- Conditions
- Subjects Requesting and Requiring Facial Rejuvenation With Neurotoxins and/or Hyaluronic Acid Fillers
- Interventions
- NuDerm® System, Placebo
- Other
- Lead sponsor
- DeNova Research
- Other
- Eligibility
- 25 Years to 60 Years · Female only
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 25–48
of 24
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Rhytids, Wrinkles
- Interventions
- hyaluronic acid or calcium hydroxylapatite filler
- Device
- Lead sponsor
- The New York Eye & Ear Infirmary
- Other
- Eligibility
- Not listed
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Gastrointestinal Microbiome
- Interventions
- Hyaluronan
- Dietary Supplement
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Breast Cancer, Vulvovaginal Signs and Symptoms, Sexual Desire Disorder, Body Image
- Interventions
- Hyaluronic acid (HLA) Vaginal Moisturizer, Polycarbophil Vaginal Moisturizer, Hypnotic Relaxation, Progressive Muscle Relaxation (PMR)
- Device · Behavioral
- Lead sponsor
- The University of Tennessee, Knoxville
- Other
- Eligibility
- 18 Years to 99 Years · Female only
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Knoxville, Tennessee
- Conditions
- Venous Leg Ulcer, Chronic Wounds
- Interventions
- Hyalomatrix, Standard of Care
- Device · Other
- Lead sponsor
- NuScience Medical Biologics, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 122 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 4
- States / cities
- Alexandria, Louisiana • Pineville, Louisiana • Vidalia, Louisiana + 1 more
- Conditions
- Wrinkle
- Interventions
- Defyne Treatment in Nasolabial Fold, RHA3 Treatment in Nasolabial Fold
- Device
- Lead sponsor
- Galderma R&D
- Industry
- Eligibility
- 22 Years to 65 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Santa Rosa Beach, Florida
- Conditions
- Chondromalacia Patella, Patellofemoral Pain Syndrome
- Interventions
- Synvisc-One™, Sham Treatment
- Device · Other
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 15 Years to 45 Years
- Enrollment
- 86 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2016
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Knee Osteoarthritis
- Interventions
- HYMOVIS, Placebo
- Device
- Lead sponsor
- Fidia Farmaceutici s.p.a.
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 332 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 21
- States / cities
- Birmingham, Alabama • Brimingham, Alabama • Phoenix, Arizona + 17 more
- Conditions
- Refractive Error - Myopia Bilateral
- Interventions
- Hioxifilcon A standard hydrogel contact lens with Hyaluronic Acid (HA)
- Device
- Lead sponsor
- Vision Service Plan
- Industry
- Eligibility
- 18 Years to 42 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020
- U.S. locations
- 3
- States / cities
- Atlanta, Georgia • Westerville, Ohio • Brentwood, Tennessee
- Conditions
- Joint Pain
- Interventions
- Joint Health Product, Placebo, Glucosamine / Chondroitin
- Dietary Supplement
- Lead sponsor
- U.S. Nutraceuticals, LLC
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 135 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2011
- U.S. locations
- 1
- States / cities
- Sausalito, California
- Conditions
- Prostate Cancer
- Interventions
- Cross-linked hyaluronan gel
- Device
- Lead sponsor
- Cancer Center of Irvine
- Other
- Eligibility
- 18 Years and older · Male only
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 1
- States / cities
- Irvine, California
- Conditions
- Glenohumeral Osteoarthritis
- Interventions
- Orthovisc, Control
- Device · Drug
- Lead sponsor
- DePuy Mitek
- Industry
- Eligibility
- 25 Years to 75 Years
- Enrollment
- 274 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2011
- U.S. locations
- 13
- States / cities
- Encinitas, California • Fresno, California • Coral Gables, Florida + 10 more
- Conditions
- Metastatic Colorectal Cancer
- Interventions
- CA102N, TAS-102, Bevacizumab
- Drug · Biological
- Lead sponsor
- Holy Stone Healthcare Co., Ltd
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2027 – 2031
- U.S. locations
- 1
- States / cities
- Gilbert, Arizona
- Conditions
- Prostate Cancer
- Interventions
- Barrigel, Transrectal Ultrasound
- Device
- Lead sponsor
- Palette Life Sciences, Inc.
- Industry
- Eligibility
- 18 Years and older · Male only
- Enrollment
- 84 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 11
- States / cities
- Chandler, Arizona • Santa Barbara, California • Boca Raton, Florida + 8 more
- Conditions
- Osteoarthritis, Knee
- Interventions
- Platelet-rich Plasma (PRP), Hyaluronic Acid
- Biological
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 111 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2015
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Dry Eye, Eye Diseases, Eyes Dry Chronic
- Interventions
- Autologous Serum Tears (50% Autologous Serum Tears + 0.2% Sodium Hyaluronate), Biological - Autologous Serum Tears (50% Autologous Serum Tears + Balanced Saline Solution (BSS), Standard of Care (SOC) Treatment
- Biological · Other
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Dry Eye
- Interventions
- Lacrifill
- Drug
- Lead sponsor
- Vision Innovation Centers of Pennsylvania, LLC d/b/a Eye Care Specialists
- Other
- Eligibility
- 22 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Kingston, Pennsylvania
- Conditions
- Cataract
- Interventions
- DisCoVisc, DuoVisc, Healon5, Amvisc Plus
- Device
- Lead sponsor
- Alcon Research
- Industry
- Eligibility
- 50 Years and older
- Enrollment
- 112 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2007
- U.S. locations
- 1
- States / cities
- Fort Worth, Texas
- Conditions
- Osteoarthritis
- Interventions
- hyaluronate intra-articular injection, placebo injection
- Device
- Lead sponsor
- Henry DeGroot, M.D.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 69 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 1
- States / cities
- Newton, Massachusetts
- Conditions
- Wrinkle
- Interventions
- Cleansing Balm, Facial Serum, Moisturizer
- Other
- Lead sponsor
- Integrative Skin Science and Research
- Industry
- Eligibility
- 35 Years to 65 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023
- U.S. locations
- 1
- States / cities
- Sacramento, California
- Conditions
- Perioral Rejuvenation, Upper Lip Projection
- Interventions
- Restylane® Defyne
- Device
- Lead sponsor
- DeNova Research
- Other
- Eligibility
- 21 Years to 70 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Lacerations, Pain, Procedural, LET
- Interventions
- LET Lidocaine (4%), Epinephrine (0.1%), and Tetracaine (0.5%) topical gel
- Drug
- Lead sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
- Other
- Eligibility
- 7 Years to 17 Years
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 2
- States / cities
- Orange, California • Torrance, California
- Conditions
- Adhesions, Cesarean Section, Delivery, Obstetric
- Interventions
- modified sodium hyaluronic acid and carboxymethylcellulose, Placebo
- Device
- Lead sponsor
- Winthrop University Hospital
- Other
- Eligibility
- 18 Years to 55 Years · Female only
- Enrollment
- 753 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2014
- U.S. locations
- 3
- States / cities
- Mineola, New York • Stony Brook, New York • Allentown, Pennsylvania
- Conditions
- Acne, Acne Scars, AdverseEvent
- Interventions
- Restylane Silk, 1.0 ml, Saline, 1.0 ml
- Device
- Lead sponsor
- Schweiger Dermatology, PLLC
- Industry
- Eligibility
- 22 Years to 55 Years
- Enrollment
- 26 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- New York, New York