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Showing 1–24 of 59 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Hyaluronic Acid filler Clear all
Completed No phase listed Observational Accepts healthy volunteers

The Strategic Use of Hyaluronic Acid Fillers and Neurotoxin to Influence Gender Perception in Transgender Individuals

NCT04478214
View directory record Official record
Conditions
Gender Dysphoria
Interventions
Not listed
Lead sponsor
Mountain Dermatology Specialists
Other
Eligibility
18 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 19, 2020 · Synced Sep 24, 2026, 5:32 AM EDT
Not yet recruiting Phase 2 Interventional Accepts healthy volunteers

Assess Impact of Microdroplet Hyaluronic Acid Filler on Skin Quality in Patients on Glucagon-like Peptide-1 Agonists

NCT07221461
View directory record Official record
Conditions
Wrinkle
Interventions
Skinvive
Device
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
25 Years to 50 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Sep 24, 2026, 5:32 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Pain With Belotero® Balance With Integral Lidocaine for Correction of the Nasolabial Folds

NCT03319719
View directory record Official record
Conditions
Correction of Moderate to Severe Nasolabial Folds
Interventions
Belotero® Balance with integral lidocaine, Belotero® Balance
Device
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Nashville, Tennessee • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Sep 30, 2019 · Synced Sep 24, 2026, 5:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Study to Evaluate the Safety of Retreatment With Restylane® Lyft With Lidocaine for Augmentation of the Chin Region

NCT07566286
View directory record Official record
Conditions
Chin Augmentation
Interventions
Restylane Lyft with Lidocaine
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
22 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
8
States / cities
Westport, Connecticut • Boynton Beach, Florida • Coral Gables, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 24, 2026, 5:32 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

A Prospective Evaluation of the Filler for Jaw Contouring

NCT06694857
View directory record Official record
Conditions
Dermal Fillers
Interventions
HA filler
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
22 Years to 55 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Sep 24, 2026, 5:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Comparative Analysis of Two Hyaluronic Acid Fillers for Nasolabial Fold Correction

NCT06351293
View directory record Official record
Conditions
Wrinkle
Interventions
Defyne Treatment in Nasolabial Fold, RHA3 Treatment in Nasolabial Fold
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
22 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Santa Rosa Beach, Florida
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Sep 24, 2026, 5:32 AM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Restylane Silk for Treatment of Chest Wrinkles

NCT03324997
View directory record Official record
Conditions
Wrinkle
Interventions
Restylane Silk, Saline, Optical Coherence Tomography
Drug · Device
Lead sponsor
Heidi Waldorf
Other
Eligibility
25 Years to 55 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 5, 2018 · Synced Sep 24, 2026, 5:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Shafer Width and Girth: The Use of Injectable Fillers for Penile Enhancement

NCT04755634
View directory record Official record
Conditions
Micropenis
Interventions
Hyaluronic Acid
Device
Lead sponsor
Shafer Clinic Fifth Avenue
Network
Eligibility
21 Years to 65 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 24, 2026, 5:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Restylane Refyne for Correction of Horizontal Neck Rhytides

NCT04162496
View directory record Official record
Conditions
Aging, Wrinkle, Rhytides
Interventions
Restylane Refyne
Device
Lead sponsor
Siperstein Dermatology
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boynton Beach, Florida
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Sep 24, 2026, 5:32 AM EDT
Completed Phase 3 Interventional Results available

A Safety and Effectiveness of VOLBELLA XC Hyaluronic Acid (HA) Injectable Gel to Correct Infraorbital Hollowing

NCT03418545
View directory record Official record
Conditions
Infraorbital Hollowing
Interventions
JUVÉDERM VOLBELLA® XC injectable gel
Device
Lead sponsor
Allergan
Industry
Eligibility
22 Years and older
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
15
States / cities
Beverly Hills, California • Newport Beach, California • San Diego, California + 11 more
Source: ClinicalTrials.gov public record
Updated Nov 14, 2021 · Synced Sep 24, 2026, 5:32 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Retrospective Evaluation of Combination Treatment With the Ulthera System

NCT02444169
View directory record Official record
Conditions
Skin Laxity
Interventions
Ultherapy, Incobotulinumtoxin A, Radiesse, Belotero Balance
Device · Drug
Lead sponsor
Ulthera, Inc
Industry
Eligibility
25 Years to 70 Years
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
5
States / cities
Laguna Beach, California • San Diego, California • Coral Gables, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Sep 24, 2026, 5:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

RHA® Redensity Eye Versus No-treatment for the Infra-Orbital Hollows

NCT04577898
View directory record Official record
Conditions
Infra-orbital Hollows, Tear-trough Deformity, Wrinkle
Interventions
RHA® Redensity Eye
Device
Lead sponsor
Teoxane SA
Industry
Eligibility
22 Years and older
Enrollment
248 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
4
States / cities
Encino, California • Santa Monica, California • Coral Gables, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced Sep 24, 2026, 5:32 AM EDT
Completed No phase listed Interventional Accepts healthy volunteers Results available

RHA®4 for Midface Volume Deficiency

NCT05133739
View directory record Official record
Conditions
Cheek Augmentation, Correction of Age-related Midface Contour Deficiencies
Interventions
injection of RHA®4 in Midface, injection of Comparator Product in Midface
Device
Lead sponsor
Teoxane SA
Industry
Eligibility
22 Years and older
Enrollment
201 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2025 · Synced Sep 24, 2026, 5:32 AM EDT
Completed Not applicable Interventional Results available

TEOSYAL® RHA Ultra Deep and Perlane-L® for the Correction of Nasolabial Folds

NCT02253147
View directory record Official record
Conditions
Nasolabial Folds, Wrinkles
Interventions
TEOSYAL® RHA Ultra Deep
Device
Lead sponsor
Teoxane SA
Industry
Eligibility
22 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
4
States / cities
Beverly Hills, California • Bradenton, Florida • Chapel Hill, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2018 · Synced Sep 24, 2026, 5:32 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Study of the Lifting Capacity of Fillers

NCT02974985
View directory record Official record
Conditions
Esthetic & Topographic Shifts From Facial Fillers
Interventions
injection of Restylane Lyft and Restylane L
Device
Lead sponsor
Abington Memorial Hospital
Other
Eligibility
40 Years to 60 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Plymouth Meeting, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 9, 2018 · Synced Sep 24, 2026, 5:32 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Combination Facial Aesthetic Treatment in Millennials

NCT04755595
View directory record Official record
Conditions
Dermatological Non-Disease
Interventions
Botox Cosmetic Injectable Product, Juvéderm Voluma XC, Juvéderm Volbella XC
Drug · Device
Lead sponsor
State University of New York - Downstate Medical Center
Other
Eligibility
24 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Sep 24, 2026, 5:32 AM EDT
Completed Not applicable Interventional Results available

TEOSYAL® RHA Global Action, TEOSYAL® RHA Deep Lines, and Juvéderm® Ultra XC for the Correction of Nasolabial Folds

NCT02195427
View directory record Official record
Conditions
Nasolabial Folds, Wrinkles
Interventions
TEOSYAL® RHA Global Action, TEOSYAL® RHA Deep Lines
Device
Lead sponsor
Teoxane SA
Industry
Eligibility
22 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
5
States / cities
Birmingham, Alabama • Beverly Hills, California • Santa Monica, California + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 24, 2018 · Synced Sep 24, 2026, 5:32 AM EDT
Completed Not applicable Interventional Results available

Safety and Effectiveness of Belotero® in Subjects With Fitzpatrick Phototypes IV Through VI

NCT00922623
View directory record Official record
Conditions
Facial Wrinkles
Interventions
Belotero®
Device
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
3
States / cities
Los Angeles, California • Mitchellville, Maryland • Montclair, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 25, 2013 · Synced Sep 24, 2026, 5:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Effectiveness of Restylane Lyft With Lidocaine for Augmentation of the Chin Region to Improve the Chin Profile

NCT05777759
View directory record Official record
Conditions
Chin Augmentation, Chin Retrusion
Interventions
Restylane Lyft with Lidocaine, Juvederm Voluma XC
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
22 Years and older
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
11
States / cities
Los Angeles, California • Manhattan Beach, California • Westport, Connecticut + 8 more
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 24, 2026, 5:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

GAL1704 for Cheek Augmentation and Correction of Midface Contour Deficiencies

NCT03700047
View directory record Official record
Conditions
Cheek Augmentation
Interventions
GAL1704, Juvederm Voluma
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
22 Years and older
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
15
States / cities
Los Angeles, California • Sacramento, California • Solana Beach, California + 11 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Sep 24, 2026, 5:32 AM EDT
Withdrawn Phase 4 Interventional

Hyaluronic Acid Gels for Lower Lid Retraction

NCT01838252
View directory record Official record
Conditions
Ectropion
Interventions
Hyaluronic acid, Saline
Procedure
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 2, 2014 · Synced Sep 24, 2026, 5:32 AM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Use of Tranexamic Acid in Facial Fillers

NCT04373603
View directory record Official record
Conditions
Injection Site Bruising
Interventions
Tranexamic acid, Saline, Hyaluronic acid
Drug · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 89 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 25, 2022 · Synced Sep 24, 2026, 5:32 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Reducing and Removing Hyaluronic Acid Filler With Hyaluronidase

NCT01722916
View directory record Official record
Conditions
Drug Safety
Interventions
Hyaluronidase
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 24, 2026, 5:32 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Rejuvenation of the Lower Eyelid Using a Combination of Two Hyaluronic Acid Fillers - a Pilot Study

NCT00852241
View directory record Official record
Conditions
Infraorbital Hollows
Interventions
Restalyne, Perlane
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 11, 2018 · Synced Sep 24, 2026, 5:32 AM EDT