Knee Osteoarthritis
Interventions
Hylan G-F 20, Control
Device · Other
Lead sponsor
OhioHealth
Other
Eligibility
40 Years to 70 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Dermal Nodule
Interventions
No Intervention
Other
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
2
States / cities
West Hollywood, California • New York, New York
Conditions
Cervix Cancer
Interventions
Barrigel gel spacer
Device
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Acne
Interventions
Geologie Acne Regimen - one side of face, Proactive Acne Regimen - other side of face
Combination Product
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Wrinkle
Interventions
Defyne Treatment in Nasolabial Fold, RHA3 Treatment in Nasolabial Fold
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
22 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Santa Rosa Beach, Florida