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ClinicalTrials.gov public records Last synced Sep 27, 2026, 3:49 PM EDT

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Showing 1–24 of 45 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Thyroid Eye Disease
Interventions
Hyaluronic Acid Gel injection, Saline injection
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
2
States / cities
Los Angeles, California
Completed No phase listed Interventional Accepts healthy volunteers Results available

RHA® 3 Versus Restylane-L® for Lip Augmentation

NCT04540913
Conditions
Lip Augmentation, Lip
Interventions
RHA 3, Restylane-L
Device
Lead sponsor
Teoxane SA
Industry
Eligibility
22 Years and older
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Bradenton, Florida
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Restylane Silk for Treatment of Chest Wrinkles

NCT03324997
Conditions
Wrinkle
Interventions
Restylane Silk, Saline, Optical Coherence Tomography
Drug · Device
Lead sponsor
Heidi Waldorf
Other
Eligibility
25 Years to 55 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparative Ultrasound Analysis of Two Hyaluronic Acid Dermal Fillers

NCT05622851
Conditions
Volume Deficiency of the Midface
Interventions
Restylane Contour, Juvederm Voluma
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
22 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Santa Rosa Beach, Florida
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Effectiveness of Juvederm(R) Ultra XC Injectable Gel for Lip Augmentation

NCT01197495
Conditions
Lip Augmentation
Interventions
hyaluronic acid gel
Device
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older
Enrollment
213 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Nashville, Tennessee
Completed Phase 4 Interventional Accepts healthy volunteers

A Prospective Evaluation of the Filler for Jaw Contouring

NCT06694857
Conditions
Dermal Fillers
Interventions
HA filler
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
22 Years to 55 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Lip Augmentation
Interventions
Restylane Kysse
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
22 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
3
States / cities
Los Angeles, California • Vista, California • Ardmore, Pennsylvania
Completed No phase listed Interventional Accepts healthy volunteers Results available

RHA®4 for Midface Volume Deficiency

NCT05133739
Conditions
Cheek Augmentation, Correction of Age-related Midface Contour Deficiencies
Interventions
injection of RHA®4 in Midface, injection of Comparator Product in Midface
Device
Lead sponsor
Teoxane SA
Industry
Eligibility
22 Years and older
Enrollment
201 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Completed Not applicable Interventional Results available

JUVEDERM® Ultra XC vs. Belotero Balance® for Perioral Lines

NCT01970397
Conditions
Patients With Moderate to Severe Perioral Lines
Interventions
JUVEDERM® Ultra XC, Belotero Balance®
Device
Lead sponsor
Allergan
Industry
Eligibility
35 Years and older
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Combination Facial Aesthetic Treatment in Millennials

NCT04755595
Conditions
Dermatological Non-Disease
Interventions
Botox Cosmetic Injectable Product, Juvéderm Voluma XC, Juvéderm Volbella XC
Drug · Device
Lead sponsor
State University of New York - Downstate Medical Center
Other
Eligibility
24 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Brooklyn, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Jowl Improvement With Injectable Fillers

NCT04389866
Conditions
Jowls
Interventions
JUVÉDERM VOLUMA™ XC
Device
Lead sponsor
Advanced Dermatology
Other
Eligibility
35 Years to 75 Years · Female only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Lincolnshire, Illinois
Completed Not applicable Interventional Accepts healthy volunteers Results available

RHA® 4 NLF Cannula

NCT04754646
Conditions
Wrinkle, Nasolabial Fold, Aging
Interventions
Split-face injection of RHA® 4 with a cannula into a single NLF., Split-face injection of RHA® 4 with a needle (TSK 27G x ½") into the contralateral NLF.
Device
Lead sponsor
Teoxane SA
Industry
Eligibility
22 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
4
States / cities
Encinitas, California • West Palm Beach, Florida • Chapel Hill, North Carolina + 1 more
Conditions
Intrinsic Aging of Skin
Interventions
Juvéderm Ultra, Cosmoderm 1
Device
Lead sponsor
Steven Fagien
Other
Eligibility
25 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Boca Raton, Florida
Conditions
Ethmoid Sinusitis, Rhinosinusitis
Interventions
AdvaCoat sinus gel, Merogel Injectable
Device
Lead sponsor
Carbylan Therapeutics, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
4
States / cities
Birmingham, Alabama • San Francisco, California • Chicago, Illinois + 1 more
Not listed Not applicable Interventional Accepts healthy volunteers

Restylane Silk Microinjections to Cheeks

NCT03742479
Conditions
Wrinkle
Interventions
Restylane® Silk
Device
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Diego, California
Conditions
Facial Rhytides, Crow's Feet Lines, Glabellar Lines, Nasolabial Fold
Interventions
onabotulinumtoxinA, bimatoprost ophthalmic solution 0.03%, JUVÉDERM® ULTRA XC, JUVÉDERM® ULTRA PLUS XC, JUVÉDERM® VOLUMA® XC
Biological · Drug · Device
Lead sponsor
Allergan
Industry
Eligibility
35 Years to 65 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effectiveness and Safety of Restylane Lyft With Lidocaine in the Dorsal Hand

NCT02650921
Conditions
Volume Deficit in the Hand
Interventions
Restylane Lyft with Lidocaine
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
22 Years and older
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
7
States / cities
Vista, California • Boulder, Colorado • Englewood, Colorado + 4 more
Conditions
Prostate Cancer
Interventions
Cross-linked hyaluronan gel
Device
Lead sponsor
Cancer Center of Irvine
Other
Eligibility
18 Years and older · Male only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Irvine, California
Conditions
Temple Hollowing
Interventions
Juvéderm® VOLUMA XC
Device
Lead sponsor
Allergan
Industry
Eligibility
22 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Jawline Definition
Interventions
VOLUX XC, No-treatment control
Device · Other
Lead sponsor
Allergan
Industry
Eligibility
22 Years and older
Enrollment
206 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
19
States / cities
Birmingham, Alabama • Los Angeles, California • Santa Rosa, California + 14 more
Conditions
Lip Augmentation
Interventions
PN40082
Device
Lead sponsor
Prollenium Medical Technologies Inc.
Industry
Eligibility
21 Years and older
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
5
States / cities
Encinitas, California • Miami, Florida • Omaha, Nebraska + 2 more
Conditions
Fine Lines, Wrinkle, Facial Laxity, Volume Loss
Interventions
Obagi® Saypha® MagIQ™ Injectable Hyaluronic Acid
Other
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
30 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
San Diego, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

RHA Redensity - Perioral Rhytids

NCT03092219
Conditions
Perioral Rhytids, Aging, Wrinkle
Interventions
TEOSYAL RHA Redensity
Device
Lead sponsor
Teoxane SA
Industry
Eligibility
22 Years and older
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
6
States / cities
Beverly Hills, California • Santa Monica, California • Coral Gables, Florida + 3 more
Conditions
Prostate Cancer
Interventions
Barrigel, Transrectal Ultrasound
Device
Lead sponsor
Palette Life Sciences, Inc.
Industry
Eligibility
18 Years and older · Male only
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
4
States / cities
Boston, Massachusetts • Clifton, New Jersey • Austin, Texas + 1 more